Citations for
The epigenetic modifier DNMT3A is necessary for proper otic placode formation.
Roellig D, Bronner ME.
Dev Biol 411(2):294-300. doi: 10.1016/j.ydbio.2016.01.034. 2016
2ETV4, ETV5, GBX2, TCF15
ETS-related Transcription Factors ETV4 and ETV5 Are Involved in Proliferation and Induction of Differentiation-associated Genes in Embryonic Stem (ES) Cells.
Akagi T, Kuure S, Uranishi K, Koide H, Costantini F, Yokota T.
J Biol Chem 290(37):22460-73. doi: 10.1074/jbc.M115.675595. Epub 2015 Jul 29. 2015
Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.
Inoue F, Kurokawa D, Takahashi M, Aizawa S.
Mol Cell Biol 32(13):2618-27. doi: 10.1128/MCB.00083-12. Epub 2012 May 7. 2012
Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes.
Chatterjee M, Li K, Chen L, Maisano X, Guo Q, Gan L, Li JY.
Development 139(24):4633-43. doi: 10.1242/dev.086991. Epub 2012 Nov 7. 2012
Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary.
Sunmonu NA, Li K, Guo Q, Li JY.
Development 138(4):725-34. 2011
The lineage contribution and role of Gbx2 in spinal cord development.
Luu B, Ellisor D, Zervas M.
PLoS One 6(6):e20940. Epub 2011 Jun 16. 2011
Evolutionarily conserved function of Gbx2 in anterior hindbrain development.
Burroughs-Garcia J, Sittaramane V, Chandrasekhar A, Waters ST.
Dev Dyn 240(4):828-38. doi: 10.1002/dvdy.22589. Epub 2011 Feb 28. 2011
The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.
Chen L, Chatterjee M, Li JY.
J Neurosci 30(44):14824-34. 2010
The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction.
Li B, Kuriyama S, Moreno M, Mayor R.
Development 136(19):3267-78. 2009
10GBX2, TBX1
Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm.
Calmont A, Ivins S, Van Bueren KL, Papangeli I, Kyriakopoulou V, Andrews WD, Martin JF, Moon AM, Illingworth EA, Basson MA, Scambler PJ.
Development 136(18):3173-83. 2009
Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus.
Chen L, Guo Q, Li JY.
Development 136(8):1317-26. Epub 2009 Mar 11. 2009
A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2.
Lauberth SM, Bilyeu AC, Firulli BA, Kroll KL, Rauchman M.
J Biol Chem 282(48):34858-68. Epub 2007 Sep 25. 2007
13GBX2, OTX2
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors.
Heimbucher T, Murko C, Bajoghli B, Aghaallaei N, Huber A, Stebegg R, Eberhard D, Fink M, Simeone A, Czerny T.
Mol Cell Biol 27(1):340-51. Epub 2006 Oct 23. 2007
Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling.
Lin Z, Cantos R, Patente M, Wu DK.
Development 132(10):2309-18. Epub 2005 Apr 13. 2005
gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain.
Kikuta H, Kanai M, Ito Y, Yamasu K.
Dev Dyn 228(3):433-50. 2003
Molecular genetic delineation of 2q37.3 deletion in autism and osteodystrophy: report of a case and of new markers for deletion screening by PCR.
Smith M, Escamilla JR, Filipek P, Bocian ME, Modahl C, Flodman P, Spence MA.
Cytogenet Cell Genet 94(1-2):15-22. 2001
Characterization and sequence analysis of the human homeobox-containing gene GBX2.
Lin X, et al.
Genomics 31 : 335-342. 1996
18EN1, EN2, GBX1, GBX2
The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosome 2 and 7 in humans.
Matsui T, et al.
FEBS Lett 336 : 107-110. 1993