| 1 | ACDC, GPNMB
|
| Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.
|
| Yang CF, Lin SP, Chiang CP, Wu YH, H'ng WS, Chang CP, Chen YT, Wu JY.
|
| Am J Hum Genet 102(2):219-232. doi: 10.1016/j.ajhg.2017.12.012. Epub 2018 Jan 11.
2018
|
| 2 | GPNMB
|
| Overexpression of GPNMB predicts an unfavorable outcome of epithelial ovarian cancer.
|
| Ma RQ, Tang ZJ, Ye X, Cheng HY, Sun KK, Chang XH, Cui H.
|
| Arch Gynecol Obstet rch Gynecol Obstet. 2018 Feb 10. doi: 10.1007/s00404-018-4699-3. [Epub ahead of print]
2018
|
| 3 | GPNMB
|
| Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB) and Cancer: A Novel Potential Therapeutic Target.
|
| Taya M, Hammes SR.
|
| Steroids teroids. 2017 Oct 31. pii: S0039-128X(17)30193-9. doi: 10.1016/j.steroids.2017.10.013. [Epub ahead of print]
2017
|
| 4 | GPNMB
|
| Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.
|
| Budge KM, Neal ML, Richardson JR, Safadi FF.
|
| Mol Neurobiol ol Neurobiol. 2017 Aug 30. doi: 10.1007/s12035-017-0707-z. [Epub ahead of print] Review.
2017
|
| 5 | GPNMB
|
| The laminin-derived peptide C16 regulates GPNMB expression and function in breast cancer.
|
| Smuczek B, Santos ES, Siqueira AS, Pinheiro JJV, Freitas VM, Jaeger RG.
|
| Exp Cell Res 358(2):323-334. doi: 10.1016/j.yexcr.2017.07.005. Epub 2017 Jul 5.
2017
|
| 6 | GPNMB
|
| Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
|
| Järve A, Mühlstedt S, Qadri F, Nickl B, Schulz H, Hübner N, Özcelik C, Bader M.
|
| FASEB J 31(2):556-568. doi: 10.1096/fj.201600613R. Epub 2016 Oct 25.
2017
|
| 7 | GPNMB
|
| GPNMB promotes proliferation of developing eosinophils.
|
| Hwang SM, Kang JH, Kim BK, Uhm TG, Kim HJ, Lee HH, Binas B, Chung IY.
|
| J Biochem 162(2):85-91. doi: 10.1093/jb/mvx002.
2017
|
| 8 | ATP1A1, ATP1A2, ATP1A3, ATP1A4, GPNMB
|
| Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.
|
| Ono Y, Chiba S, Yano H, Nakayama N, Saio M, Tsuruma K, Shimazawa M, Iwama T, Hara H.
|
| Biochem Biophys Res Commun 481(1-2):7-12. doi: 10.1016/j.bbrc.2016.11.034. Epub 2016 Nov 9.
2016
|
| 9 | GPNMB
|
| Glycoprotein non-metastaticmelanoma protein B promotes glioma motility and angiogenesis through the Wnt/β-catenin signaling pathway.
|
| Bao G, Wang N, Li R, Xu G, Liu P, He B.
|
| Exp Biol Med (Maywood) 241(17):1968-1976. Epub 2016 Jun 21.
2016
|
| 10 | GPNMB
|
| Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.
|
| Ono Y, Tsuruma K, Takata M, Shimazawa M, Hara H.
|
| Sci Rep 6:23241. doi: 10.1038/srep23241.
2016
|
| 11 | GPNMB
|
| Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease.
|
| Marques AR, Gabriel TL, Aten J, van Roomen CP, Ottenhoff R, Claessen N, Alfonso P, Irún P, Giraldo P, Aerts JM, van Eijk M.
|
| PLoS One 11(1):e0147208. doi: 10.1371/journal.pone.0147208. eCollection 2016.
2016
|
| 12 | GPNMB
|
| Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration Via a CD44-Dependent Mechanism.
|
| Yu B, Sondag GR, Malcuit C, Kim MH, Safadi FF.
|
| J Cell Biochem 117(7):1511-21. doi: 10.1002/jcb.25394.
2016
|
| 13 | GPNMB, MITF
|
| The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells.
|
| Gutknecht M, Geiger J, Joas S, Dörfel D, Salih HR, Müller MR, Grünebach F, Rittig SM.
|
| Cell Commun Signal 13:19. doi: 10.1186/s12964-015-0099-5. Erratum in: Cell Commun Signal. 2016;14(1):11.
2015
|
| 14 | GPNMB
|
| The extracellular fragment of GPNMB (Glycoprotein nonmelanosoma protein B, osteoactivin) improves memory and increases hippocampal GluA1 levels in mice.
|
| Murata K, Yoshino Y, Tsuruma K, Moriguchi S, Oyagi A, Tanaka H, Ishisaka M, Shimazawa M, Fukunaga K, Hara H.
|
| J Neurochem 132(5):583-94. doi: 10.1111/jnc.13010. Epub 2015 Jan 29.
2015
|
| 15 | GPNMB
|
| Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction.
|
| Gabriel TL, Tol MJ, Ottenhof R, van Roomen C, Aten J, Claessen N, Hooibrink B, de Weijer B, Serlie MJ, Argmann C, van Elsenburg L, Aerts JM, van Eijk M.
|
| Diabetes 63(10):3310-23. doi: 10.2337/db13-1720. Epub 2014 May 1.
2014
|
| 16 | GPNMB
|
| Osteoactivin promotes osteoblast adhesion through HSPG and αvβ1 integrin.
|
| Moussa FM, Hisijara IA, Sondag GR, Scott EM, Frara N, Abdelmagid SM, Safadi FF.
|
| J Cell Biochem 115(7):1243-53. doi: 10.1002/jcb.24760.
2014
|
| 17 | FGFR1, GPNMB
|
| GPNMB enhances bone regeneration by promoting angiogenesis and osteogenesis: potential role for tissue engineering bone.
|
| Hu X, Zhang P, Xu Z, Chen H, Xie X.
|
| J Cell Biochem 114(12):2729-37. doi: 10.1002/jcb.24621.
2013
|
| 18 | GPNMB
|
| The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis.
|
| Tanaka H, Shimazawa M, Kimura M, Takata M, Tsuruma K, Yamada M, Takahashi H, Hozumi I, Niwa J, Iguchi Y, Nikawa T, Sobue G, Inuzuka T, Hara H.
|
| Sci Rep 2:573. doi: 10.1038/srep00573. Epub 2012 Aug 13.
2012
|
| 19 | GPNMB
|
| Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.
|
| Sheng MH, Wergedal JE, Mohan S, Amoui M, Baylink DJ, Lau KH.
|
| PLoS One 7(4):e35280. doi: 10.1371/journal.pone.0035280. Epub 2012 Apr 20.
2012
|
| 20 | DLX3, DLX5, GPNMB, MSX2
|
| Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts.
|
| Singh M, Del Carpio-Cano FE, Monroy MA, Popoff SN, Safadi FF.
|
| J Cell Physiol 227(1):390-9. doi: 10.1002/jcp.22791.
2012
|
| 21 | ADAM10, GPNMB
|
| ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.
|
| Rose AA, Annis MG, Dong Z, Pepin F, Hallett M, Park M, Siegel PM.
|
| PLoS One 5(8):e12093. doi: 10.1371/journal.pone.0012093.
2010
|
| 22 | GPNMB, SDC4
|
| The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses.
|
| Chung JS, Bonkobara M, Tomihari M, Cruz PD Jr, Ariizumi K.
|
| Eur J Immunol 39(4):965-74.
2009
|
| 23 | GPNMB
|
| Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.
|
| Ripoll VM, Meadows NA, Raggatt LJ, Chang MK, Pettit AR, Cassady AI, Hume DA.
|
| Gene 413(1-2):32-41. Epub 2008 Jan 26. 2008
|
| 24 | GPNMB, ITGB1, ITGB3
|
| Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
|
| Sheng MH, Wergedal JE, Mohan S, Lau KH.
|
| FEBS Lett 582(10):1451-8. Epub 2008 Mar 31. 2008
|
| 25 | GPNMB
|
| Role of human HGFIN/nmb in breast cancer.
|
| Metz RL, Patel PS, Hameed M, Bryan M, Rameshwar P.
|
| Breast Cancer Res 9(5):R58. 2007
|
| 26 | GPNMB
|
| Osteoactivin promotes breast cancer metastasis to bone.
|
| Rose AA, Pepin F, Russo C, Abou Khalil JE, Hallett M, Siegel PM.
|
| Mol Cancer Res 5(10):1001-14. 2007
|
| 27 | GPNMB
|
| Cloning and characterization of the 5' flanking region of the HGFIN gene indicate a cooperative role among p53 and cytokine-mediated transcription factors: relevance to cell cycle regulation.
|
| Metz RL, Yehia G, Fernandes H, Donnelly RJ, Rameshwar P.
|
| Cell Cycle 4(2):315-22. Epub 2005 Feb 13. 2005
|
| 28 | GPNMB
|
| Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice.
|
| Anderson MG, Smith RS, Hawes NL, Zabaleta A, Chang B, Wiggs JL, John SW.
|
| Nat Genet 30(1):81-5. 2002
|
| 29 | GPNMB, CYMD
|
| mRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris.
|
| Bchner D, Schrder D, Gross G.
|
| Brain Res Gene Expr Patterns 1(3-4):159-65. 2002
|