Citations for
1GNA12
Preeclampsia is Associated with Decreased Methylation of the GNA12 Promoter.
Ye W, Shen L, Xiong Y, Zhou Y, Gu H, Yang Z.
Ann Hum Genet 80(1):7-10. doi: 10.1111/ahg.12136. Epub 2015 Nov 2. 2016
2GNA12, GNA13, RGS22
RGS22 inhibits pancreatic adenocarcinoma cell migration through the G12/13 α subunit/F-actin pathway.
Hu Y, Xing J, Chen L, Zheng Y, Zhou Z.
Oncol Rep 34(5):2507-14. doi: 10.3892/or.2015.4209. Epub 2015 Aug 19. 2015
3ADGRG1, GNA12, GNA13, RHOA
The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA.
Ackerman SD, Garcia C, Piao X, Gutmann DH, Monk KR.
Nat Commun 6:6122. doi: 10.1038/ncomms7122. 2015
4ADAM10, GNA12, PKD1
Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.
Xu JX, Lu TS, Li S, Wu Y, Ding L, Denker BM, Bonventre JV, Kong T.
Physiol Genomics 47(2):24-32. doi: 10.1152/physiolgenomics.00090.2014. Epub 2014 Dec 9. 2015
5GNA12, VWF
G protein-dependent basal and evoked endothelial cell vWF secretion.
Rusu L, Andreeva A, Visintine DJ, Kim K, Vogel SM, Stojanovic-Terpo A, Chernaya O, Liu G, Bakhshi FR, Haberichter SL, Iwanari H, Kusano-Arai O, Suzuki N, Hamakubo T, Kozasa T, Cho J, Du X, Minshall RD.
Blood 123(3):442-50. doi: 10.1182/blood-2013-03-489351. Epub 2013 Sep 30. 2014
6GNA12
Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.
Boucher I, Yu W, Beaudry S, Negoro H, Tran M, Pollak MR, Henderson JM, Denker BM.
Lab Invest 92(5):662-75. doi: 10.1038/labinvest.2011.198. Epub 2012 Jan 16. 2012
7GNA12, MAPK8, ROCK1
G12 signaling through c-Jun NH2-terminal kinase promotes breast cancer cell invasion.
Juneja J, Cushman I, Casey PJ.
PLoS One 6(11):e26085. doi: 10.1371/journal.pone.0026085. Epub 2011 Nov 7. 2011
8DRD3, GNA12, GNA13
Role of Gα(12)- and Gα(13)-protein subunit linkage of D(3) dopamine receptors in the natriuretic effect of D(3) dopamine receptor in kidney.
Zhang Y, Fu C, Asico LD, Villar VA, Ren H, He D, Wang Z, Yang J, Jose PA, Zeng C.
Hypertens Res 34(9):1011-6. doi: 10.1038/hr.2011.70. Epub 2011 Jun 2. 2011
9GNA12, PKD1
Identification of polycystin-1 and Gα12 binding regions necessary for regulation of apoptosis.
Yu W, Ritchie BJ, Su X, Zhou J, Meigs TE, Denker BM.
Cell Signal 23(1):213-21. doi: 10.1016/j.cellsig.2010.09.005. Epub 2010 Sep 17. 2011
10GNA12
Galpha12 is critical for TCR-induced IL-2 production and differentiation of T helper 2 and T helper 17 cells.
Won HY, Min HJ, Lee WH, Kim SG, Hwang ES.
Biochem Biophys Res Commun 394(3):811-6. doi: 10.1016/j.bbrc.2010.03.079. Epub 2010 Mar 15. 2010
11GNA12
Galpha12 is critical for TCR-induced IL-2 production and differentiation of T helper 2 and T helper 17 cells.
Won HY, Min HJ, Lee WH, Kim SG, Hwang ES.
Biochem Biophys Res Commun 394(3):811-6. doi: 10.1016/j.bbrc.2010.03.079. Epub 2010 Mar 15. 2010
12GNA12, GNA13
Role of G12 proteins in oncogenesis and metastasis.
Juneja J, Casey PJ.
Br J Pharmacol 158(1):32-40. doi: 10.1111/j.1476-5381.2009.00180.x. Epub 2009 Apr 30. Review. 2009
13GNA12
G alpha12 is targeted to the mitochondria and affects mitochondrial morphology and motility.
Andreeva AV, Kutuzov MA, Voyno-Yasenetskaya TA.
FASEB J 22(8):2821-31. Epub 2008 Mar 26. 2008
14GNA12
Galpha12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IkappaBalpha.
Yanamadala V, Negoro H, Gunaratnam L, Kong T, Denker BM.
J Biol Chem 282(33):24352-63. Epub 2007 Jun 12. 2007
15GNA12
A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.
Kelly P, Stemmle LN, Madden JF, Fields TA, Daaka Y, Casey PJ.
J Biol Chem 281(36):26483-90. Epub 2006 Jun 20. 2006
16GNA12, GNA13
N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors.
Yamaguchi Y, Katoh H, Negishi M.
J Biol Chem 278(17):14936-9. Epub 2003 Feb 19. 2003
17GNA11P, GNA12, GNA13, GNAT3, GNG10, GNG11, GNG12, GNG2, GNG3, GNG4, GNG5P, GNG7, GNG8, GNG5P2
Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.
Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H.
DNA Res 7(2):111-20. 2000