Citations for
1GRM1, SCA44
Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.
Watson LM, Bamber E, Schnekenberg RP, Williams J, Bettencourt C, Lickiss J, Jayawant S, Fawcett K, Clokie S, Wallis Y, Clouston P, Sims D, Houlden H, Becker EBE, Németh AH.
Am J Hum Genet 101(3):451-458. doi: 10.1016/j.ajhg.2017.08.005. 2017
2GRM1, SCA44
Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.
Watson LM, Bamber E, Schnekenberg RP, Williams J, Bettencourt C, Jayawant S, Lickiss J, Fawcett K, Clokie S, Wallis Y, Clouston P, Sims D, Houlden H, Becker EBE, Németh AH.
Am J Hum Genet 101(4):638. doi: 10.1016/j.ajhg.2017.09.006. No abstract available. 2017
3GRM1
A Critical Role for Ubiquitination in the Endocytosis of Glutamate Receptors.
Gulia R, Sharma R, Bhattacharyya S.
J Biol Chem 292(4):1426-1437. doi: 10.1074/jbc.M116.752105. Epub 2016 Dec 23. 2017
4GRM1, SCA44
Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.
Watson LM, Bamber E, Schnekenberg RP, Williams J, Bettencourt C, Lickiss J, Jayawant S, Fawcett K, Clokie S, Wallis Y, Clouston P, Sims D, Houlden H, Becker EBE, Németh AH.
Am J Hum Genet 101(5):866. doi: 10.1016/j.ajhg.2017.10.008. No abstract available. 2017
5GRM1, GRM5
mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus.
Sun YG, Rupprecht V, Zhou L, Dasgupta R, Seibt F, Beierlein M.
J Neurosci 36(30):7886-96. doi: 10.1523/JNEUROSCI.0409-16.2016. 2016
6GRM1, TRMU
The Role of a Novel TRMT1 Gene Mutation and Rare GRM1 Gene Defect in Intellectual Disability in Two Azeri Families.
Davarniya B, Hu H, Kahrizi K, Musante L, Fattahi Z, Hosseini M, Maqsoud F, Farajollahi R, Wienker TF, Ropers HH, Najmabadi H.
PLoS One 10(8):e0129631. doi: 10.1371/journal.pone.0129631. eCollection 2015. 2015
7GRM1, NRG1
Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons.
Ledonne A, Nobili A, Latagliata EC, Cavallucci V, Guatteo E, Puglisi-Allegra S, D'Amelio M, Mercuri NB.
Mol Psychiatry 20(8):959-73. doi: 10.1038/mp.2014.109. Epub 2014 Sep 30. 2015
8GRM1
Metabotropic glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in mGluR1a/b dimers in vivo.
Techlovská Š, Chambers JN, Dvořáková M, Petralia RS, Wang YX, Hájková A, Nová A, Franková D, Prezeau L, Blahos J.
Neuropharmacology 86:329-336. doi: 10.1016/j.neuropharm.2014.08.011. Epub 2014 Aug 23. 2014
9GRM1, GRM5
Cooperative signaling between homodimers of metabotropic glutamate receptors 1 and 5.
Sevastyanova TN, Kammermeier PJ.
Mol Pharmacol 86(5):492-504. doi: 10.1124/mol.114.093468. Epub 2014 Aug 11. 2014
10GRM1, STIM1
STIM1 controls neuronal Ca˛⁺ signaling, mGluR1-dependent synaptic transmission, and cerebellar motor behavior.
Hartmann J, Karl RM, Alexander RP, Adelsberger H, Brill MS, Rühlmann C, Ansel A, Sakimura K, Baba Y, Kurosaki T, Misgeld T, Konnerth A.
Neuron 82(3):635-44. doi: 10.1016/j.neuron.2014.03.027. 2014
11GRM1
GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.
Nord KH, Lilljebjörn H, Vezzi F, Nilsson J, Magnusson L, Tayebwa J, de Jong D, Bovée JV, Hogendoorn PC, Szuhai K.
Nat Genet 46(5):474-7. doi: 10.1038/ng.2927. Epub 2014 Mar 23. 2014
12GRM1
The synaptic targeting of mGluR1 by its carboxyl-terminal domain is crucial for cerebellar function.
Ohtani Y, Miyata M, Hashimoto K, Tabata T, Kishimoto Y, Fukaya M, Kase D, Kassai H, Nakao K, Hirata T, Watanabe M, Kano M, Aiba A.
J Neurosci 34(7):2702-12. doi: 10.1523/JNEUROSCI.3542-13.2014. 2014
13GRM1, GRM5
Agonist-dependent signaling by group I metabotropic glutamate receptors is regulated by association with lipid domains.
Kumari R, Castillo C, Francesconi A.
J Biol Chem 288(44):32004-19. doi: 10.1074/jbc.M113.475863. Epub 2013 Sep 17. 2013
14GRM1
Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor.
DiRaddo JO, Pshenichkin S, Gelb T, Wroblewski JT.
Gene 519(2):367-73. doi: 10.1016/j.gene.2013.02.009. Epub 2013 Feb 24. 2013
15GRM1
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
Martino JJ, Wall BA, Mastrantoni E, Wilimczyk BJ, La Cava SN, Degenhardt K, White E, Chen S.
Oncogene 32(37):4366-76. doi: 10.1038/onc.2012.471. Epub 2012 Oct 22. 2013
16GRM1, SCAR13
Autosomal-recessive congenital cerebellar ataxia is caused by mutations in metabotropic glutamate receptor 1.
Guergueltcheva V, Azmanov DN, Angelicheva D, Smith KR, Chamova T, Florez L, Bynevelt M, Nguyen T, Cherninkova S, Bojinova V, Kaprelyan A, Angelova L, Morar B, Chandler D, Kaneva R, Bahlo M, Tournev I, Kalaydjieva L.
Am J Hum Genet 91(3):553-64. Epub 2012 Aug 16. 2012
17GRID2, GRM1
Glutamate receptor δ2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase Cγ, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons.
Kato AS, Knierman MD, Siuda ER, Isaac JT, Nisenbaum ES, Bredt DS.
J Neurosci 32(44):15296-308. doi: 10.1523/JNEUROSCI.0705-12.2012. 2012
18GRM1, HOMER1
Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors.
Tappe-Theodor A, Fu Y, Kuner R, Neugebauer V.
Mol Pain 7:38. doi: 10.1186/1744-8069-7-38. 2011
19GRM1, GRM5
Differential distribution of group I metabotropic glutamate receptors in developing human cortex.
Boer K, Encha-Razavi F, Sinico M, Aronica E.
Brain Res 1324:24-33. Epub 2010 Feb 10.PMID: 20149785 2010
20GRM1
Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation.
Jiang Y, Huang Y, Wong HC, Zhou Y, Wang X, Yang J, Hall RA, Brown EM, Yang JJ.
J Biol Chem 285(43):33463-74. Epub 2010 Aug 12.PMID: 20705606 2010
21GRM1
The metabotropic glutamate receptor 1, GRM1: evaluation as a candidate gene for inherited forms of cerebellar ataxia.
Rossi PI, Vaccari CM, Terracciano A, Doria-Lamba L, Facchinetti S, Priolo M, Ayuso C, De Jorge L, Gimelli S, Santorelli FM, Ravazzolo R, Puliti A.
J Neurol 257(4):598-602. Epub 2009 Nov 19.PMID: 19924463 2010
22AKT2, GRM1
AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).
Shin SS, Wall BA, Goydos JS, Chen S.
Pigment Cell Melanoma Res 23(1):103-11. Epub 2009 Oct 20.PMID: 19843246 2010
23GRM1
Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway.
Francesconi A, Kumari R, Zukin RS.
J Neurosci 29(11):3590-602.PMID: 19295163 2009
24GOPC, GRASP, GRM1
A novel association of mGluR1a with the PDZ scaffold protein CAL modulates receptor activity.
Zhang J, Cheng S, Xiong Y, Ma Y, Luo D, Jeromin A, Zhang H, He J.
FEBS Lett 582(30):4117-24. Epub 2008 Nov 21. 2008
25FMR1, GRM1
Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors.
Wang H, Wu LJ, Zhang F, Zhuo M.
J Neurosci 28(17):4385-97.PMID: 18434517 2008
26GRM1
Group I metabotropic glutamate receptors control metaplasticity of spinal cord learning through a protein kinase C-dependent mechanism.
Ferguson AR, Bolding KA, Huie JR, Hook MA, Santillano DR, Miranda RC, Grau JW.
J Neurosci 28(46):11939-49.PMID: 19005059 2008
27GRM1, GRM5
Endogenous homer proteins regulate metabotropic glutamate receptor signaling in neurons.
Kammermeier PJ.
J Neurosci 28(34):8560-7.PMID: 18716215 2008
28GRM1
Transcriptional activators and repressors for the neuron-specific expression of a metabotropic glutamate receptor.
Crepaldi L, Lackner C, Corti C, Ferraguti F.
J Biol Chem 282(24):17877-89. Epub 2007 Apr 12. 2007
29GRM1
Genetic analysis of the GRM1 gene in human melanoma susceptibility.
Ortiz P, Vanaclocha F, L—pez-Bran E, Esquivias JI, L—pez-Estebaranz JL, Mart’n-Gonz‡lez M, Arrue I, Garc’a-Romero D, Ochoa C, Gonz‡lez-Perez A, Ruiz A, Real LM.
Eur J Hum Genet 15(11):1176-82. Epub 2007 Jul 4. 2007
30TRPC1, GRM1
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1.
Kim SJ, Kim YS, Yuan JP, Petralia RS, Worley PF, Linden DJ.
Nature 426(6964):285-91. Epub 2003 Nov 12. 2003
31GRM1
Assignment of the gene GRM1 coding for metabotropic glutamate receptor 1 to human chromosome band 6q24 by in situ hybridization.
Ganesh S, Amano K, Yamakawa K.
Cytogenet Cell Genet 88(3-4):314-5. No abstract available. 2000
32GRM1, GRM5, HOMER1, HOMER2, HOMER3
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors.
Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF.
Neuron 21(4):717-26 1998
33GRM1, GRM5, HOMER1, HOMER2, HOMER3
Homer: a protein that selectively binds metabotropic glutamate receptors.
Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF.
Nature 386(6622):284-8 1997
34GRM1
Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants.
Stephan D, Bon C, Holzwarth JA, Galvan M, Pruss RM.
Neuropharmacology 35(12):1649-60 1996
35GRM1
Cloning and expression of a human metabotropic glutamate receptor 1 alpha: enhanced coupling on co-transfection with a glutamate transporter.
Desai MA, Burnett JP, Mayne NG, Schoepp DD.
Mol Pharmacol 48(4):648-57 1995