| 1 | GUCA1A, GUCY2D
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| Neuronal Calcium Sensor GCAP1 Encoded by GUCA1A Exhibits Heterogeneous Functional Properties in Two Cases of Retinitis Pigmentosa.
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| Abbas S, Marino V, Weisschuh N, Kieninger S, Solaki M, Dell'Orco D, Koch KW.
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| ACS Chem Neurosci. May 20;11(10):1458-1470. doi: 10.1021/acschemneuro.0c00111. Epub 2020 Apr 29 2020
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| 2 | CORD14, GUCA1A
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| Functional characterization of a novel GUCA1A missense mutation (D144G) in autosomal dominant cone dystrophy: A novel pathogenic GUCA1A variant in COD.
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| Tang S, Xia Y, Dai Y, Liu Y, Li J, Pan X, Chen P.
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| Mol Vis. Dec 31;25:921-xxx. eCollection 2019. 2019
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| 3 | CORD14, GUCA1A
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| Clinical and genetic characteristics of 251 consecutive patients with macular and cone/cone-rod dystrophy.
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| Birtel J, Eisenberger T, Gliem M, Müller PL, Herrmann P, Betz C, Zahnleiter D, Neuhaus C, Lenzner S, Holz FG, Mangold E, Bolz HJ, Charbel Issa P.
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| Sci Rep. Mar 19;8(1):4824. doi: 10.1038/s41598-018-22096-0. 2018
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| 4 | GUCA1A, GUCA1B
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| Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors.
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| Vinberg F, Peshenko IV, Chen J, Dizhoor AM, Kefalov VJ.
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| J Biol Chem. May 11;293(19):7457-7465. doi: 10.1074/jbc.RA117.001574. Epub 2018 Mar 16. 2018
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| 5 | CORD14, GUCA1A
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| GUCA1A mutation causes maculopathy in a five-generation family with a wide spectrum of severity.
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| Chen X, Sheng X, Zhuang W, Sun X, Liu G, Shi X, Huang G, Mei Y, Li Y, Pan X, Liu Y, Li Z, Zhao Q, Yan B, Zhao C.
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| Genet Med. Aug;19(8):945-954. doi: 10.1038/gim.2016.217. Epub 2017 Jan 26. 2017
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| 6 | GUCA1A
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| Allosteric communication pathways routed by Ca2+/Mg2+ exchange in GCAP1 selectively switch target regulation modes.
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| Marino V, Dell'Orco D.
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| Sci Rep. Oct 14;6:34277. doi: 10.1038/srep34277. 2016
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| 7 | GUCA1A, GUCY2D
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| Dimerization Domain of Retinal Membrane Guanylyl Cyclase 1 (RetGC1) Is an Essential Part of Guanylyl Cyclase-activating Protein (GCAP) Binding Interface.
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| Peshenko IV, Olshevskaya EV, Dizhoor AM.
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| J Biol Chem. Aug 7;290(32):19584-96. doi: 10.1074/jbc.M115.661371. Epub 2015 Jun 22. 2015
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| 8 | GUCA1A, GUCA1B
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| A novel Ca2+-feedback mechanism extends the operating range of mammalian rods to brighter light.
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| Vinberg F, Turunen TT, Heikkinen H, Pitkänen M, Koskelainen A.
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| J Gen Physiol. Oct;146(4):307-21. doi: 10.1085/jgp.201511412 2015
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| 9 | GUCA1A, GUCA1B
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| Structural effects of Mg²⁺ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction.
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| Marino V, Sulmann S, Koch KW, Dell'Orco D.
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| Biochim Biophys Acta Sep;1853(9):2055-65. doi: 10.1016/j.bbamcr.2014.10.026. Epub 2014 Nov 4. 2015
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| 10 | GUCA1A, GUCY2D
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| Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.
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| Makino CL, Wen XH, Olshevskaya EV, Peshenko IV, Savchenko AB, Dizhoor AM.
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| PLoS One. 7(10):e47637. doi: 10.1371/journal.pone.0047637. Epub 2012 Oct 17. 2012
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| 11 | GUCA1A, GUCA1B
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| Differential Ca(2+) sensor guanylate cyclase activating protein modes of photoreceptor rod outer segment membrane guanylate cyclase signaling.
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| Duda T, Pertzev A, Sharma RK.
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| Biochemistry Jun 12;51(23):4650-7. doi: 10.1021/bi300572w. Epub 2012 Jun 1 2012
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| 12 | GUCA1A, GUCA1B, GUCY2D, GUCY2F
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| Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors
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| Peshenko IV, Olshevskaya EV, Savchenko AB, Karan S, Palczewski K, Baehr W, Dizhoor AM
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| Biochemistry Jun 28;50(25):5590-600. doi: 10.1021/bi200491b. Epub 2011 Jun 6. 2011
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| 13 | GUCA1A, GUCY2D, PDE2A
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| Ca(2+) sensor GCAP1: A constitutive element of the ONE-GC-modulated odorant signal transduction pathway.
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| Pertzev A, Duda T, Sharma RK.
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| Biochemistry 49(34):7303-13.PMID: 20684533 2010
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| 14 | CORD14, GUCA1A
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| Mutations in the GUCA1A gene involved in hereditary cone dystrophies impair calcium-mediated regulation of guanylate cyclase.
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| Kitiratschky VB, Behnen P, Kellner U, Heckenlively JR, Zrenner E, Jägle H, Kohl S, Wissinger B, Koch KW.
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| Hum Mutat 30(8):E782-96. 2009
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| 15 | GUCA1A
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| Binding of guanylyl cyclase activating protein 1 (GCAP1) to retinal guanylyl cyclase (RetGC1). The role of individual EF-hands.
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| Peshenko IV, Olshevskaya EV, Dizhoor AM.
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| J Biol Chem 283(31):21747-57. Epub 2008 Jun 9. 2008
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| 16 | GUCA1A, GUCY2D
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| Binding of guanylyl cyclase activating protein 1 (GCAP1) to retinal guanylyl cyclase (RetGC1). The role of individual EF-hands.
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| Peshenko IV, Olshevskaya EV, Dizhoor AM.
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| J Biol Chem 283(31):21747-57. Epub 2008 Jun 9.PMID: 18541533 2008
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| 17 | CORD14, GUCA1A
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| Mutation in the gene GUCA1A, encoding guanylate cyclase-activating protein 1, causes cone, cone-rod, and macular dystrophy.
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| Michaelides M, Wilkie SE, Jenkins S, Holder GE, Hunt DM, Moore AT, Webster AR.
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| Ophthalmology 112(8):1442-7. 2005
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| 18 | CORD14, GUCA1A
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| A novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD).
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| Sokal I, Dupps WJ, Grassi MA, Brown J Jr, Affatigato LM, Roychowdhury N, Yang L, Filipek S, Palczewski K, Stone EM, Baehr W.
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| Invest Ophthalmol Vis Sci 46(4):1124-32. 2005
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| 19 | GUCA1A, GUCY2D
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| Guanylyl cyclase-activating proteins (GCAPs) are Ca2+/Mg2+ sensors: implications for photoreceptor guanylyl cyclase (RetGC) regulation in mammalian photoreceptors.
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| Peshenko IV, Dizhoor AM.
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| J Biol Chem 279(17):16903-6. Epub 2004 Mar 1. 2004
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| 20 | CORD14, GUCA1A, GUCA1B
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| A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration.
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| Nishiguchi KM, Sokal I, Yang L, Roychowdhury N, Palczewski K, Berson EL, Dryja TP, Baehr W.
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| Invest Ophthalmol Vis Sci 45(11):3863-70. 2004
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| 21 | GUCA1A
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| Analyses of the guanylate cyclase activating protein-1 gene promoter in the developing retina.
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| Coleman JE, Fuchs GE, Semple-Rowland SL.
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| Invest Ophthalmol Vis Sci 43(5):1335-43. 2002
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| 22 | CORD14, GUCA1A
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| The destabilization of human GCAP1 by a proline to leucine mutation might cause cone-rod dystrophy.
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| Newbold RJ, Deery EC, Walker CE, Wilkie SE, Srinivasan N, Hunt DM, Bhattacharya SS, Warren MJ.
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| Hum Mol Genet 10(1):47-54. 2001
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| 23 | GUCA1A
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| Mapping sites in guanylyl cyclase activating protein-1 required for regulation of photoreceptor membrane guanylyl cyclases.
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| Krylov DM, et al.
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| J Biol Chem 274(16):10833-9. 1999
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| 24 | CORD14, GUCA1A
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| A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1.
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| Payne AM, Downes SM, Bessant DA, Taylor R, Holder GE, Warren MJ, Bird AC, Bhattacharya SS.
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| Hum Mol Genet 7(2):273-7. 1998
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| 25 | CORD14, GUCA1A
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| Constitutive activation of photoreceptor guanylate cyclase by Y99C mutant of GCAP-1. Possible role in causing human autosomal dominant cone degeneration.
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| Dizhoor AM, Boikov SG, Olshevskaya EV.
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| J Biol Chem 273 : 17311-17314. 1998
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| 26 | GUCA1A, GUCA1B
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| The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1).
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| Surguchov A, et al.
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| Genomics 39 : 312-322. 1997
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| 27 | GUCA1A
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| Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein.
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| Palczewski K, et al.
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| Neuron 13 : 395-404. 1994
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| 28 | GUCA1A
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| Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.
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| Subbaraya I, Ruiz CC, Helekar BS, Zhao X, Gorczyca WA, Pettenati MJ, Rao PN, Palczewski K, Baehr W.
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| J Biol Chem 269(49):31080-9. 1994
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