| 1 | ARHGEF6, ARHGEF7, GIT1, GIT2
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| Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.
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| Zhou W, Li X, Premont RT.
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| J Cell Sci 129(10):1963-74. doi: 10.1242/jcs.179465. Review. 2016
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| 2 | DOCK5, GIT2
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| The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.
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| Frank SR, Köllmann CP, van Lidth de Jeude JF, Thiagarajah JR, Engelholm LH, Frödin M, Hansen SH.
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| Oncogene ncogene. 2016 Sep 26. doi: 10.1038/onc.2016.345. [Epub ahead of print]
2016
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| 3 | GIT2, PXN, RUSC2
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| EGF-stimulated activation of Rab35 regulates RUSC2-GIT2 complex formation to stabilize GIT2 during directional lung cancer cell migration.
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| Duan B, Cui J, Sun S, Zheng J, Zhang Y, Ye B, Chen Y, Deng W, Du J, Zhu Y, Chen Y, Gu L.
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| Cancer Lett 379(1):70-83. doi: 10.1016/j.canlet.2016.05.027.
2016
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| 4 | GIT1, GIT2
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| Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse.
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| Montesinos MS, Dong W, Goff K, Das B, Guerrero-Given D, Schmalzigaug R, Premont RT, Satterfield R, Kamasawa N, Young SM Jr.
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| Neuron 88(5):918-25. doi: 10.1016/j.neuron.2015.10.042.
2015
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| 5 | ATM, GIT2, MRE11
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| Nuclear GIT2 is an ATM substrate and promotes DNA repair.
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| Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.
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| Mol Cell Biol 35(7):1081-96. doi: 10.1128/MCB.01432-14.
2015
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| 6 | ARHGEF7, GIT1, GIT2, RHOJ
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| RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.
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| Wilson E, Leszczynska K, Poulter NS, Edelmann F, Salisbury VA, Noy PJ, Bacon A, Rappoport JZ, Heath JK, Bicknell R, Heath VL.
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| J Cell Sci 127(Pt 14):3039-51. doi: 10.1242/jcs.140434.
2014
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| 7 | GIT2
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| The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling.
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| Wei J, Wei C, Wang M, Qiu X, Li Y, Yuan Y, Jin C, Leng L, Wang J, Yang X, He F.
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| Proc Natl Acad Sci U S A 111(24):8883-8. doi: 10.1073/pnas.1309218111.
2014
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| 8 | GIT2, VAV2
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| Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration.
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| Jones MC, Machida K, Mayer BJ, Turner CE.
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| Mol Biol Cell 24(12):1882-94. doi: 10.1091/mbc.E12-09-0654.
2013
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| 9 | ARHGEF6, GIT2
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| Biochemical and functional characterisation of αPIX, a specific regulator of axonal and dendritic branching in hippocampal neurons.
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| Totaro A, Tavano S, Filosa G, Gärtner A, Pennucci R, Santambrogio P, Bachi A, Dotti CG, de Curtis I.
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| Biol Cell 104(9):533-52. doi: 10.1111/boc.201100060.
2012
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| 10 | GIT2, PXN
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| Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migration.
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| Yu JA, Deakin NO, Turner CE.
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| Cell Adh Migr 4(3):342-7.
2010
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| 11 | GIT2
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| Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.
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| Yu JA, Deakin NO, Turner CE.
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| Mol Biol Cell 20(22):4706-19. doi: 10.1091/mbc.E09-07-0548.
2009
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| 12 | CRK, GIT2
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| GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover.
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| Frank SR, Adelstein MR, Hansen SH.
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| EMBO J 25(9):1848-59.
2006
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| 13 | GIT2, PTK2, SRC
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| Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.
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| Brown MC, Cary LA, Jamieson JS, Cooper JA, Turner CE.
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| Mol Biol Cell 16(9):4316-28.
2005
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| 14 | GIT2
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| An ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization.
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| Mazaki Y, Hashimoto S, Okawa K, Tsubouchi A, Nakamura K, Yagi R, Yano H,Kondo A, Iwamatsu A, Mizoguchi A, Sabe H.
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| Mol Biol Cell 12(3):645-62. 2001
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| 15 | GIT1, GIT2
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| The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing.
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| Premont RT, Claing A, Vitale N, Perry SJ, Lefkowitz RJ.
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| J Biol Chem 275(29):22373-80. 2000
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| 16 | GIT2
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| GIT proteins, A novel family of phosphatidylinositol 3,4, 5-trisphosphate-stimulated GTPase-activating proteins for ARF6.
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| Vitale N, Patton WA, Moss J, Vaughan M, Lefkowitz RJ, Premont RT.
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| J Biol Chem 275(18):13901-6. 2000
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| 17 | GIT2
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| A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.
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| Bagrodia S, Bailey D, Lenard Z, Hart M, Guan JL, Premont RT, Taylor SJ,Cerione RA.
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| J Biol Chem 274(32):22393-400. 1999
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| 18 | ARID4B, BOP1, CACNA2D2, CCT5, CKAP5, CTR9, DCLRE1A, DELE1, DGKD, DHX34, EIF3A, EIF4A3, EMC1, EMC2, EXOSC7, FAM175B, FAM53B, GANAB, GGA3, GIT2, GPD1L, INPP5E, KEAP1, KIAA0082, KIAA0087, KIAA0114, KIAA0125, MAD2L1BP, MBTPS1, METAP1, MORC3, NCAPD2, NUP93, OEATC1, PASK, PMPCA, PRDX6, PSMD6, PUM1, RBM10, SAFB2, SART3, SCRIB, SERTAD2, SNRK, SPCS2, TAGLN2, THRAP4, TRIM14, TTLL12, UBAP2L, UBE4A, URB2, ZC3H3
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| Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.
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| Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S,Ishikawa K, Kawarabayasi Y, Kotani H, et al.
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| DNA Res 2(1):37-43. 1995
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