| 1 | HHIP
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| The hedgehog antagonist HHIP as a favorable prognosticator in glioblastoma.
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| Chang L, Zhang P, Zhao D, Liu H, Wang Q, Li C, Du W, Liu X, Zhang H, Zhang Z, Jiang C.
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| Tumour Biol 37(3):3979-86. doi: 10.1007/s13277-015-3442-y. Epub 2015 Oct 19.
2016
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| 2 | HHIP
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| Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function.
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| Holtz AM, Griffiths SC, Davis SJ, Bishop B, Siebold C, Allen BL.
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| J Cell Biol 209(5):739-57. doi: 10.1083/jcb.201411024.
2015
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| 3 | HHIP
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| Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling.
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| Kwong L, Bijlsma MF, Roelink H.
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| Nat Commun 5:4849. doi: 10.1038/ncomms5849.
2014
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| 4 | HHIP, PTCH1, PTCH2
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| Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
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| Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL.
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| Development 140(16):3423-34. doi: 10.1242/dev.095083.
2013
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| 5 | HHIP
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| Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.
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| Kim WJ, Oh YM, Lee JH, Park CS, Park SW, Park JS, Lee SD.
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| Respirology 18(8):1202-9. doi: 10.1111/resp.12139.
2013
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| 6 | HHIP, SHH
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| Single-nucleotide variants in two Hedgehog genes, SHH and HHIP, as genetic cause of combined pituitary hormone deficiency.
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| Gorbenko del Blanco D, de Graaff LC, Visser TJ, Hokken-Koelega AC.
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| Clin Endocrinol (Oxf) 78(3):415-23. doi: 10.1111/cen.12000.
2013
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| 7 | HHIP
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| Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP.
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| Zhou X, Baron RM, Hardin M, Cho MH, Zielinski J, Hawrylkiewicz I, Sliwinski P, Hersh CP, Mancini JD, Lu K, Thibault D, Donahue AL, Klanderman BJ, Rosner B, Raby BA, Lu Q, Geldart AM, Layne MD, Perrella MA, Weiss ST, Choi AM, Silverman EK.
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| Hum Mol Genet 21(6):1325-35. doi: 10.1093/hmg/ddr569. Epub 2011 Dec 2.
2012
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| 8 | HHIP
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| Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples.
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| Shahi MH, Afzal M, Sinha S, Eberhart CG, Rey JA, Fan X, Castresana JS.
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| J Neurooncol 103(2):287-96. doi: 10.1007/s11060-010-0401-8. Epub 2010 Sep 19.
2011
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| 9 | HHIP
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| Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.
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| Bishop B, Aricescu AR, Harlos K, O'Callaghan CA, Jones EY, Siebold C.
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| Nat Struct Mol Biol 16(7):698-703. doi: 10.1038/nsmb.1607. Epub 2009 Jun 28.
2009
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| 10 | HHIP
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| The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
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| Bosanac I, Maun HR, Scales SJ, Wen X, Lingel A, Bazan JF, de Sauvage FJ, Hymowitz SG, Lazarus RA.
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| Nat Struct Mol Biol 16(7):691-7. doi: 10.1038/nsmb.1632. Epub 2009 Jun 28.
2009
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| 11 | HHIP, SMO
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| Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.
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| Ochi H, Pearson BJ, Chuang PT, Hammerschmidt M, Westerfield M.
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| Dev Biol 297(1):127-40. Epub 2006 May 6.
2006
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| 12 | BTRC, CREBBP, CSRP2, FKBP8, GAS1, GSK3B, HHAT, HHIP, IFT88, KIF27, KIF3A, KIF7, RAB23, SHH, STIL, STK36, SUFU, VTN
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| Hedgehog signaling and congenital malformations.
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| Nieuwenhuis E, Hui CC.
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| Clin Genet 67(3):193-208. 2005
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| 13 | RERE, TSPAN8, HHIP, CHI3L1
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| Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization.
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| Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW.
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| Hepatology 38(3):577-88. 2003
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| 14 | HHIP
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| The human hedgehog-interacting protein gene: structure and chromosome mapping to4q31.21-->q31.3.
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| Bak M, Hansen C, Friis Henriksen K, Tommerup N.
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| Cytogenet Cell Genet 92(3-4):300-3. 2001
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| 15 | HHIP
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| Hedgehog signaling in animal development: paradigms and principles.
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| Ingham PW, McMahon AP.
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| Genes Dev 15(23):3059-87. Review. No abstract available. 2001
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| 16 | HHIP
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| Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.
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| Chuang PT, McMahon AP.
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| Nature 397(6720):617-21. 1999
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