| 1 | GATA6, PLS3, TWIST1
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| Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome.
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| Wong HK, Gibson H, Hake T, Geyer S, Frederickson J, Marcucci G, Caligiuri MA, Porcu P, Mishra A.
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| J Invest Dermatol 135(8):2084-92. doi: 10.1038/jid.2015.116. Epub 2015 Mar 25.
2015
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| 2 | FZD2, GATA6, HMGA2
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| Hmga2 is required for canonical WNT signaling during lung development.
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| Singh I, Mehta A, Contreras A, Boettger T, Carraro G, Wheeler M, Cabrera-Fuentes HA, Bellusci S, Seeger W, Braun T, Barreto G.
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| BMC Biol 12:21. doi: 10.1186/1741-7007-12-21.
2014
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| 3 | GATA6
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| Silencing of GATA6 suppresses SW1990 pancreatic cancer cell growth in vitro and up-regulates reactive oxygen species.
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| Chen WB, Huang FT, Zhuang YY, Tang J, Zhuang XH, Cheng WJ, Gu ZQ, Zhang SN.
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| Dig Dis Sci 58(9):2518-27. doi: 10.1007/s10620-013-2752-4. Epub 2013 Jul 6.
2013
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| 4 | GATA6
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| GATA6 predicts prognosis and hepatic metastasis of colorectal cancer.
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| Shen F, Li J, Cai W, Zhu G, Gu W, Jia L, Xu B.
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| Oncol Rep 30(3):1355-61. doi: 10.3892/or.2013.2544. Epub 2013 Jun 19.
2013
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| 5 | GATA6
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| First report of a de novo 18q11.2 microdeletion including GATA6 associated with complex congenital heart disease and renal abnormalities.
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| Bui PH, Dorrani N, Wong D, Perens G, Dipple KM, Quintero-Rivera F.
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| Am J Med Genet A 161A(7):1773-8. doi: 10.1002/ajmg.a.35974. Epub 2013 May 21.
2013
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| 6 | ASD9, GATA6
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| Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation.
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| Li J, Liu WD, Yang ZL, Yang YQ.
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| Int J Mol Med 30(4):783-90. doi: 10.3892/ijmm.2012.1068. Epub 2012 Jul 18.
2012
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| 7 | ASD9, GATA6
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| GATA6 loss-of-function mutation in atrial fibrillation.
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| Yang YQ, Li L, Wang J, Zhang XL, Li RG, Xu YJ, Tan HW, Wang XH, Jiang JQ, Fang WY, Liu X.
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| Eur J Med Genet 55(10):520-6. doi: 10.1016/j.ejmg.2012.06.007. Epub 2012 Jun 26.
2012
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| 8 | GATA6, XPO1
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| cAMP-dependent proteolysis of GATA-6 is linked to JNK-signaling pathway.
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| Ushijima H, Maeda M.
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| Biochem Biophys Res Commun 423(4):679-83. doi: 10.1016/j.bbrc.2012.06.013. Epub 2012 Jun 10.
2012
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| 9 | GATA4, GATA6
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| Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.
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| Bennett J, Wu YG, Gossen J, Zhou P, Stocco C.
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| Endocrinology 153(5):2474-85. doi: 10.1210/en.2011-1969. Epub 2012 Mar 20.
2012
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| 10 | GATA6
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| Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma.
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| Lin L, Bass AJ, Lockwood WW, Wang Z, Silvers AL, Thomas DG, Chang AC, Lin J, Orringer MB, Li W, Glover TW, Giordano TJ, Lam WL, Meyerson M, Beer DG.
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| Proc Natl Acad Sci U S A 109(11):4251-6. doi: 10.1073/pnas.1011989109. Epub 2012 Feb 28.
2012
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| 11 | GATA4, GATA6
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| Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.
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| Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L.
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| J Clin Invest 122(10):3516-28. doi: 10.1172/JCI63352. Epub 2012 Sep 24.
2012
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| 12 | BMP2, GATA6
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| GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation.
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| Rong L, Liu J, Qi Y, Graham AM, Parmacek MS, Li S.
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| Mol Biol Cell 23(18):3754-63. doi: 10.1091/mbc.E12-04-0313. Epub 2012 Aug 1.
2012
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| 13 | AGT, GATA6
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| Angiotensin II induces apoptosis in intestinal epithelial cells through the AT2 receptor, GATA-6 and the Bax pathway.
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| Sun L, Wang W, Xiao W, Liang H, Yang Y, Yang H.
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| Biochem Biophys Res Commun 424(4):663-8. doi: 10.1016/j.bbrc.2012.07.003. Epub 2012 Jul 7.
2012
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| 14 | BMI1, GATA6
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| Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.
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| Lavial F, Bessonnard S, Ohnishi Y, Tsumura A, Chandrashekran A, Fenwick MA, Tomaz RA, Hosokawa H, Nakayama T, Chambers I, Hiiragi T, Chazaud C, Azuara V.
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| Genes Dev 26(13):1445-58. doi: 10.1101/gad.188193.112. Epub 2012 Jun 19.
2012
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| 15 | GATA6, TGFBR1
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| GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.
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| Froese N, Kattih B, Breitbart A, Grund A, Geffers R, Molkentin JD, Kispert A, Wollert KC, Drexler H, Heineke J.
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| J Biol Chem 286(7):5680-90. Epub 2010 Dec 2.
2011
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| 16 | GATA4, GATA5, GATA6
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| GATA5 interacts with GATA4 and GATA6 in outflow tract development.
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| Laforest B, Nemer M.
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| Dev Biol 358(2):368-78. Epub 2011 Aug 4.
2011
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| 17 | GATA6
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| GATA6 haploinsufficiency causes pancreatic agenesis in humans.
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| Lango Allen H, Flanagan SE, Shaw-Smith C, De Franco E, Akerman I, Caswell R; International Pancreatic Agenesis Consortium, Ferrer J, Hattersley AT, Ellard S.
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| Nat Genet 44(1):20-2. doi: 10.1038/ng.1035.
2011
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| 18 | GATA6, OFTD
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| GATA transcription factors in congenital heart defects: a commentary on a novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect.
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| Kodo K, Yamagishi H.
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| J Hum Genet 55(10):637-8. Epub 2010 Aug 26. No abstract available.
2010
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| 19 | ASD9, GATA6, OFTD
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| A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect.
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| Lin X, Huo Z, Liu X, Zhang Y, Li L, Zhao H, Yan B, Liu Y, Yang Y, Chen YH.
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| J Hum Genet 55(10):662-7. Epub 2010 Jul 15. 2010
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| 20 | AVSD5, GATA6
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| Identification of GATA6 sequence variants in patients with congenital heart defects.
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| Maitra M, Koenig SN, Srivastava D, Garg V.
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| Pediatr Res 68(4):281-5. doi: 10.1203/00006450-201011001-00549.
2010
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| 21 | GATA6, PACHD
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| Pancreatic hypoplasia presenting with neonatal diabetes mellitus in association with congenital heart defect and developmental delay.
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| Balasubramanian M, Shield JP, Acerini CL, Walker J, Ellard S, Marchand M, Polak M, Vaxillaire M, Crolla JA, Bunyan DJ, Mackay DJ, Temple IK.
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| Am J Med Genet A 152A(2):340-6. doi: 10.1002/ajmg.a.33194.
2010
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| 22 | GATA6, OFTD, PLXNA2, SEMA3C
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| GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling.
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| Kodo K, Nishizawa T, Furutani M, Arai S, Yamamura E, Joo K, Takahashi T, Matsuoka R, Yamagishi H.
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| Proc Natl Acad Sci U S A 106(33):13933-8. Epub 2009 Aug 4. 2009
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| 23 | ELF1, GATA2, GATA3, GATA4, GATA6, TEK
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| Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
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| Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.
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| J Biol Chem 284(42):29109-24. Epub 2009 Aug 12.PMID: 19674970 2009
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| 24 | GATA6
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| Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer.
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| Kwei KA, Bashyam MD, Kao J, Ratheesh R, Reddy EC, Kim YH, Montgomery K, Giacomini CP, Choi YL, Chatterjee S, Karikari CA, Salari K, Wang P, Hernandez-Boussard T, Swarnalata G, van de Rijn M, Maitra A, Pollack JR.
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| PLoS Genet 4(5):e1000081.
2008
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| 25 | GATA6, LGR5
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| A role for GATA-6 in vertebrate chondrogenesis.
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| Alexandrovich A, Qureishi A, Coudert AE, Zhang L, Grigoriadis AE, Shah AM, Brewer AC, Pizzey JA.
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| Dev Biol 314(2):457-70. Epub 2007 Dec 8.PMID: 1819112 2008
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| 26 | GATA6, MECOM
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| Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors.
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| Qiu Y, Lynch J, Guo L, Yatsula B, Perkins AS, Michalak M.
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| Biochemistry 47(12):3697-704. Epub 2008 Feb 28.PMID: 18303859 2008
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| 27 | GATA6, TNC
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| GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts.
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| Ghatnekar A, Trojanowska M.
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| Biochim Biophys Acta 1779(3):145-51. Epub 2007 Dec 14.PMID: 18177748 2008
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| 28 | AQP5, GATA6
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| GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
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| Zhou B, Francis TA, Yang H, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z.
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| Am J Physiol Cell Physiol 295(5):C1141-50. Epub 2008 Sep 3.PMID: 18768929 2008
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| 29 | GATA6
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| GATA6 is an astrocytoma tumor suppressor gene identified by gene trapping of mouse glioma model.
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| Kamnasaran D, Qian B, Hawkins C, Stanford WL, Guha A.
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| Proc Natl Acad Sci U S A 104(19):8053-8. Epub 2007 Apr 26. 2007
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| 30 | GATA6
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| Transcription factor GATA-6 in the human adrenocortex: association with adrenal development and aging.
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| Nakamura Y, Suzuki T, Sasano H.
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| Endocr J 54(5):783-9. Epub 2007 Sep 4.PMID: 17785913 2007
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| 31 | GATA4, GATA6
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| A threshold of GATA4 and GATA6 expression is required for cardiovascular development.
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| Xin M, Davis CA, Molkentin JD, Lien CL, Duncan SA, Richardson JA, Olson EN.
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| Proc Natl Acad Sci U S A 103(30):11189-94. Epub 2006 Jul 17. 2006
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| 32 | GATA6, SEMA3C
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| GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis.
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| Lepore JJ, Mericko PA, Cheng L, Lu MM, Morrisey EE, Parmacek MS.
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| J Clin Invest 116(4):929-39. Epub 2006 Mar 23. 2006
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| 33 | GATA6
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| A conserved role for a GATA transcription factor in regulating epithelial innate immune responses.
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| Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, Tan MW.
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| Proc Natl Acad Sci U S A 103(38):14086-91. Epub 2006 Sep 12.
2006
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| 34 | GATA6, WNT2
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| Wnt2 is a direct downstream target of GATA6 during early cardiogenesis.
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| Alexandrovich A, Arno M, Patient RK, Shah AM, Pizzey JA, Brewer AC.
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| Mech Dev 123(4):297-311. Epub 2006 Apr 18.PMID: 16621466 2006
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| 35 | GATA6
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| Expression of GATA6 in the human and mouse central nervous system.
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| Kamnasaran D, Guha A.
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| Brain Res Dev Brain Res 160(1):90-5. Epub 2005 Sep 15. 2005
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| 36 | GATA6, LMCD1
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| LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding.
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| Rath N, Wang Z, Lu MM, Morrisey EE.
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| Mol Cell Biol 25(20):8864-73.
2005
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| 37 | GATA4, GATA5, GATA6
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| The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.
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| Molkentin JD.
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| J Biol Chem 275(50):38949-52. Review. No abstract available. 2000
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| 38 | GATA4, GATA6, ZFPM2
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| Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors.
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| Laitinen MP, Anttonen M, Ketola I, Wilson DB, Ritvos O, Butzow R, Heikinheimo M.
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| J Clin Endocrinol Metab 85(9):3476-83. 2000
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| 39 | GATA6, HNF4A
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| GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo.
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| Morrisey EE, Tang Z, Sigrist K, Lu MM, Jiang F, Ip HS, Parmacek MS.
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| Genes Dev 12(22):3579-90. 1998
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| 40 | GATA6
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| The human GATA-6 gene : structure, chromosomal location, and regulation of expression by tissue-specific and mitogen-responsive signals.
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| Suzuki E, et al.
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| Genomics 38 : 283-290. 1996
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