| 1 | HERC2, HIF1AN, MAPK6, NEURL4, UBE3A
|
| Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.
|
| Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM.
|
| Mol Cell Biol 32(15):3095-106. Epub 2012 May 29. 2012
|
| 2 | HIF1AN
|
| The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis.
|
| Pelletier J, Dayan F, Durivault J, Ilc K, Pécou E, Pouysségur J, Mazure NM.
|
| Oncogene 31(24):2989-3001. doi: 10.1038/onc.2011.471. Epub 2011 Oct 17.
2012
|
| 3 | HIF1AN, JMJD6, KDM8
|
| Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.
|
| Del Rizzo PA, Krishnan S, Trievel RC.
|
| Mol Cell Biol 32(19):4044-52. doi: 10.1128/MCB.00513-12. Epub 2012 Jul 30.
2012
|
| 4 | HIF1AN
|
| Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression.
|
| Hyseni A, van der Groep P, van der Wall E, van Diest PJ.
|
| Cell Oncol (Dordr) 34(6):565-70. doi: 10.1007/s13402-011-0053-5. Epub 2011 Jul 6.
2011
|
| 5 | BAX, HIF1AN
|
| Prevention of apoptosis by the interaction between FIH1 and Bax.
|
| Yan B, Kong M, Chen YH.
|
| Mol Cell Biochem 348(1-2):1-9. Epub 2010 Nov 11.
2011
|
| 6 | APBA3, HIF1AN
|
| Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1.
|
| Sakamoto T, Seiki M.
|
| J Biol Chem 284(44):30350-9. Epub 2009 Sep 2. 2009
|
| 7 | HIF1AN
|
| Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
|
| Wilkins SE, Hyvärinen J, Chicher J, Gorman JJ, Peet DJ, Bilton RL, Koivunen P.
|
| Int J Biochem Cell Biol 41(7):1563-71. Epub 2009 Jan 20.
2009
|
| 8 | HIF1AN
|
| Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.
|
| Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, Ericson J, Peet DJ, Lendahl U, Poellinger L.
|
| Proc Natl Acad Sci U S A 105(9):3368-73. Epub 2008 Feb 25.
2008
|
| 9 | HIF1AN, SIAH1
|
| Abundance of aspargynyl-hydroxylase FIH is regulated by Siah-1 under normoxic conditions.
|
| Fukuba H, Takahashi T, Jin HG, Kohriyama T, Matsumoto M.
|
| Neurosci Lett 433(3):209-14. Epub 2008 Jan 20.
2008
|
| 10 | HIF1A, HIF1AN
|
| Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity.
|
| Walmsley SR, Print C, Farahi N, Peyssonnaux C, Johnson RS, Cramer T, Sobolewski A, Condliffe AM, Cowburn AS, Johnson N, Chilvers ER.
|
| J Exp Med 201(1):105-15.
2005
|
| 11 | HIF1AN
|
| FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
|
| Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK.
|
| Genes Dev 16(12):1466-71. 2002
|
| 12 | HIF1A, HIF1AN
|
| Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
|
| Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ.
|
| J Biol Chem 277(29):26351-5. Epub 2002 May 31. 2002
|
| 13 | HIF1AN
|
| FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediaterepression of HIF-1 transcriptional activity.
|
| Mahon PC, Hirota K, Semenza GL.
|
| Genes Dev 15(20):2675-86. 2001
|