| 1 | CCDC88A, GNAI3, PARD3
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| Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Gαi3 signaling.
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| Sasaki K, Kakuwa T, Akimoto K, Koga H, Ohno S.
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| J Cell Sci 128(13):2244-58. doi: 10.1242/jcs.160879. Epub 2015 May 14.
2015
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| 2 | GNAI2, GNAI3
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| Gαi2- and Gαi3-deficient mice display opposite severity of myocardial ischemia reperfusion injury.
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| Köhler D, Devanathan V, Bernardo de Oliveira Franz C, Eldh T, Novakovic A, Roth JM, Granja T, Birnbaumer L, Rosenberger P, Beer-Hammer S, Nürnberg B.
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| PLoS One 9(5):e98325. doi: 10.1371/journal.pone.0098325. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119092.
2014
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| 3 | GNAI2, GNAI3
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| The loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome.
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| Hwang IY, Park C, Luong T, Harrison KA, Birnbaumer L, Kehrl JH.
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| PLoS One 8(8):e72596. doi: 10.1371/journal.pone.0072596. eCollection 2013.
2013
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| 4 | GNAI2, GNAI3
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| Gαi2 is the essential Gαi protein in immune complex-induced lung disease.
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| Wiege K, Ali SR, Gewecke B, Novakovic A, Konrad FM, Pexa K, Beer-Hammer S, Reutershan J, Piekorz RP, Schmidt RE, Nürnberg B, Gessner JE.
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| J Immunol 190(1):324-33. doi: 10.4049/jimmunol.1201398. Epub 2012 Dec 5.
2013
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| 5 | ACDS1, ACDS2, GNAI3, PLCB4
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| A Human Homeotic Transformation Resulting from Mutations in PLCB4 and GNAI3 Causes Auriculocondylar Syndrome.
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| Rieder MJ, Green GE, Park SS, Stamper BD, Gordon CT, Johnson JM, Cunniff CM, Smith JD, Emery SB, Lyonnet S, Amiel J, Holder M, Heggie AA, Bamshad MJ, Nickerson DA, Cox TC, Hing AV, Horst JA, Cunningham ML.
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| Am J Hum Genet 90(5):907-14.
2012
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| 6 | GNAI1, GNAI2, GNAI3
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| Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins.
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| Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, Nürnberg B, Birnbaumer L.
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| Proc Natl Acad Sci U S A 109(52):21366-71. doi: 10.1073/pnas.1219810110. Epub 2012 Dec 11.
2012
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| 7 | GNAI3, KMT2D, SGK1
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| Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
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| Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD, Johnson NA, Severson TM, Chiu R, Field M, Jackman S, Krzywinski M, Scott DW, Trinh DL, Tamura-Wells J, Li S, Firme MR, Rogic S, Griffith M, Chan S, Yakovenko O, Meyer IM, Zhao EY, Smailus D, Moksa M, Chittaranjan S, Rimsza L, Brooks-Wilson A, Spinelli JJ, Ben-Neriah S, Meissner B, Woolcock B, Boyle M, McDonald H, Tam A, Zhao Y, Delaney A, Zeng T, Tse K, Butterfield Y, Birol I, Holt R, Schein J, Horsman DE, Moore R, Jones SJ, Connors JM, Hirst M, Gascoyne RD, Marra MA.
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| Nature 476(7360):298-303. doi: 10.1038/nature10351. 2011
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| 8 | GNAI3, TNFAIP8, TNFAIP8L1, TNFAIP8L2
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| TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.
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| Lalibert� B, Wilson AM, Nafisi H, Mao H, Zhou YY, Daigle M, Albert PR.
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| J Cell Physiol 225(3):865-74. 2010
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| 9 | GNAI3
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| Activation of mast cells by trimeric G protein Gi3; coupling to the A3 adenosine receptor directly and upon T cell contact.
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| Baram D, Dekel O, Mekori YA, Sagi-Eisenberg R.
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| J Immunol 184(7):3677-88. Epub 2010 Feb 26.
2010
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| 10 | GNAI3, IGFBP5
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| Insulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of G{alpha}i3.
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| Flynn RS, Mahavadi S, Murthy KS, Kellum JM, Kuemmerle JF.
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| Am J Physiol Gastrointest Liver Physiol 297(6):G1232-8. Epub 2009 Oct 1.
2009
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| 11 | GNAI2, GNAI3
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| Requirement of Galphai in thymic homing and early T cell development.
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| Jin Y, Wu MX.
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| Mol Immunol 45(12):3401-10. Epub 2008 May 23.PMID: 18501427 2008
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| 12 | CCDC88A, GNAI3
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| Activation of Galphai3 triggers cell migration via regulation of GIV.
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| Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG.
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| J Cell Biol 182(2):381-93.
2008
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| 13 | GNAI1, GNAI3, RGS14
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| Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization.
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| Shu FJ, Ramineni S, Amyot W, Hepler JR.
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| Cell Signal 19(1):163-76. Epub 2006 Jul 25.PMID: 16870394 2007
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| 14 | GSD3, CDC42, MSUD2, FCER1A, GNAI3, GUCA2A, ITPKB, MATN1, MCL1, NGF, PRDX1, PTPN7, S100A10
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| A comprehensive view of human chromosome 1.
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| White PS, Sulman EP, Porter CJ, Matise TC.
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| Genome Res 9(10):978-88 1999
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| 15 | GNAI1, GNAI2, GNAI2L, GNAI3, GNAZ, GNAS, GNAT1, GNAT2, GNB1, GNB2
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| Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.
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| Blatt C, Eversole-Cire P, Cohn VH, Zollman S, Fournier RE, Mohandas LT, Nesbitt M, Lugo T, Jones DT, Reed RR, et al.
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| Proc Natl Acad Sci U S A 85 : 7642-7646. 1988
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| 16 | GNAT1, GNAT2, GNAI2, GNAI2L, GNAI3, GNAS, GNB1
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| Mapping of genes encoding the subunits of guanine nucleotide-binding proteins (G-proteins) in humans.
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| Sparkes RS, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 696. 1987
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| 17 | GNAI1, GNAI2, GNAI2L, GNAI3
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| The human genome encodes at least three non-allellic G proteins with alpha-i-type subunits.
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| Suki WN, et al.
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| FEBS Lett 220 : 187-192. 1987
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