Citations for
HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation.
Haapa-Paananen S, Kiviluoto S, Waltari M, Puputti M, Mpindi JP, Kohonen P, Tynninen O, Haapasalo H, Joensuu H, Perälä M, Kallioniemi O.
Oncogene 31(10):1299-310. doi: 10.1038/onc.2011.316. Epub 2011 Jul 25. 2012
Hes6 is required for actin cytoskeletal organization in differentiating C2C12 myoblasts.
Malone CM, Domaschenz R, Amagase Y, Dunham I, Murai K, Jones PH.
Exp Cell Res 317(11):1590-602. doi: 10.1016/j.yexcr.2011.03.023. Epub 2011 Apr 9. 2011
HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation.
Vilas-Boas F, Henrique D.
PLoS One 5(12):e15459. 2010
Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation.
Hartman J, Lam EW, Gustafsson JA, Ström A.
Breast Cancer Res 11(6):R79. Epub 2009 Nov 5. 2009
Hes6 controls cell proliferation via interaction with cAMP-response element-binding protein-binding protein in the promyelocytic leukemia nuclear body.
Eun B, Lee Y, Hong S, Kim J, Lee HW, Kim K, Sun W, Kim H.
J Biol Chem 283(9):5939-49. Epub 2007 Dec 26. 2008
Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells.
Scheffer D, Sage C, Corey DP, Pingault V.
FEBS Lett 581(24):4651-6. Epub 2007 Sep 4. 2007
HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.
Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F.
Biochem Biophys Res Commun 355(2):331-7. Epub 2007 Feb 5. 2007
Hes6 inhibits astrocyte differentiation and promotes neurogenesis through different mechanisms.
Jhas S, Ciura S, Belanger-Jasmin S, Dong Z, Llamosas E, Theriault FM, Joachim K, Tang Y, Liu L, Liu J, Stifani S.
J Neurosci 26(43):11061-71. 2006
Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms.
Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S.
Mol Cell Biol 23(19):6922-35. 2003
The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.
Bae S, Bessho Y, Hojo M, Kageyama R.
Development 127(13):2933-43. 2000