Citations for
1GNA11, GNAQ
Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma.
Ayturk UM, Couto JA, Hann S, Mulliken JB, Williams KL, Huang AY, Fishman SJ, Boyd TK, Kozakewich HP, Bischoff J, Greene AK, Warman ML.
Am J Hum Genet 98(4):789-95. doi: 10.1016/j.ajhg.2016.03.009. 2016
2GNA11, GNA14
GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation.
Lim YH, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, Narayan D; Yale Center for Mendelian Genomics, McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate KA.
Am J Hum Genet 99(2):443-50. doi: 10.1016/j.ajhg.2016.06.010. Epub 2016 Jul 28. 2016
3GNA11, GNA14
Subcellular distribution patterns and elevated expression of GNA11 and GNA14 proteins in the lungs of humans with pulmonary arterial hypertension.
Lei W, Chen P, Yue Y, He Y, Shui X, Li G, Zhang L, Huang S, Chen C.
Cell Biol Int 38(9):1041-9. doi: 10.1002/cbin.10292. Epub 2014 May 19. 2014
4GNA11, GNAQ
The Gαq/11 proteins contribute to T lymphocyte migration by promoting turnover of integrin LFA-1 through recycling.
Svensson L, Stanley P, Willenbrock F, Hogg N.
PLoS One 7(6):e38517. doi: 10.1371/journal.pone.0038517. Epub 2012 Jun 11. 2012
5GNA11, NRAS
GNA11 and N-RAS mutations: alternatives for MAPK pathway activating GNAQ mutations in primary melanocytic tumours of the central nervous system.
Gessi M, Hammes J, Lauriola L, Dörner E, Kirfel J, Kristiansen G, Zur Muehlen A, Denkhaus D, Waha A, Pietsch T.
Neuropathol Appl Neurobiol europathol Appl Neurobiol. 2012 Jul 3. doi: 10.1111/j.1365-2990.2012.01288.x. [Epub ahead of print] 2012
6GNA11, GNAQ
Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.
Pahlavan S, Oberhofer M, Sauer B, Ruppenthal S, Tian Q, Scholz A, Kaestner L, Lipp P.
Cardiovasc Res 95(1):48-58. doi: 10.1093/cvr/cvs162. Epub 2012 May 4. 2012
7ADRBK1, GNA11, GNAQ
Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.
Lee IH, Song SH, Campbell CR, Kumar S, Cook DI, Dinudom A.
J Biol Chem 286(22):19259-69. doi: 10.1074/jbc.M111.239772. Epub 2011 Apr 4. 2011
8GNA11, GNAQ
Mutations in GNA11 in uveal melanoma.
Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S, Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, Sozen MM, Baimukanova G, Roy R, Heguy A, Dolgalev I, Khanin R, Busam K, Speicher MR, O'Brien J, Bastian BC.
N Engl J Med 363(23):2191-9. doi: 10.1056/NEJMoa1000584. Epub 2010 Nov 17. 2010
9GNA11, GNAQ, KISSiR
GPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Gα(q/11) and β-arrestin-dependent manner.
Szereszewski JM, Pampillo M, Ahow MR, Offermanns S, Bhattacharya M, Babwah AV.
PLoS One 5(9):e12964. doi: 10.1371/journal.pone.0012964. 2010
10GNA11, PECAM1
Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex.
Otte LA, Bell KS, Loufrani L, Yeh JC, Melchior B, Dao DN, Stevens HY, White CR, Frangos JA.
J Physiol 587(Pt 10):2365-73. Epub 2009 Mar 30.PMID: 19332487 2009
11GNA11, GNAQ
Anaphylactic shock depends on endothelial Gq/G11.
Korhonen H, Fisslthaler B, Moers A, Wirth A, Habermehl D, Wieland T, Schütz G, Wettschureck N, Fleming I, Offermanns S.
J Exp Med 206(2):411-20. doi: 10.1084/jem.20082150. Epub 2009 Jan 26. 2009
12GNA11
Phosphorylation of Galpha11 protein contributes to agonist-induced desensitization of 5-HT2A receptor signaling.
Shi J, Zemaitaitis B, Muma NA.
Mol Pharmacol 71(1):303-13. Epub 2006 Oct 20. 2007
13GNA11
Reduced expression of GNA11 and silencing of MCT1 in human breast cancers.
Asada K, Miyamoto K, Fukutomi T, Tsuda H, Yagi Y, Wakazono K, Oishi S, Fukui H, Sugimura T, Ushijima T.
Oncology 64(4):380-8. 2003
14GNAQ, GNA11, GNA14, VPS13A
Genomic organization of the human galpha14 and galphaq genes and mutation analysis in chorea-acanthocytosis.
Rubio JP, et al.
Genomics 57(1):84-93. 1999
15GNA11, GNA15, GNAT1, GNAT2
Evolution of the mammalian G protein alpha subunit multigene family.
Wilkie TM, et al.
Nat Genet 1 : 85-91. 1992
16GNAQ, GNA11, GNA14
Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.
Smrcka AV, et al.
Science 251(4995):804-7. 1991