| 1 | CDLS, CDLS2, CDLS4, CDLS5, CDLSX, HDAC8, NIPBL, RAD21, SMC1A, SMC3
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| Impairment of Retinoic Acid Signaling in Cornelia de Lange Syndrome Fibroblasts.
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| Fazio G, Bettini LR, Rigamonti S, Meta D, Biondi A, Cazzaniga G, Selicorni A, Massa V.
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| Birth Defects Res 109(16):1268-1276. doi: 10.1002/bdr2.1070. Epub 2017 Jul 28.
2017
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| 2 | FOSL2, HDAC8, SOX4
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| SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 in adult T-cell leukemia/lymphoma.
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| Higuchi T, Nakayama T, Arao T, Nishio K, Yoshie O.
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| Blood 121(18):3640-9. doi: 10.1182/blood-2012-07-441022. Epub 2013 Mar 12.
2013
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| 3 | HDAC8
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| HDAC8 substrates: Histones and beyond.
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| Wolfson NA, Ann Pitcairn C, Fierke CA.
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| Biopolymers 99(2):112-26. doi: 10.1002/bip.22135.
2013
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| 4 | HDAC8
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| Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.
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| Gao SM, Chen CQ, Wang LY, Hong LL, Wu JB, Dong PH, Yu FJ.
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| Exp Hematol 41(3):261-70.e4. doi: 10.1016/j.exphem.2012.10.012. Epub 2012 Oct 27.
2013
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| 5 | HDAC8
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| Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8.
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| Yan W, Liu S, Xu E, Zhang J, Zhang Y, Chen X, Chen X.
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| Oncogene 32(5):599-609. doi: 10.1038/onc.2012.81. Epub 2012 Mar 5.
2013
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| 6 | CDLS5, HDAC8
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| HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
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| Deardorff MA, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato N, Ernst S, Francey LJ, Gyftodimou Y, Hirashima K, Hullings M, Ishikawa Y, Jaulin C, Kaur M, Kiyono T, Lombardi PM, Magnaghi-Jaulin L, Mortier GR, Nozaki N, Petersen MB, Seimiya H, Siu VM, Suzuki Y, Takagaki K, Wilde JJ, Willems PJ, Prigent C, Gillessen-Kaesbach G, Christianson DW, Kaiser FJ, Jackson LG, Hirota T, Krantz ID, Shirahige K.
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| Nature 489(7415):313-7. doi: 10.1038/nature11316.
2012
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| 7 | HDAC8
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| Insights from comprehensive multiple receptor docking to HDAC8.
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| Brunsteiner M, Petukhov PA.
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| J Mol Model 18(8):3927-39. doi: 10.1007/s00894-011-1297-8. Epub 2012 Mar 20.
2012
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| 8 | HDAC8, WTSL1
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| X-exome sequencing identifies a HDAC8 variant in a large pedigree with X-linked intellectual disability, truncal obesity, gynaecomastia, hypogonadism and unusual face.
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| Harakalova M, van den Boogaard MJ, Sinke R, van Lieshout S, van Tuil MC, Duran K, Renkens I, Terhal PA, de Kovel C, Nijman IJ, van Haelst M, Knoers NV, van Haaften G, Kloosterman W, Hennekam RC, Cuppen E, Ploos van Amstel HK.
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| J Med Genet 49(8):539-43. doi: 10.1136/jmedgenet-2012-100921. 2012
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| 9 | CDLS5, HDAC8
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| X-exome sequencing identifies a HDAC8 variant in a large pedigree with X-linked intellectual disability, truncal obesity, gynaecomastia, hypogonadism and unusual face.
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| Harakalova M, van den Boogaard MJ, Sinke R, van Lieshout S, van Tuil MC, Duran K, Renkens I, Terhal PA, de Kovel C, Nijman IJ, van Haelst M, Knoers NV, van Haaften G, Kloosterman W, Hennekam RC, Cuppen E, Ploos van Amstel HK.
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| J Med Genet 49(8):539-43. doi: 10.1136/jmedgenet-2012-100921.
2012
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| 10 | HDAC8
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| Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.
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| Yamauchi Y, Boukari H, Banerjee I, Sbalzarini IF, Horvath P, Helenius A.
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| PLoS Pathog 7(10):e1002316. doi: 10.1371/journal.ppat.1002316. Epub 2011 Oct 27.
2011
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| 11 | HDAC8
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| Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function .
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| Dowling DP, Gattis SG, Fierke CA, Christianson DW.
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| Biochemistry 49(24):5048-56.
2010
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| 12 | HDAC8
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| Activation and inhibition of histone deacetylase 8 by monovalent cations.
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| Gantt SL, Joseph CG, Fierke CA.
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| J Biol Chem 285(9):6036-43. doi: 10.1074/jbc.M109.033399. Epub 2009 Dec 22.
2010
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| 13 | HDAC8
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| Epigenetic control of skull morphogenesis by histone deacetylase 8.
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| Haberland M, Mokalled MH, Montgomery RL, Olson EN.
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| Genes Dev 23(14):1625-30. doi: 10.1101/gad.1809209.
2009
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| 14 | HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9
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| The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.
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| Yang XJ, Seto E.
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| Nat Rev Mol Cell Biol 9(3):206-18. Review.
2008
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| 15 | HDAC8
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| Expression profile of class I histone deacetylases in human cancer tissues.
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| Nakagawa M, Oda Y, Eguchi T, Aishima S, Yao T, Hosoi F, Basaki Y, Ono M, Kuwano M, Tanaka M, Tsuneyoshi M.
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| Oncol Rep 18(4):769-74.
2007
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| 16 | HDAC8
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| Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex.
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| Vannini A, Volpari C, Gallinari P, Jones P, Mattu M, Carfí A, De Francesco R, Steinkühler C, Di Marco S.
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| EMBO Rep 8(9):879-84. Epub 2007 Aug 10.
2007
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| 17 | HDAC8
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| Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.
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| Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V.
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| FASEB J 19(8):966-8. Epub 2005 Mar 16.
2005
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| 18 | HDAC8, PABPP1, PABPP2
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| Characterization of a highly complex region in Xq13 and mapping of three isodicentric breakpoints associated with preleukemia.
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| McDonell N, Ramser J, Francis F, Vinet MC, Rider S, Sudbrak R, Riesselman L, Yaspo ML, Reinhardt R, Monaco AP, Ross F, Kahn A, Kearney L, Buckle V, Chelly J.
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| Genomics 64(3):221-9. 2000
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| 19 | HDAC8
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| Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.
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| Hu E, Chen Z, Fredrickson T, Zhu Y, Kirkpatrick R, Zhang GF, Johanson K, Sung CM, Liu R, Winkler J.
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| J Biol Chem 275(20):15254-64. 2000
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| 20 | HDAC8
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| Cloning and characterization of human histone deacetylase 8.
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| Van den Wyngaert I, de Vries W, Kremer A, Neefs J, Verhasselt P, Luyten WH, Kass SU.
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| FEBS Lett 478(1-2):77-83. 2000
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| 21 | HDAC8
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| Cloning and characterization of a novel human histone deacetylase, HDAC8.
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| Buggy JJ, Sideris ML, Mak P, Lorimer DD, McIntosh B, Clark JM.
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| Biochem J 350 Pt 1:199-205. 2000
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