| 1 | CANX, HSPA5
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| KDELR2 Competes with Measles Virus Envelope Proteins for Cellular Chaperones Reducing Their Chaperone-Mediated Cell Surface Transport.
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| Tiwarekar V, Fehrholz M, Schneider-Schaulies J.
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| Viruses 11(1). pii: E27. doi: 10.3390/v11010027.
2019
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| 2 | HSPA5, OTUD3
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| The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis
|
| Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, Yao Y, Li X, Liu C, Yu X, Liu Z, Cui CP, Han C, Zhang L.
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| Nat Commun. Jul 2;10(1):2914. doi: 10.1038/s41467-019-10824-7. 2019
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| 3 | HSP90AA1, HSPA5, PRDM14
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| PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.
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| Moriya C, Taniguchi H, Nagatoishi S, Igarashi H, Tsumoto K, Imai K.
|
| Cancer Sci 109(2):373-383. doi: 10.1111/cas.13458. Epub 2017 Dec 28.
2018
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| 4 | HSPA5, MUL1
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| HSPA5 negatively regulates lysosomal activity through ubiquitination of MUL1 in head and neck cancer.
|
| Kim SY, Kim HJ, Kim HJ, Kim DH, Han JH, Byeon HK, Lee K, Kim CH.
|
| Autophagy 14(3):385-403. doi: 10.1080/15548627.2017.1414126. Epub 2018 Feb 21.
2018
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| 5 | ATE1, HSPA5
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| The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation.
|
| Shim SM, Choi HR, Sung KW, Lee YJ, Kim ST, Kim D, Mun SR, Hwang J, Cha-Molstad H, Ciechanover A, Kim BY, Kwon YT.
|
| Sci Signal. Jan 2;11(511):eaan0630. doi: 10.1126/scisignal.aan0630 2018
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| 6 | ADAM17, HSPA5, PDIA6
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| GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivation.
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| Schäfer M, Granato DC, Krossa S, Bartels AK, Yokoo S, Düsterhöft S, Koudelka T, Scheidig AJ, Tholey A, Paes Leme AF, Grötzinger J, Lorenzen I.
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| FEBS Lett 591(21):3567-3587. doi: 10.1002/1873-3468.12858. Epub 2017 Oct 11.
2017
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| 7 | HSPA5, METTL21A
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| Lysine trimethylation regulates 78-kDa glucose-regulated protein proteostasis during endoplasmic reticulum stress
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| Sieber J, Wieder N, Ostrosky-Frid M, Dvela-Levitt M, Aygün O, Udeshi ND, Carr SA, Greka A.
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| J Biol Chem. Nov 17;292(46):18878-18885. doi: 10.1074/jbc.M117.797084. Epub 2017 Sep 14 2017
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| 8 | ATAD3A, HSPA5, WASF3
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| Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein.
|
| Teng Y, Ren X, Li H, Shull A, Kim J, Cowell JK.
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| Oncogene 35(3):333-43. doi: 10.1038/onc.2015.86.
2016
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| 9 | HSPA5, INPP5K, PAK1
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| Glucose-regulated protein 78 (GRP78) binds directly to PIP3 phosphatase SKIP and determines its localization.
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| Ijuin T, Hatano N, Takenawa T.
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| Genes Cells 21(5):457-65. doi: 10.1111/gtc.12353. Epub 2016 Mar 4.
2016
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| 10 | CRELD2, HSPA5, MANF
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| Characterization of the Role of MANF in Regulating the Secretion of CRELD2.
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| Oh-Hashi K, Norisada J, Hirata Y, Kiuchi K.
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| Biol Pharm Bull 38(5):722-31. doi: 10.1248/bpb.b14-00825.
2015
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| 11 | HSPA5, SEC61
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| Protein transport into the human endoplasmic reticulum.
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| Dudek J, Pfeffer S, Lee PH, Jung M, Cavalié A, Helms V, Förster F, Zimmermann R.
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| J Mol Biol 427(6 Pt A):1159-75. doi: 10.1016/j.jmb.2014.06.011. Epub 2014 Jun 23. Review.
2015
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| 12 | ATE1, HSPA5
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| Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
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| Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT.
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| Nat Cell Biol. Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15 2015
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| 13 | DNAJC3, HSPA5, JDND
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| Absence of BiP Co-chaperone DNAJC3 Causes Diabetes Mellitus and Multisystemic Neurodegeneration.
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| Synofzik M, Haack TB, Kopajtich R, Gorza M, Rapaport D, Greiner M, Schönfeld C, Freiberg C, Schorr S, Holl RW, Gonzalez MA, Fritsche A, Fallier-Becker P, Zimmermann R, Strom TM, Meitinger T, Züchner S, Schüle R, Schöls L, Prokisch H.
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| Am J Hum Genet 95(6):689-97. doi: 10.1016/j.ajhg.2014.10.013. Epub 2014 Nov 20.
2014
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| 14 | HSPA5, SNCA
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| GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein.
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| Bellani S, Mescola A, Ronzitti G, Tsushima H, Tilve S, Canale C, Valtorta F, Chieregatti E.
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| Cell Death Differ 21(12):1971-83. doi: 10.1038/cdd.2014.111. Epub 2014 Aug 15.
2014
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| 15 | HSPA5, TDGF1
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| CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.
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| Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC.
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| Stem Cell Reports 2(4):427-39. doi: 10.1016/j.stemcr.2014.02.010.
2014
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| 16 | ATF6, HSPA5, RRBP1
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| Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78.
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| Tsai HY, Yang YF, Wu AT, Yang CJ, Liu YP, Jan YH, Lee CH, Hsiao YW, Yeh CT, Shen CN, Lu PJ, Huang MS, Hsiao M.
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| Oncogene 32(41):4921-31. doi: 10.1038/onc.2012.514. Epub 2013 Jan 14.
2013
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| 17 | AGR2, HSPA5
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| Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78.
|
| Ryu J, Park SG, Lee PY, Cho S, Lee do H, Kim GH, Kim JH, Park BC.
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| Biochem Biophys Res Commun 430(2):610-5. doi: 10.1016/j.bbrc.2012.11.105. Epub 2012 Dec 4.
2013
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| 18 | DNAJB11, HSPA5, SLC61A1
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| ERdj3 regulates BiP occupancy in living cells.
|
| Guo F, Snapp EL.
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| J Cell Sci 126(Pt 6):1429-39. doi: 10.1242/jcs.118182. Epub 2013 Feb 1.
2013
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| 19 | HSPA5, PAWR
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| Role of prostate apoptosis response 4 in translocation of GRP78 from the endoplasmic reticulum to the cell surface of trophoblastic cells.
|
| Cohen M, Ribaux P, Epiney M, Irion O.
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| PLoS One 8(11):e80231. doi: 10.1371/journal.pone.0080231. eCollection 2013.
2013
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| 20 | EIF2AK3, ERN1, HSPA5
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| Binding of human BiP to the ER stress transducers IRE1 and PERK requires ATP.
|
| Sou SN, Ilieva KM, Polizzi KM.
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| Biochem Biophys Res Commun 420(2):473-8. Epub 2012 Mar 13. 2012
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| 21 | DMKN, HSPA5
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| Dermokine-β impairs ERK signaling through direct binding to GRP78.
|
| Higashi K, Hasegawa M, Yokoyama C, Tachibana T, Mitsui S, Saito K.
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| FEBS Lett 586(16):2300-5. doi: 10.1016/j.febslet.2012.06.022. Epub 2012 Jun 23. 2012
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| 22 | HSPA5, MSS, SIL1
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| C-terminal mutations destabilize SIL1/BAP and can cause Marinesco-Sjögren syndrome.
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| Howes J, Shimizu Y, Feige MJ, Hendershot LM.
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| J Biol Chem 287(11):8552-60. doi: 10.1074/jbc.M111.333286. Epub 2012 Jan 4.
2012
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| 23 | HSP90B1, HSPA5, TLR4
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| Chaperone insufficiency links TLR4 protein signaling to endoplasmic reticulum stress.
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| Coope A, Milanski M, Arruda AP, Ignacio-Souza LM, Saad MJ, Anhê GF, Velloso LA.
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| J Biol Chem 287(19):15580-9. doi: 10.1074/jbc.M111.315218. Epub 2012 Mar 16.
2012
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| 24 | HSPA5, SEC61A1
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| BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER.
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| Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmermann R.
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| EMBO J 31(15):3282-96. doi: 10.1038/emboj.2012.189. Epub 2012 Jul 13. Erratum in: EMBO J. 2012 Sep 12;31(18):3784.
2012
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| 25 | HSPA5
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| Endoplasmic reticulum chaperone GRP78 suppresses the aggregation of proteins containing expanded polyglutamine tract.
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| Yamagishi N, Magara S, Tamura S, Saito Y, Hatayama T.
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| Biochem Biophys Res Commun 422(3):527-33. doi: 10.1016/j.bbrc.2012.05.078. Epub 2012 May 22.
2012
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| 26 | HSPA5
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| Endoplasmic reticulum chaperone GRP78 suppresses the aggregation of proteins containing expanded polyglutamine tract.
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| Yamagishi N, Magara S, Tamura S, Saito Y, Hatayama T.
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| Biochem Biophys Res Commun 422(3):527-33. doi: 10.1016/j.bbrc.2012.05.078. Epub 2012 May 22.
2012
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| 27 | GPX7, HSPA5
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| Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease.
|
| Wei PC, Hsieh YH, Su MI, Jiang X, Hsu PH, Lo WT, Weng JY, Jeng YM, Wang JM, Chen PL, Chang YC, Lee KF, Tsai MD, Shew JY, Lee WH.
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| Mol Cell 48(5):747-59. doi: 10.1016/j.molcel.2012.10.007. Epub 2012 Nov 1.
2012
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| 28 | HSPA5
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| A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis.
|
| Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS.
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| Cancer Res 71(8):2848-57. Epub 2011 Apr 5.
2011
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| 29 | ADAM7, CANX, HSPA5, ITM2B
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| Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm.
|
| Han C, Park I, Lee B, Jin S, Choi H, Kwon JT, Kwon YI, Kim do H, Park ZY, Cho C.
|
| J Cell Physiol 226(5):1186-95. doi: 10.1002/jcp.22444.
2011
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| 30 | BIK, HSPA5, PMAIP1
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| Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
|
| Zhou H, Zhang Y, Fu Y, Chan L, Lee AS.
|
| J Biol Chem 286(29):25687-96. Epub 2011 May 26.
2011
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| 31 | BCAP31, HSPA5
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| BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol.
|
| Geiger R, Andritschke D, Friebe S, Herzog F, Luisoni S, Heger T, Helenius A.
|
| Nat Cell Biol. 13(11):1305-14. 2011
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| 32 | HSPA5, SIGMAR1, SRR
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| Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons.
|
| Ha Y, Dun Y, Thangaraju M, Duplantier J, Dong Z, Liu K, Ganapathy V, Smith SB.
|
| Invest Ophthalmol Vis Sci 52(1):527-40. doi: 10.1167/iovs.10-5731. Print 2011 Jan. 2011
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| 33 | HSPA5
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| Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis.
|
| Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS.
|
| Cell Death Differ 17(3):488-98. Epub 2009 Oct 9.
2010
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| 34 | CHS1, HPS, HSPA5, LYST
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| Identification of proteins in the ceroid-like autofluorescent aggregates from liver lysosomes of Beige, a mouse model for human Chediak-Higashi syndrome.
|
| Zhang H, Mahuran DJ, Callahan JW.
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| Mol Genet Metab 99(4):389-95. Epub 2009 Dec 21. 2010
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| 35 | DNAJB1, HSPA4, HSPA5
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| The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes.
|
| Chien V, Aitken JF, Zhang S, Buchanan CM, Hickey A, Brittain T, Cooper GJ, Loomes KM.
|
| Biochem J. 432(1):113-21. 2010
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| 36 | HSPA5, PDIA2
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| GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic {beta}-Cells.
|
| Zhang L, Lai E, Teodoro T, Volchuk A.
|
| J Biol Chem 284(8):5289-98. Epub 2008 Dec 22.
2009
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| 37 | HSPA5, TDGF1
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| Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.
|
| Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC.
|
| Oncogene 28(24):2324-36. Epub 2009 May 4.
2009
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| 38 | HSPA5, PAWR
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| The tumor suppressor Par-4 activates an extrinsic pathway for apoptosis.
|
| Burikhanov R, Zhao Y, Goswami A, Qiu S, Schwarze SR, Rangnekar VM.
|
| Cell 138(2):377-88. Erratum in: Cell. 2009 Sep 4;138(5):1032.
2009
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| 39 | HSPA5, HSPH1
|
| Expression of heat shock protein 105 and 70 in malignant melanoma and benign melanocytic nevi.
|
| Park HS, Park CH, Choi BR, Lim MS, Heo SH, Kim CH, Kang SG, Whang KU, Cho MK.
|
| J Cutan Pathol 36(5):511-6. Epub 2009 Mar 30.PMID: 19476517 2009
|
| 40 | HSPA5, UGGT1
|
| Identification of HUGT1 as a potential BiP activator and a cellular target for improvement of recombinant protein production using a cDNA screening system.
|
| Ku SC, Lwa TR, Giam M, Yap MG, Chao SH.
|
| Mol Cells 27(5):577-82. doi: 10.1007/s10059-009-0078-z. Epub 2009 May 15.
2009
|
| 41 | GSK3B, HSPA5, HSPH1
|
| HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation.
|
| Meares GP, Zmijewska AA, Jope RS.
|
| Cell Signal 20(2):347-58. Epub 2007 Nov 17. 2008
|
| 42 | HSPA5
|
| T cell receptor-mediated signaling induces GRP78 expression in T cells: the implications in maintaining T cell viability.
|
| Takano S, Ando T, Hiramatsu N, Kanayama A, Maekawa S, Ohnuma Y, Enomoto N, Ogawa H, Paton AW, Paton JC, Kitamura M, Nakao A.
|
| Biochem Biophys Res Commun 371(4):762-6. Epub 2008 May 5. 2008
|
| 43 | DNAJC10, EDEM1, HSPA5
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| ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.
|
| Ushioda R, Hoseki J, Araki K, Jansen G, Thomas DY, Nagata K.
|
| Science 321(5888):569-72.
2008
|
| 44 | DMP1, HSPA5
|
| Endoplasmic reticulum chaperone protein GRP-78 mediates endocytosis of dentin matrix protein 1.
|
| Ravindran S, Narayanan K, Eapen AS, Hao J, Ramachandran A, Blond S, George A.
|
| J Biol Chem 283(44):29658-70. Epub 2008 Aug 28.
2008
|
| 45 | E2F1, HSPA5
|
| Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1.
|
| Racek T, Buhlmann S, Rüst F, Knoll S, Alla V, Pützer BM.
|
| J Biol Chem 283(49):34305-14. Epub 2008 Oct 7.
2008
|
| 46 | HSPA5, TDGF1
|
| GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
|
| Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
|
| Mol Cell Biol 28(2):666-77. Epub 2007 Nov 8.PMID: 17991893 2008
|
| 47 | HSPA5, RAF1
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| GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis.
|
| Shu CW, Sun FC, Cho JH, Lin CC, Liu PF, Chen PY, Chang MD, Fu HW, Lai YK.
|
| J Cell Physiol 215(3):627-35.PMID: 18064632 2008
|
| 48 | CASP12, HSPA5
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| Upregulation of GRP78 and caspase-12 in diastolic failing heart.
|
| Sun Y, Liu G, Song T, Liu F, Kang W, Zhang Y, Ge Z.
|
| Acta Biochim Pol 55(3):511-6. Epub 2008 Sep 12. 2008
|
| 49 | DNAJB9, DNAJC10, HSPA5, SFTPC
|
| ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C.
|
| Dong M, Bridges JP, Apsley K, Xu Y, Weaver TE.
|
| Mol Biol Cell 19(6):2620-30. doi: 10.1091/mbc.E07-07-0674. Epub 2008 Apr 9.
2008
|
| 50 | CFC1, HSPA5, TDGF1
|
| GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.
|
| Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC.
|
| Mol Cell Biol 28(2):666-77.
2008
|
| 51 | HSPA5
|
| Plasminogen structural domains exhibit different functions when associated with cell surface GRP78 or the voltage-dependent anion channel.
|
| Gonzalez-Gronow M, Kaczowka SJ, Payne S, Wang F, Gawdi G, Pizzo SV.
|
| J Biol Chem 282(45):32811-20. Epub 2007 Sep 11. 2007
|
| 52 | FKBP7, HSPA5
|
| Binding of FKBP23 to BiP in ER shown by gel filtration chromatography.
|
| Chen C, Ma H, Wang Y, Mi H.
|
| Z Naturforsch [C] 62(1-2):133-7.
2007
|
| 53 | FKBP7, HSPA5
|
| The binding of FKBP23 to BiP modulates BiP's ATPase activity with its PPIase activity.
|
| Wang Y, Han R, Wu D, Li J, Chen C, Ma H, Mi H.
|
| Biochem Biophys Res Commun 354(1):315-20. Epub 2007 Jan 8.
2007
|
| 54 | HSPA5
|
| Reduction of GRP78 expression with siRNA activates unfolded protein response leading to apoptosis in HeLa cells.
|
| Suzuki T, Lu J, Zahed M, Kita K, Suzuki N.
|
| Arch Biochem Biophys 468(1):1-14. Epub 2007 Sep 15.PMID: 17936241 2007
|
| 55 | HSPA5, LMAN2
|
| Stable interaction of the cargo receptor VIP36 with molecular chaperone BiP.
|
| Nawa D, Shimada O, Kawasaki N, Matsumoto N, Yamamoto K.
|
| Glycobiology 17(9):913-21. Epub 2007 Jun 22.
2007
|
| 56 | HSPA5
|
| Localization of GRP78 to mitochondria under the unfolded protein response.
|
| Sun FC, Wei S, Li CW, Chang YS, Chao CC, Lai YK.
|
| Biochem J 396(1):31-9. 2006
|
| 57 | ATE1, HSPA5
|
| Arginyltransferase, its specificity, putative substrates, bidirectional promoter, and splicing-derived isoforms.
|
| Hu RG, Brower CS, Wang H, Davydov IV, Sheng J, Zhou J, Kwon YT, Varshavsky A.
|
| J Biol Chem. Oct 27;281(43):32559-73. doi: 10.1074/jbc.M604355200. Epub 2006 Aug 30 2006
|
| 58 | SIL1, HSPA5
|
| Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP.
|
| Zhao L, Longo-Guess C, Harris BS, Lee JW, Ackerman SL.
|
| Nat Genet 37(9):974-9. Epub 2005 Aug 14. 2005
|
| 59 | SIL1, HSPA5, MSS
|
| The gene disrupted in Marinesco-Sjogren syndrome encodes SIL1, an HSPA5 cochaperone.
|
| Anttonen AK, Mahjneh I, Hamalainen RH, Lagier-Tourenne C, Kopra O, Waris L, Anttonen M, Joensuu T, Kalimo H, Paetau A, Tranebjaerg L, Chaigne D, Koenig M, Eeg-Olofsson O, Udd B, Somer M, Somer H, Lehesjoki AE.
|
| Nat Genet 37(12):1309-11. Epub 2005 Nov 13. 2005
|
| 60 | SIL1, HSPA5, MSS, SAR1B
|
| Mutations in SIL1 cause Marinesco-Sjogren syndrome, a cerebellar ataxia with cataract and myopathy.
|
| Senderek J, Krieger M, Stendel C, Bergmann C, Moser M, Breitbach-Faller N, Rudnik-Schoneborn S, Blaschek A, Wolf NI, Harting I, North K, Smith J, Muntoni F, Brockington M, Quijano-Roy S, Renault F, Herrmann R, Hendershot LM, Schroder JM, Lochmuller H, Topaloglu H, Voit T, Weis J, Ebinger F, Zerres K.
|
| Nat Genet 37(12):1312-4. Epub 2005 Nov 13. 2005
|
| 61 | HSPA5
|
| GRP78 expression correlates with histologic differentiation and favorable prognosis in neuroblastic tumors.
|
| Hsu WM, Hsieh FJ, Jeng YM, Kuo ML, Tsao PN, Lee H, Lin MT, Lai HS, Chen CN, Lai DM, Chen WJ.
|
| Int J Cancer 113(6):920-7. 2005
|
| 62 | KLF2, HSPA5
|
| Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases.
|
| Ahmad N, Lingrel JB.
|
| Biochemistry 44(16):6276-85. 2005
|
| 63 | HSPA5
|
| Functional polymorphisms of HSPA5: possible association with bipolar disorder.
|
| Kakiuchi C, Ishiwata M, Nanko S, Kunugi H, Minabe Y, Nakamura K, Mori N, Fujii K, Umekage T, Tochigi M, Kohda K, Sasaki T, Yamada K, Yoshikawa T, Kato T.
|
| Biochem Biophys Res Commun 336(4):1136-43. 2005
|
| 64 | DNAJC10, HSPA5
|
| ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress.
|
| Cunnea PM, Miranda-Vizuete A, Bertoli G, Simmen T, Damdimopoulos AE,Hermann S, Leinonen S, Huikko MP, Gustafsson JA, Sitia R, Spyrou G.
|
| J Biol Chem 278(2):1059-66. Epub 2002 Oct 30. 2003
|
| 65 | HSPA5, TMEM132A
|
| Cloning and characterization of a novel GRP78-binding protein in the rat brain.
|
| Oh-hashi K, Naruse Y, Amaya F, Shimosato G, Tanaka M.
|
| J Biol Chem 278(12):10531-7. Epub 2003 Jan 03. 2003
|
| 66 | ADGRG1, ALG5, APLP2, B3GNT3, BGN, C14orf1, CD151, CD99, CDH1, CDH32, CLPTM1, CNPY3, DAG1, DHX8, FXYD5, GDF15, HSP90B1, HSPA5, KRTCAP2, LAMA3, LMAN2, LYPD3, SPINT2, TEX261, TNFRSF12A
|
| Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
|
| Bonkobara M, Das A, Takao J, Cruz PD, Ariizumi K.
|
| Br J Dermatol 148(4):654-64. 2003
|
| 67 | HSPA5
|
| Molecular chaperone GRP78/BiP interacts with the large surface protein of hepatitis B virus in vitro and in vivo.
|
| Cho DY, Yang GH, Ryu CJ, Hong HJ.
|
| J Virol. 77(4):2784-8. 2003
|
| 68 | HSPA5
|
| Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B.
|
| Zhang J, Herscovitz H.
|
| J Biol Chem. 278(9):7459-68. 2003
|
| 69 | HSPA5
|
| Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation.
|
| Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS.
|
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| 71 | HSPA5, SIL1
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| BAP, a mammalian BiP-associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP.
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| 72 | CASP12, HSPA5
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| Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78.
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| FEBS Lett. 514(2-3):122-8. 2002
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| 73 | CALR, HSPA5
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| 74 | HSPA5
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| The role of Grp 78 in alpha 2-macroglobulin-induced signal transduction. Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction.
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| Misra UK, Gonzalez-Gronow M, Gawdi G, Hart JP, Johnson CE, Pizzo SV.
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| Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress.
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| Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade.
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| Song MS, Park YK, Lee JH, Park K.
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| Cancer Res 61(22):8322-30. 2001
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| 77 | CALR, HSPA5
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| The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
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| Arch Virol. 146(11):2055-68. 2001
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| 78 | ATF6, HSPA5, MBTPS1, MBTPS2, SCAP
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| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
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| Mol Cell 6(6):1355-64. 2000
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| 79 | HSPA5
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| The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome.
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| Interaction of murine BiP/GRP78 with the DnaJ homologue MTJ1.
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| 81 | HSPA5
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| Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum.
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| 82 | HSPA5
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| Binding of BiP to the processing enzyme lymphoma proprotein convertase prevents aggregation, but slows down maturation.
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| 83 | HSPA5
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| Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells.
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| Role of the 78-kDa glucose-regulated protein as an activity modulator of protein phosphatase1gamma2.
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| Biochem Biophys Res Commun 259(2):300-4. 1999
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| 85 | HSPA5
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| Calnexin and the immunoglobulin binding protein (BiP) coimmunoprecipitate with AMPA receptors.
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| Rubio ME, Wenthold RJ.
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| J Neurochem. 73(3):942-8. 1999
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| 86 | HSPA5
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| A stress-inducible rat liver endoplasmic reticulum protein, ERp29.
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| Eur J Biochem. 251(1-2):304-13. 1998
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| 87 | HSPA5
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| Mutagenesis of a potential immunoglobulin-binding protein-binding site enhances secretion of coagulation factor VIII.
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| Association of glucose-regulated protein (grp78) with human keratin 8.
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| Localization of the gene encoding human BiP/GRP78, the endoplasmic reticulum cognate of the HSP70 family, to chromosome 9q34.
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| Biogenesis of MHC class I antigens: involvement of multiple chaperone molecules.
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| 91 | HSPA5
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| Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP.
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| cDNA cloning of the immunoglobulin heavy chain binding protein.
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| 93 | HSPA5, HSPA5P
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