| 1 | GP6
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| Ceramidase critically affects GPVI-dependent platelet activation and thrombus formation.
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| Münzer P, Mittelstädt S, Geue S, Manke MC, Walker-Allgaier B, Lang F, Gawaz M, Borst O.
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| Biochem Biophys Res Commun 496(3):792-798. doi: 10.1016/j.bbrc.2018.01.155. Epub 2018 Feb 1.
2018
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| 2 | GP6
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| Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets.
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| Poulter NS, Pollitt AY, Owen DM, Gardiner EE, Andrews RK, Shimizu H, Ishikawa D, Bihan D, Farndale RW, Moroi M, Watson SP, Jung SM.
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| J Thromb Haemost 15(3):549-564. doi: 10.1111/jth.13613. Epub 2017 Feb 16.
2017
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| 3 | GP6, TSPAN9
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| Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation
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| Haining EJ, Matthews AL, Noy PJ, Romanska HM, Harris HJ, Pike J, Morowski M, Gavin RL, Yang J, Milhiet PE, Berditchevski F, Nieswandt B, Poulter NS, Watson SP, Tomlinson MG.
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| Platelets. Nov;28(7):629-642. doi: 10.1080/09537104.2016.1254175. Epub 2016 Dec 29. 2017
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| 4 | GP6, SYK, UBASH3B
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| TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk.
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| Reppschläger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY.
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| J Biol Chem 291(43):22427-22441. Epub 2016 Sep 8. Erratum in: J Biol Chem. 2017 Mar 10;292(10 ):4360.
2016
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| 5 | GP6, RHOG
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| Platelet Rho GTPases-a focus on novel players, roles and relationships.
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| Goggs R, Williams CM, Mellor H, Poole AW.
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| Biochem J 466(3):431-42. doi: 10.1042/BJ20141404. Review.
2015
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| 6 | GP6
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| Genetic variations of the GP6 regulatory region in patients with sticky platelet syndrome and miscarriage.
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| Sokol J, Skerenova M, Biringer K, Lasabova Z, Stasko J, Kubisz P.
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| Expert Rev Hematol 8(6):863-8. doi: 10.1586/17474086.2015.1083417. Epub 2015 Aug 25. Review.
2015
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| 7 | GP6
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| Fibrin activates GPVI in human and mouse platelets.
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| Alshehri OM, Hughes CE, Montague S, Watson SK, Frampton J, Bender M, Watson SP.
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| Blood 126(13):1601-8. doi: 10.1182/blood-2015-04-641654. Epub 2015 Aug 17.
2015
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| 8 | GP6
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| Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation.
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| Mammadova-Bach E, Ollivier V, Loyau S, Schaff M, Dumont B, Favier R, Freyburger G, Latger-Cannard V, Nieswandt B, Gachet C, Mangin PH, Jandrot-Perrus M.
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| Blood 126(5):683-91. doi: 10.1182/blood-2015-02-629717. Epub 2015 May 14.
2015
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| 9 | GP6
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| Platelet-specific collagen receptor glycoprotein VI gene variants affect recurrent pregnancy loss.
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| Siddesh A, Parveen F, Misra MK, Phadke SR, Agrawal S.
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| Fertil Steril 102(4):1078-1084.e3. doi: 10.1016/j.fertnstert.2014.07.002. Epub 2014 Jul 30.
2014
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| 10 | GP6
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| Elevated plasma levels of soluble platelet glycoprotein VI (GPVI) in patients with thrombotic microangiopathy.
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| Yamashita Y, Naitoh K, Wada H, Ikejiri M, Mastumoto T, Ohishi K, Hosaka Y, Nishikawa M, Katayama N.
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| Thromb Res 133(3):440-4. doi: 10.1016/j.thromres.2013.11.023. Epub 2013 Dec 1.
2014
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| 11 | BSG, GP6
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| Circulating levels of soluble EMMPRIN (CD147) correlate with levels of soluble glycoprotein VI in human plasma.
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| Pennings GJ, Yong AS, Wong C, Al-Tamimi M, Gardiner EE, Andrews RK, Kritharides L.
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| Platelets 25(8):639-42. doi: 10.3109/09537104.2013.852660. Epub 2013 Nov 18.
2014
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| 12 | CLEC1B, GP6
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| Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice.
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| Bender M, May F, Lorenz V, Thielmann I, Hagedorn I, Finney BA, Vögtle T, Remer K, Braun A, Bösl M, Watson SP, Nieswandt B.
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| Arterioscler Thromb Vasc Biol 33(5):926-34. doi: 10.1161/ATVBAHA.112.300672. Epub 2013 Feb 28.
2013
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| 13 | GP6, PDLIM1
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| CLP36 is a negative regulator of glycoprotein VI signaling in platelets.
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| Gupta S, Braun A, Morowski M, Premsler T, Bender M, Nagy Z, Sickmann A, Hermanns HM, Bösl M, Nieswandt B.
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| Circ Res 111(11):1410-20. doi: 10.1161/CIRCRESAHA.112.264754. Epub 2012 Sep 5.
2012
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| 14 | GP6
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| Focusing on plasma glycoprotein VI.
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| Al-Tamimi M, Arthur JF, Gardiner E, Andrews RK.
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| Thromb Haemost 107(4):648-55. doi: 10.1160/TH11-10-0745. Epub 2012 Jan 25. Review.
2012
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| 15 | GP6, LYN, PECAM1, PTPN11
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| Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation.
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| Ming Z, Hu Y, Xiang J, Polewski P, Newman PJ, Newman DK.
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| Blood 117(14):3903-6. Epub 2011 Feb 4.
2011
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| 16 | GP6
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| Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke.
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| Al-Tamimi M, Gardiner EE, Thom JY, Shen Y, Cooper MN, Hankey GJ, Berndt MC, Baker RI, Andrews RK.
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| Stroke 42(2):498-500. Epub 2010 Dec 30.
2011
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| 17 | GP6, SYK, UBASH3B
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| A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets.
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| Thomas DH, Getz TM, Newman TN, Dangelmaier CA, Carpino N, Kunapuli SP, Tsygankov AY, Daniel JL.
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| Blood 116(14):2570-8. Epub 2010 Jun 28.PMID: 20585042 2010
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| 18 | GP6, SLA2
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| Roles of Src-like adaptor protein 2 (SLAP-2) in GPVI-mediated platelet activation SLAP-2 and GPVI signaling.
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| Sugihara S, Katsutani S, Deckmyn H, Fujimura K, Kimura A.
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| Thromb Res 126(4):e276-85. Epub 2010 Sep 15.
2010
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| 19 | GP6
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| Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases.
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| Bender M, Hofmann S, Stegner D, Chalaris A, Bösl M, Braun A, Scheller J, Rose-John S, Nieswandt B.
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| Blood 116(17):3347-55. Epub 2010 Jul 19.
2010
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| 20 | GP6
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| Diagnostic and therapeutic potentials of platelet glycoprotein VI.
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| Bigalke B, Krämer BF, Seizer P, Fateh-Moghadam S, Gawaz M, Lindemann S.
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| Semin Thromb Hemost 36(2):203-11. Epub 2010 Apr 22. Review.
2010
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| 21 | GP6
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| Platelet glycoprotein VI (GPVI) for early identification of acute coronary syndrome in patients with chest pain.
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| Bigalke B, Haap M, Stellos K, Geisler T, Seizer P, Kremmer E, Overkamp D, Gawaz M.
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| Thromb Res 125(5):e184-9. Epub 2010 Feb 1.
2010
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| 22 | BSG, GP6
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| EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction.
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| Seizer P, Borst O, Langer HF, Bültmann A, Münch G, Herouy Y, Stellos K, Krämer B, Bigalke B, Büchele B, Bachem MG, Vestweber D, Simmet T, Gawaz M, May AE.
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| Thromb Haemost 101(4):682-6.PMID: 19350111 2009
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| 23 | GP6, LYN
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| Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
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| Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML.
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| Proc Natl Acad Sci U S A 106(50):21167-72. Epub 2009 Nov 25.
2009
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| 24 | GP6
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| More on: glycoprotein VI oligomerization: a novel concept of platelet inhibition.
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| Sigalov AB.
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| J Thromb Haemost 5(11):2310-2. No abstract available.
2007
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| 25 | GP6
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| Glycoprotein VI agonists have distinct dependences on the lipid raft environment.
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| Quinter PG, Dangelmaier CA, Quinton TM, Kunapuli SP, Daniel JL.
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| J Thromb Haemost 5(2):362-8. Epub 2006 Nov 10.
2007
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| 26 | GP6
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| Selective blockade of glycoprotein VI clustering on collagen helices.
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| O'Connor MN, Smethurst PA, Davies LW, Joutsi-Korhonen L, Onley DJ, Herr AB, Farndale RW, Ouwehand WH.
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| J Biol Chem 281(44):33505-10. Epub 2006 Sep 6.
2006
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| 27 | GP6
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| Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.
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| Lecut C, Arocas V, Ulrichts H, Elbaz A, Villeval JL, Lacapere JJ, Deckmyn H, Jandrot-Perrus M.
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| J Biol Chem 279(50):52293-9. Epub 2004 Oct 4. 2004
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| 28 | GP6, AKT1
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| Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI.
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| Barry FA, Gibbins JM.
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| J Biol Chem 277(15):12874-8. 2002
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| 29 | GP6
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| Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI.
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| Andrews RK, Suzuki-Inoue K, Shen Y, Tulasne D, Watson SP, Berndt MC.
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| Blood 99(11):4219-21. 2002
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| 30 | GP6
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| Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagen.
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| Miura Y, Takahashi T, Jung SM, Moroi M.
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| J Biol Chem 277(48):46197-204. 2002
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| 31 | FLI1, TBX1, GP6, SPI1
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| Cloning and analysis of the thrombopoietin-induced megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1.
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| Holmes ML, Bartle N, Eisbacher M, Chong BH.
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| J Biol Chem 277(50):48333-41. 2002
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| 32 | GP6
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| Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI.
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| Ezumi Y, Uchiyama T, Takayama H.
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| Biochem Biophys Res Commun 277(1):27-36. 2000
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| 33 | GP6
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| Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
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| Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL.
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| Blood 96(5):1798-807. 2000
|