| 1 | GFI1, ZC3H12C
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| Gfi1 and Zc3h12c orchestrate a negative feedback loop that inhibits NF-kB activation during inflammation in macrophages. 2020 PMID:
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| Guo G, Fu R, Zhang L, Chao T, Jiang Z, Dong L, Huang R, Lu L, Yang W, Gu Y, Liang Y, Zheng Q.
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| Mol Immunol. Dec;128:219-226. doi: 10.1016/j.molimm.2020.10.023. Epub 2020 Nov 3. 2020
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| 2 | GFI1, TLR7
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| The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.
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| Desnues B, Macedo AB, Ordoñez-Rueda D, Roussel-Queval A, Malissen B, Bruhns P, Malissen M, Alexopoulou L.
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| Eur J Immunol 46(12):2801-2811. doi: 10.1002/eji.201646573. Epub 2016 Oct 4.
2016
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| 3 | GFI1, GFI1B
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| From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation.
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| Möröy T, Vassen L, Wilkes B, Khandanpour C.
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| Blood 126(24):2561-9. doi: 10.1182/blood-2015-06-655043. Epub 2015 Oct 7. Review.
2015
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| 4 | GATA2, GFI1, MYSM1, RUNX1
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| The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation.
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| Wang T, Nandakumar V, Jiang XX, Jones L, Yang AG, Huang XF, Chen SY.
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| Blood 122(16):2812-22. doi: 10.1182/blood-2013-03-489641. Epub 2013 Sep 6.
2013
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| 5 | GFI1, GFI1B, RUNX1
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| GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.
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| Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, Vargel O, Wilson NK, Möröy T, Bonifer C, Göttgens B, Kouskoff V, Lacaud G.
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| Blood 120(2):314-22. doi: 10.1182/blood-2011-10-386094. Epub 2012 Jun 5.
2012
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| 6 | GFI1, GFI1B
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| Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1.
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| Schulz D, Vassen L, Chow KT, McWhirter SM, Amin RH, Möröy T, Schlissel MS.
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| J Exp Med 209(1):187-99. doi: 10.1084/jem.20110645. Epub 2011 Dec 26.
2012
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| 7 | GABPA, GFI1
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| GABP transcription factor is required for myeloid differentiation, in part, through its control of Gfi-1 expression.
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| Yang ZF, Drumea K, Cormier J, Wang J, Zhu X, Rosmarin AG.
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| Blood 118(8):2243-53. doi: 10.1182/blood-2010-07-298802. Epub 2011 Jun 24.
2011
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| 8 | GATA1, GFI1, HMGB2
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| High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription.
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| Laurent B, Randrianarison-Huetz V, Maréchal V, Mayeux P, Dusanter-Fourt I, Duménil D.
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| Blood 115(3):687-95. doi: 10.1182/blood-2009-06-230094. Epub 2009 Nov 24. Erratum in: Blood. 2010 Sep 2;116(9):1627. Marchal, Vincent 2010
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| 9 | GFI1, GFI1B
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| Gfi1 and Gfi1b: key regulators of hematopoiesis.
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| van der Meer LT, Jansen JH, van der Reijden BA.
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| Leukemia 24(11):1834-43. doi: 10.1038/leu.2010.195. Epub 2010 Sep 23. Review.
2010
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| 10 | CDKN2B, GFI1, ZBTB17
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| Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1.
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| Basu S, Liu Q, Qiu Y, Dong F.
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| Proc Natl Acad Sci U S A 106(5):1433-8. Epub 2009 Jan 22. 2009
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| 11 | ELANE, GFI1, N4BP2L2, SCNP2
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| Contributions to neutropenia from PFAAP5 (N4BP2L2), a novel protein mediating transcriptional repressor cooperation between Gfi1 and neutrophil elastase.
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| Salipante SJ, Rojas ME, Korkmaz B, Duan Z, Wechsler J, Benson KF, Person RE, Grimes HL, Horwitz MS.
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| Mol Cell Biol 29(16):4394-405. Epub 2009 Jun 8.PMID: 19506020 2009
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| 12 | AJUBA, GFI1
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| Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor.
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| Montoya-Durango DE, Velu CS, Kazanjian A, Rojas ME, Jay CM, Longmore GD, Grimes HL.
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| J Biol Chem 283(46):32056-65. Epub 2008 Sep 19. 2008
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| 13 | GFI1, GFI1B
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| Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis.
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| Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S.
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| Cell Res 18(6):677-85. doi: 10.1038/cr.2008.60.
2008
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| 14 | ARIH2, GFI1
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| Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1.
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| Marteijn JA, van der Meer LT, van Emst L, van Reijmersdal S, Wissink W, de Witte T, Jansen JH, Van der Reijden BA.
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| Blood 110(9):3128-35. Epub 2007 Jul 23.
2007
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| 15 | AJUBA, GFI1
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| The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling.
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| Ayyanathan K, Peng H, Hou Z, Fredericks WJ, Goyal RK, Langer EM, Longmore GD, Rauscher FJ 3rd.
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| Cancer Res 67(19):9097-106. 2007
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| 16 | GFI1, SGD
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| Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPepsilon gene.
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| Khanna-Gupta A, Sun H, Zibello T, Lee HM, Dahl R, Boxer LA, Berliner N.
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| Blood 109(10):4181-90. Epub 2007 Jan 23.
2007
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| 17 | EHMT2, GFI1
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| Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1.
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| Duan Z, Zarebski A, Montoya-Durango D, Grimes HL, Horwitz M.
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| Mol Cell Biol 25(23):10338-51. 2005
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| 18 | POU4F3, GFI1, ATOH1
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| Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene.
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| Hertzano R, Montcouquiol M, Rashi-Elkeles S, Elkon R, Yucel R, Frankel WN, Rechavi G, Moroy T, Friedman TB, Kelley MW, Avraham KB.
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| Hum Mol Genet 13(18):2143-53. Epub 2004 Jul 14. 2004
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| 19 | GFI1
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| Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells.
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| Hock H, Hamblen MJ, Rooke HM, Schindler JW, Saleque S, Fujiwara Y, Orkin SH.
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| Nature 431(7011):1002-7. Epub 2004 Sep 29. 2004
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| 20 | ELA2, ELANE, GFI1, SCNP2
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| Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2.
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| Person RE, Li FQ, Duan Z, Benson KF, Wechsler J, Papadaki HA, Eliopoulos G, Kaufman C, Bertolone SJ, Nakamoto B, Papayannopoulou T, Grimes HL, Horwitz M.
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| Nat Genet 34(3):308-12. 2003
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| 21 | GFI1
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| Cloning and characterization of the TATA-less promoter from the human GFI1 Proto-oncogene.
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| S. LIU a1 and J. K. COWELL.
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| Ann Hum Genet 64 : 83-86. 2000
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| 22 | GFI1
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| Cloning of the human Gfi-1 gene and its mapping to chromosome region 1p22.
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| Roberts T, et al.
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| Oncogene 14 : 1003-1005 1997
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| 23 | GFI1
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| Chromosomal localization of a gene, GFI1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents.
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| Bell DW, et al.
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| Cytogenet Cell Genet 70 : 263-267. 1995
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