| 1 | HAS1, HAS2, HAS3
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| Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo- and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2 and HAS3.
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| Bart G, Vico NO, Hassinen A, Pujol FM, Deen AJ, Ruusala A, Tammi RH, Squire A, Heldin P, Kellokumpu S, Tammi MI.
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| J Biol Chem Biol Chem. 2015 Mar 20. pii: jbc.M115.640581. [Epub ahead of print]
2015
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| 2 | HAS1
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| Hyaluronan synthase 1: a mysterious enzyme with unexpected functions.
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| Siiskonen H, Oikari S, Pasonen-Seppänen S, Rilla K.
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| Front Immunol 6:43. doi: 10.3389/fimmu.2015.00043. eCollection 2015. Review.
2015
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| 3 | HAS1, HAS3, HBEGF
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| Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3.
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| Malaisse J, Bourguignon V, De Vuyst E, Lambert de Rouvroit C, Nikkels AF, Flamion B, Poumay Y.
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| J Invest Dermatol 134(8):2174-82. doi: 10.1038/jid.2014.147. Epub 2014 Mar 21.
2014
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| 4 | HAS1
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| Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat.
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| Siiskonen H, Kärnä R, Hyttinen JM, Tammi RH, Tammi MI, Rilla K.
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| Exp Cell Res 320(1):153-63. doi: 10.1016/j.yexcr.2013.09.021. Epub 2013 Oct 4.
2014
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| 5 | HAS1, HAS2, HAS3
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| Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.
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| Rilla K, Oikari S, Jokela TA, Hyttinen JM, Kärnä R, Tammi RH, Tammi MI.
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| J Biol Chem 288(8):5973-83. doi: 10.1074/jbc.M112.443879. Epub 2013 Jan 9.
2013
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| 6 | HAS1, HAS2, HAS3
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| Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.
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| Rilla K, Oikari S, Jokela TA, Hyttinen JM, Kärnä R, Tammi RH, Tammi MI.
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| J Biol Chem 288(8):5973-83. doi: 10.1074/jbc.M112.443879. Epub 2013 Jan 9.
2013
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| 7 | HAS1, HAS2
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| Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy.
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| Calve S, Isaac J, Gumucio JP, Mendias CL.
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| Am J Physiol Cell Physiol 303(5):C577-88. doi: 10.1152/ajpcell.00057.2012. Epub 2012 Jul 11. Erratum in: Am J Physiol Cell Physiol. 2012 Oct 15;303(8):C89 2012
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| 8 | HAS1
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| Identification and analysis of the human hyaluronan synthase 1 gene promoter reveals Smad3- and Sp3-mediated transcriptional induction.
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| Chen L, Neville RD, Michael DR, Martin J, Luo DD, Thomas DW, Phillips AO, Bowen T.
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| Matrix Biol 31(7-8):373-9. doi: 10.1016/j.matbio.2012.10.002. Epub 2012 Nov 1.
2012
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| 9 | HAS1, HAS2, HAS3
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| Perturbation of hyaluronan synthesis in the trabecular meshwork and the effects on outflow facility.
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| Keller KE, Sun YY, Yang YF, Bradley JM, Acott TS.
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| Invest Ophthalmol Vis Sci 53(8):4616-25. doi: 10.1167/iovs.12-9500.
2012
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| 10 | CD44, HAS1
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| Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction.
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| Meran S, Luo DD, Simpson R, Martin J, Wells A, Steadman R, Phillips AO.
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| J Biol Chem 286(20):17618-30. Epub 2011 Mar 25.
2011
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| 11 | HAS1
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| Estradiol inhibits hyaluronic acid synthase 1 expression in human vascular smooth muscle cells.
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| Freudenberger T, Röck K, Dai G, Dorn S, Mayer P, Heim HK, Fischer JW.
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| Basic Res Cardiol 106(6):1099-109. doi: 10.1007/s00395-011-0217-5. Epub 2011 Sep 8.
2011
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| 12 | HAS1, HAS2
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| Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity.
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| Dunn KM, Lee PK, Wilson CM, Iida J, Wasiluk KR, Hugger M, McCarthy JB.
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| Surgery 145(3):322-9.
2009
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| 13 | HAS1
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| Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancer.
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| Ghosh A, Kuppusamy H, Pilarski LM.
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| J Biol Chem 284(28):18840-50. Epub 2009 May 18.
2009
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| 14 | HAS1
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| Hyaluronic acid synthase-1 expression regulates bladder cancer growth, invasion, and angiogenesis through CD44.
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| Golshani R, Lopez L, Estrella V, Kramer M, Iida N, Lokeshwar VB.
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| Cancer Res 68(2):483-91. 2008
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| 15 | HAS1
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| Involvement of hyaluronan in regulation of fibroblast phenotype.
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| Meran S, Thomas D, Stephens P, Martin J, Bowen T, Phillips A, Steadman R.
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| J Biol Chem 282(35):25687-97. Epub 2007 Jul 3. 2007
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| 16 | HAS1
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| Role of hyaluronan and hyaluronan synthase in endometrial cancer.
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| Yabushita H, Kishida T, Fusano K, Kanyama K, Zhuo L, Itano N, Kimata K, Noguchi M.
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| Oncol Rep 13(6):1101-5. 2005
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| 17 | HAS1, HAS2
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| Mammalian hyaluronan synthases: investigation of functional relationships in vivo.
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| Spicer AP, Nguyen TK.
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| Biochem Soc Trans 27(2):109-15. Review. No abstract available. 1999
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| 18 | HAS1, HAS2, HAS3
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| Chromosomal localization of the human and mouse hyaluronan synthase genes.
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| Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA.
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| Genomics 41(3):493-7. 1997
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| 19 | HAS1
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| Molecular cloning of human hyaluronan synthase.
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| Itano N, et al.
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| Biochem Biophys Res Commun 222 : 816-820. 1996
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| 20 | HAS1
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| Functional cloning of the cDNA for a human hyaluronan synthase.
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| Shyjan AM, Heldin P, Butcher EC, Yoshino T, Briskin MJ.
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| J Biol Chem 271(38):23395-9. 1996
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