Citations for
1GNB1, MRHS
Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures.
Petrovski S, Küry S, Myers CT, Anyane-Yeboa K, Cogné B, Bialer M, Xia F, Hemati P, Riviello J, Mehaffey M, Besnard T, Becraft E, Wadley A, Politi AR, Colombo S, Zhu X, Ren Z, Andrews I, Dudding-Byth T, Schneider AL, Wallace G; University of Washington Center for Mendelian Genomics, Rosen AB, Schelley S, Enns GM, Corre P, Dalton J, Mercier S, Latypova X, Schmitt S, Guzman E, Moore C, Bier L, Heinzen EL, Karachunski P, Shur N, Grebe T, Basinger A, Nguyen JM, Bézieau S, Wierenga K, Bernstein JA, Scheffer IE, Rosenfeld JA, Mefford HC, Isidor B, Goldstein DB.
Am J Hum Genet 98(5):1001-10. doi: 10.1016/j.ajhg.2016.03.011. Epub 2016 Apr 21. 2016
2GNB1, MRD42
Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures.
Petrovski S, Küry S, Myers CT, Anyane-Yeboa K, Cogné B, Bialer M, Xia F, Hemati P, Riviello J, Mehaffey M, Besnard T, Becraft E, Wadley A, Politi AR, Colombo S, Zhu X, Ren Z, Andrews I, Dudding-Byth T, Schneider AL, Wallace G; University of Washington Center for Mendelian Genomics, Rosen ABI, Schelley S, Enns GM, Corre P, Dalton J, Mercier S, Latypova X, Schmitt S, Guzman E, Moore C, Bier L, Heinzen EL, Karachunski P, Shur N, Grebe T, Basinger A, Nguyen JM, Bézieau S, Wierenga K, Bernstein JA, Scheffer IE, Rosenfeld JA, Mefford HC, Isidor B, Goldstein DB.
Am J Hum Genet 98(5):1001-1010. doi: 10.1016/j.ajhg.2016.03.011. Epub 2016 Apr 21. 2016
3GNB1, GNB2
Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, Gritsman K, Gotlib J, Deininger MW, Makishima H, Turley SJ, Javidi-Sharifi N, Maciejewski JP, Jaiswal S, Ebert BL, Rodig SJ, Tyner JW, Marto JA, Weinstock DM, Lane AA.
Nat Med 21(1):71-5. doi: 10.1038/nm.3751. Epub 2014 Dec 8. 2015
4GNB1, GNB2, PSMB2
Evaluation of reference genes for gene expression studies in human brown adipose tissue.
Taube M, Andersson-Assarsson JC, Lindberg K, Pereira MJ, Gäbel M, Svensson MK, Eriksson JW, Svensson PA.
Adipocyte 4(4):280-5. doi: 10.1080/21623945.2015.1039884. eCollection 2015 Oct-Dec. 2015
5GNB1, GNB2, GNB3, GNG2, GNGT1
Gβγ interacts with mTOR and promotes its activation.
Robles-Molina E, Dionisio-Vicuńa M, Guzmán-Hernández ML, Reyes-Cruz G, Vázquez-Prado J.
Biochem Biophys Res Commun 444(2):218-23. doi: 10.1016/j.bbrc.2014.01.044. Epub 2014 Jan 22. 2014
6GNB1
Guanine nucleotide binding protein β 1: a novel transduction protein with a possible role in human breast cancer.
Wazir U, Jiang WG, Sharma AK, Mokbel K.
Cancer Genomics Proteomics 10(2):69-73. 2013
7GNB1, GNGT1
Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration.
Lobanova ES, Finkelstein S, Skiba NP, Arshavsky VY.
Proc Natl Acad Sci U S A 110(24):9986-91. doi: 10.1073/pnas.1305521110. Epub 2013 May 28. 2013
8GNAT1, GNB1, PDE6G, RGS9, RHO, SLC24A1
Selection of Phototransduction Genes in Homo sapiens
Christopher M, Scheetz TE, Mullins RF, Abrŕmoff MD
Invest Ophthalmol Vis Sci. Aug 13;54(8):5489-96. doi: 10.1167/iovs.12-11454. 2013
9GNB1, GNG2
Gβγ signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity.
Xu H, Kardash E, Chen S, Raz E, Lin F.
Development 139(1):57-62. Epub 2011 Nov 17. 2012
10ARL3, GNB1, RP2
The X-linked retinitis pigmentosa protein RP2 facilitates G protein traffic.
Schwarz N, Novoselova TV, Wait R, Hardcastle AJ, Cheetham ME.
Hum Mol Genet 21(4):863-73. doi: 10.1093/hmg/ddr520. Epub 2011 Nov 9. 2012
11GNB1, GNG2, RACK1, WDR26
The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migration.
Sun Z, Tang X, Lin F, Chen S.
J Biol Chem 286(51):43902-12. Epub 2011 Nov 7. 2011
12GNB1, GNG2, RAPGEF3
Gβγ subunits inhibit Epac-induced melanoma cell migration.
Baljinnyam E, Umemura M, De Lorenzo MS, Xie LH, Nowycky M, Iwatsubo M, Chen S, Goydos JS, Iwatsubo K.
BMC Cancer 11:256. doi: 10.1186/1471-2407-11-256. 2011
13GNB1, GNG2, RADIL, RAP1A
G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil.
Ahmed SM, Daulat AM, Meunier A, Angers S.
J Biol Chem 285(9):6538-51. Epub 2010 Jan 4. 2010
14GNB1, GNB2
Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.
Zhang Y, Tang W, Jones MC, Xu W, Halene S, Wu D.
J Biol Chem 285(32):24805-14. Epub 2010 Jun 4. 2010
15GNB1
Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.
Okae H, Iwakura Y.
Dev Dyn 239(4):1089-101. 2010
16ARRB1, GNB1, GNG2, GNGT2
beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation.
Yang M, He RL, Benovic JL, Ye RD.
Biochem J 417(1):287-96. 2009
17GNB1, PTK2
The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin.
Knezevic N, Tauseef M, Thennes T, Mehta D.
J Exp Med 206(12):2761-77. Epub 2009 Nov 16. 2009
18GNB1, GNB2, GNB3, KCNJ6
Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels.
Chung HJ, Qian X, Ehlers M, Jan YN, Jan LY.
Proc Natl Acad Sci U S A 106(2):629-34. doi: 10.1073/pnas.0811615106. Epub 2008 Dec 31. 2009
19GNB1, PLEKHG2, RAC1
Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.
Ueda H, Nagae R, Kozawa M, Morishita R, Kimura S, Nagase T, Ohara O, Yoshida S, Asano T.
J Biol Chem 283(4):1946-53. Epub 2007 Nov 28. 2008
20GNB1
A screen for mutations in the transducin gene GNB1 in patients with autosomal dominant retinitis pigmentosa
.Mylvaganam GH, McGee TL, Berson EL, Dryja TP.
Mol Vis. 12:1496-8 2006
21GNB1
A screen for mutations in the transducin gene GNB1 in patients with autosomal dominant retinitis pigmentosa.
Mylvaganam GH, McGee TL, Berson EL, Dryja TP.
Mol Vis 12:1496-8. 2006
22ARHGEF18, GNB1, GNG2
G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
Niu J, Profirovic J, Pan H, Vaiskunaite R, Voyno-Yasenetskaya T.
Circ Res 93(9):848-56. Epub 2003 Sep 25. 2003
23GNB1, GNB2, GNB3, GNB4, GNB5, RACK1
Folding a WD repeat propeller. Role of highly conserved aspartic acid residues in the G protein beta subunit and Sec13.
Garcia-Higuera I, Gaitatzes C, Smith TF, Neer EJ.
J Biol Chem 273(15):9041-9. 1998
24GNAS, GNB1
Chromosomal assignment of two GTP binding protein subunit genes : the alpha subunit of adenylyl cyclase (GNAS) and the beta 1 polypeptide (GNB).
Modi WS, et al.
(HGM11) Cytogenet Cell Genet 58 : 1860. 1991
25GNB1, GNB3
Molecular cloning of beta-3, a third form of the G-protein beta-polypeptide.
Levine MA, et al.
Proc Natl Acad Sci U S A 87 : 2329-2333. 1990
26GNB1, GNB3
Chromosomal localization of the genes encoding two forms of the G protein beta polypeptide, beta-1 and beta-3, in man.
Levine MA, et al.
Genomics 8 : 380-386. 1990
27GNAI1, GNAI2, GNAI2L, GNAI3, GNAZ, GNAS, GNAT1, GNAT2, GNB1, GNB2
Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.
Blatt C, Eversole-Cire P, Cohn VH, Zollman S, Fournier RE, Mohandas LT, Nesbitt M, Lugo T, Jones DT, Reed RR, et al.
Proc Natl Acad Sci U S A 85 : 7642-7646. 1988
28GNAT1, GNAT2, GNAI2, GNAI2L, GNAI3, GNAS, GNB1
Mapping of genes encoding the subunits of guanine nucleotide-binding proteins (G-proteins) in humans.
Sparkes RS, et al.
(HGM9) Cytogenet Cell Genet 46 : 696. 1987