| 1 | CER1, HHEX, SOX17
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| Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells.
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| Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD.
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| Stem Cells 32(6):1515-26. doi: 10.1002/stem.1695.
2014
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| 2 | CD81, GPC3, HHEX
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| Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex.
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| Bhave VS, Mars W, Donthamsetty S, Zhang X, Tan L, Luo J, Bowen WC, Michalopoulos GK.
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| Am J Pathol 183(1):153-9. doi: 10.1016/j.ajpath.2013.03.013. Epub 2013 May 8.
2013
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| 3 | HHEX
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| A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.
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| Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM.
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| Dev Biol 351(2):297-310. Epub 2011 Jan 4.
2011
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| 4 | CDKAL1, HHEX
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| Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender.
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| Ryoo H, Woo J, Kim Y, Lee C.
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| Eur J Hum Genet 19(6):672-5. Epub 2011 Feb 2. 2011
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| 5 | HHEX, IRX3, SOX4
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| Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.
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| Ragvin A, Moro E, Fredman D, Navratilova P, Drivenes Ø, Engström PG, Alonso ME, Mustienes Ede L, Skarmeta JL, Tavares MJ, Casares F, Manzanares M, van Heyningen V, Molven A, Njølstad PR, Argenton F, Lenhard B, Becker TS.
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| Proc Natl Acad Sci U S A 107(2):775-80. Epub 2009 Dec 22.PMID: 20080751 2010
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| 6 | HHEX, SOX13
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| Interaction between Hhex and SOX13 modulates Wnt/TCF activity.
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| Marfil V, Moya M, Pierreux CE, Castell JV, Lemaigre FP, Real FX, Bort R.
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| J Biol Chem 285(8):5726-37. Epub 2009 Dec 22. 2010
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| 7 | HHEX
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| PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.
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| Noy P, Williams H, Sawasdichai A, Gaston K, Jayaraman PS.
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| Mol Cell Biol 30(9):2120-34. Epub 2010 Feb 22.PMID: 20176809 2010
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| 8 | HHEX, TLE1
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| The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors.
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| Desjobert C, Noy P, Swingler T, Williams H, Gaston K, Jayaraman PS.
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| Biochem J 417(1):121-32.
2009
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| 9 | HHEX
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| CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding.
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| Soufi A, Noy P, Buckle M, Sawasdichai A, Gaston K, Jayaraman PS.
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| Nucleic Acids Res 37(10):3288-300. Epub 2009 Mar 25.PMID: 19324893 2009
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| 10 | HHEX
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| Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies.
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| Ruchat SM, Elks CE, Loos RJ, Vohl MC, Weisnagel SJ, Rankinen T, Bouchard C, Pérusse L.
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| Acta Diabetol 46(3):217-26. Epub 2008 Dec 10.PMID: 1908252 2009
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| 11 | HHEX
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| HHEX gene polymorphisms are associated with type 2 diabetes in the Dutch Breda cohort.
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| van Vliet-Ostaptchouk JV, Onland-Moret NC, van Haeften TW, Franke L, Elbers CC, Shiri-Sverdlov R, van der Schouw YT, Hofker MH, Wijmenga C.
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| Eur J Hum Genet 16(5):652-6. Epub 2008 Jan 30. 2008
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| 12 | HHEX, SLC30A8, KIF11, IDE
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| A genome-wide association study identifies novel risk loci for type 2 diabetes.
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| Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P.
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| Nature 445(7130):881-5. Epub 2007 Feb 11. 2007
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| 13 | HHEX, IGFBP2, TCF7L2, CDKAL1, SLC30A8, KCNJ11
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| A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
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| Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li XY, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M.
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| Science 316(5829):1341-5. Epub 2007 Apr 26. 2007
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| 14 | HHEX
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| HEX expression and localization in normal mammary gland and breast carcinoma.
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| Puppin C, Puglisi F, Pellizzari L, Manfioletti G, Pestrin M, Pandolfi M, Piga A, Di Loreto C, Damante G.
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| BMC Cancer 6:192. 2006
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| 15 | HHEX
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| The homeobox gene Hex induces T-cell-derived lymphomas when overexpressed in hematopoietic precursor cells.
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| George A, Morse HC 3rd, Justice MJ.
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| Oncogene 22(43):6764-73. 2003
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| 16 | HHEX
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| Genomic organization and chromosome mapping of the human homeobox gene HHEX.
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| Morgutti M, Demori E, Pecile V, Amoroso A, Rustighi A, Manfioletti G.
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| Cytogenet Cell Genet 94(1-2):30-2. 2001
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| 17 | HHEX
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| A homology-based molecular model of the proline-rich homeodomain protein Prh, from haematopoietic cells.
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| Neidle S, Goodwin GH.
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| FEBS Lett 345(2-3):93-8. Review.PMID: 7911091 1994
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| 18 | HHEX
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| PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells.
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| Hromas R, et al.
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| Biochem Biophys Res Commun 195 : 976-983. 1993
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| 19 | HHEX
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| HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human.
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| Bedford FK, et al.
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| Nucleic Acids Res 21(5):1245-9. 1993
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