Citations for
1CREB3, HCFC1, NR3C1
LUMAN/CREB3 is a key regulator of glucocorticoid-mediated stress responses.
Penney J, Mendell A, Zeng M, Tran K, Lymer J, Turner PV, Choleris E, MacLusky N, Lu R.
Mol Cell Endocrinol 439:95-104. doi: 10.1016/j.mce.2016.10.022. 2017
2HCFC1
Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification.
Minocha S, Bessonnard S, Sung TL, Moret C, Constam DB, Herr W.
Dev Biol 418(1):75-88. doi: 10.1016/j.ydbio.2016.08.008. 2016
3HCFC1
Compensatory embryonic response to allele-specific inactivation of the murine X-linked gene Hcfc1.
Minocha S, Sung TL, Villeneuve D, Lammers F, Herr W.
Dev Biol 412(1):1-17. doi: 10.1016/j.ydbio.2016.02.019. 2016
4HCFC1, MMACHC, ZNF143
Inborn Error of Cobalamin Metabolism Associated with the Intracellular Accumulation of Transcobalamin-Bound Cobalamin and Mutations in ZNF143, Which Codes for a Transcriptional Activator.
Pupavac M, Watkins D, Petrella F, Fahiminiya S, Janer A, Cheung W, Gingras AC, Pastinen T, Muenzer J, Majewski J, Shoubridge EA, Rosenblatt DS.
Hum Mutat 37(9):976-82. doi: 10.1002/humu.23037. 2016
5HCFC1, THAP11, ZNF143
Genomic Determinants of THAP11/ZNF143/HCFC1 Complex Recruitment to Chromatin.
Vinckevicius A, Parker JB, Chakravarti D.
Mol Cell Biol 35(24):4135-46. doi: 10.1128/MCB.00477-15. 2015
6HCFC1, OGT
Distinct OGT-Binding Sites Promote HCF-1 Cleavage.
Bhuiyan T, Waridel P, Kapuria V, Zoete V, Herr W.
PLoS One 10(8):e0136636. doi: 10.1371/journal.pone.0136636. 2015
7HCFC1
HCFC1 loss-of-function mutations disrupt neuronal and neural progenitor cells of the developing brain.
Jolly LA, Nguyen LS, Domingo D, Sun Y, Barry S, Hancarova M, Plevova P, Vlckova M, Havlovicova M, Kalscheuer VM, Graziano C, Pippucci T, Bonora E, Sedlacek Z, Gecz J.
Hum Mol Genet 24(12):3335-47. doi: 10.1093/hmg/ddv083. 2015
8HCFC1, MMACHX
Multiple congenital anomalies in two boys with mutation in HCFC1 and cobalamin disorder.
Gérard M, Morin G, Bourillon A, Colson C, Mathieu S, Rabier D, Billette de Villemeur T, Ogier de Baulny H, Benoist JF.
Eur J Med Genet 58(3):148-53. doi: 10.1016/j.ejmg.2014.12.015. 2015
9HCFC1, THAP11, ZNF143
Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.
Parker JB, Yin H, Vinckevicius A, Chakravarti D.
Cell Rep 9(3):967-82. doi: 10.1016/j.celrep.2014.09.051. 2014
10HCFC1, MMACHC, MMACHX
An X-Linked Cobalamin Disorder Caused by Mutations in Transcriptional Coregulator HCFC1.
Yu HC, Sloan JL, Scharer G, Brebner A, Quintana AM, Achilly NP, Manoli I, Coughlin CR 2nd, Geiger EA, Schneck U, Watkins D, Suormala T, Van Hove JL, Fowler B, Baumgartner MR, Rosenblatt DS, Venditti CP, Shaikh TH.
Am J Hum Genet 93(3):506-14. doi: 10.1016/j.ajhg.2013.07.022. 2013
11HCFC1, KMT2E
Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1).
Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, Zhang F, Ding X, Wang C, Xiong S, Wang Z, Yuan J, Li Q, Zhang Y.
J Biol Chem 288(24):17532-43. doi: 10.1074/jbc.M112.439729. Epub 2013 Apr 29. 2013
12HCFC1
HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Lazarus MB, Jiang J, Kapuria V, Bhuiyan T, Janetzko J, Zandberg WF, Vocadlo DJ, Herr W, Walker S.
Science 342(6163):1235-9. doi: 10.1126/science.1243990. 2013
13HCFC1
The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion.
Iwata TN, Cowley TJ, Sloma M, Ji Y, Kim H, Qi L, Lee SS.
PLoS One 8(11):e78841. doi: 10.1371/journal.pone.0078841. 2013
14HCFC1, MRX3, YY1
A Noncoding, Regulatory Mutation Implicates HCFC1 in Nonsyndromic Intellectual Disability.
Huang L, Jolly LA, Willis-Owen S, Gardner A, Kumar R, Douglas E, Shoubridge C, Wieczorek D, Tzschach A, Cohen M, Hackett A, Field M, Froyen G, Hu H, Haas SA, Ropers HH, Kalscheuer VM, Corbett MA, Gecz J.
Am J Hum Genet 91(4):694-702. doi: 10.1016/j.ajhg.2012.08.011. Epub 2012 Sep 20. 2012
15BAP1, HCFC1
BAP1 loss defines a new class of renal cell carcinoma.
Peña-Llopis S, Vega-Rubín-de-Celis S, Liao A, Leng N, Pavía-Jiménez A, Wang S, Yamasaki T, Zhrebker L, Sivanand S, Spence P, Kinch L, Hambuch T, Jain S, Lotan Y, Margulis V, Sagalowsky AI, Summerour PB, Kabbani W, Wong SW, Grishin N, Laurent M, Xie XJ, Haudenschild CD, Ross MT, Bentley DR, Kapur P, Brugarolas J.
Nat Genet 44(7):751-9. doi: 10.1038/ng.2323. Erratum in: Nat Genet. 2012 Sep;44(9):1072. 2012
16BAP1, HCFC1, OGT
Loss of the tumor suppressor BAP1 causes myeloid transformation.
Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, LaFave LM, Abdel-Wahab O, Modrusan Z, Seshagiri S, Dong K, Lin Z, Balazs M, Suriben R, Newton K, Hymowitz S, Garcia-Manero G, Martin F, Levine RL, Dixit VM.
Science 337(6101):1541-6. 2012
17HCFC1
HCF-1 self-association via an interdigitated Fn3 structure facilitates transcriptional regulatory complex formation.
Park J, Lammers F, Herr W, Song JJ.
Proc Natl Acad Sci U S A 109(43):17430-5. doi: 10.1073/pnas.1208378109. Epub 2012 Oct 8. 2012
18ASXL1, BAP1, HCFC1
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, Olshen A, Rusch V, Ladanyi M.
Nat Genet 43(7):668-72. doi: 10.1038/ng.855. 2011
19HCFC1, OGT
Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.
Daou S, Mashtalir N, Hammond-Martel I, Pak H, Yu H, Sui G, Vogel JL, Kristie TM, Affar el B.
Proc Natl Acad Sci U S A 108(7):2747-52. Epub 2011 Feb 1. 2011
20HCFC1, OGT, THAP1, THAP3
The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias.
Mazars R, Gonzalez-de-Peredo A, Cayrol C, Lavigne AC, Vogel JL, Ortega N, Lacroix C, Gautier V, Huet G, Ray A, Monsarrat B, Kristie TM, Girard JP.
J Biol Chem 285(18):13364-71. Epub 2010 Mar 3. 2010
21BAP1, COX7C, HCFC1, YY1
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.
Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky E, Milot E, Shi Y, Affar el B.
Mol Cell Biol 30(21):5071-85. Epub 2010 Aug 30. 2010
22E2F1, HCFC1
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases.
Tyagi S, Herr W.
EMBO J 28(20):3185-95. Epub 2009 Sep 17.PMID: 19763085 2009
23BAP1, HCFC1
The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
Machida YJ, Machida Y, Vashisht AA, Wohlschlegel JA, Dutta A.
J Biol Chem 284(49):34179-88. Epub 2009 Oct 8.PMID: 19815555 2009
24BAP1, HCFC1
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.
Misaghi S, Ottosen S, Izrael-Tomasevic A, Arnott D, Lamkanfi M, Lee J, Liu J, O'Rourke K, Dixit VM, Wilson AC.
Mol Cell Biol 29(8):2181-92. Epub 2009 Feb 2.PMID: 19188440 2009
25HCFC1, THAP11
Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells.
Dejosez M, Krumenacker JS, Zitur LJ, Passeri M, Chu LF, Songyang Z, Thomson JA, Zwaka TP.
Cell 133(7):1162-74. Erratum in: Cell. 2008 Aug 22;134(4):692. PMID: 18585351 2008
26HCFC1
Association of the cellular coactivator HCF-1 with the Golgi apparatus in sensory neurons.
Kolb G, Kristie TM.
J Virol 82(19):9555-63. Epub 2008 Jul 30.PMID: 18667495 2008
27HCFC1
E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.
Tyagi S, Chabes AL, Wysocka J, Herr W.
Mol Cell 27(1):107-19.PMID: 17612494 2007
28HCFC1
A protein sequestering system reveals control of cellular programs by the transcriptional coactivator HCF-1.
Khurana B, Kristie TM.
J Biol Chem 279(32):33673-83. Epub 2004 Jun 8. 2004
29HCFC1
A switch in mitotic histone H4 lysine 20 methylation status is linked to M phase defects upon loss of HCF-1.
Julien E, Herr W.
Mol Cell 14(6):713-25.PMID: 15200950 2004
30HCFC1
HCF-1 functions as a coactivator for the zinc finger protein Krox20.
Luciano RL, Wilson AC.
J Biol Chem 278(51):51116-24. Epub 2003 Oct 6. 2003
31HCFC1
PDCD2 is a negative regulator of HCF-1 (C1).
Scarr RB, Sharp PA.
Oncogene 21(34):5245-54. 2002
32HCFC1, HCFC1R1
Interaction of HCF-1 with a cellular nuclear export factor.
Mahajan SS, Little MM, Vazquez R, Wilson AC.
J Biol Chem 277(46):44292-9. Epub 2002 Sep 15. 2002
33CREB3, HCFC1
Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP.
Freiman RN, Herr W.
Genes Dev 11(23):3122-7. 1997
34HCFC1
The chromosome localization and the HCF repeats of the human host cell factor gene (HCFC1) are conserved in the mouse homologue.
Frattini A, et al.
Genomics 32 : 277-280. 1996
35TMEM187, LAGE3, HCFC1
Characterization and fine localization of two new genes in Xq28 using the genomic sequence/EST database screening approach.
Faranda S, et al.
Genomics 34 : 323-327. 1996
36HCFC1
The complete sequence of the host cell factor 1 (HCFC1) gene and its promoter : a role for YY1 transcription factor in the regulation of its expression.
Zoppe M, et al.
Genomics 34 : 85-91. 1996
37HCFC1
The gene encoding the VP16-accessory protein HCF (HCFC1) resides in human Xq28 and is highly expressed in fetal tissues and the adult kidney.
Wilson AC, et al.
Genomics 25 : 462-468. 1995
38HCFC1, RENBP
The human genes encoding renin-binding protein and host cell factor are closely linked in Xq28 and transcribed in the same direction.
Faranda S, et al.
Gene 155 : 237-239. 1995
39ARHGAP4, HCFC1, NAA10, XESFBK
Isolation of new genes in distal Xq28 : transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of saccharomyces cerevisiae.
Tribioli C, et al.
Hum Mol Genet 3 : 1061-1067. 1994
40HCFC1
Genomic organization of the human VP16 accessory protein, a housekeeping gene (HCFC1) mapping to Xq28.
Frattini A, et al.
Genomics 23 : 30-35. 1994
41HCFC1
The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein.
Wilson AC, et al.
Cell 74 : 115-125. 1993