| 1 | GRIK2, MRT6
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| Clustered mutations in the GRIK2 kainate receptor subunit gene underlie diverse neurodevelopmental disorders
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| Stolz JR, Foote KM, Veenstra-Knol HE, Pfundt R, Ten Broeke SW, de Leeuw N, Roht L, Pajusalu S, Part R, Rebane I, Õunap K, Stark Z, Kirk EP, Lawson JA, Lunke S, Christodoulou J, Louie RJ, Rogers RC, Davis JM, Innes AM, Wei XC, Keren B, Mignot C, Lebel RR, Sperber SM, Sakonju A, Dosa N, Barge-Schaapveld DQCM, Peeters-Scholte CMPCD, Ruivenkamp CAL, van Bon BW, Kennedy J, Low KJ, Ellard S, Pang L, Junewick JJ, Mark PR, Carvill GL, Swanson GT
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| Am J Hum Genet. Sep 2;108(9):1692-1709. doi: 10.1016/j.ajhg.2021.07.007. Epub 2021 Aug 9. 2021
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| 2 | GRIK2, TTBK2
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| Tau Tubulin Kinase TTBK2 Sensitivity of Glutamate Receptor GluK2.
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| Nieding K, Matschke V, Meuth SG, Lang F, Seebohm G, Strutz-Seebohm N.
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| Cell Physiol Biochem 39(4):1444-52. doi: 10.1159/000447847. Epub 2016 Sep 9.
2016
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| 3 | GRIK2, NDRG2, SGK1
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| NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes.
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| Matschke V, Theiss C, Hollmann M, Schulze-Bahr E, Lang F, Seebohm G, Strutz-Seebohm N.
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| Front Cell Neurosci 9:387. doi: 10.3389/fncel.2015.00387. eCollection 2015.
2015
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| 4 | EPB41L1, GRIK1, GRIK2
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| Kainate receptor post-translational modifications differentially regulate association with 4.1N to control activity-dependent receptor endocytosis.
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| Copits BA, Swanson GT.
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| J Biol Chem 288(13):8952-65. doi: 10.1074/jbc.M112.440719. Epub 2013 Feb 11.
2013
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| 5 | GRIK1, GRIK2, GRIK3, GRIK4, GRIK5
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| Developmental expression patterns of kainate receptors in the mouse spinal cord.
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| Cui S, Du P, Zhou X, Wang H.
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| Neuroreport 23(17):1012-6. doi: 10.1097/WNR.0b013e32835a7f1e.
2012
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| 6 | CFS, GRIK2
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| Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome.
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| Smith AK, Fang H, Whistler T, Unger ER, Rajeevan MS.
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| Neuropsychobiology 64(4):183-94. doi: 10.1159/000326692.
2011
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| 7 | GRIK2, GRIK5
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| Distinct functional roles of subunits within the heteromeric kainate receptor.
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| Fisher JL, Mott DD.
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| J Neurosci 31(47):17113-22. doi: 10.1523/JNEUROSCI.3685-11.2011.
2011
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| 8 | GRIK2
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| Novel spliced variants of ionotropic glutamate receptor GluR6 in normal human fibroblast and brain cells are transcribed by tissue specific promoters.
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| Zhawar VK, Kaur G, deRiel JK, Kaur GP, Kandpal RP, Athwal RS.
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| Gene 459(1-2):1-10. Epub 2010 Mar 15.
2010
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| 9 | GRIK2, RELN
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| Linkage and candidate gene studies of autism spectrum disorders in European populations.
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| Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojärvi K, Järvelä I, Klauck SM, Poustka F, Bailey AJ, Monaco AP.
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| Eur J Hum Genet ur J Hum Genet. 2010 May 5. [Epub ahead of print]PMID: 20442744 2010
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| 10 | GRIK2
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| Association Between Polymorphisms in GRIK2 Gene and Obsessive-Compulsive Disorder: A Family-Based Study.
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| Sampaio AS, Fagerness J, Crane J, Leboyer M, Delorme R, Pauls DL, Stewart SE.
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| CNS Neurosci Ther NS Neurosci Ther. 2010 Mar 29. [Epub ahead of print]PMID: 20370803 2010
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| 11 | GRIK2
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| Differential regulation of kainate receptor trafficking by phosphorylation of distinct sites on GluR6.
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| Nasu-Nishimura Y, Jaffe H, Isaac JT, Roche KW.
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| J Biol Chem 285(4):2847-56. Epub 2009 Nov 17.PMID: 19920140 2010
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| 12 | GRIK2
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| Domain organization and function in GluK2 subtype kainate receptors.
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| Das U, Kumar J, Mayer ML, Plested AJ.
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| Proc Natl Acad Sci U S A 107(18):8463-8. Epub 2010 Apr 19.PMID: 20404149 2010
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| 13 | auts18, grik2
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| Holt R, Barnby G, Maestrini E, Bacchelli E, Brocklebank D, Sousa I, Mulder EJ, Kantojärvi K, Järvelä I, Klauck SM, Poustka F, Bailey AJ, Monaco AP; EU Autism MOLGEN Consortium
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| Linkage and candidate gene studies of autism spectrum disorders in European populations.
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| Eur J Hum Genet 18(9):1013-9. 2010
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| 14 | GRIK2
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| Human GluR6c, a functional splicing variants of GluR6, is mainly expressed in non-nervous cells.
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| Barbon A, Gervasoni A, LaVia L, Orlandi C, Jaskolski F, Perrais D, Barlati S.
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| Neurosci Lett 434(1):77-82. Epub 2008 Feb 2.PMID: 18289788 2008
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| 15 | GRIK2
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| Identification of C-terminal domain residues involved in protein kinase A-mediated potentiation of kainate receptor subtype 6.
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| Kornreich BG, Niu L, Roberson MS, Oswald RE.
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| Neuroscience 146(3):1158-68. Epub 2007 Mar 26. 2007
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| 16 | GRIK2, MRT6
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| A Defect in the Ionotropic Glutamate Receptor 6 Gene (GRIK2) Is Associated with Autosomal Recessive Mental Retardation.
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| Motazacker MM, Rost BR, Hucho T, Garshasbi M, Kahrizi K, Ullmann R, Abedini SS, Nieh SE, Amini SH, Goswami C, Tzschach A, Jensen LR, Schmitz D, Ropers HH, Najmabadi H, Kuss AW.
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| Am J Hum Genet 81(4):792-8. Epub 2007 Aug 31. 2007
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| 17 | GRIK1, GRIK2, GRIK5, KIF17
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| Localization of glutamate receptors to distal dendrites depends on subunit composition and the kinesin motor protein KIF17.
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| Kayadjanian N, Lee HS, Piña-Crespo J, Heinemann SF.
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| Mol Cell Neurosci 34(2):219-30. Epub 2006 Dec 15.
2007
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| 18 | GRIK2, KLHL24, PICK1
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| KRIP6: a novel BTB/kelch protein regulating function of kainate receptors.
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| Laezza F, Wilding TJ, Sequeira S, Coussen F, Zhang XZ, Hill-Robinson R, Mulle C, Huettner JE, Craig AM.
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| Mol Cell Neurosci 34(4):539-50. Epub 2007 Jan 24. 2007
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| 19 | GRIK2
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| SUMOylation regulates kainate-receptor-mediated synaptic transmission.
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| Martin S, Nishimune A, Mellor JR, Henley JM.
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| Nature 447(7142):321-5. Epub 2007 May 7.PMID: 17486098 2007
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| 20 | GRIK2, KLHL17
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| Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway.
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| Salinas GD, Blair LA, Needleman LA, Gonzales JD, Chen Y, Li M, Singer JD, Marshall J.
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| J Biol Chem 281(52):40164-73. Epub 2006 Oct 24.
2006
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| 21 | GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, GRIK1, GRIK2, GRIK3, GRIK5, GRIK4
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| NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury.
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| Salter MG, Fern R.
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| Nature 438(7071):1167-71. 2005
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| 22 | GRIK2
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| Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
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| Breustedt J, Schmitz D.
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| J Neurosci 24(45):10093-8. 2004
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| 23 | AUTS18, GRIK2
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| Linkage and association of the glutamate receptor 6 gene with autism.
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| Jamain S, Betancur C, Quach H, Philippe A, Fellous M, Giros B, Gillberg C, Leboyer M, Bourgeron T; Paris Autism Research International Sibpair (PARIS) Study.
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| Mol Psychiatry 7(3):302-10. 2002
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| 24 | GRIK2
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| Genomic organization of the human GRIK2 gene and evidence for multiple splicing variants.
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| Barbon A, Vallini I, Barlati S.
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| Gene 274(1-2):187-97. 2001
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| 25 | GRIK2
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| Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.
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| Contractor A, Swanson G, Heinemann SF.
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| Neuron 29(1):209-16.PMID: 11182092 2001
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| 26 | GRIK2
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| Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease.
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| Rubinsztein DC, Leggo J, Chiano M, Dodge A, Norbury G, Rosser E, Craufurd D.
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| Proc Natl Acad Sci U S A 94(8):3872-6.PMID: 9108071 1997
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| 27 | GRIK2
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| Refinement of map position of the human GluR6 kainate receptor gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsies.
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| Sander T, et al.
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| Neurology 45 : 1713-1720. 1995
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| 28 | GRIK2
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| Human GluR6 kainate receptor (GRIK2) : molecular cloning, expression, polymorphism, and chromosomal assignment.
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| Paschen W, et al.
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| Genomics 20 : 435-440. 1994
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