1 | ALDOA, BOLA2, CIAPIN1, GLRX3
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| The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and Anemia Predisposition in Chromosome 16p11.2 Autism Individuals.
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| Giannuzzi G, Schmidt PJ, Porcu E, Willemin G, Munson KM, Nuttle X, Earl R, Chrast J, Hoekzema K, Risso D, Männik K, De Nittis P, Baratz ED; 16p11.
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| Am J Hum Genet 105(5):947-958. doi: 10.1016/j.ajhg.2019.09.023. Epub 2019 Oct 24.
2019
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2 | EED, GLRX3
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| PICOT binding to the polycomb group protein, EED, alters H3K27 methylation at the MYT1 PRC2 target gene.
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| Pandya P, Pasvolsky R, Babichev Y, Braiman A, Witte S, Altman A, Isakov N.
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| Biochem Biophys Res Commun 509(2):469-475. doi: 10.1016/j.bbrc.2018.12.153. Epub 2018 Dec 27.
2019
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3 | BOLA2, GLRX3
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| Cytosolic iron chaperones: Proteins delivering iron cofactors in the cytosol of mammalian cells.
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| Philpott CC, Ryu MS, Frey A, Patel S.
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| J Biol Chem 292(31):12764-12771. doi: 10.1074/jbc.R117.791962. Epub 2017 Jun 14. Review.
2017
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4 | GLRX3
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| Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation.
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| Pham K, Dong J, Jiang X, Qu Y, Yu H, Yang Y, Olea W, Marini JC, Chan L, Wang J, Wehrens XH, Cui X, Li Y, Hadsell DL, Cheng N.
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| Am J Physiol Endocrinol Metab 312(3):E136-E149. doi: 10.1152/ajpendo.00150.2016. Epub 2016 Nov 15.
2017
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5 | BOLA2, GLRX3
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| A Glutaredoxin·BolA Complex Serves as an Iron-Sulfur Cluster Chaperone for the Cytosolic Cluster Assembly Machinery.
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| Frey AG, Palenchar DJ, Wildemann JD, Philpott CC.
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| J Biol Chem 291(43):22344-22356. doi: 10.1074/jbc.M116.744946. Epub 2016 Aug 12.
2016
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6 | BOLA2, GLRX3
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| Elucidating the Molecular Function of Human BOLA2 in GRX3-Dependent Anamorsin Maturation Pathway.
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| Banci L, Camponeschi F, Ciofi-Baffoni S, Muzzioli R.
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| J Am Chem Soc 137(51):16133-43. doi: 10.1021/jacs.5b10592. Epub 2015 Dec 16.
2015
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7 | GLRX3
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| Nuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell death.
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| Pham K, Pal R, Qu Y, Liu X, Yu H, Shiao SL, Wang X, O'Brian Smith E, Cui X, Rodney GG, Cheng N.
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| Free Radic Biol Med 85:197-206. doi: 10.1016/j.freeradbiomed.2015.05.003. Epub 2015 May 11.
2015
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8 | GLRX3
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| Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation.
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| Haunhorst P, Hanschmann EM, Bräutigam L, Stehling O, Hoffmann B, Mühlenhoff U, Lill R, Berndt C, Lillig CH.
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| Mol Biol Cell 24(12):1895-903. doi: 10.1091/mbc.E12-09-0648. Epub 2013 Apr 24.
2013
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9 | CASP3, GLRX3
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| Caspase-3-mediated cleavage of PICOT in apoptosis.
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| Yun N, Kim C, Cha H, Park WJ, Shibayama H, Park IS, Oh YJ.
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| Biochem Biophys Res Commun 432(3):533-8. doi: 10.1016/j.bbrc.2013.02.017. Epub 2013 Feb 13.
2013
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10 | BOLA2, GLRX3
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| Human glutaredoxin 3 forms [2Fe-2S]-bridged complexes with human BolA2.
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| Li H, Mapolelo DT, Randeniya S, Johnson MK, Outten CE.
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| Biochemistry 51(8):1687-96. doi: 10.1021/bi2019089. Epub 2012 Feb 10.
2012
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11 | CIAPIN1, GLRX3
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| PICOT is a molecule which binds to anamorsin.
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| Saito Y, Shibayama H, Tanaka H, Tanimura A, Matsumura I, Kanakura Y.
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| Biochem Biophys Res Commun 408(2):329-33. doi: 10.1016/j.bbrc.2011.04.033. Epub 2011 Apr 12.
2011
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12 | GLRX3
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| Characterization of the human monothiol glutaredoxin 3 (PICOT) as iron-sulfur protein.
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| Haunhorst P, Berndt C, Eitner S, Godoy JR, Lillig CH.
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| Biochem Biophys Res Commun 394(2):372-6. Epub 2010 Mar 10.
2010
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13 | GLRX3
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| Widespread expression of PICOT in mouse and human tissues with predominant localization to epithelium.
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| Ohayon A, Babichev Y, Galperin M, Altman A, Isakov N.
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| J Histochem Cytochem 58(9):799-806. doi: 10.1369/jhc.2010.956532. Epub 2010 May 24.
2010
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14 | GLRX3
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| PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.
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| Jeong D, Kim JM, Cha H, Oh JG, Park J, Yun SH, Ju ES, Jeon ES, Hajjar RJ, Park WJ.
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| Circ Res 102(6):711-9. Epub 2008 Feb 7.PMID: 18258855 2008
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15 | ACOT2, AFAP1L1, ALG11, ANKS1A, ARMC6, ARPC1A, ARPC3, ARPC5L, ATG10, ATP5L, BAZ1A, BCAS2, C2orf44, CAPZA1, CAPZA2, CCDC47, CERS2, CMBL, CPSF2, CSTF3, CXorf56, EXT2, FAF2, FBXO4, FIBP, GLRX3, GPS1, GSKIP, INPP5K, KPNA4, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT36, LUC7L2, MAGED1, MED7, MMS22L, MPRIP, MPRIP, MRCL3, NAA25, NDN, NPEPPS, NRDE2, OLA1, ORCTL3, OSTF1, PH4B, PIP5K1B, PKIG, PMVK, PSMC1, PSMC2, PSPH, RAB11FIP1, RBX1, RNF219, RO60, RPS14, SF3B14, SF3B2, SFRS12, STK25, TLK2, TONSL, TPM3, TRMT112, TSPAN17, TWF2, UBE2M, UNC45A, UQCRC1, WRAP73, XPO7, ZRANB2
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| Large-scale mapping of human protein-protein interactions by mass spectrometry.
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| Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D.
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| Mol Syst Biol 3:89. Epub 2007 Mar 13. 2007
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16 | GLRX3
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| PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractility.
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| Jeong D, Cha H, Kim E, Kang M, Yang DK, Kim JM, Yoon PO, Oh JG, Bernecker OY, Sakata S, Le TT, Cui L, Lee YH, Kim do H, Woo SH, Liao R, Hajjar RJ, Park WJ.
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| Circ Res 99(3):307-14. Epub 2006 Jun 29. 2006
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17 | ARIH1, DDX52, DIMT1, EIF5B, GLRX3, GPN1, LIAS, NFS1, NLE1, NSA2, NSUN5, TAF5L
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| Characterization of 16 novel human genes showing high similarity to yeast sequences.
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| Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N,Zimbello R, Lanfranchi G, Valle G.
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| Yeast 18(1):69-80. 2001
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18 | GLRX3
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| Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain.
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| Witte S, Villalba M, Bi K, Liu Y, Isakov N, Altman A.
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| J Biol Chem 275(3):1902-9. 2000
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