| 1 | GPX1, GPX2, GPX3, GPX4
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| Regulatory Phenomena in the Glutathione Peroxidase Superfamily.
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| Brigelius-Flohé R, Flohé L.
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| Antioxid Redox Signal Sep 1;33(7):498-516. doi: 10.1089/ars.2019.7905. Epub 2019 Dec 31 2020
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| 2 | GPX1, GPX2
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| Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms. 2020 PMID:
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| Koeberle SC, Gollowitzer A, Laoukili J, Kranenburg O, Werz O, Koeberle A, Kipp AP.
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| Redox Biol. Jan;28:101388. doi: 10.1016/j.redox.2019.101388. Epub 2019 Nov 16. 2020
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| 3 | GPX1, TFAP2C
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| Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.
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| Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T, Price DH, Domann FE, Weigel RJ.
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| Oncogene 32(34):4043-51. doi: 10.1038/onc.2012.400. Epub 2012 Sep 10.
2013
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| 4 | GPX1
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| Glutathione peroxidase-1 primes pro-inflammatory cytokine production after LPS challenge in vivo.
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| Bozinovski S, Seow HJ, Crack PJ, Anderson GP, Vlahos R.
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| PLoS One 7(3):e33172. Epub 2012 Mar 6.
2012
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| 5 | GPX1
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| Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:Quinone Oxidoreductase 1(NQO1) variants and their association of CAD in patients with type-2 diabetes.
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| Ramprasath T, Murugan PS, Kalaiarasan E, Gomathi P, Rathinavel A, Selvam GS.
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| Mol Cell Biochem 361(1-2):143-50. Epub 2011 Oct 12.
2012
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| 6 | GPX1, GPX3, GPX4, GPX5
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| Glutathione peroxidases at work on epididymal spermatozoa: an example of the dual effect of reactive oxygen species on mammalian male fertilizing ability.
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| Noblanc A, Kocer A, Chabory E, Vernet P, Saez F, Cadet R, Conrad M, Drevet JR.
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| J Androl 32(6):641-50. Epub 2011 Mar 25. Review.
2011
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| 7 | GPX1
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| Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation.
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| Lubos E, Kelly NJ, Oldebeken SR, Leopold JA, Zhang YY, Loscalzo J, Handy DE.
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| J Biol Chem 286(41):35407-17. Epub 2011 Aug 18.
2011
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| 8 | GPX1
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| Divergent roles of glutathione peroxidase-1 (Gpx1) in regulation of leukocyte-endothelial cell interactions in the inflamed cerebral microvasculature.
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| Wong CH, Abeynaike LD, Crack PJ, Hickey MJ.
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| Microcirculation 18(1):12-23. doi: 10.1111/j.1549-8719.2010.00063.x.
2011
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| 9 | GPX1, SELENBP1
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| Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein.
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| Fang W, Goldberg ML, Pohl NM, Bi X, Tong C, Xiong B, Koh TJ, Diamond AM, Yang W.
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| Carcinogenesis 31(8):1360-6. Epub 2010 Jun 7.
2010
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| 10 | GPX1
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| Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression.
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| Lubos E, Mahoney CE, Leopold JA, Zhang YY, Loscalzo J, Handy DE.
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| FASEB J 24(7):2525-32. Epub 2010 Mar 10.
2010
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| 11 | GPX1
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| Lack of glutathione peroxidase 1 accelerates cardiac-specific hypertrophy and dysfunction in angiotensin II hypertension.
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| Ardanaz N, Yang XP, Cifuentes ME, Haurani MJ, Jackson KW, Liao TD, Carretero OA, Pagano PJ.
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| Hypertension 55(1):116-23. Epub 2009 Nov 16.
2010
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| 12 | GPX1, GPX3, GPX4
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| Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy.
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| Mistry HD, Kurlak LO, Williams PJ, Ramsay MM, Symonds ME, Broughton Pipkin F.
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| Placenta 31(5):401-8. doi: 10.1016/j.placenta.2010.02.011. Epub 2010 Mar 19.
2010
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| 13 | GPX1
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| Molecular consequences of genetic variations in the glutathione peroxidase 1 selenoenzyme.
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| Zhuo P, Goldberg M, Herman L, Lee BS, Wang H, Brown RL, Foster CB, Peters U, Diamond AM.
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| Cancer Res 69(20):8183-90. Epub 2009 Oct 13.
2009
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| 14 | GPX1
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| Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells.
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| He T, Joyner MJ, Katusic ZS.
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| Microvasc Res 78(3):447-52. Epub 2009 Sep 4.
2009
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| 15 | GPX1
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| Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans.
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| Jablonska E, Gromadzinska J, Reszka E, Wasowicz W, Sobala W, Szeszenia-Dabrowska N, Boffetta P.
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| Eur J Nutr 48(6):383-6. Epub 2009 May 5.
2009
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| 16 | GPX1
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| Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy.
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| Lei C, Niu X, Wei J, Zhu J, Zhu Y.
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| Clin Chim Acta 399(1-2):102-8. Epub 2008 Oct 2.
2009
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| 17 | GPX1, THBS1
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| Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients.
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| Kato K, Oguri M, Kato N, Hibino T, Yajima K, Yoshida T, Metoki N, Yoshida H, Satoh K, Watanabe S, Yokoi K, Murohara T, Yamada Y.
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| Am J Hypertens 21(9):1023-7. Epub 2008 Jul 3.
2008
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| 18 | GPX1
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| Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.
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| Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ.
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| Arterioscler Thromb Vasc Biol 27(4):850-7. Epub 2007 Jan 25.
2007
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| 19 | GPX1
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| Glutathione peroxidase-1 inhibits UVA-induced AP-2alpha expression in human keratinocytes.
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| Yu L, Venkataraman S, Coleman MC, Spitz DR, Wertz PW, Domann FE.
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| Biochem Biophys Res Commun 351(4):1066-71. Epub 2006 Nov 7. 2006
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| 20 | GPX1
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| Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells.
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| Faucher K, Rabinovitch-Chable H, Cook-Moreau J, Barriere G, Sturtz F, Rigaud M.
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| Mol Cell Biochem 277(1-2):81-7. 2005
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| 21 | GPX1
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| Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer.
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| Hu Y, Benya RV, Carroll RE, Diamond AM.
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| J Nutr 135(12 Suppl):3021S-3024S. Review. 2005
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| 22 | GPX1
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| Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease.
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| Winter JP, Gong Y, Grant PJ, Wild CP.
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| Coron Artery Dis 14(2):149-53. 2003
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| 23 | GPX1
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| Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases.
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| Cao C, Leng Y, Huang W, Liu X, Kufe D.
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| J Biol Chem 278(41):39609-14. Epub 2003 Jul 31.
2003
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| 24 | GPX1, OGG1
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| The effect of hOGG1 and glutathione peroxidase I genotypes and 3p chromosomal loss on 8-hydroxydeoxyguanosine levels in lung cancer.
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| Hardie LJ, Briggs JA, Davidson LA, Allan JM, King RF, Williams GI, Wild CP.
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| Carcinogenesis 21(2):167-72. 2000
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| 25 | RHOA, GPX1
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| Assignment of the ARHA and GPX1 genes to human chromosome bands 3p21.3 by in situ hybridization and with somatic cell hybrids.
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| Kiss C, Li J, Szeles A, Gizatullin RZ, Kashuba VI, Lushnikova T, Protopopov AI, Kelve M, Kiss H, Kholodnyuk ID, Imreh S, Klein G, Zabarovsky ER.
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| Cytogenet Cell Genet 79 : 228-230. 1997
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| 26 | GPX1
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| An in-frame trinucleotide repeat in the coding region of the human cellular glutathione peroxidase (GPX1) gene : in vivo polymorphism and in vitro instability.
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| Shen Q, et al.
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| Genomics 23 : 292-294. 1994
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| 27 | GPX1
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| Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1).
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| Moscow JA, Morrow CS, He R, Mullenbach GT, Cowan KH.
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| J Biol Chem 267(9):5949-58.
1992
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| 28 | GPX1
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| Isolation and chromosomal localization of the human glutathione peroxidase gene.
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| Chada S, et al.
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| Genomics 6 : 268-271. 1990
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| 29 | GPX1
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| Chromosomal sublocalization of the human glutathione peroxidase gene.
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| Le Beau MM, et al.
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| (HGM10) Cytogenet Cell Genet 51 : 1030. 1989
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| 30 | GPX1, GPXP1, GPXP2
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| Glutathione peroxidase gene maps on human chromosomes 3, 21 and X.
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| McBride OW, et al.
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| FASEB J 2 : A1001. 1988
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| 31 | GPX1
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| cDNA sequence coding for human glutathione peroxidase.
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| Sukenaga Y, Ishida K, Takeda T, Takagi K.
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| Nucleic Acids Res 15 : 7178. 1987
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| 32 | ACY1, GPX1
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| Regional assignment of GPX1 and ACY1 on human chromosome 3.
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| Wang HS, et al.
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| Cytogenet Cell Genet 32 : 325. 1982
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| 33 | GPX1
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| Regional mapping of human chromosome 3. Assignment of a glutathione peroxidase-1 gene to 3p13-3q12.
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| Johannsmann R, et al.
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| Hum Genet 56 : 361-363. 1981
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| 34 | GPX1
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| Confirmation of the assignment of a glutathione peroxidase locus to chromosome 3 in man.
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| Donald LJ, et al.
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| Cytogenet Cell Genet 23 : 141-143. 1979
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| 35 | GPX1
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| Regional localization of GPX1 on human chromosome 3.
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| Fidzianska E, et al.
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| Cytogenet Cell Genet 25 : 153. 1979
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| 36 | GPX1
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| Regional assignment of a gene for glutathione peroxidase on human chromosome 3.
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| Johannsmann R, et al.
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| Cytogenet Cell Genet 25 : 167. 1979
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| 37 | GPX1
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| Assignment of a gene for glutathione peroxidase (GPX1) to human chromosome 3.
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| Wijnen LMM, et al.
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| Cytogenet Cell Genet 22 : 232-235. 1978
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| 38 | GPX1
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| AnŽmie hŽmolytique avec dŽficit en glutathion-peroxydase chez un adulte.
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| Boivin P, et al.
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| Enzymol Biol Clin 10 : 68-80. 1969
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| 39 | GPX1
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| Erythrocyte glutathione-peroxidase deficiency and hemolytic disease of the newborn infant.
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| Necheles TF, et al.
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| J Pediatr 72 : 319-324. 1968
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