| 1 | HOXA9, MSI2, SYNCRIP
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| Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
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| Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gönen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Järås M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG.
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| Nat Genet 49(6):866-875. doi: 10.1038/ng.3854. Epub 2017 Apr 24.
2017
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| 2 | CDX4, HOXA10, HOXA9
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| Regulation of CDX4 gene transcription by HoxA9, HoxA10, the Mll-Ell oncogene and Shp2 during leukemogenesis.
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| Bei L, Shah C, Wang H, Huang W, Platanias LC, Eklund EA.
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| Oncogenesis 3:e135. doi: 10.1038/oncsis.2014.49.
2014
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| 3 | FLT3, HOXA9
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| Hoxa9 and Flt3 signaling synergistically regulate an early checkpoint in lymphopoiesis.
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| Gwin KA, Shapiro MB, Dolence JJ, Huang ZL, Medina KL.
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| J Immunol 191(2):745-54. doi: 10.4049/jimmunol.1203294. Epub 2013 Jun 14.
2013
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| 4 | HOXA9, PRMT5, SELE
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| HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules.
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| Bandyopadhyay S, Harris DP, Adams GN, Lause GE, McHugh A, Tillmaand EG, Money A, Willard B, Fox PL, Dicorleto PE.
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| Mol Cell Biol 32(7):1202-13. doi: 10.1128/MCB.05977-11. Epub 2012 Jan 23. 2012
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| 5 | CEBPA, DACH1, GATA1, GATA1, HOXA9, PBX2
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| Regulation of HOXA9 activity by predominant expression of DACH1 against C/EBPα and GATA-1 in myeloid leukemia with MLL-AF9.
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| Lee JW, Kim HS, Hwang J, Kim YH, Lim GY, Sohn WJ, Yoon SR, Kim JY, Park TS, Oh SH, Park KM, Choi SU, Ryoo ZY, Lee S.
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| Biochem Biophys Res Commun 426(3):299-305. doi: 10.1016/j.bbrc.2012.08.048.
2012
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| 6 | HOXA9, HOXB9, HOXC9, HOXD9
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| Axial Hox9 activity establishes the posterior field in the developing forelimb.
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| Xu B, Wellik DM.
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| Proc Natl Acad Sci U S A 108(12):4888-91. Epub 2011 Mar 7.
2011
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| 7 | HOXA10, HOXA9, MEIS1
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| Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
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| Orlovsky K, Kalinkovich A, Rozovskaia T, Shezen E, Itkin T, Alder H, Ozer HG, Carramusa L, Avigdor A, Volinia S, Buchberg A, Mazo A, Kollet O, Largman C, Croce CM, Nakamura T, Lapidot T, Canaani E.
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| Proc Natl Acad Sci U S A 108(19):7956-61. Epub 2011 Apr 25.
2011
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| 8 | HOXA10, HOXA9, ID2
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| Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines.
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| Nagel S, Venturini L, Marquez VE, Meyer C, Kaufmann M, Scherr M, MacLeod RA, Drexler HG.
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| Mol Cancer 9:151.
2010
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| 9 | CREB1, HOXA9, MEIS1
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| HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis.
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| Hu YL, Fong S, Ferrell C, Largman C, Shen WF.
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| Mol Cell Biol 29(18):5181-92. Epub 2009 Jul 20.
2009
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| 10 | HOXA9
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| HOXA9 is required for survival in human MLL-rearranged acute leukemias.
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| Faber J, Krivtsov AV, Stubbs MC, Wright R, Davis TN, van den Heuvel-Eibrink M, Zwaan CM, Kung AL, Armstrong SA.
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| Blood 113(11):2375-85. Epub 2008 Dec 3.PMID: 19056693 2009
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| 11 | NFKB1, HOXA9
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| Differential regulation of HOXA9 expression by nuclear factor kappa B (NF-kappaB) and HOXA9.
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| Trivedi CM, Patel RC, Patel CV.
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| Gene 408(1-2):187-95. Epub 2007 Nov 13. 2008
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| 12 | HOXA9
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| MicroRNA-126 regulates HOXA9 by binding to the homeobox.
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| Shen WF, Hu YL, Uttarwar L, Passegue E, Largman C.
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| Mol Cell Biol 28(14):4609-19. Epub 2008 May 12.PMID: 18474618 2008
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| 13 | HOXA9, IGF1R
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| HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia.
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| Whelan JT, Ludwig DL, Bertrand FE.
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| Leukemia 22(6):1161-9. Epub 2008 Mar 13.PMID: 18337761 2008
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| 14 | HOXA9
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| Transcriptional complexity of the HOXA9 locus.
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| Popovic R, Erfurth F, Zeleznik-Le N.
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| Blood Cells Mol Dis 40(2):156-9. Epub 2007 Oct 3. Review.PMID: 17916434 2008
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| 15 | HOXA9, NUP98
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| Additional acquisition of t(1;21)(p32;q22) in a patient relapsing with acute myelogenous leukemia with NUP98-HOXA9.
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| Aoki T, Miyamoto T, Yoshida S, Yamamoto A, Yamauchi T, Yoshimoto G, Mori Y, Kamezaki K, Iwasaki H, Takenaka K, Harada N, Nagafuji K, Teshima T, Akashi K.
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| Int J Hematol 88(5):571-4. Epub 2008 Nov 13.PMID: 19005624 2008
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| 16 | CRABP1, HOXA9, HOXB5, SCGB3A1
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| DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets.
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| Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE.
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| Mol Cancer 6:45.PMID: 17623056 2007
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| 17 | HOXA9, PIM1
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| Evidence that the Pim1 kinase gene is a direct target of HOXA9.
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| Hu YL, Passegué E, Fong S, Largman C, Lawrence HJ.
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| Blood 109(11):4732-8. Epub 2007 Feb 27.PMID: 17327400 2007
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| 18 | HOXA9, SELE
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| HOXA9 participates in the transcriptional activation of E-selectin in endothelial cells.
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| Bandyopadhyay S, Ashraf MZ, Daher P, Howe PH, DiCorleto PE.
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| Mol Cell Biol 27(12):4207-16. Epub 2007 Apr 23.PMID: 17452460 2007
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| 19 | PICALM, MLLT10, HOXA9
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| Acute monocytic leukemia with coexpression of minor BCR-ABL1 and PICALM-MLLT10 fusion genes along with overexpression of HOXA9.
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| Sindt A, Deau B, Brahim W, Staal A, Visanica S, Villarese P, Rault JP, Macintyre E, Delabesse E.
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| Genes Chromosomes Cancer 45(6):575-82. 2006
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| 20 | CDX4, HOXA9
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| Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells.
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| Yan J, Chen YX, Desmond A, Silva A, Yang Y, Wang H, Hua X.
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| PLoS One 1:e47.
2006
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| 21 | NUP98, MEIS1, HOXA9, CYBB
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| HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation.
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| Bei L, Lu Y, Eklund EA.
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| J Biol Chem 280(13):12359-70. Epub 2005 Jan 28. 2005
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| 22 | HOXA9
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| HOXA9 expression increases with age in human haemopoietic cells.
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| Morgan R, Begum R, Theti D, Chansa M, Pettengell R, Sohal J.
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| Leuk Res 29(10):1221-2. Epub 2005 Apr 9. 2005
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| 23 | HOXA9
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| Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation.
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| Vijapurkar U, Fischbach N, Shen W, Brandts C, Stokoe D, Lawrence HJ, Largman C.
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| Mol Cell Biol 24(9):3827-37.PMID: 15082777 2004
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| 24 | HOXA9
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| A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis.
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| Dintilhac A, Bihan R, Guerrier D, Deschamps S, Pellerin I.
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| Gene Expr Patterns. 4(2):215-22. 2004
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| 25 | HOXA9
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| CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein.
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| Zhang Y, Morrone G, Zhang J, Chen X, Lu X, Ma L, Moore M, Zhou P.
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| EMBO J. 22(22):6057-67. 2003
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| 26 | MEIS1, HOXA9
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| Frequent co-expression of HoxA9 and Meis1 genes in infant acute lymphoblastic leukaemia with MLL rearrangement.
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| Imamura T, Morimoto A, Takanashi M, Hibi S, Sugimoto T, Ishii E, Imashuku S.
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| Br J Haematol 119(1):119-21. 2002
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| 27 | HOXA9
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| Hoxa-9 represses transforming growth factor-beta-induced osteopontin gene transcription.
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| Shi X, Bai S, Li L, Cao X.
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| J Biol Chem 276(1):850-5. 2001
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| 28 | AMLT2, HOXA9, NUP98
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| Low frequency of rearrangements of the homeobox gene HOXA9/t(7;11) in adult acute myeloid leukemia.
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| Kwong YL, et al.
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| Genes Chromosomes Cancer 25(1):70-4. 1999
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| 29 | HOXA9, MEIS1
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| Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias.
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| Lawrence HJ, Rozenfeld S, Cruz C, Matsukuma K, Kwong A, Komuves L, Buchberg AM, Largman C.
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| Leukemia 13(12):1993-9. 1999
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| 30 | HOXA9
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| HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.
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| Shen WF, Rozenfeld S, Kwong A, Köm ves LG, Lawrence HJ, Largman C.
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| Mol Cell Biol. 19(4):3051-61. 1999
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| 31 | HOXA9
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| Genomic structure and sequence analysis of human HOXA-9.
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| Kim MH, et al.
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| DNA Cell Biol 17 : 407-414. 1998
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| 32 | AMLT2, HOXA9, NUP98
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| Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.
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| Nakamura T, et al.
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| Nat Genet 12 : 154-158. 1996
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| 33 | AMLT2, HOXA9, NUP98
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| The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9.
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| Borrow J, et al.
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| Nat Genet 12 : 159-167. 1996
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