Citations for
1GUCA1A, GUCY2D
Neuronal Calcium Sensor GCAP1 Encoded by GUCA1A Exhibits Heterogeneous Functional Properties in Two Cases of Retinitis Pigmentosa.
Abbas S, Marino V, Weisschuh N, Kieninger S, Solaki M, Dell'Orco D, Koch KW.
ACS Chem Neurosci. May 20;11(10):1458-1470. doi: 10.1021/acschemneuro.0c00111. Epub 2020 Apr 29 2020
2CORD14, GUCA1A
Functional characterization of a novel GUCA1A missense mutation (D144G) in autosomal dominant cone dystrophy: A novel pathogenic GUCA1A variant in COD.
Tang S, Xia Y, Dai Y, Liu Y, Li J, Pan X, Chen P.
Mol Vis. Dec 31;25:921-xxx. eCollection 2019. 2019
3CORD14, GUCA1A
Clinical and genetic characteristics of 251 consecutive patients with macular and cone/cone-rod dystrophy.
Birtel J, Eisenberger T, Gliem M, Müller PL, Herrmann P, Betz C, Zahnleiter D, Neuhaus C, Lenzner S, Holz FG, Mangold E, Bolz HJ, Charbel Issa P.
Sci Rep. Mar 19;8(1):4824. doi: 10.1038/s41598-018-22096-0. 2018
4GUCA1A, GUCA1B
Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors.
Vinberg F, Peshenko IV, Chen J, Dizhoor AM, Kefalov VJ.
J Biol Chem. May 11;293(19):7457-7465. doi: 10.1074/jbc.RA117.001574. Epub 2018 Mar 16. 2018
5CORD14, GUCA1A
GUCA1A mutation causes maculopathy in a five-generation family with a wide spectrum of severity.
Chen X, Sheng X, Zhuang W, Sun X, Liu G, Shi X, Huang G, Mei Y, Li Y, Pan X, Liu Y, Li Z, Zhao Q, Yan B, Zhao C.
Genet Med. Aug;19(8):945-954. doi: 10.1038/gim.2016.217. Epub 2017 Jan 26. 2017
6GUCA1A
Allosteric communication pathways routed by Ca2+/Mg2+ exchange in GCAP1 selectively switch target regulation modes.
Marino V, Dell'Orco D.
Sci Rep. Oct 14;6:34277. doi: 10.1038/srep34277. 2016
7GUCA1A, GUCY2D
Dimerization Domain of Retinal Membrane Guanylyl Cyclase 1 (RetGC1) Is an Essential Part of Guanylyl Cyclase-activating Protein (GCAP) Binding Interface.
Peshenko IV, Olshevskaya EV, Dizhoor AM.
J Biol Chem. Aug 7;290(32):19584-96. doi: 10.1074/jbc.M115.661371. Epub 2015 Jun 22. 2015
8GUCA1A, GUCA1B
A novel Ca2+-feedback mechanism extends the operating range of mammalian rods to brighter light.
Vinberg F, Turunen TT, Heikkinen H, Pitkänen M, Koskelainen A.
J Gen Physiol. Oct;146(4):307-21. doi: 10.1085/jgp.201511412 2015
9GUCA1A, GUCA1B
Structural effects of Mg²⁺ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction.
Marino V, Sulmann S, Koch KW, Dell'Orco D.
Biochim Biophys Acta Sep;1853(9):2055-65. doi: 10.1016/j.bbamcr.2014.10.026. Epub 2014 Nov 4. 2015
10GUCA1A, GUCY2D
Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.
Makino CL, Wen XH, Olshevskaya EV, Peshenko IV, Savchenko AB, Dizhoor AM.
PLoS One. 7(10):e47637. doi: 10.1371/journal.pone.0047637. Epub 2012 Oct 17. 2012
11GUCA1A, GUCA1B
Differential Ca(2+) sensor guanylate cyclase activating protein modes of photoreceptor rod outer segment membrane guanylate cyclase signaling.
Duda T, Pertzev A, Sharma RK.
Biochemistry Jun 12;51(23):4650-7. doi: 10.1021/bi300572w. Epub 2012 Jun 1 2012
12GUCA1A, GUCA1B, GUCY2D, GUCY2F
Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors
Peshenko IV, Olshevskaya EV, Savchenko AB, Karan S, Palczewski K, Baehr W, Dizhoor AM
Biochemistry Jun 28;50(25):5590-600. doi: 10.1021/bi200491b. Epub 2011 Jun 6. 2011
13GUCA1A, GUCY2D, PDE2A
Ca(2+) sensor GCAP1: A constitutive element of the ONE-GC-modulated odorant signal transduction pathway.
Pertzev A, Duda T, Sharma RK.
Biochemistry 49(34):7303-13.PMID: 20684533 2010
14CORD14, GUCA1A
Mutations in the GUCA1A gene involved in hereditary cone dystrophies impair calcium-mediated regulation of guanylate cyclase.
Kitiratschky VB, Behnen P, Kellner U, Heckenlively JR, Zrenner E, Jägle H, Kohl S, Wissinger B, Koch KW.
Hum Mutat 30(8):E782-96. 2009
15GUCA1A
Binding of guanylyl cyclase activating protein 1 (GCAP1) to retinal guanylyl cyclase (RetGC1). The role of individual EF-hands.
Peshenko IV, Olshevskaya EV, Dizhoor AM.
J Biol Chem 283(31):21747-57. Epub 2008 Jun 9. 2008
16GUCA1A, GUCY2D
Binding of guanylyl cyclase activating protein 1 (GCAP1) to retinal guanylyl cyclase (RetGC1). The role of individual EF-hands.
Peshenko IV, Olshevskaya EV, Dizhoor AM.
J Biol Chem 283(31):21747-57. Epub 2008 Jun 9.PMID: 18541533 2008
17CORD14, GUCA1A
Mutation in the gene GUCA1A, encoding guanylate cyclase-activating protein 1, causes cone, cone-rod, and macular dystrophy.
Michaelides M, Wilkie SE, Jenkins S, Holder GE, Hunt DM, Moore AT, Webster AR.
Ophthalmology 112(8):1442-7. 2005
18CORD14, GUCA1A
A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD).
Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W.
Invest Ophthalmol Vis Sci 46(4):1124-32. 2005
19GUCA1A, GUCY2D
Guanylyl cyclase-activating proteins (GCAPs) are Ca2+/Mg2+ sensors: implications for photoreceptor guanylyl cyclase (RetGC) regulation in mammalian photoreceptors.
Peshenko IV, Dizhoor AM.
J Biol Chem 279(17):16903-6. Epub 2004 Mar 1. 2004
20CORD14, GUCA1A, GUCA1B
A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration.
Nishiguchi KM, Sokal I, Yang L, Roychowdhury N, Palczewski K, Berson EL, Dryja TP, Baehr W.
Invest Ophthalmol Vis Sci 45(11):3863-70. 2004
21GUCA1A
Analyses of the guanylate cyclase activating protein-1 gene promoter in the developing retina.
Coleman JE, Fuchs GE, Semple-Rowland SL.
Invest Ophthalmol Vis Sci 43(5):1335-43. 2002
22CORD14, GUCA1A
The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.
Newbold RJ, Deery EC, Walker CE, Wilkie SE, Srinivasan N, Hunt DM, Bhattacharya SS, Warren MJ.
Hum Mol Genet 10(1):47-54. 2001
23GUCA1A
Mapping sites in guanylyl cyclase activating protein-1 required for regulation of photoreceptor membrane guanylyl cyclases.
Krylov DM, et al.
J Biol Chem 274(16):10833-9. 1999
24CORD14, GUCA1A
A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1.
Payne AM, Downes SM, Bessant DA, Taylor R, Holder GE, Warren MJ, Bird AC, Bhattacharya SS.
Hum Mol Genet 7(2):273-7. 1998
25CORD14, GUCA1A
Constitutive activation of photoreceptor guanylate cyclase by Y99C mutant of GCAP-1. Possible role in causing human autosomal dominant cone degeneration.
Dizhoor AM, Boikov SG, Olshevskaya EV.
J Biol Chem 273 : 17311-17314. 1998
26GUCA1A, GUCA1B
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
Surguchov A, et al.
Genomics 39 : 312-322. 1997
27GUCA1A
Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein.
Palczewski K, et al.
Neuron 13 : 395-404. 1994
28GUCA1A
Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.
Subbaraya I, Ruiz CC, Helekar BS, Zhao X, Gorczyca WA, Pettenati MJ, Rao PN, Palczewski K, Baehr W.
J Biol Chem 269(49):31080-9. 1994