Citations for
1BMP15, GDF9, POF14
Association of BMP15 and GDF9 variants to premature ovarian insufficiency
Santos M, Cordts EB, Peluso C, Dornas M, Neto FHV, Bianco B, Barbosa CP, Christofolini DM.
J Assist Reprod Genet. Oct;36(10):2163-2169. doi: 10.1007/s10815-019-01548-0. Epub 2019 Aug 7 2019
2GDF9, POF14
Identification of the first homozygous 1-bp deletion in GDF9 gene leading to primary ovarian insufficiency by using targeted massively parallel sequencing
França MM, Funari MFA, Nishi MY, Narcizo AM, Domenice S, Costa EMF, Lerario AM, Mendonca BB.
Clin Genet. Feb;93(2):408-411. doi: 10.1111/cge.13156. Epub 2017 Dec 26. 2018
3AMH, BMP15, GDF9
Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells
Roy S, Gandra D, Seger C, Biswas A, Kushnir VA, Gleicher N, Kumar TR, Sen A.
Endocrinology Sep 1;159(9):3433-3445. doi: 10.1210/en.2018-00609. 2018
4BMP15, GDF9
BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.
Patiño LC, Walton KL, Mueller TD, Johnson KE, Stocker W, Richani D, Agapiou D, Gilchrist RB, Laissue P, Harrison CA
J Clin Endocrinol Metab. 7 Mar 1;102(3):1009-1019. doi: 10.1210/jc.2016-3503. 2017
5BMP15, GDF9
Signalling pathways involved in the synergistic effects of human growth differentiation factor 9 and bone morphogenetic protein 15
Reader KL, Mottershead DG, Martin GA, Gilchrist RB, Heath DA, McNatty KP, Juengel JL.
Reprod Fertil Dev. Mar;28(4):491-8. doi: 10.1071/RD14099. 2016
6GDF9, NOBOX
GDF9 is transiently expressed in oocytes before follicle formation in the human fetal ovary and is regulated by a novel NOBOX transcript
Bayne RA, Kinnell HL, Coutts SM, He J, Childs AJ, Anderson RA.
PLoS One. Mar 19;10(3):e0119819. doi: 10.1371/journal.pone.0119819. 2015
7GDF9, POF14
Identification of a duplication within the GDF9 gene and novel candidate genes for primary ovarian insufficiency (POI) by a customized high-resolution array comparative genomic hybridization platform
Norling A, Hirschberg AL, Rodriguez-Wallberg KA, Iwarsson E, Wedell A, Barbaro M.
Hum Reprod. Aug;29(8):1818-27. doi: 10.1093/humrep/deu149. Epub 2014 Jun 17. 2014
8BMP15, GDF9, GJA1
Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells
Chang HM, Cheng JC, Taylor E, Leung PC
Mol Hum Reprod. May;20(5):373-83. doi: 10.1093/molehr/gau001. Epub 2014 Jan 10. 2014
9BMP15, GDF9
Increased GDF9 and BMP15 mRNA levels in cumulus granulosa cells correlate with oocyte maturation, fertilization, and embryo quality in humans
Li Y, Li RQ, Ou SB, Zhang NF, Ren L, Wei LN, Zhang QX, Yang DZ.
Reprod Biol Endocrinol. Aug 20;12:81. doi: 10.1186/1477-7827-12-81. 2014
10BMP15, GDF9
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions
Peng J, Li Q, Wigglesworth K, Rangarajan A, Kattamuri C, Peterson RT, Eppig JJ, Thompson TB, Matzuk MM.
Proc Natl Acad Sci U S A. Feb 19;110(8):E776-85. doi: 10.1073/pnas.1218020110. Epub 2013 Feb 4. 2013
11BMP15, GDF9
Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.
Mottershead DG, Harrison CA, Mueller TD, Stanton PG, Gilchrist RB, McNatty KP.
Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):E2257. doi: 10.1073/pnas.1303459110. Epub 2013 May 6 2013
12GDF9
Identification of a mutation in GDF9 as a novel cause of diminished ovarian reserve in young women
Wang TT, Ke ZH, Song Y, Chen LT, Chen XJ, Feng C, Zhang D, Zhang RJ, Wu YT, Zhang Y, Sheng JZ, Huang HF
Hum Reprod. Sep;28(9):2473-81. doi: 10.1093/humrep/det291. Epub 2013 Jul 12. 2013
13BMP15, GDF9
Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15
Mottershead DG, Ritter LJ, Gilchrist RB.
Mol Hum Reprod. Mar;18(3):121-8. doi: 10.1093/molehr/gar056. Epub 2011 Sep 12. 2012
14GDF9
Activation of latent human GDF9 by a single residue change (Gly 391 Arg) in the mature domain
Simpson CM, Stanton PG, Walton KL, Chan KL, Ritter LJ, Gilchrist RB, Harrison CA.
Endocrinology. Mar;153(3):1301-10. doi: 10.1210/en.2011-1632. Epub 2012 Jan 10. 2012
15BMP15, GDF9
Integral role of GDF-9 and BMP-15 in ovarian function.
Otsuka F, McTavish KJ, Shimasaki S.
Mol Reprod Dev. Jan;78(1):9-21. doi: 10.1002/mrd.21265. Epub 2011 Jan 11. 2011
16FST, FSTL3, GDF9
Growth differentiation factor 9 (GDF9) suppresses follistatin and follistatin-like 3 production in human granulosa-lutein cells
Shi FT, Cheung AP, Huang HF, Leung PC.
PLoS One. 6(8):e22866. doi: 10.1371/journal.pone.0022866. Epub 2011 Aug 1. 2011
17BMP15, GDF9
Growth differentiating factor 9 (GDF9) and bone morphogenetic protein 15 both activate development of human primordial follicles in vitro, with seemingly more beneficial effects of GDF9
Kedem A, Fisch B, Garor R, Ben-Zaken A, Gizunterman T, Felz C, Ben-Haroush A, Kravarusic D, Abir R.
J Clin Endocrinol Metab. Aug;96(8):E1246-54. doi: 10.1210/jc.2011-0410. Epub 2011 Jun 1 2011
18GDF9
Expression of growth-differentiating factor 9 and its type 1 receptor in human ovaries.
Oron G, Fisch B, Ao A, Zhang XY, Farhi J, Ben-Haroush A, Kesseler-Icekson G, Abir R.
Reprod Biomed Online. Jul;21(1):109-17. doi: 10.1016/j.rbmo.2010.03.011. Epub 2010 Mar 15. Erratum in: Reprod Biomed Online. 2011 Jan;22(1):102. Harou 2010
19BMP15, GDF9
Expression of GDF-9, BMP-15 and their receptors in mammalian ovary follicles.2010
Sun RZ, Lei L, Cheng L, Jin ZF, Zu SJ, Shan ZY, Wang ZD, Zhang JX, Liu ZH.
J Mol Histol. Dec;41(6):325-32. doi: 10.1007/s10735-010-9294-2. Epub 2010 Sep 21. 2010
20BMP15, GDF9
Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function
Nicholls PK, Harrison CA, Gilchrist RB, Farnworth PG, Stanton PG
Endocrinology May;150(5):2481-90. doi: 10.1210/en.2008-1048. Epub 2008 Dec 23. 2009
21GDF9
Growth differentiation factor 9 enhances activin a-induced inhibin B production in human granulosa cells
Shi FT, Cheung AP, Leung PC.
Endocrinology Aug;150(8):3540-6. doi: 10.1210/en.2009-0267. Epub 2009 May 7. 2009
22GDF9
Characterization of recombinant human growth differentiation factor-9 signaling in ovarian granulosa cells.
Mottershead DG, Pulkki MM, Muggalla P, Pasternack A, Tolonen M, Myllymaa S, Korchynskyi O, Nishi Y, Yanase T, Lun S, Juengel JL, Laitinen M, Ritvos O.
Mol Cell Endocrinol 283(1-2):58-67. Epub 2007 Nov 19.PMID: 18162287 2008
23BMP15, GDF9
Mutational analysis of BMP15 and GDF9 as candidate genes for premature ovarian failure.
Chand AL, Ponnampalam AP, Harris SE, Winship IM, Shelling AN.
Fertil Steril 86(4):1009-12. 2006
24GDF9
Molecular characterization of the follicle defects in the growth differentiation factor 9-deficient ovary.
Elvin JA, et al.
Mol Endocrinol 13(6):1018-34. 1999
25GDF9
Paracrine actions of growth differentiation factor-9 in the mammalian ovary.
Elvin JA, et al.
Mol Endocrinol 13(6):1035-48. 1999
26BMP1, BMP15, BMP2, BMP3, GDF10, BMP4, BMP5, BMP6, BMP7, BMPR1A, BMPR1APS1, BMPR1B, BMPR2, GDF1, GDF2, GDF3, GDF5, MSTN, GDF9
Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.
Constam DB, Robertson EJ.
J Cell Biol 144(1):139-49. 1999
27GDF9
GDF-3 and GDF-9 : two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines.
McPherron AC, et al.
J Biol Chem 268 : 3444-3449. 1993