Citations for
1HES6
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease
Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C.
Cell Death Differ. Jun;28(6):1990-2000. doi: 10.1038/s41418-020-00730-7. Epub 2021 Jan 18. 2021
2HES6, PPARG
Hairy and enhancer of split 6 prevents hepatic lipid accumulation through inhibition of Pparg2 expression. 2017 PMID:
Park JE, Lee M, Kim SC, Zhang Y, Hardwick JP, Lee YK.
Hepatol Commun. Nov 8;1(10):1085-1098. doi: 10.1002/hep4.1120. 2017
3HES6
Hairy and Enhancer of Split 6 (Hes6) Deficiency in Mouse Impairs Neuroblast Differentiation in Dentate Gyrus Without Affecting Cell Proliferation and Integration into Mature Neurons
Nam SM, Kim YN, Kim JW, Kyeong DS, Lee SH, Son Y, Shin JH, Kim J, Yi SS, Yoon YS, Seong JK.
Cell Mol Neurobiol. 2016
4HES6
HES6 promotes prostate cancer aggressiveness independently of Notch signalling.
Carvalho FL, Marchionni L, Gupta A, Kummangal BA, Schaeffer EM, Ross AE, Berman DM.
J Cell Mol Med. Jul;19(7):1624-36. doi: 10.1111/jcmm.12537. Epub 2015 Apr 12. 2015
5HES6, HNF4A
All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade
Kim SC, Kim CK, Axe D, Cook A, Lee M, Li T, Smallwood N, Chiang JY, Hardwick JP, Moore DD, Lee YK.
Hepatology. May;59(5):1750-60. doi: 10.1002/hep.26699. Epub 2014 Mar 26. 2014
6HES6, NFKB1, RELA
Interaction and antagonistic roles of NF-κB and Hes6 in the regulation of cortical neurogenesis.
Methot L, Hermann R, Tang Y, Lo R, Al-Jehani H, Jhas S, Svoboda D, Slack RS, Barker PA, Stifani S.
Mol Cell Biol. Jul;33(14):2797-808. doi: 10.1128/MCB.01610-12. Epub 2013 May 20. 2013
7HES6
HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation.
Haapa-Paananen S, Kiviluoto S, Waltari M, Puputti M, Mpindi JP, Kohonen P, Tynninen O, Haapasalo H, Joensuu H, Perälä M, Kallioniemi O.
Oncogene 31(10):1299-310. doi: 10.1038/onc.2011.316. Epub 2011 Jul 25. 2012
8HES6
Hes6 is required for actin cytoskeletal organization in differentiating C2C12 myoblasts.
Malone CM, Domaschenz R, Amagase Y, Dunham I, Murai K, Jones PH.
Exp Cell Res 317(11):1590-602. doi: 10.1016/j.yexcr.2011.03.023. Epub 2011 Apr 9. 2011
9HES6
HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation.
Vilas-Boas F, Henrique D.
PLoS One 5(12):e15459. 2010
10HES6
Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation.
Hartman J, Lam EW, Gustafsson JA, Ström A.
Breast Cancer Res 11(6):R79. Epub 2009 Nov 5. 2009
11HES6
Hes6 controls cell proliferation via interaction with cAMP-response element-binding protein-binding protein in the promyelocytic leukemia nuclear body.
Eun B, Lee Y, Hong S, Kim J, Lee HW, Kim K, Sun W, Kim H.
J Biol Chem 283(9):5939-49. Epub 2007 Dec 26. 2008
12ATOH1, HES6
Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells.
Scheffer D, Sage C, Corey DP, Pingault V.
FEBS Lett 581(24):4651-6. Epub 2007 Sep 4. 2007
13HES6
HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F.
Biochem Biophys Res Commun 355(2):331-7. Epub 2007 Feb 5. 2007
14HES6
Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms.
Jhas S, Ciura S, Belanger-Jasmin S, Dong Z, Llamosas E, Theriault FM, Joachim K, Tang Y, Liu L, Liu J, Stifani S.
J Neurosci 26(43):11061-71. 2006
15HES1, HES6
Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms.
Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S.
Mol Cell Biol 23(19):6922-35. 2003
16HES6
The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.
Bae S, Bessho Y, Hojo M, Kageyama R.
Development 127(13):2933-43. 2000