1 | GHSR, MRAP2
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| The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a.
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| Rouault AAJ, Rosselli-Murai LK, Hernandez CC, Gimenez LE, Tall GG, Sebag JA.
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| Sci Signal. Jan 7;13(613):eaax4569. doi: 10.1126/scisignal.aax4569 2020
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2 | GHSR, LEAP2
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| LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
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| Ge X, Yang H, Bednarek MA, Galon-Tilleman H, Chen P, Chen M, Lichtman JS, Wang Y, Dalmas O, Yin Y, Tian H, Jermutus L, Grimsby J, Rondinone CM, Konkar A, Kaplan DD.
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| Cell Metab. Feb 6;27(2):461-469.e6. doi: 10.1016/j.cmet.2017.10.016. Epub 2017 Dec 7. 2018
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3 | CACNA1A, CACNA1B, GHSR
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| Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.
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| López Soto EJ, Agosti F, Cabral A, Mustafa ER, Damonte VM, Gandini MA, Rodríguez S, Castrogiovanni D, Felix R, Perelló M, Raingo J.
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| J Gen Physiol 146(3):205-19. doi: 10.1085/jgp.201511383.
2015
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4 | GHRL, GHSR
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| Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus.
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| Ribeiro LF, Catarino T, Santos SD, Benoist M, van Leeuwen JF, Esteban JA, Carvalho AL.
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| Proc Natl Acad Sci U S A 111(1):E149-58. doi: 10.1073/pnas.1313798111.
2014
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5 | GHSR
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| Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature.
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| Inoue H, Kangawa N, Kinouchi A, Sakamoto Y, Kimura C, Horikawa R, Shigematsu Y, Itakura M, Ogata T, Fujieda K; Japan Growth Genome Consortium.
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| J Clin Endocrinol Metab 96(2):E373-8. Epub 2010 Nov 17.
2011
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6 | GHRL, GHSR
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| Ghrelin inhibits proliferation and increases T-type Ca2+ channel expression in PC-3 human prostate carcinoma cells.
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| Díaz-Lezama N, Hernández-Elvira M, Sandoval A, Monroy A, Felix R, Monjaraz E.
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| Biochem Biophys Res Commun 403(1):24-9. Epub 2010 Oct 30.
2010
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7 | GHRL, GHSR
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| Altered myocardial expression of ghrelin and its receptor (GHSR-1a) in patients with severe heart failure.
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| Beiras-Fernandez A, Kreth S, Weis F, Ledderose C, Pöttinger T, Dieguez C, Beiras A, Reichart B.
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| Peptides 31(12):2222-8. Epub 2010 Sep 8.
2010
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8 | GHSR
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| Diminished endometrial expression of ghrelin and ghrelin receptor contributes to infertility.
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| Aghajanova L, Rumman A, Altmäe S, Wĺnggren K, Stavreus-Evers A.
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| Reprod Sci 17(9):823-32. Epub 2010 Jul 8.
2010
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9 | GHSR
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| In vivo characterization of high Basal signaling from the ghrelin receptor.
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| Petersen PS, Woldbye DP, Madsen AN, Egerod KL, Jin C, Lang M, Rasmussen M, Beck-Sickinger AG, Holst B.
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| Endocrinology 150(11):4920-30. Epub 2009 Oct 9.
2009
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10 | GHIS4, GHSR
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| Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor.
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| Pantel J, Legendre M, Nivot S, Morisset S, Vie-Luton MP, le Bouc Y, Epelbaum J, Amselem S.
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| J Clin Endocrinol Metab 94(11):4334-41. Epub 2009 Sep 29.
2009
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11 | GHRL, GHSR
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| Expression of ghrelin and its receptor in human tissues.
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| Ueberberg B, Unger N, Saeger W, Mann K, Petersenn S.
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| Horm Metab Res 41(11):814-21. Epub 2009 Aug 10.
2009
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12 | GHSR
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| Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance.
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| Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen AM, Lindström J, Eriksson JG, Carlberg C, Tuomilehto J, Uusitupa M; Finnish Diabetes Prevention Study Group.
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| PLoS One 3(8):e2941.
2008
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13 | GHSR
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| Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice.
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| Verhulst PJ, De Smet B, Saels I, Thijs T, Ver Donck L, Moechars D, Peeters TL, Depoortere I.
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| Gastroenterology 135(4):1267-76. Epub 2008 Jun 25.
2008
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14 | GHSR
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| The ghrelin system in acinar cells: localization, expression, and regulation in the exocrine pancreas.
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| Lai KC, Cheng CH, Leung PS.
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| Pancreas 35(3):e1-8.
2007
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15 | GHSR
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| Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.
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| Pantel J, Legendre M, Cabrol S, Hilal L, Hajaji Y, Morisset S, Nivot S, Vie-Luton MP, Grouselle D, de Kerdanet M, Kadiri A, Epelbaum J, Le Bouc Y, Amselem S.
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| J Clin Invest 116(3):760-8. 2006
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16 | GHSR
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| Genomic structure and transcriptional regulation of the human growth hormone secretagogue receptor.
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| Petersenn S, Rasch AC, Penshorn M, Beil FU, Schulte HM.
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| Endocrinology 142(6):2649-59. 2001
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17 | GHSR
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| Cloning and characterization of the 5'-flanking region of the human growth hormone secretagogue receptor gene.
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| Kaji H, et al.
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| J Biol Chem 273 : 33885-33888. 1998
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18 | GHSR
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| Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.
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| McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, Smith RG, Van der Ploeg LH, Howard AD.
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| Mol Endocrinol 11(4):415-23. 1997
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19 | GHSR
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| A receptor in pituitary and hypothalamus that functions in growth hormone release.
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| Howard AD, et al.
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| Science 273 : 974-977. 1996
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