| 1 | GRB10
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| Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.
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| Mokbel N, Hoffman NJ, Girgis CM, Small L, Turner N, Daly RJ, Cooney GJ, Holt LJ.
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| J Cell Physiol 229(11):1753-64. doi: 10.1002/jcp.24628.
2014
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| 2 | GRB10, GRB14, GRB7
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| Grb10 is a dual regulator of receptor tyrosine kinase signaling.
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| Kabir NN, Kazi JU.
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| Mol Biol Rep 41(4):1985-92. doi: 10.1007/s11033-014-3046-4. Review.
2014
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| 3 | GRB10, LMX1A, RGS4
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| Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.
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| Hoekstra EJ, von Oerthel L, van der Linden AJ, Schellevis RD, Scheppink G, Holstege FC, Groot-Koerkamp MJ, van der Heide LP, Smidt MP.
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| Eur J Neurosci 37(1):23-32. doi: 10.1111/ejn.12022. Epub 2012 Oct 29.
2013
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| 4 | GRB10
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| Heterogeneous growth patterns in carriers of chromosome 7p12.2 imbalances affecting GRB10.
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| Eggermann T, Begemann M, Gogiel M, Palomares M, Vallespín E, Fernández L, Cazorla R, Spengler S, García-Miñaúr S.
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| Am J Med Genet A m J Med Genet A. 2012 Sep 17. doi: 10.1002/ajmg.a.35612. [Epub ahead of print]
2012
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| 5 | GRB10
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| Epigenetic modifications and mRNA levels of the imprinted gene Grb10 in serially passaged fibroblast cells.
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| Yao J, Huang Y, Huang R, Shi R, Chen P, Zhu B, Li M, Jiang X, Zheng M, Jiang Y, Yang X.
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| Biochimie iochimie. 2012 Aug 21. [Epub ahead of print]
2012
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| 6 | GRB10
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| Grb10 regulates the development of fiber number in skeletal muscle.
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| Holt LJ, Turner N, Mokbel N, Trefely S, Kanzleiter T, Kaplan W, Ormandy CJ, Daly RJ, Cooney GJ.
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| FASEB J 26(9):3658-69. Epub 2012 May 23.
2012
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| 7 | GRB10
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| Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.
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| Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villén J, Kubica N, Hoffman GR, Cantley LC, Gygi SP, Blenis J.
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| Science 332(6035):1322-6.
2011
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| 8 | GRB10
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| Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
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| Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, Gilroy K, Baker S, Xia J, Dalley JW, Hurst LD, Wilkinson LS, Isles AR, Ward A.
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| Nature 469(7331):534-8.
2011
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| 9 | GRB10, NEDD4
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| Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4.
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| Huang Q, Szebenyi DM.
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| J Biol Chem 285(53):42130-9. Epub 2010 Oct 26.
2010
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| 10 | BCL2L11, GRB10
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| Grb10 interacts with Bim L and inhibits apoptosis.
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| Hu ZQ, Zhang JY, Ji CN, Xie Y, Chen JZ, Mao YM.
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| Mol Biol Rep 37(7):3547-52. Epub 2010 Feb 20.
2010
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| 11 | GRB10
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| Maternally-inherited Grb10 reduces placental size and efficiency.
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| Charalambous M, Cowley M, Geoghegan F, Smith FM, Radford EJ, Marlow BP, Graham CF, Hurst LD, Ward A.
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| Dev Biol 337(1):1-8. Epub 2009 Oct 13.
2010
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| 12 | GRB10, SRS7
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| Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation.
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| Shiura H, Nakamura K, Hikichi T, Hino T, Oda K, Suzuki-Migishima R, Kohda T, Kaneko-Ishino T, Ishino F.
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| Hum Mol Genet 18(8):1424-1438 . [Epub 2009 Jan 27] 2009
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| 13 | GRB10
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| Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression.
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| Monk D, Arnaud P, Frost J, Hills FA, Stanier P, Feil R, Moore GE.
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| Hum Mol Genet 18(16):3066-74. Epub 2009 Jun 1.PMID: 19487367 2009
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| 14 | GRB10, GRB14
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| Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14.
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| Depetris RS, Wu J, Hubbard SR.
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| Nat Struct Mol Biol 16(8):833-9. Epub 2009 Aug 2. Erratum in: Nat Struct Mol Biol. 2009 Dec;16(12):1331.
2009
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| 15 | GRB10, GRB14
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| Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.
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| Holt LJ, Lyons RJ, Ryan AS, Beale SM, Ward A, Cooney GJ, Daly RJ.
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| Mol Endocrinol 23(9):1406-14. Epub 2009 Jun 18.
2009
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| 16 | BWS, GNASAS, GRB10, HILS, KCNQ1OT1, PEG1/MEST, PEG3, TNDM, ZAC, ZFP57
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| Clinical characterisation of the multiple maternal hypomethylation syndrome in siblings.
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| Boonen SE, Pörksen S, Mackay DJ, Oestergaard E, Olsen B, Brondum-Nielsen K, Temple IK, Hahnemann JM.
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| Eur J Hum Genet 16(4):453-61. Epub 2008 Jan 16. 2008
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| 17 | GRB10, LRP6
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| GRB10 binds to LRP6, the Wnt co-receptor and inhibits canonical Wnt signaling pathway.
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| Tezuka N, Brown AM, Yanagawa S.
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| Biochem Biophys Res Commun 356(3):648-54. Epub 2007 Mar 12. 2007
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| 18 | GRB10, MEST, SRS7
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| Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays.
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| Kim Y, Kim SS, Kim G, Park S, Park IS, Yoo HW.
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| Clin Genet 67(3):267-9. No abstract available. 2005
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| 19 | GRB10
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| Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites.
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| Hikichi T, Kohda T, Kaneko-Ishino T, Ishino F.
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| Nucleic Acids Res 31(5):1398-406. 2003
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| 20 | UPD7M, SRS7, GRB10
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| Do patients with maternal uniparental disomy for chromosome 7 have a distinct mild Silver-Russell phenotype?
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| Hannula K, Kere J, Pirinen S, Holmberg C, Lipsanen-Nyman M.
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| J Med Genet 38 : 273-278. 2001
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| 21 | GRB10, SRS7, COPG2, UPD7M
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| A narrow segment of maternal uniparental disomy of chromosome 7q31-qter in Silver-Russell syndrome delimits a candidate gene region.
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| Hannula K, Lipsanen-Nyman M, Kontiokari T, Kere J.
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| Am J Hum Genet 68(1):247-53. 2001
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| 22 | GRB10
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| Maternal repression of the human GRB10 gene in the developing central nervous system; evaluation of the role for GRB10 in Silver-Russell syndrome.
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| Hitchins MP, Monk D, Bell GM, Ali Z, Preece MA, Stanier P, Moore GE.
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| Eur J Hum Genet 9(2):82-90. 2001
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| 23 | GRB10, MEST, NOS3, SERPINE1, UPD7M
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| Maternal and paternal chromosomes 7 show differential methylation of many genes in lymphoblast DNA.
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| Hannula K, Lipsanen-Nyman M, Scherer SW, Holmberg C, Hoglund P, Kere J.
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| Genomics 73(1):1-9. 2001
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| 24 | GRB10, GRB14, GRB7
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| The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions.
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| Han DC, Shen TL, Guan JL.
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| Oncogene 20(44):6315-21. Review. 2001
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| 25 | DUP7PP, GRB10, SRS7, UPD7M
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| Duplication of 7p11.2-p13, including GRB10, in Silver-Russell syndrome.
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| Monk D, Wakeling EL, Proud V, Hitchins M, Abu-Amero SN, Stanier P, Preece MA, Moore GE.
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| Am J Hum Genet 66(1):36-46. 2000
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| 26 | GRB10
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| Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion.
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| Blagitko N, Mergenthaler S, Schulz U, Wollmann HA, Craigen W, Eggermann T, Ropers HH, Kalscheuer VM.
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| Hum Mol Genet 9(11):1587-95. 2000
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| 27 | GRB10, SRS7, UPD7M
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| Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome.
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| Yoshihashi H, Maeyama K, Kosaki R, Ogata T, Tsukahara M, Goto Y, Hata J, Matsuo N, Smith RJ, Kosaki K.
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| Am J Hum Genet 67(2):476-82. Epub 2000 Jun 12. 2000
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| 28 | DUP7PP, GRB10, SRS7
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| Duplication of 7p12.1-p13, including GRB10 and IGFBP1, in a mother and daughter with features of Silver-Russell syndrome.
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| Joyce CA, Sharp A, Walker JM, Bullman H, Temple IK.
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| Hum Genet 105(3):273-80. 1999
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| 29 | GRB10
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| Genomic structure of the gene for the SH2 and pleckstrin homology domain-containing protein GRB10 and evaluation of its role in Hirschsprung disease.
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| Angrist M, et al.
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| Oncogene 17 : 3065-3070. 1998
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| 30 | GRB10
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| Assignment of growth factor receptor-bound protein 10 (GRB10) to human chromosome 7p11.2-p12.
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| Jerome CA, et al.
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| Genomics 40 : 215-216. 1997
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| 31 | GRB10
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| Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma.
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| Dong LQ, Du H, Porter SG, Kolakowski LF Jr, Lee AV, Mandarino LJ, Fan J, Yee D, Liu F.
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| J Biol Chem 272(46):29104-12. 1997
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| 32 | GRB10
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| Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains.
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| Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE.
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| J Biol Chem 272(5):2659-67. 1997
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| 33 | GRB10
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| Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling.
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| O'Neill TJ, Rose DW, Pillay TS, Hotta K, Olefsky JM, Gustafson TA.
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| J Biol Chem 271(37):22506-13. 1996
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| 34 | GRB10
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| The cloning of Grb10 reveals a new family of SH2 domain proteins.
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| Ooi J, et al.
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| Oncogene 10 : 1621-1630. 1995
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| 35 | GRB10
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| The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10.
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| Pandey A, Duan H, Di Fiore PP, Dixit VM.
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| J Biol Chem 270(37):21461-3. 1995
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| 36 | GRB10
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| Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function.
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| Liu F, Roth RA.
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| Proc Natl Acad Sci U S A 92(22):10287-91. 1995
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