1 | CDH5, GPSM2
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| VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN.
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| Conway DE, Coon BG, Budatha M, Arsenovic PT, Orsenigo F, Wessel F, Zhang J, Zhuang Z, Dejana E, Vestweber D, Schwartz MA.
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| Curr Biol 27(14):2219-2225.e5. doi: 10.1016/j.cub.2017.06.020. Epub 2017 Jul 14. Erratum in: Curr Biol. 2017 Sep 11;27(17):2727.
2017
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2 | EPB41, GPSM2, NUMA1
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| NuMA localization, stability, and function in spindle orientation involve 4.1 and Cdk1 interactions.
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| Seldin L, Poulson ND, Foote HP, Lechler T.
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| Mol Biol Cell 24(23):3651-62. doi: 10.1091/mbc.E13-05-0277. Epub 2013 Oct 9.
2013
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3 | CMCS, GPSM2
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| GPSM2 Mutations Cause the Brain Malformations and Hearing Loss in Chudley-McCullough Syndrome.
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| Doherty D, Chudley AE, Coghlan G, Ishak GE, Innes AM, Lemire EG, Rogers RC, Mhanni AA, Phelps IG, Jones SJ, Zhan SH, Fejes AP, Shahin H, Kanaan M, Akay H, Tekin M; FORGE Canada Consortium, Triggs-Raine B, Zelinski T.
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| Am J Hum Genet 90(6):1088-93. Epub 2012 May 10.
2012
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4 | DFNB82, GPSM2
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| A truncating mutation in GPSM2 is associated with recessive non-syndromic hearing loss.
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| Yariz KO, Walsh T, Akay H, Duman D, Akkaynak AC, King MC, Tekin M.
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| Clin Genet 81(3):289-93. doi: 10.1111/j.1399-0004.2011.01654.x. Epub 2011 Mar 15.
2012
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5 | DCTN1, GPSM2, NUMA1
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| Asymmetric cell divisions promote Notch-dependent epidermal differentiation.
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| Williams SE, Beronja S, Pasolli HA, Fuchs E.
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| Nature 470(7334):353-8.
2011
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6 | GPSM2, NUMA1
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| A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells.
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| Peyre E, Jaouen F, Saadaoui M, Haren L, Merdes A, Durbec P, Morin X.
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| J Cell Biol 193(1):141-54. Epub 2011 Mar 28.
2011
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7 | DLG1, GPSM2
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| Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules.
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| Zhu J, Shang Y, Xia C, Wang W, Wen W, Zhang M.
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| EMBO J 30(24):4986-97. doi: 10.1038/emboj.2011.428.
2011
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8 | DFNB82, GPSM2
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| Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.
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| Walsh T, Shahin H, Elkan-Miller T, Lee MK, Thornton AM, Roeb W, Abu Rayyan A, Loulus S, Avraham KB, King MC, Kanaan M.
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| Am J Hum Genet 87(1):90-4. Epub 2010 Jun 17.PMID: 20602914 2010
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9 | GPSM2, PBK
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| Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
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| Fukukawa C, Ueda K, Nishidate T, Katagiri T, Nakamura Y.
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| Genes Chromosomes Cancer 49(10):861-72.PMID: 20589935 2010
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10 | GPSM2
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| Pins homolog LGN regulates meiotic spindle organization in mouse oocytes.
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| Guo X, Gao S.
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| Cell Res 19(7):838-48.
2009
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11 | GPSM2
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| Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.
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| Konno D, Shioi G, Shitamukai A, Mori A, Kiyonari H, Miyata T, Matsuzaki F.
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| Nat Cell Biol 10(1):93-101. Epub 2007 Dec 16. 2008
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12 | INSC, GPSM2, PARD3B, PROX2, GPSM1
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| Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.
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| Izaki T, Kamakura S, Kohjima M, Sumimoto H.
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| Biochem Biophys Res Commun 341(4):1001-6. Epub 2006 Jan 24. 2006
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13 | GPSM2
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| Playing ping pong with pins: cortical and microtubule-induced polarity.
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| Ahringer J.
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| Cell 123(7):1184-6. 2005
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14 | GPSM2, NUMA1
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| Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins.
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| Du Q, Macara IG.
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| Cell 119(4):503-16. 2004
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15 | GPSM2
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| Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression.
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| Kaushik R, Yu F, Chia W, Yang X, Bahri S.
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| Mol Biol Cell 14(8):3144-55. Epub 2003 May 3. 2003
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16 | GPSM2
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| Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.
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| Blumer JB, Chandler LJ, Lanier SM.
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| J Biol Chem 277(18):15897-903. Epub 2002 Feb 06. 2002
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17 | GPSM2
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| Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2.
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| Mochizuki N, Cho G, Wen B, Insel PA.
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| Gene 181(1-2):39-43. 1996
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