1 | HCRTR1, MRAP2, PROKR1
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| Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling.
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| Rouault AAJ, Lee AA, Sebag JA.
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| Biochim Biophys Acta Mol Cell Res. Dec;1864(12):2322-2329. doi: 10.1016/j.bbamcr.2017.09.008. Epub 2017 Sep 20 2017
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2 | HCRTR1
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| Hypocretin receptor 1 blockade produces bimodal modulation of cocaine-associated mesolimbic dopamine signaling.
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| Levy KA, Brodnik ZD, Shaw JK, Perrey DA, Zhang Y, Espaņa RA.
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| Psychopharmacology (Berl). Sep;234(18):2761-2776. doi: 10.1007/s00213-017-4673-y. Epub 2017 Jun 30 2017
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3 | HCRTR1
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| Functional inactivation of hypocretin 1 receptors in the medial prefrontal cortex affects the pyramidal neuron activity and gamma oscillations: An in vivo multiple-channel single-unit recording study.
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| He C, Chen QH, Ye JN, Li C, Yang L, Zhang J, Xia JX, Hu ZA.
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| Neuroscience Jun 25;297:1-10. doi: 10.1016/j.neuroscience.2015.03.044. Epub 2015 Mar 30 2015
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4 | HCRTR1, OPRK1
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| The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism.
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| Robinson JD, McDonald PH.
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| Cell Signal. Jul;27(7):1449-56. doi: 10.1016/j.cellsig.2015.03.026. Epub 2015 Apr 6 2015
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5 | HCRTR1
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| Orexin receptor-1 in the locus coeruleus plays an important role in cue-dependent fear memory consolidation.
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| Soya S, Shoji H, Hasegawa E, Hondo M, Miyakawa T, Yanagisawa M, Mieda M, Sakurai T.
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| J Neurosci. Sep 4;33(36):14549-57. doi: 10.1523/JNEUROSCI.1130-13.2013 2013
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6 | HCRTR1
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| Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.
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| Morairty SR, Revel FG, Malherbe P, Moreau JL, Valladao D, Wettstein JG, Kilduff TS, Borroni E.
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| PLoS One 7(7):e39131. doi: 10.1371/journal.pone.0039131. Epub 2012 Jul 2 2012
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7 | HCRTR1
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| OX1 orexin receptors couple to adenylyl cyclase regulation via multiple mechanisms.
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| Holmqvist T, Johansson L, Ostman M, Ammoun S, Akerman KE, Kukkonen JP.
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| J Biol Chem 280(8):6570-9. Epub 2004 Dec 16. 2005
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8 | HCRT, HCRTR1, HCRTR2
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| Orexins and orexin receptors : a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
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| Sakurai T, et al.
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| Cell 92 : 573-585. 1998
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