1 | ETV1, GRIN2C, TIAM1
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| Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells.
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| Abe H, Okazawa M, Nakanishi S.
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| Proc Natl Acad Sci U S A 109(22):8734-9. doi: 10.1073/pnas.1206418109. Epub 2012 May 14.
2012
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2 | GRIN2C, SNX27
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| Deficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C).
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| Cai L, Loo LS, Atlashkin V, Hanson BJ, Hong W.
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| Mol Cell Biol 31(8):1734-47. Epub 2011 Feb 7.
2011
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3 | GRIN2C
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| Behavioral analysis of NR2C knockout mouse reveals deficit in acquisition of conditioned fear and working memory.
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| Hillman BG, Gupta SC, Stairs DJ, Buonanno A, Dravid SM.
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| Neurobiol Learn Mem 95(4):404-14. Epub 2011 Feb 2.
2011
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4 | GRIN2C
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| Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.
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| Chen BS, Roche KW.
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| Neuron 62(4):471-8.
2009
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5 | GRIN2A, GRIN2B, GRIN2C
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| Dual regulation of NR2B and NR2C expression by NMDA receptor activation in mouse cerebellar granule cell cultures.
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| Iijima K, Abe H, Okazawa M, Moriyoshi K, Nakanishi S.
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| Proc Natl Acad Sci U S A 105(33):12010-5. Epub 2008 Aug 6.
2008
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6 | GRIN2B, GRIN2C
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| Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels.
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| De Souza Silva MA, Dolga A, Pieri I, Marchetti L, Eisel UL, Huston JP, Dere E.
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| Genes Brain Behav 5(7):552-60.
2006
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7 | GRIN2C
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| Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation.
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| Chen BS, Braud S, Badger JD 2nd, Isaac JT, Roche KW.
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| J Biol Chem 281(24):16583-90. Epub 2006 Apr 10.
2006
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8 | GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIK1, GRIK2, GRIK3, GRIK5, GRIK4
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| NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury.
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| Salter MG, Fern R.
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| Nature 438(7071):1167-71. 2005
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9 | GRIN2A, GRIN2B, GRIN2C
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| Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.
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| Schlett K, Pieri I, Metzger F, Marchetti L, Steigerwald F, Dere E, Kirilly D, Tárnok K, Barabás B, Varga AK, Gerspach J, Huston J, Pfizenmaier K, Köhr G, Eisel UL.
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| Mol Cell Neurosci 27(3):215-26.
2004
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10 | GRIN1, GRIN2A, GRIN2B, GRIN2C
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| Evidence relating human verbal memory to hippocampal N-methyl-D-aspartate receptors.
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| Grunwald T, Beck H, Lehnertz K, Blumcke I, Pezer N, Kurthen M, Fernandez G, Van Roost D, Heinze HJ, Kutas M, Elger CE.
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| Proc Natl Acad Sci U S A 96(21):12085-9. 1999
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11 | GRIN2A, GRIN2C, GRIN2D
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| Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.
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| Kalsi G, Whiting P, Bourdelles BL, Callen D, Barnard EA, Gurling H.
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| Genomics 47(3):423-5. 1998
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12 | GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D
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| Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus.
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| Kosinski CM, et al.
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| J Comp Neurol 390(1):63-74 1998
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13 | GRIN2A, GRIN2B, GRIN2C
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| Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.
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| Sprengel R, Suchanek B, Amico C, Brusa R, Burnashev N, Rozov A, Hvalby O, Jensen V, Paulsen O, Andersen P, Kim JJ, Thompson RF, Sun W, Webster LC, Grant SG, Eilers J, Konnerth A, Li J, McNamara JO, Seeburg PH.
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| Cell 92(2):279-89. 1998
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14 | GRIN2C
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| The human N-methyl-D-aspartate receptor 2C subunit: genomic analysis, distribution in human brain, and functional expression.
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| Daggett LP, Johnson EC, Varney MA, Lin FF, Hess SD, Deal CR, Jachec C, Lu CC, Kerner JA, Landwehrmeyer GB, Standaert DG, Young AB, Harpold MM, Velicelebi G.
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| J Neurochem 71(5):1953-68. 1998
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15 | GRIN2C, NRG1
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| Neuregulin-beta induces expression of an NMDA-receptor subunit.
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| Ozaki M, Sasner M, Yano R, Lu HS, Buonanno A.
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| Nature 390(6661):691-4. 1997
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16 | GRIN2C
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| Cloning of the cDNA for the human NMDA receptor NR2C subunit and its expression in the central nervous system and periphery.
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| Lin YJ, et al.
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| Brain Res Mol Brain Res 43 : 57-64. 1996
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17 | GRIN2A, GRIN2C
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| Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit.
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| Kadotani H, Hirano T, Masugi M, Nakamura K, Nakao K, Katsuki M, Nakanishi S.
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| J Neurosci 16(24):7859-67. 1996
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18 | GRIN1, GRIN2A, GRIN2C
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| Chromosomal localization of the epsilon 1, epsilon 3 and dzta 1 subunit genes of the human NMDA receptor channel.
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| Takano H, et al.
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| Biochem Biophys Res Commun 197 : 922-926. 1993
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