| 1 | GATA4, GSN, MAPK14, NPPB
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| Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation.
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| Hu WS, Ho TJ, Pai P, Chung LC, Kuo CH, Chang SH, Tsai FJ, Tsai CH, Jie YC, Liou YM, Huang CY.
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| Mol Cell Biochem 390(1-2):263-70. doi: 10.1007/s11010-014-1977-7. Epub 2014 Feb 7.
2014
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| 2 | GSN
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| Mutational spectrum of Gelsolin and its down regulation is associated with breast cancer.
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| Baig RM, Mahjabeen I, Sabir M, Masood N, Ali K, Malik FA, Kayani MA.
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| Dis Markers 34(2):71-80. doi: 10.3233/DMA-120952.
2013
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| 3 | ACSL1, GSN
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| Long chain acyl CoA synthetase 1 and gelsolin are oppositely regulated in adipogenesis and lipogenesis.
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| Mukherjee R, Yun JW.
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| Biochem Biophys Res Commun 420(3):588-93. Epub 2012 Mar 16.
2012
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| 4 | GSN, STX4
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| Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis.
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| Kalwat MA, Wiseman DA, Luo W, Wang Z, Thurmond DC.
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| Mol Endocrinol 26(1):128-41. doi: 10.1210/me.2011-1112. Epub 2011 Nov 22. 2012
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| 5 | CAAG, GSN
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| Clinical features and haplotype analysis of newly identified Japanese patients with gelsolin-related familial amyloidosis of Finnish type.
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| Taira M, Ishiura H, Mitsui J, Takahashi Y, Hayashi T, Shimizu J, Matsukawa T, Saito N, Okada K, Tsuji S, Sawamura H, Amano S, Goto J, Tsuji S.
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| Neurogenetics 13(3):237-43. doi: 10.1007/s10048-012-0330-0. Epub 2012 May 24. 2012
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| 6 | GSN
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| Gelsolin in cerebrospinal fluid as a potential biomarker of epilepsy.
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| Peng X, Zhang X, Wang L, Zhu Q, Luo J, Wang W, Wang X.
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| Neurochem Res 36(12):2250-8. doi: 10.1007/s11064-011-0549-4. Epub 2011 Jul 24.
2011
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| 7 | GSN
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| Gelsolin negatively regulates the activity of tumor suppressor p53 through their physical interaction in hepatocarcinoma HepG2 cells.
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| An JH, Kim JW, Jang SM, Kim CH, Kang EJ, Choi KH.
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| Biochem Biophys Res Commun 412(1):44-9. doi: 10.1016/j.bbrc.2011.07.034. Epub 2011 Jul 23.
2011
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| 8 | GSN
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| Role and regulation of sperm gelsolin prior to fertilization.
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| Finkelstein M, Etkovitz N, Breitbart H.
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| J Biol Chem 285(51):39702-9. doi: 10.1074/jbc.M110.170951. Epub 2010 Oct 11.
2010
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| 9 | GSN
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| Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia.
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| Mburu P, Romero MR, Hilton H, Parker A, Townsend S, Kikkawa Y, Brown SD.
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| PLoS One 5(7):e11627. doi: 10.1371/journal.pone.0011627.
2010
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| 10 | GSN
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| Impact of actin filament stabilization on adult hippocampal and olfactory bulb neurogenesis.
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| Kronenberg G, Gertz K, Baldinger T, Kirste I, Eckart S, Yildirim F, Ji S, Heuser I, Schröck H, Hörtnagl H, Sohr R, Djoufack PC, Jüttner R, Glass R, Przesdzing I, Kumar J, Freyer D, Hellweg R, Kettenmann H, Fink KB, Endres M.
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| J Neurosci 30(9):3419-31. doi: 10.1523/JNEUROSCI.4231-09.2010.
2010
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| 11 | GSN
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| Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system.
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| Gonçalves AF, Dias NG, Moransard M, Correia R, Pereira JA, Witke W, Suter U, Relvas JB.
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| Glia 58(6):706-15. doi: 10.1002/glia.20956.
2010
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| 12 | GSN
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| Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin.
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| Nag S, Ma Q, Wang H, Chumnarnsilpa S, Lee WL, Larsson M, Kannan B, Hernandez-Valladares M, Burtnick LD, Robinson RC.
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| Proc Natl Acad Sci U S A 106(33):13713-8. Epub 2009 Aug 4.
2009
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| 13 | GSN
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| Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.
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| Li GH, Shi Y, Chen Y, Sun M, Sader S, Maekawa Y, Arab S, Dawood F, Chen M, De Couto G, Liu Y, Fukuoka M, Yang S, Da Shi M, Kirshenbaum LA, McCulloch CA, Liu P.
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| Circ Res 104(7):896-904. Epub 2009 Feb 26.
2009
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| 14 | CAPG, GSN
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| Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
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| Zhang R, Zhou L, Li Q, Liu J, Yao W, Wan H.
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| Am J Respir Cell Mol Biol 41(4):467-75. Epub 2009 Feb 2.
2009
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| 15 | GSN
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| The ubiquitin-proteasome pathway mediates gelsolin protein downregulation in pancreatic cancer.
|
| Ni XG, Zhou L, Wang GQ, Liu SM, Bai XF, Liu F, Peppelenbosch MP, Zhao P.
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| Mol Med 14(9-10):582-9.
2008
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| 16 | CNN1, GSN
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| Two distinct sites of interaction form the calponin: gelsolin complex and two calcium switches control its activity.
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| Ferjani I, Fattoum A, Maciver SK, Manai M, Benyamin Y, Roustan C.
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| Biochim Biophys Acta 1774(7):952-8. Epub 2007 May 6.
2007
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| 17 | GSN
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| Posttranslational N-myristoylation is required for the anti-apoptotic activity of human tGelsolin, the C-terminal caspase cleavage product of human gelsolin.
|
| Sakurai N, Utsumi T.
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| J Biol Chem 281(20):14288-95. Epub 2006 Mar 23. 2006
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| 18 | NME2, PDGFC, EID1, GSN
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| Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling.
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| Gordon GJ, Rockwell GN, Jensen RV, Rheinwald JG, Glickman JN, Aronson JP, Pottorf BJ, Nitz MD, Richards WG, Sugarbaker DJ, Bueno R.
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| Am J Pathol 166(6):1827-40. 2005
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| 19 | CHST6, COL8A2, GLA, GSN, KRT12, KRT3, M1S1, STS, TGFBI
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| The molecular genetics of the corneal dystrophies--current status.
|
| Klintworth GK.
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| Front Biosci 8:d687-713. Review.
2003
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| 20 | CAAG, GSN
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| The disintegration of a molecule: the role of gelsolin in FAF, familial amyloidosis (Finnish type).
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| Robinson RC, Choe S, Burtnick LD.
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| Proc Natl Acad Sci U S A 98(5):2117-8. 2001
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| 21 | CFL1, GSN
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| Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells.
|
| Southwick FS.
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| Proc Natl Acad Sci U S A 97(13):6936-8. No abstract available. 2000
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| 22 | CAAG, GSN
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| Elucidating the mechanism of familial amyloidosis- finnish type: NMR studies of human gelsolin domain 2.
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| Kazmirski SL, Howard MJ, Isaacson RL, Fersht AR.
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| Proc Natl Acad Sci U S A 97(20):10706-11. 2000
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| 23 | GSN
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| Gelsolin, a multifunctional actin regulatory protein.
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| Sun HQ, Yamamoto M, Mejillano M, Yin HL.
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| J Biol Chem 274(47):33179-82. Review. No abstract available 1999
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| 24 | CASP3, GSN
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| Caspase-3-generated fragment of gelsolin : effector of morphological change in apoptosis.
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| Kothakota S, Azuma T, Reinhard C, Klippel A, Tang J, Chu K, McGarry TJ, Kirschner MW, Koths K, Kwiatkowski DJ, Williams LT.
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| Science 278(5336):294-8. 1997
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| 25 | CAAG, GSN
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| In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis.
|
| Kangas H, et al.
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| Hum Mol Genet 5 : 1237-1243. 1996
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| 26 | CAAG, GSN
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| Asp187Asn mutation of gelsolin in an American kindred with familial amyloidosis, Finnish type (FAP IV).
|
| Steiner RD, et al.
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| Hum Genet 95 : 327-330. 1995
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| 27 | BRINP1, GSN
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| Gelsolin : A candidate for suppressor of human bladder cancer.
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| Tanaka M, et al.
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| Cancer Res 55 : 3228-3232. 1995
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| 28 | CYP11B@, GSN
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| Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree.
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| Pascoe L, et al.
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| J Clin Invest 96 : 2236-2246. 1995
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| 29 | CAAG, GSN
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| Haplotype analysis in gelsolin-related amyloidosis reveals independent origin of identical mutation (G654A) of gelsolin in Finland and Japan.
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| Paunio T, et al.
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| Hum Mutat 6 : 60-65. 1995
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| 30 | GSN
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| Solid-phase minisequencing test reveals Asp187-Asn(G654-A) mutation of gelsolin in all affected individuals wirh Finnish type of familial amyloidosis.
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| Paunio T, et al.
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| Genomics 13 : 237-239. 1992
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| 31 | GSN
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| Homozygosity for the Asn187 gelsolin mutation in Finnish-type familial amyloidosis is associated with severe renal disease.
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| Maury CPJ, et al.
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| Genomics 13 : 902-903. 1992
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| 32 | GSN
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| Familial amyloidosis, Finnish type : G654-a mutation of the gelsolin gene in Finnish families and an unrelated American family.
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| de la Chapelle A, et al.
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| Genomics 13 : 898-901. 1992
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| 33 | GSN
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| Exclusion of the gelsolin gene on 9q32-34 as the cause of familial lattice corneal dystrophy type 1.
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| Wiens A, et al.
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| Am J Hum Genet 51 : 156-160. 1992
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| 34 | GSN
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| Gelsolin-derived familial amyloidosis caused by asparagine or tyrosine substitution for aspartic acid at residue 187.
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| de La Chapelle A, et al.
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| Nat Genet 2 : 157-160. 1992
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| 35 | GSN
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| Finnish type of familial amyloidosis : cosegregation of Asp187-Asn mutation of gelsolin with the disease in three large families.
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| Hiltunen T, et al.
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| Am J Hum Genet 49 : 522-528. 1991
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| 36 | GSN
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| Amyloidosis due to a mutation of gelsolin gene in an American family with lattice corneal dystrophy type II.
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| Gorevic PD, et al.
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| N Engl J Med 325 : 1780-1785. 1991
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| 37 | GSN
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| Dinucleotide repeat polymorphism at the GSN locus (9q32-34).
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| Kwiatkowski DJ, et al.
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| Nucleic Acids Res 19 : 967. 1991
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| 38 | GSN
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| Gelsolin-related amyloidosis. Identification of the amyloid protein in Finnish hereditary amyloidosis as a fragment of variant gelsolin.
|
| Maury CPJ.
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| J Clin Invest 87 : 1195-1199. 1991
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| 39 | GSN
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| Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein.
|
| Haltia M, et al.
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| Biochem Biophys Res Commun 167 : 927-932. 1990
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| 40 | CTLN1, DYT1, GSN, TOR1A
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| Highly informative (GT)n polymorphisms from 9q32-34 permit creation of a high resolution map and delineation of a region likely to contain genes for torsion dystonia (DYT1), tuberous sclerosis (TSC1), and nail-patella syndrome (NPS1).
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| Kwiatkowski DJ, et al.
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| Am J Hum Genet 47 : A187. 1990
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| 41 | GSN
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| Finnish hereditary amyloidosis. Amino acid sequence homology between the amyloid fibril protein and human plasma gelsoline.
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| Maury CPJ, et al.
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| FEBS Lett 260 : 85-87. 1990
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| 42 | GSN
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| Finnish hereditary amyloidosis is caused by a single nucleotide substitution in the gelsolin gene.
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| Maury CPJ, et al.
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| FEBS Lett 276 : 75-77. 1990
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| 43 | GSN
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| Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type.
|
| Ghiso J, et al.
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| Biochem J 272 : 827-830. 1990
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| 44 | GSN
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| The gelsolin (GSN) cDNA clone, from 9q32-34, identifies BcII and StuI RFLPs.
|
| Kwiatkowski DJ, et al.
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| Nucleic Acids Res 17 : 4425. 1989
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| 45 | GSN
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| Pieces in the actin-severing protein puzzle.
|
| Matsudaira P, et al.
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| Cell 54 : 139-140. 1988
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| 46 | GSN
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| Localization of gelsolin proximal to ABL on chromosome 9.
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| Kwiatkowski DJ, et al.
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| Am J Hum Genet 42 : 565-572. 1988
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| 47 | GSN
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| Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.
|
| Kwiatkowski DJ, et al.
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| Nature 323 : 455-458. 1986
|