| 1 | HMU1, HR
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| Marie Unna hereditary hypotrichosis accompanied by multiple familial trichoepithelioma in a Chinese family.
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| Huang Y, Cai C, Ren L, Cui C, Zhang X, Liu W.
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| J Dermatol 46(5):413-417. doi: 10.1111/1346-8138.14811. Epub 2019 Feb 27.
2019
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| 2 | APL, HR
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| Disease causing homozygous variants in the human hairless gene.
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| Mehmood S, Jan A, Raza SI, Ahmad F, Younus M, Irfanullah, Shahi S, Ayub M, Khan S, Ahmad W.
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| Int J Dermatol nt J Dermatol. 2015 Dec 18. doi: 10.1111/ijd.13109. [Epub ahead of print]
2015
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| 3 | HR
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| Hairless is a histone H3K9 demethylase.
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| Liu L, Kim H, Casta A, Kobayashi Y, Shapiro LS, Christiano AM.
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| FASEB J 28(4):1534-42. doi: 10.1096/fj.13-237677. Epub 2013 Dec 13.
2014
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| 4 | DKKL1, HR, SOSTDC1, VDR
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| Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes.
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| Hsieh JC, Estess RC, Kaneko I, Whitfield GK, Jurutka PW, Haussler MR.
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| J Endocrinol 220(2):165-78. doi: 10.1530/JOE-13-0212. Print 2014 Feb.
2014
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| 5 | HR
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| Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.
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| Luke CT, Casta A, Kim H, Christiano AM.
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| Exp Dermatol 22(10):644-9. doi: 10.1111/exd.12228.
2013
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| 6 | HR, MSX2
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| Hairless down-regulates expression of Msx2 and its related target genes in hair follicles.
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| Kim BK, Yoon SK.
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| J Dermatol Sci 71(3):203-9. doi: 10.1016/j.jdermsci.2013.04.019. Epub 2013 Apr 28.
2013
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| 7 | HR, PPARG
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| Hairless promotes PPARγ expression and is required for white adipogenesis.
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| Kumpf S, Mihlan M, Goginashvili A, Grandl G, Gehart H, Godel A, Schmidt J, Müller J, Bezzi M, Ittner A, Guccione E, Wolfrum C, Ricci R.
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| EMBO Rep 13(11):1012-20. doi: 10.1038/embor.2012.133. Epub 2012 Sep 11.
2012
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| 8 | DKKL1, DLX3, HR, SFRP1, SFRP2, SOSTDC1
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| Hairless plays a role in formation of inner root sheath via regulation of Dlx3 gene.
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| Kim BK, Lee HY, Choi JH, Kim JK, Yoon JB, Yoon SK.
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| J Biol Chem 287(20):16681-8. doi: 10.1074/jbc.M111.320770. Epub 2012 Mar 22.
2012
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| 9 | HR
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| Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle.
|
| Abbasi AA.
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| Sci Rep 1:32. doi: 10.1038/srep00032. Epub 2011 Jul 6.
2011
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| 10 | HR, VDR
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| Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function.
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| Mi Y, Zhang Y, Shen YF.
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| Biochim Biophys Acta 1812(12):1675-80. doi: 10.1016/j.bbadis.2011.09.015. Epub 2011 Sep 29.
2011
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| 11 | HMU1, HR
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| Overexpression of Hr links excessive induction of Wnt signaling to Marie Unna hereditary hypotrichosis.
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| Kim JK, Kim E, Baek IC, Kim BK, Cho AR, Kim TY, Song CW, Seong JK, Yoon JB, Stenn KS, Parimoo S, Yoon SK.
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| Hum Mol Genet 19(3):445-53. Epub 2009 Nov 6. 2010
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| 12 | HMU1, HR
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| Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis.
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| Wen Y, Liu Y, Xu Y, Zhao Y, Hua R, Wang K, Sun M, Li Y, Yang S, Zhang XJ, Kruse R, Cichon S, Betz RC, Nöthen MM, van Steensel MA, van Geel M, Steijlen PM, Hohl D, Huber M, Dunnill GS, Kennedy C, Messenger A, Munro CS, Terrinoni A, Hovnanian A, Bodemer C, de Prost Y, Paller AS, Irvine AD, Sinclair R, Green J, Shang D, Liu Q, Luo Y, Jiang L, Chen HD, Lo WH, McLean WH, He CD, Zhang X.
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| Nat Genet 41(2):228-33. Epub 2009 Jan 4.
2009
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| 13 | APL, HR
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| Atrichia with papular lesions: a report of three novel human hairless gene mutations and a revision of diagnostic criteria.
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| Yip L, Horev L, Sinclair R, Zlotogorski A.
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| Acta Derm Venereol 88(4):346-9.PMID: 18709303 2008
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| 14 | APL, HR
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| Identification of mutations in the human hairless gene in two new families with congenital atrichia.
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| Betz RC, Indelman M, Pforr J, Schreiner F, Bauer R, Bergman R, Lentze MJ, Nöthen MM, Cichon S, Sprecher E.
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| Arch Dermatol Res 299(3):157-61. Epub 2007 Mar 20.
2007
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| 15 | APL, HR
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| The alopecias associated with vitamin D-dependent rickets type IIA and with hairless gene mutations: a comparative clinical, histologic, and immunohistochemical study.
|
| Bergman R, Schein-Goldshmid R, Hochberg Z, Ben-Izhak O, Sprecher E.
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| Arch Dermatol 141(3):343-51. 2005
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| 16 | ATRX, DNMT3B, EMD, FSHMD1A, HR,LBR, LMNA, MECP2, NSD1, SMARCAL1
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| Perturbations of chromatin structure in human genetic disease: recent advances.
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| Bickmore WA, Van Der Maarel SM.
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| Hum Mol Genet 12 Suppl 2:R207-13. Epub 2003 Aug 05. 2003
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| 17 | ALUNC, HR
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| The hairless gene in androgenetic alopecia: results of a systematic mutation screening and a family-based association approach.
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| Hillmer AM, Kruse R, Macciardi F, Heyn U, Betz RC, Ruzicka T, Propping P, Nothen MM, Cichon S.
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| Br J Dermatol 146(4):601-8. 2002
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| 18 | ALUNC, HR
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| Genomic Organization of the Human Hairless Gene (HR) and Identification of a Mutation Underlying Congenital Atrichia in an Arab Palestinian Family.
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| Ahmad W, et al.
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| Genomics 56(2):141-148. 1999
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| 19 | APL, HR
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| Identification of a genetic defect in the hairless gene in atrichia with papular lesions: evidence for phenotypic heterogeneity among inherited atrichias.
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| Sprecher E, et al.
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| Am J Hum Genet 64(5):1323-9. 1999
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| 20 | APL, HR
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| Novel Hairless mutations in two kindreds with autosomal recessive papular atrichia.
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| Kruse R, Cichon S, Anker M, Hillmer AM, Barros-Nunez P, Cantu JM, Leal E, Weinlich G, Schmuth M, Fritsch P, Ruzicka T, Propping P, Nothen MM.
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| J Invest Dermatol 113(6):954-9. 1999
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| 21 | APL, ALUNC, HR
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| Alopecia universalis associated with a mutation in the human hairless gene.
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| Ahmad W, Faiyaz ul Haque M, Brancolini V, Tsou HC, ul Haque S, Lam H, Aita VM, Owen J, deBlaquiere M, Frank J, Cserhalmi-Friedman PB, Leask A, McGrath JA, Peacocke M, Ahmad M, Ott J, Christiano AM.
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| Science 279(5351):720-4. 1998
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| 22 | ALUNC, HR
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| Cloning, genomic organization, alternative transcripts and mutational anlysis of the gene responsible for autosomal recessive universal congenital alopecia.
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| Cichon S, et al.
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| Hum Mol Genet 7 : 1671-1679. 1998
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| 23 | ALUNC, HR
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| A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers.
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| Ahmad W, et al.
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| Am J Hum Genet 63 : 984-991. 1998
|