Citations for
1GRIA1, GRIK3, GRIN1, GRIN2B
The association between eating behavior and polymorphisms in GRIN2B, GRIK3, GRIA1 and GRIN1 genes in people with type 2 diabetes mellitus
Kochetova OV, Avzaletdinova DS, Korytina GF, Morugova TV, Mustafina OE.
Mol Biol Rep. Mar;47(3):2035-2046. doi: 10.1007/s11033-020-05304-x. Epub 2020 Feb 10. 2020
2FRMPD2, GRIN2A, GRIN2B
The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors
Lu X, Zhang Q, Wang T.
Biochem Biophys Res Commun. Aug 13;516(1):63-67. doi: 10.1016/j.bbrc.2019.05.087. Epub 2019 Jun 10 2019
3ARF6, GRIN2B, IQSEC2
Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation.
Elagabani MN, Briševac D, Kintscher M, Pohle J, Köhr G, Schmitz D, Kornau HC.
J Biol Chem 291(17):9105-18. doi: 10.1074/jbc.M115.691717. Epub 2016 Feb 16. 2016
4GRIN2A, GRIN2B, TSPYL2
The nucleosome assembly protein TSPYL2 regulates the expression of NMDA receptor subunits GluN2A and GluN2B.
Tsang KH, Lai SK, Li Q, Yung WH, Liu H, Mak PH, Ng CC, McAlonan G, Chan YS, Chan SY.
Sci Rep 4:3654. doi: 10.1038/srep03654. 2014
5GRIN1, GRIN2B
Crystal structure of a heterotetrameric NMDA receptor ion channel.
Karakas E, Furukawa H.
Science 344(6187):992-7. doi: 10.1126/science.1251915. 2014
6EIEE27, GRIN2B
GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.
Lemke JR, Hendrickx R, Geider K, Laube B, Schwake M, Harvey RJ, James VM, Pepler A, Steiner I, Hörtnagel K, Neidhardt J, Ruf S, Wolff M, Bartholdi D, Caraballo R, Platzer K, Suls A, De Jonghe P, Biskup S, Weckhuysen S.
Ann Neurol 75(1):147-54. doi: 10.1002/ana.24073. Epub 2014 Jan 2. 2014
7GRIN2B, GRIN2D
Opposing role of NMDA receptor GluN2B and GluN2D in somatosensory development and maturation.
Yamasaki M, Okada R, Takasaki C, Toki S, Fukaya M, Natsume R, Sakimura K, Mishina M, Shirakawa T, Watanabe M.
J Neurosci 34(35):11534-48. doi: 10.1523/JNEUROSCI.1811-14.2014. 2014
8GRIN2B, GRIN2D
NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina.
Bai N, Aida T, Yanagisawa M, Katou S, Sakimura K, Mishina M, Tanaka K.
Mol Brain 6:34. doi: 10.1186/1756-6606-6-34. 2013
9DLG4, GRIN2A, GRIN2B
Identification of N-methyl-D-aspartic acid (NMDA) receptor subtype-specific binding sites that mediate direct interactions with scaffold protein PSD-95.
Cousins SL, Stephenson FA.
J Biol Chem 287(16):13465-76. doi: 10.1074/jbc.M111.292862. Epub 2012 Feb 28. 2012
10FOXP1, GRIN2B, LAMC3, SCN1A
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations.
O'Roak BJ, Deriziotis P, Lee C, Vives L, Schwartz JJ, Girirajan S, Karakoc E, Mackenzie AP, Ng SB, Baker C, Rieder MJ, Nickerson DA, Bernier R, Fisher SE, Shendure J, Eichler EE.
Nat Genet 43(6):585-9. Epub 2011 May 15. 2011
11GRIN2A, GRIN2B
Mutations in NMDA receptors influence neurodevelopmental disorders causing epilepsy and intellectual disability.
Metzler M.
Clin Genet 79(3):219-20. doi: 10.1111/j.1399-0004.2010.01610.x. Epub 2011 Jan 4. No abstract available. 2011
12GRIN2B, KALRN
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Kiraly DD, Lemtiri-Chlieh F, Levine ES, Mains RE, Eipper BA.
J Neurosci 31(35):12554-65. 2011
13GRIN1, GRIN2B, GRIN2D
NMDA receptor subunit expression in the supraoptic nucleus of adult rats: dominance of NR2B and NR2D.
Doherty FC, Sladek CD.
Brain Res 1388:89-99. doi: 10.1016/j.brainres.2011.03.015. 2011
14GRIN2A, GRIN2B, KIF17
Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels.
Yin X, Takei Y, Kido MA, Hirokawa N.
Neuron 70(2):310-25. doi: 10.1016/j.neuron.2011.02.049. 2011
15GRIN1, GRIN2B, KIF17, NRF1
The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons.
Dhar SS, Wong-Riley MT.
Biochim Biophys Acta 1813(3):403-11. doi: 10.1016/j.bbamcr.2010.12.013. Epub 2010 Dec 21. 2011
16DAPK1, GRIN2B
DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke.
Tu W, Xu X, Peng L, Zhong X, Zhang W, Soundarapandian MM, Balel C, Wang M, Jia N, Zhang W, Lew F, Chan SL, Chen Y, Lu Y.
Cell 140(2):222-234.PMID: 20141836 2010
17GRIN2B, MTOR
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS.
Science 329(5994):959-64. 2010
18CACNG2, CACNG2, CNIH, CNIH2, CNIH3, CNIH4, GRIA1, GRIA2, GRIA3, GRIN2B
Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.
Shi Y, Suh YH, Milstein AD, Isozaki K, Schmid SM, Roche KW, Nicoll RA.
Proc Natl Acad Sci U S A 107(37):16315-9. Epub 2010 Aug 30.PMID: 20805473 2010
19GRIN2A, GRIN2B
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, Milh M, Kortüm F, Fritsch A, Pientka FK, Hellenbroich Y, Kalscheuer VM, Kohlhase J, Moog U, Rappold G, Rauch A, Ropers HH, von Spiczak S, Tönnies H, Villeneuve N, Villard L, Zabel B, Zenker M, Laube B, Reis A, Wieczorek D, Van Maldergem L, Kutsche K.
Nat Genet 42(11):1021-6. Epub 2010 Oct 3. 2010
20EPND, GRIN2A, GRIN2B, MRD6
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, Milh M, Kortüm F, Fritsch A, Pientka FK, Hellenbroich Y, Kalscheuer VM, Kohlhase J, Moog U, Rappold G, Rauch A, Ropers HH, von Spiczak S, Tönnies H, Villeneuve N, Villard L, Zabel B, Zenker M, Laube B, Reis A, Wieczorek D, Van Maldergem L, Kutsche K.
Nat Genet 42(11):1021-6. doi: 10.1038/ng.677. Epub 2010 Oct 3. 2010
21CASK, GRIN2B, TAF9
CASK point mutation regulates protein-protein interactions and NR2b promoter activity.
Huang TN, Hsueh YP.
Biochem Biophys Res Commun 382(1):219-22. Epub 2009 Mar 9. 2009
22APOE, COMT, DAO, DRD1, DRD2, DRD4, DTNBP1, GABRB2, GRIN2B, HP, IL1B, MTHFR, PLXNA2, SCZD23, SLC6A4, TP53, TPH1
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.
Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L.
Nat Genet 40(7):827-34. 2008
23GRIN2A, GRIN2B, GRIN2C
Dual regulation of NR2B and NR2C expression by NMDA receptor activation in mouse cerebellar granule cell cultures.
Iijima K, Abe H, Okazawa M, Moriyoshi K, Nakanishi S.
Proc Natl Acad Sci U S A 105(33):12010-5. Epub 2008 Aug 6. 2008
24GRIN2B
Association study between the NMDA receptor 2B subunit gene (GRIN2B) and schizophrenia: a HuGE review and meta-analysis.
Li D, He L.
Genet Med 9(1):4-8. 2007
25GRIN2B, CDK5
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation.
Hawasli AH, Benavides DR, Nguyen C, Kansy JW, Hayashi K, Chambon P, Greengard P, Powell CM, Cooper DC, Bibb JA.
Nat Neurosci 10(7):880-6. Epub 2007 May 27. 2007
26GRIN2B, GRIN2C
Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels.
De Souza Silva MA, Dolga A, Pieri I, Marchetti L, Eisel UL, Huston JP, Dere E.
Genes Brain Behav 5(7):552-60. 2006
27GRIN1, GRIN2B
An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray.
Qin S, Zhao X, Pan Y, Liu J, Feng G, Fu J, Bao J, Zhang Z, He L.
Eur J Hum Genet 13(7):807-14. 2005
28GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIK1, GRIK2, GRIK3, GRIK5, GRIK4
NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury.
Salter MG, Fern R.
Nature 438(7071):1167-71. 2005
29GRIN2B
Microtubule regulation of N-methyl-D-aspartate receptor channels in neurons.
Yuen EY, Jiang Q, Feng J, Yan Z.
J Biol Chem 280(33):29420-7. Epub 2005 Jun 23. 2005
30GRIN1, GRIN2B
Human T lymphocytes express N-methyl-D-aspartate receptors functionally active in controlling T cell activation.
Miglio G, Varsaldi F, Lombardi G.
Biochem Biophys Res Commun 338(4):1875-83. Epub 2005 Nov 9. 2005
31GRIN2A, GRIN2B, GRIN2C
Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.
Schlett K, Pieri I, Metzger F, Marchetti L, Steigerwald F, Dere E, Kirilly D, Tárnok K, Barabás B, Varga AK, Gerspach J, Huston J, Pfizenmaier K, Köhr G, Eisel UL.
Mol Cell Neurosci 27(3):215-26. 2004
32GRIN2B, GRIN2D
Molecular identification of NMDA glutamate receptors expressed in bone cells.
Itzstein C, Cheynel H, Burt-Pichat B, Merle B, Espinosa L, Delmas PD, Chenu C.
J Cell Biochem 82(1):134-44. 2001
33GRIN1, GRIN2A, GRIN2B, GRIN2C
Evidence relating human verbal memory to hippocampal N-methyl-D-aspartate receptors.
Grunwald T, Beck H, Lehnertz K, Blumcke I, Pezer N, Kurthen M, Fernandez G, Van Roost D, Heinze HJ, Kutas M, Elger CE.
Proc Natl Acad Sci U S A 96(21):12085-9. 1999
34GRIN2B
Genetic enhancement of learning and memory in mice.
Tang YP, Shimizu E, Dube GR, Rampon C, Kerchner GA, Zhuo M, Liu G, Tsien JZ.
Nature 401(6748):63-9. 1999
35GRIN2A, GRIN2B
Glutamate receptor mechanisms in human epileptic dysplastic cortex.
Babb TL, et al.
Epilepsy Res 32 : 24-33. 1998
36GRIN1, GRIN2A, GRIN2B
Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex.
Scherzer CR, et al.
J Comp Neurol 390(1):75-90 1998
37GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D
Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus.
Kosinski CM, et al.
J Comp Neurol 390(1):63-74 1998
38GRIN2A, GRIN2B, GRIN2C
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.
Sprengel R, Suchanek B, Amico C, Brusa R, Burnashev N, Rozov A, Hvalby O, Jensen V, Paulsen O, Andersen P, Kim JJ, Thompson RF, Sun W, Webster LC, Grant SG, Eilers J, Konnerth A, Li J, McNamara JO, Seeburg PH.
Cell 92(2):279-89. 1998
39GRIN2B
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice.
Kutsuwada T, Sakimura K, Manabe T, Takayama C, Katakura N, Kushiya E, Natsume R, Watanabe M, Inoue Y, Yagi T, Aizawa S, Arakawa M, Takahashi T, Nakamura Y, Mori H, Mishina M.
Neuron 16(2):333-44. 1996
40GRIN2B
Human N-methyl-D-aspartate receptor modulatory subunit hNR3: cloning and sequencing of the cDNA and primary structure of the protein.
Adams SL, Foldes RL, Kamboj RK.
Biochim Biophys Acta 1260(1):105-8. 1995
41GRIN2B
Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12.
Mandich P, et al.
Genomics 22 : 216-218. 1994