1 | APMAP, HSPA1A, M6PR
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| The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease.
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| Gerber H, Mosser S, Boury-Jamot B, Stumpe M, Piersigilli A, Goepfert C, Dengjel J, Albrecht U, Magara F, Fraering PC.
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| Acta Neuropathol Commun. Jan 31;7(1):13. doi: 10.1186/s40478-019-0660-3. 2019
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2 | CLEC14A, HSPA1A
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| CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis.
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| Jang J, Kim MR, Kim TK, Lee WR, Kim JH, Heo K, Lee S.
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| Sci Rep 7(1):10666. doi: 10.1038/s41598-017-11118-y.
2017
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3 | HSPA1A, PRKN
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| HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle.
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| Drew BG, Ribas V, Le JA, Henstridge DC, Phun J, Zhou Z, Soleymani T, Daraei P, Sitz D, Vergnes L, Wanagat J, Reue K, Febbraio MA, Hevener AL.
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| Diabetes 63(5):1488-505. doi: 10.2337/db13-0665. Epub 2013 Dec 30. 2014
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4 | HSPA1A, WASF3
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| HSP90 and HSP70 proteins are essential for stabilization and activation of WASF3 metastasis-promoting protein.
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| Teng Y, Ngoka L, Mei Y, Lesoon L, Cowell JK.
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| J Biol Chem 287(13):10051-9. doi: 10.1074/jbc.M111.335000. Epub 2012 Feb 7.
2012
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5 | ATP2A1, HSPA1A
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| Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.
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| Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS.
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| Nature 484(7394):394-8. doi: 10.1038/nature10980.
2012
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6 | HSPA1A
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| Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis.
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| Meng L, Hunt C, Yaglom JA, Gabai VL, Sherman MY.
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| Oncogene 30(25):2836-45. doi: 10.1038/onc.2011.5. Epub 2011 Feb 7.
2011
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7 | HSPA1A, HSPA2
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| Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study.
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| Scieglinska D, Piglowski W, Chekan M, Mazurek A, Krawczyk Z.
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| Histochem Cell Biol 135(4):337-50. Epub 2011 Mar 4. 2011
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8 | HSPA1A
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| Comparison of hemodynamic, biochemical and hematological parameters of healthy pregnant women in the third trimester of pregnancy and the active labor phase.
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| Rodríguez-Dennen F, Martínez-Ocańa J, Kawa-Karasik S, Villanueva-Egan L, Reyes-Paredes N, Flisser A, Olivo-Díaz A.
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| BMC Pregnancy Childbirth 11:33.
2011
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9 | HSPA1A
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| Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies.
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| Molvarec A, Tamási L, Losonczy G, Madách K, Prohászka Z, Rigó J Jr.
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| Cell Stress Chaperones 15(3):237-47. Epub 2009 Oct 12. Review.
2010
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10 | ERN1, HSPA1A
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| HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.
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| Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A.
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| PLoS Biol 8(7):e1000410.
2010
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11 | FOXA1, HSPA1A
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| Up-regulation of the HSP72 by Foxa1 in MCF-7 human breast cancer cell line.
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| Song L, Xu Z, Zhang C, Qiao X, Huang C.
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| Biochem Biophys Res Commun 386(1):30-4. Epub 2009 May 30.
2009
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12 | HSPA1A, PGLYRP1, S100A4
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| Opposite roles of metastasin (S100A4) in two potentially tumoricidal mechanisms involving human lymphocyte protein Tag7 and Hsp70.
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| Dukhanina EA, Kabanova OD, Lukyanova TI, Shatalov YV, Yashin DV, Romanova EA, Gnuchev NV, Galkin AV, Georgiev GP, Sashchenko LP.
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| Proc Natl Acad Sci U S A 106(33):13963-7. Epub 2009 Aug 3.
2009
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13 | HSPA1A
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| Functional SNPs in HSPA1A gene predict risk of coronary heart disease.
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| He M, Guo H, Yang X, Zhang X, Zhou L, Cheng L, Zeng H, Hu FB, Tanguay RM, Wu T.
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| PLoS One 4(3):e4851. Epub 2009 Mar 31.
2009
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14 | HSPA1A, HSPBP1
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| Extracellular HspBP1 and Hsp72 synergistically activate epidermal growth factor receptor.
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| Evdonin A, Kinev A, Tsupkina N, Guerriero V, Raynes DA, Medvedeva N.
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| Biol Cell 101(6):351-60. doi: 10.1042/BC20080069.
2009
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15 | HSPA1A
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| HSP72 protects against obesity-induced insulin resistance.
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| Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA.
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| Proc Natl Acad Sci U S A 105(5):1739-44. Epub 2008 Jan 25. 2008
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16 | HSPA1A
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| Polymorphic analysis of the heat-shock protein 70 gene (HSPA1A) in Méničre's disease.
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| Kawaguchi S, Hagiwara A, Suzuki M.
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| Acta Otolaryngol 128(11):1173-7.
2008
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17 | HSPA1A, HSPA4, GATA1, CASP3
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| Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1.
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| Ribeil JA, Zermati Y, Vandekerckhove J, Cathelin S, Kersual J, Dussiot M, Coulon S, Moura IC, Zeuner A, Kirkegaard-Sorensen T, Varet B, Solary E, Garrido C, Hermine O.
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| Nature 445(7123):102-5. Epub 2006 Dec 10. 2007
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18 | HSPA14, HSPA1A, HSPA1B, HSPA2, HSPA3, HSPA4, HSPA7
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| The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.
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| Daugaard M, Rohde M, Jaatela M.
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| FEBS Lett 581(19):3702-10. Epub 2007 May 25. Review. 2007
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19 | HSPA1A
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| Quercetin suppresses heat shock-induced nuclear translocation of Hsp72.
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| Jakubowicz-Gil J, Pawlikowska-Pawlega B, Piersiak T, Pawelec J, Gawron A.
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| Folia Histochem Cytobiol 43(3):123-8. 2005
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20 | HSPA1A
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| Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.
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| Clemons NJ, Buzzard K, Steel R, Anderson RL.
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| J Biol Chem 280(10):9005-12. Epub 2005 Jan 4. 2005
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21 | HSPA1A
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| Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.
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| Stankiewicz AR, Lachapelle G, Foo CP, Radicioni SM, Mosser DD.
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| J Biol Chem 280(46):38729-39. Epub 2005 Sep 19. 2005
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22 | HSPA1A
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| IL-6 activates HSP72 gene expression in human skeletal muscle.
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| Febbraio MA, Steensberg A, Fischer CP, Keller C, Hiscock N, Pedersen BK.
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| Biochem Biophys Res Commun 296(5):1264-6. 2002
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23 | HSPA1A, SOX9
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| Identification of an interaction between SOX9 and HSP70.
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| Marshall OJ, Harley VR.
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| FEBS Lett 496(2-3):75-80. 2001
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24 | HSPA1A
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| An additional exon of stress-inducible heat shock protein 70 gene (HSP70-1).
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| Shimizu S, et al.
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| Biochem Biophys Res Commun 257(1):193-8. 1999
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25 | HSPA1A, HSPA1B, HSPA1L
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| Polymorphic analysis of the three MHC-linked HSP70 genes.
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| Milner CM, Campbell RD.
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| Immunogenetics 36(6):357-62. 1992
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26 | HSPA1A
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| Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease.
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| Ratanachaiyavong S, et al.
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| Clin Exp Immunol 84 : 48-52. 1991
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27 | HSPA1A, HSPA1B
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| Human major histocompatibility complex contains genes for the major heat shock protein HSP70.
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| Sargent CA, Dunham I, Trowsdale J, Campbell RD.
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| Proc Natl Acad Sci U S A 86(6):1968-72. 1989
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28 | HSPA1A, HSPA2, HSPA3, HSPA1B, HSPA1L
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| Chromosomal location of human genes encoding major heat-shock protein HSP70.
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| Harrison GS, Drabkin HA, Kao FT, Hartz J, Hart IM, Chu EH, Wu BJ, Morimoto RI.
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| Somat Cell Mol Genet 13(2):119-30. 1987
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29 | HSPA1A
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| Localization of a human heat-shock HSP 70 gene sequence to chromosome 6 and detection of two other loci by somatic-cell hybrid and restriction fragment length polymorphism analysis.
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| Goate AM, et al.
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| Hum Genet 75 : 123-128. 1987
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30 | HSPA1A, HSPA2, HSPA3, HSPAP1
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| A human gene family with sequence homology to Drosophila melanogaster Hsp70 heat shock genes.
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| Mues GI, Munn TZ, Raese JD.
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| J Biol Chem 261(2):874-7. 1986
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