| 1 | GPX2
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| Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer
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| Ren Z, Liang H, Galbo PM Jr, Dharmaratne M, Kulkarni AS, Fard AT, Aoun ML, Martinez-Lopez N, Suyama K, Benard O, Zheng W, Liu Y, Albanese J, Zheng D, Mar JC, Singh R, Prystowsky MB, Norton L, Hazan RB
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| Proc Natl Acad Sci U S A. Feb 22;119(8):e2107266119. doi: 10.1073/pnas.2107266119. 2022
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| 2 | GPX2
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| GPX2 silencing relieves epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer by downregulating Wnt pathway
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| Li F, Dai L, Niu J.
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| J Cell Physiol. Nov;235(11):7780-7790. doi: 10.1002/jcp.29391. Epub 2019 Nov 27 2020
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| 3 | GPX1, GPX2, GPX3, GPX4
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| Regulatory Phenomena in the Glutathione Peroxidase Superfamily.
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| Brigelius-Flohé R, Flohé L.
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| Antioxid Redox Signal Sep 1;33(7):498-516. doi: 10.1089/ars.2019.7905. Epub 2019 Dec 31 2020
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| 4 | GPX1, GPX2
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| Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms. 2020 PMID:
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| Koeberle SC, Gollowitzer A, Laoukili J, Kranenburg O, Werz O, Koeberle A, Kipp AP.
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| Redox Biol. Jan;28:101388. doi: 10.1016/j.redox.2019.101388. Epub 2019 Nov 16. 2020
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| 5 | GPX2
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| GPX2 promotes development of bladder cancer with squamous cell differentiation through the control of apoptosis
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| Naiki T, Naiki-Ito A, Iida K, Etani T, Kato H, Suzuki S, Yamashita Y, Kawai N, Yasui T, Takahashi S.
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| Oncotarget. Mar 23;9(22):15847-15859. doi: 10.18632/oncotarget.24627 2018
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| 6 | GPX2
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| GPX2 overexpression indicates poor prognosis in patients with hepatocellular carcinoma
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| Liu T, Kan XF, Ma C, Chen LL, Cheng TT, Zou ZW, Li Y, Cao FJ, Zhang WJ, Yao J, Li PD.
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| Tumour Biol. Jun;39(6):1010428317700410. doi: 10.1177/1010428317700410. 2017
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| 7 | GPX2
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| Loss of epithelium-specific GPx2 results in aberrant cell fate decisions during intestinal differentiation
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| Lennicke C, Rahn J, Wickenhauser C, Lichtenfels R, Müller AS, Wessjohann LA, Kipp AP, Seliger B.
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| Oncotarget Nov 23;9(1):539-552. doi: 10.18632/oncotarget.22640. 2017
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| 8 | GPX2
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| GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer
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| Emmink BL, Laoukili J, Kipp AP, Koster J, Govaert KM, Fatrai S, Verheem A, Steller EJ, Brigelius-Flohé R, Jimenez CR, Borel Rinkes IH, Kranenburg O.
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| Cancer Res. Nov 15;74(22):6717-30. doi: 10.1158/0008-5472.CAN-14-1645. Epub 2014 Sep 26. 2014
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| 9 | GPX2, TXNRD2, TXNRD3
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| . The selenoproteins GPx2, TrxR2 and TrxR3 are regulated by Wnt signalling in the intestinal epithelium
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| Kipp AP, Müller MF, Göken EM, Deubel S, Brigelius-Flohé R
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| Biochim Biophys Acta. Oct;1820(10):1588-96. doi: 10.1016/j.bbagen.2012.05.016. Epub 2012 Jun 7. 2012
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| 10 | GPX2
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| Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.
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| Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T.
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| Cancer Res 67(23):11353-8. 2007
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| 11 | GPX2, TP63
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| GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner.
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| Yan W, Chen X.
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| J Biol Chem 281(12):7856-62. Epub 2006 Jan 30. 2006
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| 12 | GPX2
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| Structural organization of the human gastrointestinal glutathione peroxidase (GPX2) promoter and 3'-nontranscribed region: transcriptional response to exogenous redox agents.
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| Kelner MJ, Bagnell RD, Montoya MA, Lanham KA.
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| Gene 248(1-2):109-16. 2000
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| 13 | GPX2
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| Polymorphism and chromosomal localization of the GI-Form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization.
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| Chu FF, et al.
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| Genomics 32 : 272-276. 1996
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| 14 | GPX2, GPX3, GPX4
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| The human glutathione peroxidase genes GPX2, GPX3, and GPX4 map to chromosomes 14, 5, and 19, respectively.
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| Chu FF.
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| Cytogenet Cell Genet 66 : 96-98. 1994
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