Citations for
1GPER1, MDH2
MDH2 Stimulated by Estrogen-GPR30 Pathway Down-Regulated PTEN Expression Promoting the Proliferation and Invasion of Cells in Endometrial Cancer.
Zhuang Y, Xiang J, Bao W, Sun Y, Wang L, Tan M, He Y, Xi X.
Transl Oncol 10(2):203-210. doi: 10.1016/j.tranon.2017.01.009. [Epub ahead of print] 2017
2GPER1, SLC9A3R1
NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer.
Meng R, Qin Q, Xiong Y, Wang Y, Zheng J, Zhao Y, Tao T, Wang Q, Liu H, Wang S, Jiang WG, He J.
Oncotarget 7(34):54983-54997. doi: 10.18632/oncotarget.10713. 2016
3GPER1
Cardioprotective role of G-Protein Coupled Estrogen Receptor 1 (GPER1).
Koganti S.
Mol Membr Biol ol Membr Biol. 2015 Apr 29:1-4. [Epub ahead of print] 2015
4GPER1
Decreased Expression of GPER1 Gene and Protein in Goiter.
Weber R, Bertoni AP, Bessestil LW, Brum IS, Furlanetto TW.
Int J Endocrinol 2015:869431. doi: 10.1155/2015/869431. Epub 2015 Mar 12. 2015
5GPER1
GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus.
Kwon O, Kang ES, Kim I, Shin S, Kim M, Kwon S, Oh SR, Ahn YS, Kim CH.
Metabolism 63(11):1455-61. doi: 10.1016/j.metabol.2014.07.015. Epub 2014 Aug 9. 2014
6GPER1
GPER1 is regulated by insulin in cancer cells and cancer-associated fibroblasts.
De Marco P, Romeo E, Vivacqua A, Malaguarnera R, Abonante S, Romeo F, Pezzi V, Belfiore A, Maggiolini M.
Endocr Relat Cancer 21(5):739-53. doi: 10.1530/ERC-14-0245. Epub 2014 Jul 10. 2014
7AKAP5, DLG1, DLG4, GPER1
G protein-coupled receptor 30 (GPR30) forms a plasma membrane complex with membrane-associated guanylate kinases (MAGUKs) and protein kinase A-anchoring protein 5 (AKAP5) that constitutively inhibits cAMP production.
Broselid S, Berg KA, Chavera TA, Kahn R, Clarke WP, Olde B, Leeb-Lundberg LM.
J Biol Chem 289(32):22117-27. doi: 10.1074/jbc.M114.566893. Epub 2014 Jun 24. 2014
8GPER1
Role of G protein-coupled estrogen receptor 1 in modulating transforming growth factor-β stimulated mesangial cell extracellular matrix synthesis and migration.
Li YC, Ding XS, Li HM, Zhang Y, Bao J.
Mol Cell Endocrinol 391(1-2):50-9. doi: 10.1016/j.mce.2014.04.014. Epub 2014 May 1. 2014
9GPER1
Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis.
Vaucher L, Funaro MG, Mehta A, Mielnik A, Bolyakov A, Prossnitz ER, Schlegel PN, Paduch DA.
PLoS One 9(4):e92425. doi: 10.1371/journal.pone.0092425. eCollection 2014. 2014
10GPER1
GPR30 mediates estrogen rapid signaling and neuroprotection.
Tang H, Zhang Q, Yang L, Dong Y, Khan M, Yang F, Brann DW, Wang R.
Mol Cell Endocrinol 387(1-2):52-8. doi: 10.1016/j.mce.2014.01.024. Epub 2014 Mar 1. 2014
11GPER1
GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts.
Luo H, Yang G, Yu T, Luo S, Wu C, Sun Y, Liu M, Tu G.
Endocr Relat Cancer 21(2):355-69. doi: 10.1530/ERC-13-0237. Print 2014 Apr. 2014
12AKAP5, GPER1
G protein-coupled receptor 30 (GPR30) forms a plasma membrane complex with membrane-associated guanylate kinases (MAGUKs) and protein kinase A-anchoring protein 5 (AKAP5) that constitutively inhibits cAMP production.
Broselid S, Berg KA, Chavera TA, Kahn R, Clarke WP, Olde B, Leeb-Lundberg LM.
J Biol Chem 289(32):22117-27. doi: 10.1074/jbc.M114.566893. Epub 2014 Jun 24. 2014
13GPER1, IGF1
Insulin-like growth factor-I regulates GPER expression and function in cancer cells.
De Marco P, Bartella V, Vivacqua A, Lappano R, Santolla MF, Morcavallo A, Pezzi V, Belfiore A, Maggiolini M.
Oncogene 32(6):678-88. doi: 10.1038/onc.2012.97. Epub 2012 Mar 19. 2013
14GPER1
GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state.
Sharma G, Hu C, Brigman JL, Zhu G, Hathaway HJ, Prossnitz ER.
Endocrinology 154(11):4136-45. doi: 10.1210/en.2013-1357. Epub 2013 Aug 22. 2013
15GPER1, RAMP3
G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection.
Lenhart PM, Broselid S, Barrick CJ, Leeb-Lundberg LM, Caron KM.
J Mol Endocrinol 51(1):191-202. doi: 10.1530/JME-13-0021. Print 2013. 2013
16GPER1
GPER: a novel target for non-genomic estrogen action in the cardiovascular system.
Han G, Li F, Yu X, White RE.
Pharmacol Res 71:53-60. doi: 10.1016/j.phrs.2013.02.008. Epub 2013 Mar 4. Review. 2013
17EDN1, GPER1
GPER regulates endothelin-dependent vascular tone and intracellular calcium.
Meyer MR, Field AS, Kanagy NL, Barton M, Prossnitz ER.
Life Sci 91(13-14):623-7. doi: 10.1016/j.lfs.2012.01.007. Epub 2012 Feb 2. 2012
18GPER1
G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation.
Chakrabarti S, Davidge ST.
PLoS One 7(12):e52357. doi: 10.1371/journal.pone.0052357. Epub 2012 Dec 20. 2012
19BSG, GPER1
Stimulation of GPR30 increases release of EMMPRIN-containing microvesicles in human uterine epithelial cells.
Burnett LA, Light MM, Mehrotra P, Nowak RA.
J Clin Endocrinol Metab 97(12):4613-22. doi: 10.1210/jc.2012-2098. Epub 2012 Sep 25. Erratum in: J Clin Endocrinol Metab. 2013 Nov;98(11):4546. 2012
20GPER1
G protein-coupled estrogen receptor (GPER) expression in normal and abnormal endometrium.
Plante BJ, Lessey BA, Taylor RN, Wang W, Bagchi MK, Yuan L, Scotchie J, Fritz MA, Young SL.
Reprod Sci 19(7):684-93. doi: 10.1177/1933719111431000. Epub 2012 Feb 28. 2012
21GPER1
GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone.
Gros R, Ding Q, Sklar LA, Prossnitz EE, Arterburn JB, Chorazyczewski J, Feldman RD.
Hypertension 57(3):442-51. doi: 10.1161/HYPERTENSIONAHA.110.161653. Epub 2011 Jan 17. 2011
22GPER1
GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus.
Hammond R, Nelson D, Gibbs RB.
Psychoneuroendocrinology 36(2):182-92. doi: 10.1016/j.psyneuen.2010.07.007. Epub 2010 Aug 8. 2011
23GPER1
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
Ariazi EA, Brailoiu E, Yerrum S, Shupp HA, Slifker MJ, Cunliffe HE, Black MA, Donato AL, Arterburn JB, Oprea TI, Prossnitz ER, Dun NJ, Jordan VC.
Cancer Res 70(3):1184-94. Epub 2010 Jan 19.PMID: 20086172 2010
24GPER1
G-protein coupled estrogen receptor 1 expression in rat and human heart: Protective role during ischaemic stress.
Patel VH, Chen J, Ramanjaneya M, Karteris E, Zachariades E, Thomas P, Been M, Randeva HS.
Int J Mol Med 26(2):193-199.PMID: 20596598 2010
25GPER1
G protein-coupled estrogen receptor 1 (GPER, GPR 30) in normal human endometrium and early pregnancy decidua.
Kolkova Z, Noskova V, Ehinger A, Hansson S, CasslÚn B.
Mol Hum Reprod ol Hum Reprod. 2010 May 27. [Epub ahead of print]PMID: 20508064 2010
26GPER1
Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells.
Lappano R, Rosano C, De Marco P, De Francesco EM, Pezzi V, Maggiolini M.
Mol Cell Endocrinol 320(1-2):162-70. Epub 2010 Feb 6.PMID: 20138962 2010
27GPER1
In vivo functions of GPR30/GPER-1, a membrane receptor for estrogen: from discovery to functions in vivo.
Mizukami Y.
Endocr J 57(2):101-7. Epub 2009 Dec 8. Review.PMID: 19996532 2010
28GPER1
Estrogen receptors and function in the male reproductive system.
Lazari MF, Lucas TF, Yasuhara F, Gomes GR, Siu ER, Royer C, Fernandes SA, Porto CS.
Arq Bras Endocrinol Metabol 53(8):923-33.PMID: 20126844 2009
29GPER1
G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells.
Vivacqua A, Lappano R, De Marco P, Sisci D, Aquila S, De Amicis F, Fuqua SA, And˛ S, Maggiolini M.
Mol Endocrinol 23(11):1815-26. Epub 2009 Sep 11.PMID: 19749156 2009
30GPER1
Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER.
Prossnitz ER, Barton M.
Prostaglandins Other Lipid Mediat 89(3-4):89-97. Epub 2009 May 13. Review.PMID: 19442754 2009
31GPER1, RGS2, RUNX2
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
Teplyuk NM, Galindo M, Teplyuk VI, Pratap J, Young DW, Lapointe D, Javed A, Stein JL, Lian JB, Stein GS, van Wijnen AJ.
J Biol Chem 283(41):27585-97. Epub 2008 Jul 14. 2008
32GPER1
GPR30 contributes to estrogen-induced thymic atrophy.
Wang C, Dehghani B, Magrisso IJ, Rick EA, Bonhomme E, Cody DB, Elenich LA, Subramanian S, Murphy SJ, Kelly MJ, Rosenbaum JS, Vandenbark AA, Offner H.
Mol Endocrinol 22(3):636-48. Epub 2007 Dec 6.PMID: 18063692 2008
33GPER1
The ins and outs of GPR30: a transmembrane estrogen receptor.
Prossnitz ER, Oprea TI, Sklar LA, Arterburn JB.
J Steroid Biochem Mol Biol 109(3-5):350-3. Epub 2008 Mar 6. Review.PMID: 18406603 2008
34GPER1
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation.
Teng J, Wang ZY, Prossnitz ER, Bjorling DE.
Endocrinology 149(8):4024-34. Epub 2008 May 8. 2008
35GPER1
GPR30 Estrogen Receptor Expression in the Growth Plate Declines as Puberty Progresses.
Chagin AS, SŐvendahl L.
J Clin Endocrinol Metab 92(12):4873-7. Epub 2007 Sep 18. 2007
36GPER1
protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.
Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, And˛ S, Maggiolini M.
Cancer Res 67(4):1859-66. 2007
37GPER1
GPR30: A G protein-coupled receptor for estrogen.
Prossnitz ER, Arterburn JB, Sklar LA.
Mol Cell Endocrinol 265-266:138-42. Epub 2007 Jan 11. Review. 2007
38GPER1
Virtual and biomolecular screening converge on a selective agonist for GPR30.
Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER.
Nat Chem Biol 2(4):207-12. Epub 2006 Mar 5. 2006
39GPER1
Cloning of novel LERGU mRNAs in GPR30 3' untranslated region and detection of 2 bp-deletion polymorphism in gastric cancer.
Kakinuma N, Sato M, Yamada T, Kohu K, Nakajima M, Akiyama T, Ohwada S, Shibanaka Y.
Cancer Sci 96(3):191-6. 2005
40GPER1
A transmembrane intracellular estrogen receptor mediates rapid cell signaling.
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER.
Science 307(5715):1625-30. Epub 2005 Feb 10. 2005
41GPER1
G protein-coupled receptor 30 is critical for a progestin-induced growth inhibition in MCF-7 breast cancer cells.
Ahola TM, Manninen T, Alkio N, Ylikomi T.
Endocrinology 143(9):3376-84. 2002
42GPER1, GPR35
Discovery of three novel G-protein-coupled receptor gene.
O'Dowd BF, Nguyen T, Marchese A, Cheng R, Lynch KR, Heng HH, Kolakowski LF Jr, George SR.
Genomics 47(2):310-3. 1998
43GPER1
Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer.
Carmeci C, Thompson DA, Ring HZ, Francke U, Weigel RJ.
Genomics 45(3):607-17. 1997
44GPER1
Cloning of a novel member of the G protein-coupled receptor family related to peptide receptors.
Feng Y, et al.
Biochem Biophys Res Commun 231 : 651-654. 1997
45GPER1
A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue.
Kvingedal AM, et al.
FEBS Lett 407 : 59-62. 1997
46GPER1
Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress.
Takada Y, et al.
Biochem Biophys Res Commun 240 : 737-741. 1997
47GPER1
Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues.
Owman C, et al.
Biochem Biophys Res Commun 228 : 285-292. 1996