Citations for
1GRB10
Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.
Mokbel N, Hoffman NJ, Girgis CM, Small L, Turner N, Daly RJ, Cooney GJ, Holt LJ.
J Cell Physiol 229(11):1753-64. doi: 10.1002/jcp.24628. 2014
2GRB10, GRB14, GRB7
Grb10 is a dual regulator of receptor tyrosine kinase signaling.
Kabir NN, Kazi JU.
Mol Biol Rep 41(4):1985-92. doi: 10.1007/s11033-014-3046-4. Review. 2014
3GRB10, LMX1A, RGS4
Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.
Hoekstra EJ, von Oerthel L, van der Linden AJ, Schellevis RD, Scheppink G, Holstege FC, Groot-Koerkamp MJ, van der Heide LP, Smidt MP.
Eur J Neurosci 37(1):23-32. doi: 10.1111/ejn.12022. Epub 2012 Oct 29. 2013
4GRB10
Heterogeneous growth patterns in carriers of chromosome 7p12.2 imbalances affecting GRB10.
Eggermann T, Begemann M, Gogiel M, Palomares M, Vallespín E, Fernández L, Cazorla R, Spengler S, García-Miñaúr S.
Am J Med Genet A m J Med Genet A. 2012 Sep 17. doi: 10.1002/ajmg.a.35612. [Epub ahead of print] 2012
5GRB10
Epigenetic modifications and mRNA levels of the imprinted gene Grb10 in serially passaged fibroblast cells.
Yao J, Huang Y, Huang R, Shi R, Chen P, Zhu B, Li M, Jiang X, Zheng M, Jiang Y, Yang X.
Biochimie iochimie. 2012 Aug 21. [Epub ahead of print] 2012
6GRB10
Grb10 regulates the development of fiber number in skeletal muscle.
Holt LJ, Turner N, Mokbel N, Trefely S, Kanzleiter T, Kaplan W, Ormandy CJ, Daly RJ, Cooney GJ.
FASEB J 26(9):3658-69. Epub 2012 May 23. 2012
7GRB10
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.
Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villén J, Kubica N, Hoffman GR, Cantley LC, Gygi SP, Blenis J.
Science 332(6035):1322-6. 2011
8GRB10
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, Gilroy K, Baker S, Xia J, Dalley JW, Hurst LD, Wilkinson LS, Isles AR, Ward A.
Nature 469(7331):534-8. 2011
9GRB10, NEDD4
Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4.
Huang Q, Szebenyi DM.
J Biol Chem 285(53):42130-9. Epub 2010 Oct 26. 2010
10BCL2L11, GRB10
Grb10 interacts with Bim L and inhibits apoptosis.
Hu ZQ, Zhang JY, Ji CN, Xie Y, Chen JZ, Mao YM.
Mol Biol Rep 37(7):3547-52. Epub 2010 Feb 20. 2010
11GRB10
Maternally-inherited Grb10 reduces placental size and efficiency.
Charalambous M, Cowley M, Geoghegan F, Smith FM, Radford EJ, Marlow BP, Graham CF, Hurst LD, Ward A.
Dev Biol 337(1):1-8. Epub 2009 Oct 13. 2010
12GRB10, SRS7
Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation.
Shiura H, Nakamura K, Hikichi T, Hino T, Oda K, Suzuki-Migishima R, Kohda T, Kaneko-Ishino T, Ishino F.
Hum Mol Genet 18(8):1424-1438 . [Epub 2009 Jan 27] 2009
13GRB10
Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression.
Monk D, Arnaud P, Frost J, Hills FA, Stanier P, Feil R, Moore GE.
Hum Mol Genet 18(16):3066-74. Epub 2009 Jun 1.PMID: 19487367 2009
14GRB10, GRB14
Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14.
Depetris RS, Wu J, Hubbard SR.
Nat Struct Mol Biol 16(8):833-9. Epub 2009 Aug 2. Erratum in: Nat Struct Mol Biol. 2009 Dec;16(12):1331. 2009
15GRB10, GRB14
Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.
Holt LJ, Lyons RJ, Ryan AS, Beale SM, Ward A, Cooney GJ, Daly RJ.
Mol Endocrinol 23(9):1406-14. Epub 2009 Jun 18. 2009
16BWS, GNASAS, GRB10, HILS, KCNQ1OT1, PEG1/MEST, PEG3, TNDM, ZAC, ZFP57
Clinical characterisation of the multiple maternal hypomethylation syndrome in siblings.
Boonen SE, Pörksen S, Mackay DJ, Oestergaard E, Olsen B, Brondum-Nielsen K, Temple IK, Hahnemann JM.
Eur J Hum Genet 16(4):453-61. Epub 2008 Jan 16. 2008
17GRB10, LRP6
GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.
Tezuka N, Brown AM, Yanagawa S.
Biochem Biophys Res Commun 356(3):648-54. Epub 2007 Mar 12. 2007
18GRB10, MEST, SRS7
Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays.
Kim Y, Kim SS, Kim G, Park S, Park IS, Yoo HW.
Clin Genet 67(3):267-9. No abstract available. 2005
19GRB10
Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites.
Hikichi T, Kohda T, Kaneko-Ishino T, Ishino F.
Nucleic Acids Res 31(5):1398-406. 2003
20UPD7M, SRS7, GRB10
Do patients with maternal uniparental disomy for chromosome 7 have a distinct mild Silver-Russell phenotype?
Hannula K, Kere J, Pirinen S, Holmberg C, Lipsanen-Nyman M.
J Med Genet 38 : 273-278. 2001
21GRB10, SRS7, COPG2, UPD7M
A narrow segment of maternal uniparental disomy of chromosome 7q31-qter in Silver-Russell syndrome delimits a candidate gene region.
Hannula K, Lipsanen-Nyman M, Kontiokari T, Kere J.
Am J Hum Genet 68(1):247-53. 2001
22GRB10
Maternal repression of the human GRB10 gene in the developing central nervous system; evaluation of the role for GRB10 in Silver-Russell syndrome.
Hitchins MP, Monk D, Bell GM, Ali Z, Preece MA, Stanier P, Moore GE.
Eur J Hum Genet 9(2):82-90. 2001
23GRB10, MEST, NOS3, SERPINE1, UPD7M
Maternal and paternal chromosomes 7 show differential methylation of many genes in lymphoblast DNA.
Hannula K, Lipsanen-Nyman M, Scherer SW, Holmberg C, Hoglund P, Kere J.
Genomics 73(1):1-9. 2001
24GRB10, GRB14, GRB7
The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions.
Han DC, Shen TL, Guan JL.
Oncogene 20(44):6315-21. Review. 2001
25DUP7PP, GRB10, SRS7, UPD7M
Duplication of 7p11.2-p13, including GRB10, in Silver-Russell syndrome.
Monk D, Wakeling EL, Proud V, Hitchins M, Abu-Amero SN, Stanier P, Preece MA, Moore GE.
Am J Hum Genet 66(1):36-46. 2000
26GRB10
Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion.
Blagitko N, Mergenthaler S, Schulz U, Wollmann HA, Craigen W, Eggermann T, Ropers HH, Kalscheuer VM.
Hum Mol Genet 9(11):1587-95. 2000
27GRB10, SRS7, UPD7M
Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome.
Yoshihashi H, Maeyama K, Kosaki R, Ogata T, Tsukahara M, Goto Y, Hata J, Matsuo N, Smith RJ, Kosaki K.
Am J Hum Genet 67(2):476-82. Epub 2000 Jun 12. 2000
28DUP7PP, GRB10, SRS7
Duplication of 7p12.1-p13, including GRB10 and IGFBP1, in a mother and daughter with features of Silver-Russell syndrome.
Joyce CA, Sharp A, Walker JM, Bullman H, Temple IK.
Hum Genet 105(3):273-80. 1999
29GRB10
Genomic structure of the gene for the SH2 and pleckstrin homology domain-containing protein GRB10 and evaluation of its role in Hirschsprung disease.
Angrist M, et al.
Oncogene 17 : 3065-3070. 1998
30GRB10
Assignment of growth factor receptor-bound protein 10 (GRB10) to human chromosome 7p11.2-p12.
Jerome CA, et al.
Genomics 40 : 215-216. 1997
31GRB10
Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma.
Dong LQ, Du H, Porter SG, Kolakowski LF Jr, Lee AV, Mandarino LJ, Fan J, Yee D, Liu F.
J Biol Chem 272(46):29104-12. 1997
32GRB10
Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.
Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE.
J Biol Chem 272(5):2659-67. 1997
33GRB10
Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling.
O'Neill TJ, Rose DW, Pillay TS, Hotta K, Olefsky JM, Gustafson TA.
J Biol Chem 271(37):22506-13. 1996
34GRB10
The cloning of Grb10 reveals a new family of SH2 domain proteins.
Ooi J, et al.
Oncogene 10 : 1621-1630. 1995
35GRB10
The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10.
Pandey A, Duan H, Di Fiore PP, Dixit VM.
J Biol Chem 270(37):21461-3. 1995
36GRB10
Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.
Liu F, Roth RA.
Proc Natl Acad Sci U S A 92(22):10287-91. 1995