| 1 | CASGID, GLS
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| GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay.
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| Rumping L, Tessadori F, Pouwels PJW, Vringer E, Wijnen JP, Bhogal AA, Savelberg SMC, Duran KJ, Bakkers MJG, Ramos RJJ, Schellekens PAW, Kroes HY, Klomp DWJ, Black GCM, Taylor RL, Bakkers JPW, Prinsen HCMT, van der Knaap MS, Dansen TB, Rehmann H, Zwartkruis FJT, Houwen RHJ, van Haaften G, Verhoeven-Duif NM, Jans JJM, van Hasselt PM.
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| Hum Mol Genet 28(1):96-104. doi: 10.1093/hmg/ddy330.
2019
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| 2 | EIEE71, GLS
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| Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy.
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| Rumping L, Büttner B, Maier O, Rehmann H, Lequin M, Schlump JU, Schmitt B, Schiebergen-Bronkhorst B, Prinsen HCMT, Losa M, Fingerhut R, Lemke JR, Zwartkruis FJT, Houwen RHJ, Jans JJM, Verhoeven-Duif NM, van Hasselt PM, Jamra R.
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| JAMA Neurol AMA Neurol. 2018 Dec 21. doi: 10.1001/jamaneurol.2018.2941. [Epub ahead of print]
2018
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| 3 | GLS, GLS2
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| Kidney-type glutaminase (GLS1) is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma.
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| Yu D, Shi X, Meng G, Chen J, Yan C, Jiang Y, Wei J, Ding Y.
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| Oncotarget 6(10):7619-31.
2015
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| 4 | GLS, GLS2
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| Expression of Gls and Gls2 glutaminase isoforms in astrocytes.
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| Cardona C, Sánchez-Mejías E, Dávila JC, Martín-Rufián M, Campos-Sandoval JA, Vitorica J, Alonso FJ, Matés JM, Segura JA, Norenberg MD, Rama Rao KV, Jayakumar AR, Gutiérrez A, Márquez J.
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| Glia 63(3):365-82. doi: 10.1002/glia.22758. Epub 2014 Oct 9.
2015
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| 5 | GLS, INSR, NCALD
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| Genes involved in muscle contractility and nutrient signaling pathways within celiac disease risk loci show differential mRNA expression.
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| Montén C, Gudjonsdottir AH, Browaldh L, Arnell H, Nilsson S, Agardh D, Naluai ÅT.
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| BMC Med Genet 16:44. doi: 10.1186/s12881-015-0190-1.
2015
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| 6 | GLS, GLS2
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| Opposing roles of glutaminase isoforms in determining glioblastoma cell phenotype.
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| Szeliga M, Albrecht J.
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| Neurochem Int eurochem Int. 2014 Dec 18. pii: S0197-0186(14)00230-7. doi: 10.1016/j.neuint.2014.11.004. [Epub ahead of print]
2014
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| 7 | GLS, GLS2
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| Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.
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| Lee YZ, Yang CW, Chang HY, Hsu HY, Chen IS, Chang HS, Lee CH, Lee JC, Kumar CR, Qiu YQ, Chao YS, Lee SJ.
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| Oncotarget 5(15):6087-101.
2014
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| 8 | GLS, GLS2
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| Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA).
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| Thangavelu K, Chong QY, Low BC, Sivaraman J.
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| Sci Rep 4:3827. doi: 10.1038/srep03827.
2014
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| 9 | GLS
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| Expression of glutaminase is upregulated in colorectal cancer and of clinical significance.
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| Huang F, Zhang Q, Ma H, Lv Q, Zhang T.
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| Int J Clin Exp Pathol 7(3):1093-100. eCollection 2014.
2014
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| 10 | GLS
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| IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase.
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| Ye L, Huang Y, Zhao L, Li Y, Sun L, Zhou Y, Qian G, Zheng JC.
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| J Neurochem 125(6):897-908. doi: 10.1111/jnc.12263. Epub 2013 May 3.
2013
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| 11 | GLS
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| The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
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| Yuneva MO, Fan TW, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T, Matés JM, Alonso FJ, Wang C, Seo Y, Chen X, Bishop JM.
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| Cell Metab 15(2):157-70. doi: 10.1016/j.cmet.2011.12.015.
2012
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| 12 | GLS, GLS2
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| Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
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| Thangavelu K, Pan CQ, Karlberg T, Balaji G, Uttamchandani M, Suresh V, Schüler H, Low BC, Sivaraman J.
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| Proc Natl Acad Sci U S A 109(20):7705-10. doi: 10.1073/pnas.1116573109. Epub 2012 Apr 26.
2012
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| 13 | GLS
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| Full-length human glutaminase in complex with an allosteric inhibitor.
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| DeLaBarre B, Gross S, Fang C, Gao Y, Jha A, Jiang F, Song J J, Wei W, Hurov JB.
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| Biochemistry 50(50):10764-70. doi: 10.1021/bi201613d. Epub 2011 Nov 18.
2011
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| 14 | GLS
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| Relationship between genetic variation in the glutaminase gene GLS1 and brain glutamine/glutamate ratio measured in vivo.
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| Öngür D, Haddad S, Prescot AP, Jensen JE, Siburian R, Cohen BM, Renshaw PF, Smoller JW.
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| Biol Psychiatry 70(2):169-74. doi: 10.1016/j.biopsych.2011.01.033. Epub 2011 Mar 31.
2011
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| 15 | GLS
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| Variations in the promoter region of the glutaminase gene and the development of hepatic encephalopathy in patients with cirrhosis: a cohort study.
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| Romero-Gómez M, Jover M, Del Campo JA, Royo JL, Hoyas E, Galán JJ, Montoliu C, Baccaro E, Guevara M, Córdoba J, Soriano G, Navarro JM, Martínez-Sierra C, Grande L, Galindo A, Mira E, Mañes S, Ruiz A.
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| Ann Intern Med 153(5):281-8. doi: 10.7326/0003-4819-153-5-201009070-00002.
2010
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| 16 | GLS
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| A novel glutaminase isoform in mammalian tissues.
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| de la Rosa V, Campos-Sandoval JA, Martín-Rufián M, Cardona C, Matés JM, Segura JA, Alonso FJ, Márquez J.
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| Neurochem Int 55(1-3):76-84. doi: 10.1016/j.neuint.2009.02.021. Epub 2009 Mar 9. Review.
2009
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| 17 | GLS
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| New insights into brain glutaminases: beyond their role on glutamatergic transmission.
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| Márquez J, Tosina M, de la Rosa V, Segura JA, Alonso FJ, Matés JM, Campos-Sandoval JA.
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| Neurochem Int 55(1-3):64-70. doi: 10.1016/j.neuint.2009.02.022. Epub 2009 Mar 9. Review.
2009
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| 18 | ATCAY, GLS
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| Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels.
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| Buschdorf JP, Li Chew L, Zhang B, Cao Q, Liang FY, Liou YC, Zhou YT, Low BC.
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| J Cell Sci 119(Pt 16):3337-50.
2006
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| 19 | GLS, GLS2
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| Co-expression of glutaminase K and L isoenzymes in human tumour cells.
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| Pérez-Gómez C, Campos-Sandoval JA, Alonso FJ, Segura JA, Manzanares E, Ruiz-Sánchez P, González ME, Márquez J, Matés JM.
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| Biochem J 386(Pt 3):535-42.
2005
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| 20 | GLS, GLS2
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| Identification of two human glutaminase loci and tissue-specific expression of the two related genes.
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| Aledo JC, Gomez-Fabre PM, Olalla L, Marquez J.
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| Mamm Genome 11(12):1107-10. 2000
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| 21 | APLP2, CAMK2B, CPB1, ENO1, VWF, GLS, ITPKC, LONP1, MTFN, PDE2A, PPP2R2A, MAP2K1L, RAB5B, SCN2A, TST
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| Toward a cDNA map of the human genome.
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| Korenberg JR, et al.
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| Genomics 29 : 364-370. 1995
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| 22 | GLS, IL9
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| Regional localization of the human glutaminase (GLS) and interleukin-9 (IL9) genes by in situ hybridization.
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| Modi WS, et al.
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| Cytogenet Cell Genet 57 : 114-116. 1991
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| 23 | GLS
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| A glutaminase (Gls) gene maps to mouse chromosome 1, rat chromosome 9, and human chromosome 2.
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| Mock B, Kozak C, Seldin MF, Ruff N, D'Hoostelaere L, Szpirer C, Levan G, Seuanez H, O'Brien S, Banner C.
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| Genomics 5 : 291-297. 1989
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