Citations for
1HSPB1, SMURF2
Ubiquitination of heat shock protein 27 is mediated by its interaction with Smad ubiquitination regulatory factor 2 in A549 cells.
Sun Y, Zhou M, Fu D, Xu B, Fang T, Ma Y, Chen J, Zhang J.
Exp Lung Res 37(9):568-73. Epub 2011 Oct 3. 2011
2CMT2F, HDAC6, HSPB1
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease.
d'Ydewalle C, Krishnan J, Chiheb DM, Van Damme P, Irobi J, Kozikowski AP, Vanden Berghe P, Timmerman V, Robberecht W, Van Den Bosch L.
Nat Med 17(8):968-74. doi: 10.1038/nm.2396. 2011
3CMT2F, HSPB1
Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.
Almeida-Souza L, Asselbergh B, d'Ydewalle C, Moonens K, Goethals S, de Winter V, Azmi A, Irobi J, Timmermans JP, Gevaert K, Remaut H, Van Den Bosch L, Timmerman V, Janssens S.
J Neurosci 31(43):15320-8. doi: 10.1523/JNEUROSCI.3266-11.2011. 2011
4BGLAP, HSPB1
Regulation by heat shock protein 27 of osteocalcin synthesis in osteoblasts.
Kato K, Adachi S, Matsushima-Nishiwaki R, Minamitani C, Natsume H, Katagiri Y, Hirose Y, Mizutani J, Tokuda H, Kozawa O, Otsuka T.
Endocrinology 152(5):1872-82. doi: 10.1210/en.2010-1062. Epub 2011 Mar 22. 2011
5HSPB1, HSPB2
Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane.
Razandi M, Pedram A, Levin ER.
Mol Cell Biol 30(13):3249-61. Epub 2010 May 3.PMID: 20439495 2010
6HSPB1, MAP3K12
The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper-bearing kinase expression.
Robitaille H, Simard-Bisson C, Larouche D, Tanguay RM, Blouin R, Germain L.
J Invest Dermatol 130(1):74-85. Epub . 2010
7HSPB1
Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection.
Friedman MJ, Li S, Li XJ.
J Biol Chem 284(41):27944-51. Epub 2009 Aug 5.PMID: 19656944 2009
8HSPB1
Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement.
Foster CS, Dodson AR, Ambroisine L, Fisher G, Møller H, Clark J, Attard G, De-Bono J, Scardino P, Reuter VE, Cooper CS, Berney DM, Cuzick J.
Br J Cancer 101(7):1137-44. Epub 2009 Aug 25.PMID: 19707199 2009
9HSPB1
Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity.
Brunet Simioni M, De Thonel A, Hammann A, Joly AL, Bossis G, Fourmaux E, Bouchot A, Landry J, Piechaczyk M, Garrido C.
Oncogene 28(37):3332-44. Epub 2009 Jul 13.PMID: 19597476 2009
10HSPB1
The level of Hsp27 in lymphocytes is negatively associated with a higher risk of lung cancer.
Wang F, Feng M, Xu P, Xiao H, Niu P, Yang X, Bai Y, Peng Y, Yao P, Tan H, Tanguay RM, Wu T.
Cell Stress Chaperones 14(3):245-51. Epub 2008 Sep 18.PMID: 18800238 2009
11HSPB1
Serum heat shock protein 27 is increased in chronic pancreatitis and pancreatic carcinoma.
Liao WC, Wu MS, Wang HP, Tien YW, Lin JT.
Pancreas 38(4):422-6.PMID: 19214136 2009
12HSPB1
Transduced HSP27 protein protects neuronal cell death by enhancing FALS-associated SOD1 mutant activity.
An JJ, Lee YP, Kim DW, Sohn EJ, Jeong HJ, Kang HW, Shin MJ, Kim MJ, Ahn EH, Jang SH, Kang JH, Kang TC, Won MH, Kwon OS, Cho SW, Lee KS, Park J, Eum WS, Choi SY.
BMB Rep 42(3):136-41.PMID: 19335999 2009
13HSPB1
Elevated HSP27, HSP70 and HSP90 alpha in chronic obstructive pulmonary disease: markers for immune activation and tissue destruction.
Hacker S, Lambers C, Hoetzenecker K, Pollreisz A, Aigner C, Lichtenauer M, Mangold A, Niederpold T, Zimmermann M, Taghavi S, Klepetko W, Ankersmit HJ.
Clin Lab 55(1-2):31-40.PMID: 19350847 2009
14AR, HSPB1, PRKD1
Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
Hassan S, Biswas MH, Zhang C, Du C, Balaji KC.
Oncogene 28(49):4386-96. Epub .PMID: 19767773 2009
15HSPB1, MAPKAPK5
PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5.
Kostenko S, Johannessen M, Moens U.
Cell Signal 21(5):712-8. doi: 10.1016/j.cellsig.2009.01.009. Epub 2009 Jan 8. 2009
16CMT2F, HSPB1
Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2.
Houlden H, Laura M, Wavrant-De Vrièze F, Blake J, Wood N, Reilly MM.
Neurology 71(21):1660-8. Epub 2008 Oct 1.PMID: 18832141 2008
17HSPB1
Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A.
Rayner K, Chen YX, McNulty M, Simard T, Zhao X, Wells DJ, de Belleroche J, O'Brien ER.
Circ Res 103(2):133-41. Epub 2008 Jun 19.PMID: 18566345 2008
18HSPB1
Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer.
Tsuruta M, Nishibori H, Hasegawa H, Ishii Y, Endo T, Kubota T, Kitajima M, Kitagawa Y.
Oncol Rep 20(5):1165-72.PMID: 18949417 2008
19HSPB1
Heat shock protein 27 expression in the human testis showing normal and abnormal spermatogenesis.
Adly MA, Assaf HA, Hussein MR.
Cell Biol Int 32(10):1247-55. Epub 2008 Jul 23.PMID: 18692580 2008
20CMT2F, HSPB1
Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27).
James PA, Rankin J, Talbot K.
J Neurol Neurosurg Psychiatry 79(4):461-3.PMID: 18344398 2008
21HSPB1, CMT2F
A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.
Ackerley S, James PA, Kalli A, French S, Davies KE, Talbot K.
Hum Mol Genet 15(2):347-54. Epub 2005 Dec 20. 2006
22ALXD1, GFAP, CRYAB, HSPB1
The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27.
Der Perng M, Su M, Wen SF, Li R, Gibbon T, Prescott AR, Brenner M, Quinlan RA.
Am J Hum Genet 79(2):197-213. Epub 2006 Jun 12. 2006
23HSPB1
Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome.
Park HK, Park EC, Bae SW, Park MY, Kim SW, Yoo HS, Tudev M, Ko YH, Choi YH, Kim S, Kim DI, Kim YW, Lee BB, Yoon JB, Park JE.
Circulation 114(9):886-93. Epub 2006 Aug 21. 2006
24CRYAB, HSPB1, HSPB3, HSPB6, HSPB8
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3.
Fontaine JM, Sun X, Benndorf R, Welsh MJ.
Biochem Biophys Res Commun 337(3):1006-11. Epub 2005 Oct 3. 2005
25HSPB1, HSPB2
A protective role of 27-kDa heat shock protein in glucocorticoid-evoked apoptotic cell death of hippocampal progenitor cells.
Son GH, Geum D, Chung S, Park E, Lee KH, Choi S, Kim K.
Biochem Biophys Res Commun 338(4):1751-8. Epub 2005 Nov 2. 2005
26HSPB1, CMT2F
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Evgrafov OV, Mersiyanova I, Irobi J, Van Den Bosch L, Dierick I, Leung CL, Schagina O, Verpoorten N, Van Impe K, Fedotov V, Dadali E, Auer-Grumbach M, Windpassinger C, Wagner K, Mitrovic Z, Hilton-Jones D, Talbot K, Martin JJ, Vasserman N, Tverskaya S, Polyakov A, Liem RK, Gettemans J, Robberecht W, De Jonghe P, Timmerman V.
Nat Genet 36(6):602-6. Epub 2004 May 02. 2004
27HSPB8, HSPB1
Interaction of human HSP22 (HSPB8) with other small heat shock proteins.
Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R.
J Biol Chem 279(4):2394-402. Epub 2003 Oct 31. 2004
28HSPB1, LACTB
Differential expression of a novel gene in response to hsp27 and cell differentiation in human keratinocytes.
Hell-Pourmojib M, Neuner P, Fischer H, Rezaie S, Kindas-Mugge I, Knobler R, Trautinger F.
J Invest Dermatol 119(1):154-9. 2002
29CRYAA,CRYAB,HSPBL1,HSPBL2,HSPBL3,HSPB1,HSPB2,HSPB3,HSPB7
Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides.
Leroux MR, Melki R, Gordon B, Batelier G, Candido EP.
J Biol Chem 272(39):24646-56 1997
30HSPB1
The 29-kDa proteins phosphorylated in thrombin-activated human platelets are forms of the estrogen receptor-related 27-kDa heat shock protein.
Mendelsohn ME, Zhu Y, O'Neill S.
Proc Natl Acad Sci U S A 88(24):11212-6 1991
31HSPB1
cDNA sequence of a human heat shock protein HSP27.
Carper SW, Rocheleau TA, Storm FK.
Nucleic Acids Res 18(21):6457. No abstract available 1990
32CRYAA,CRYAB,HSPBL1,HSPBL2,HSPBL3,HSPB1,HSPB2,HSPB3,HSPB7
Sequence and organization of genes encoding the human 27 kDa heat shock protein.
Hickey E, Brandon SE, Potter R, Stein G, Stein J, Weber LA.
Nucleic Acids Res 14(10):4127-45 1986