Citations for
1GRM1, GRM5
mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus.
Sun YG, Rupprecht V, Zhou L, Dasgupta R, Seibt F, Beierlein M.
J Neurosci 36(30):7886-96. doi: 10.1523/JNEUROSCI.0409-16.2016. 2016
2FMR1, GABRB3, GRM5
Hippocampal dysregulation of FMRP/mGluR5 signaling in engrailed-2 knockout mice: a model of autism spectrum disorders.
Provenzano G, Sgadò P, Genovesi S, Zunino G, Casarosa S, Bozzi Y.
Neuroreport 26(18):1101-5. doi: 10.1097/WNR.0000000000000477. 2015
3GRM1, GRM5
Cooperative signaling between homodimers of metabotropic glutamate receptors 1 and 5.
Sevastyanova TN, Kammermeier PJ.
Mol Pharmacol 86(5):492-504. doi: 10.1124/mol.114.093468. Epub 2014 Aug 11. 2014
4GRM5, HOMER1
Homer1 mediates acute stress-induced cognitive deficits in the dorsal hippocampus.
Wagner KV, Hartmann J, Mangold K, Wang XD, Labermaier C, Liebl C, Wolf M, Gassen NC, Holsboer F, Rein T, Müller MB, Schmidt MV.
J Neurosci 33(9):3857-64. doi: 10.1523/JNEUROSCI.4333-12.2013. 2013
5GRM1, GRM5
Agonist-dependent signaling by group I metabotropic glutamate receptors is regulated by association with lipid domains.
Kumari R, Castillo C, Francesconi A.
J Biol Chem 288(44):32004-19. doi: 10.1074/jbc.M113.475863. Epub 2013 Sep 17. 2013
6ARC, GRM5
Activation of intracellular metabotropic glutamate receptor 5 in striatal neurons leads to up-regulation of genes associated with sustained synaptic transmission including Arc/Arg3.1 protein.
Kumar V, Fahey PG, Jong YJ, Ramanan N, O'Malley KL.
J Biol Chem 287(8):5412-25. doi: 10.1074/jbc.M111.301366. Epub 2011 Dec 16. 2012
7GRM5
Constitutive internalization and recycling of metabotropic glutamate receptor 5 (mGluR5).
Trivedi RR, Bhattacharyya S.
Biochem Biophys Res Commun 427(1):185-90. doi: 10.1016/j.bbrc.2012.09.040. Epub 2012 Sep 17. 2012
8GRM5, SHANK3
Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Böckers TM, Dityatev A, Sala C.
J Biol Chem 286(40):34839-50. doi: 10.1074/jbc.M111.258384. Epub 2011 Jul 27. 2011
9GRM5, SLC9A3R2
The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons.
Filippov AK, Simon J, Barnard EA, Brown DA.
J Neurosci 30(33):11068-72.PMID: 20720114 2010
10GRM5
The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice.
Chen HH, Stoker A, Markou A.
Psychopharmacology (Berl) 209(4):343-50. Epub 2010 Mar 10.PMID: 20217053 2010
11GRM1, GRM5
Differential distribution of group I metabotropic glutamate receptors in developing human cortex.
Boer K, Encha-Razavi F, Sinico M, Aronica E.
Brain Res 1324:24-33. Epub 2010 Feb 10.PMID: 20149785 2010
12GOPC, GRM5
The PDZ domain protein CAL interacts with mGluR5a and modulates receptor expression.
Cheng S, Zhang J, Zhu P, Ma Y, Xiong Y, Sun L, Xu J, Zhang H, He J.
J Neurochem 112(3):588-98. Epub 2009 Oct 26. 2010
13GRM5, NECAB2
The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function.
Canela L, Fernández-Dueñas V, Albergaria C, Watanabe M, Lluís C, Mallol J, Canela EI, Franco R, Luján R, Ciruela F.
J Neurochem 111(2):555-67. Epub 2009 Aug 18.PMID: 19694902 2009
14GRM5, NCDN
Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling.
Wang H, Westin L, Nong Y, Birnbaum S, Bendor J, Brismar H, Nestler E, Aperia A, Flajolet M, Greengard P.
Science 326(5959):1554-7.PMID: 20007903 2009
15GRM5
Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts.
Jong YJ, Kumar V, O'Malley KL.
J Biol Chem 284(51):35827-38. Epub .PMID: 19840937 2009
16ADRBK1, GRM5
Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons.
Ribeiro FM, Ferreira LT, Paquet M, Cregan T, Ding Q, Gros R, Ferguson SS.
J Biol Chem 284(35):23444-53. Epub 2009 Jun 29.PMID: 19564331 2009
17GRM5
Roles of mGluR5 in synaptic function and plasticity of the mouse thalamocortical pathway.
She WC, Quairiaux C, Albright MJ, Wang YC, Sanchez DE, Chang PS, Welker E, Lu HC.
Eur J Neurosci 29(7):1379-96. Epub 2009 Mar 23.PMID: 19519626 2009
18GRM5
mGluR5 has a critical role in inhibitory learning.
Xu J, Zhu Y, Contractor A, Heinemann SF.
J Neurosci 29(12):3676-84.PMID: 19321764 2009
19CALM1, GRM5
Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.
Lee JH, Lee J, Choi KY, Hepp R, Lee JY, Lim MK, Chatani-Hinze M, Roche PA, Kim DG, Ahn YS, Kim CH, Roche KW.
Proc Natl Acad Sci U S A 105(34):12575-80. Epub 2008 Aug 20. 2008
20GRM5
mGluR5 regulates glutamate-dependent development of the mouse somatosensory cortex.
Wijetunge LS, Till SM, Gillingwater TH, Ingham CA, Kind PC.
J Neurosci 28(49):13028-37.PMID: 19052194 2008
21GRM1, GRM5
Endogenous homer proteins regulate metabotropic glutamate receptor signaling in neurons.
Kammermeier PJ.
J Neurosci 28(34):8560-7.PMID: 18716215 2008
22FRAXA, GRM5, FMR1
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.
Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST.
Proc Natl Acad Sci U S A 104(39):15537-42. Epub 2007 Sep 19. 2007
23GRM5, SLC9A3R2
The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity.
Paquet M, Asay MJ, Fam SR, Inuzuka H, Castleberry AM, Oller H, Smith Y, Yun CC, Traynelis SF, Hall RA.
J Biol Chem 281(40):29949-61. Epub 2006 Aug 4. 2006
24GRM5
Differential expression of mGluR5 in human lumbosacral motoneurons.
Anneser JM, Ince PG, Shaw PJ, Borasio GD.
Neuroreport 15(2):271-3. 2004
25GRM5
Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.
Malherbe P, Kew JN, Richards JG, Knoflach F, Kratzeisen C, Zenner MT, Faull RL, Kemp JA, Mutel V.
Brain Res Mol Brain Res 109(1-2):168-78. 2002
26GRM5
Characterization of mGluR5R, a novel, metabotropic glutamate receptor 5-related gene.
Bates B, Xie Y, Taylor N, Johnson J, Wu L, Kwak S, Blatcher M, Gulukota K, Paulsen JE.
Brain Res Mol Brain Res 109(1-2):18-33. 2002
27GRM1, GRM5, HOMER1, HOMER2, HOMER3
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors.
Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF.
Neuron 21(4):717-26 1998
28GRM1, GRM5, HOMER1, HOMER2, HOMER3
Homer: a protein that selectively binds metabotropic glutamate receptors.
Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF.
Nature 386(6622):284-8 1997
29GRM5
Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5.
Daggett LP, Sacaan AI, Akong M, Rao SP, Hess SD, Liaw C, Urrutia A, Jachec C, Ellis SB, Dreessen J, et al.
Neuropharmacology 34(8):871-86 1995
30GRM5
Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.
Minakami R, et al.
Biochem Biophys Res Commun 199(3):1136-43 1994