Citations for
1ACDC, GPNMB
Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans.
Yang CF, Lin SP, Chiang CP, Wu YH, H'ng WS, Chang CP, Chen YT, Wu JY.
Am J Hum Genet 102(2):219-232. doi: 10.1016/j.ajhg.2017.12.012. Epub 2018 Jan 11. 2018
2GPNMB
Overexpression of GPNMB predicts an unfavorable outcome of epithelial ovarian cancer.
Ma RQ, Tang ZJ, Ye X, Cheng HY, Sun KK, Chang XH, Cui H.
Arch Gynecol Obstet rch Gynecol Obstet. 2018 Feb 10. doi: 10.1007/s00404-018-4699-3. [Epub ahead of print] 2018
3GPNMB
Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB) and Cancer: A Novel Potential Therapeutic Target.
Taya M, Hammes SR.
Steroids teroids. 2017 Oct 31. pii: S0039-128X(17)30193-9. doi: 10.1016/j.steroids.2017.10.013. [Epub ahead of print] 2017
4GPNMB
Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.
Budge KM, Neal ML, Richardson JR, Safadi FF.
Mol Neurobiol ol Neurobiol. 2017 Aug 30. doi: 10.1007/s12035-017-0707-z. [Epub ahead of print] Review. 2017
5GPNMB
The laminin-derived peptide C16 regulates GPNMB expression and function in breast cancer.
Smuczek B, Santos ES, Siqueira AS, Pinheiro JJV, Freitas VM, Jaeger RG.
Exp Cell Res 358(2):323-334. doi: 10.1016/j.yexcr.2017.07.005. Epub 2017 Jul 5. 2017
6GPNMB
Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction.
Järve A, Mühlstedt S, Qadri F, Nickl B, Schulz H, Hübner N, Özcelik C, Bader M.
FASEB J 31(2):556-568. doi: 10.1096/fj.201600613R. Epub 2016 Oct 25. 2017
7GPNMB
GPNMB promotes proliferation of developing eosinophils.
Hwang SM, Kang JH, Kim BK, Uhm TG, Kim HJ, Lee HH, Binas B, Chung IY.
J Biochem 162(2):85-91. doi: 10.1093/jb/mvx002. 2017
8ATP1A1, ATP1A2, ATP1A3, ATP1A4, GPNMB
Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.
Ono Y, Chiba S, Yano H, Nakayama N, Saio M, Tsuruma K, Shimazawa M, Iwama T, Hara H.
Biochem Biophys Res Commun 481(1-2):7-12. doi: 10.1016/j.bbrc.2016.11.034. Epub 2016 Nov 9. 2016
9GPNMB
Glycoprotein non-metastaticmelanoma protein B promotes glioma motility and angiogenesis through the Wnt/β-catenin signaling pathway.
Bao G, Wang N, Li R, Xu G, Liu P, He B.
Exp Biol Med (Maywood) 241(17):1968-1976. Epub 2016 Jun 21. 2016
10GPNMB
Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.
Ono Y, Tsuruma K, Takata M, Shimazawa M, Hara H.
Sci Rep 6:23241. doi: 10.1038/srep23241. 2016
11GPNMB
Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease.
Marques AR, Gabriel TL, Aten J, van Roomen CP, Ottenhoff R, Claessen N, Alfonso P, Irún P, Giraldo P, Aerts JM, van Eijk M.
PLoS One 11(1):e0147208. doi: 10.1371/journal.pone.0147208. eCollection 2016. 2016
12GPNMB
Macrophage-Associated Osteoactivin/GPNMB Mediates Mesenchymal Stem Cell Survival, Proliferation, and Migration Via a CD44-Dependent Mechanism.
Yu B, Sondag GR, Malcuit C, Kim MH, Safadi FF.
J Cell Biochem 117(7):1511-21. doi: 10.1002/jcb.25394. 2016
13GPNMB, MITF
The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells.
Gutknecht M, Geiger J, Joas S, Dörfel D, Salih HR, Müller MR, Grünebach F, Rittig SM.
Cell Commun Signal 13:19. doi: 10.1186/s12964-015-0099-5. Erratum in: Cell Commun Signal. 2016;14(1):11. 2015
14GPNMB
The extracellular fragment of GPNMB (Glycoprotein nonmelanosoma protein B, osteoactivin) improves memory and increases hippocampal GluA1 levels in mice.
Murata K, Yoshino Y, Tsuruma K, Moriguchi S, Oyagi A, Tanaka H, Ishisaka M, Shimazawa M, Fukunaga K, Hara H.
J Neurochem 132(5):583-94. doi: 10.1111/jnc.13010. Epub 2015 Jan 29. 2015
15GPNMB
Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction.
Gabriel TL, Tol MJ, Ottenhof R, van Roomen C, Aten J, Claessen N, Hooibrink B, de Weijer B, Serlie MJ, Argmann C, van Elsenburg L, Aerts JM, van Eijk M.
Diabetes 63(10):3310-23. doi: 10.2337/db13-1720. Epub 2014 May 1. 2014
16GPNMB
Osteoactivin promotes osteoblast adhesion through HSPG and αvβ1 integrin.
Moussa FM, Hisijara IA, Sondag GR, Scott EM, Frara N, Abdelmagid SM, Safadi FF.
J Cell Biochem 115(7):1243-53. doi: 10.1002/jcb.24760. 2014
17FGFR1, GPNMB
GPNMB enhances bone regeneration by promoting angiogenesis and osteogenesis: potential role for tissue engineering bone.
Hu X, Zhang P, Xu Z, Chen H, Xie X.
J Cell Biochem 114(12):2729-37. doi: 10.1002/jcb.24621. 2013
18GPNMB
The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis.
Tanaka H, Shimazawa M, Kimura M, Takata M, Tsuruma K, Yamada M, Takahashi H, Hozumi I, Niwa J, Iguchi Y, Nikawa T, Sobue G, Inuzuka T, Hara H.
Sci Rep 2:573. doi: 10.1038/srep00573. Epub 2012 Aug 13. 2012
19GPNMB
Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.
Sheng MH, Wergedal JE, Mohan S, Amoui M, Baylink DJ, Lau KH.
PLoS One 7(4):e35280. doi: 10.1371/journal.pone.0035280. Epub 2012 Apr 20. 2012
20DLX3, DLX5, GPNMB, MSX2
Homeodomain transcription factors regulate BMP-2-induced osteoactivin transcription in osteoblasts.
Singh M, Del Carpio-Cano FE, Monroy MA, Popoff SN, Safadi FF.
J Cell Physiol 227(1):390-9. doi: 10.1002/jcp.22791. 2012
21ADAM10, GPNMB
ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.
Rose AA, Annis MG, Dong Z, Pepin F, Hallett M, Park M, Siegel PM.
PLoS One 5(8):e12093. doi: 10.1371/journal.pone.0012093. 2010
22GPNMB, SDC4
The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses.
Chung JS, Bonkobara M, Tomihari M, Cruz PD Jr, Ariizumi K.
Eur J Immunol 39(4):965-74. 2009
23GPNMB
Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.
Ripoll VM, Meadows NA, Raggatt LJ, Chang MK, Pettit AR, Cassady AI, Hume DA.
Gene 413(1-2):32-41. Epub 2008 Jan 26. 2008
24GPNMB, ITGB1, ITGB3
Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.
Sheng MH, Wergedal JE, Mohan S, Lau KH.
FEBS Lett 582(10):1451-8. Epub 2008 Mar 31. 2008
25GPNMB
Role of human HGFIN/nmb in breast cancer.
Metz RL, Patel PS, Hameed M, Bryan M, Rameshwar P.
Breast Cancer Res 9(5):R58. 2007
26GPNMB
Osteoactivin promotes breast cancer metastasis to bone.
Rose AA, Pepin F, Russo C, Abou Khalil JE, Hallett M, Siegel PM.
Mol Cancer Res 5(10):1001-14. 2007
27GPNMB
Cloning and characterization of the 5' flanking region of the HGFIN gene indicate a cooperative role among p53 and cytokine-mediated transcription factors: relevance to cell cycle regulation.
Metz RL, Yehia G, Fernandes H, Donnelly RJ, Rameshwar P.
Cell Cycle 4(2):315-22. Epub 2005 Feb 13. 2005
28GPNMB
Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice.
Anderson MG, Smith RS, Hawes NL, Zabaleta A, Chang B, Wiggs JL, John SW.
Nat Genet 30(1):81-5. 2002
29GPNMB, CYMD
mRNA expression of the murine glycoprotein (transmembrane) nmb (Gpnmb) gene is linked to the developing retinal pigment epithelium and iris.
BŠchner D, Schršder D, Gross G.
Brain Res Gene Expr Patterns 1(3-4):159-65. 2002