Citations for
1CBX7, GATA4, SOX11
Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration
Duan RS, Tang GB, Du HZ, Hu YW, Liu PP, Xu YJ, Zeng YQ, Zhang SF, Wang RY, Teng ZQ, Liu CM.
Cell Death Differ. Sep;25(9):1598-1611. doi: 10.1038/s41418-018-0064-0. Epub 2018 Feb 19. 2018
2BMP2, GATA4, LMO3
GATA4 and LMO3 balance angiocrine signaling and autocrine inflammatory activation by BMP2 in liver sinusoidal endothelial cells.
Olsavszky V, Ulbrich F, Singh S, Diett M, Sticht C, Schmid CD, Zierow J, Wohlfeil SA, Schledzewski K, Dooley S, Gaitantzi H, Breitkopf-Heinlein K, Géraud C, Goerdt S, Koch PS.
Gene 627:491-499. doi: 10.1016/j.gene.2017.06.051. Epub 2017 Jun 29. 2017
3GATA4, NFATC3, NR4A1
Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation.
Yan G, Zhu N, Huang S, Yi B, Shang X, Chen M, Wang N, Zhang GX, Talarico JA, Tilley DG, Gao E, Sun J.
Mol Cell Biol 35(19):3312-23. doi: 10.1128/MCB.00229-15. Epub 2015 Jul 20. 2015
4GATA4, SLC10A2
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4.
Out C, Patankar JV, Doktorova M, Boesjes M, Bos T, de Boer S, Havinga R, Wolters H, Boverhof R, van Dijk TH, Smoczek A, Bleich A, Sachdev V, Kratky D, Kuipers F, Verkade HJ, Groen AK.
J Hepatol 63(3):697-704. doi: 10.1016/j.jhep.2015.04.030. Epub 2015 May 27. 2015
5GATA4, SMARCD3, TBX5
Gata4, Tbx5 and Baf60c induce differentiation of adipose tissue-derived mesenchymal stem cells into beating cardiomyocytes
Li Q, Guo ZK, Chang YQ, Yu X, Li CX, Li H.
Int J Biochem Cell Biol. Sep;66:30-6. doi: 10.1016/j.biocel.2015.06.008. Epub 2015 Jun 10 2015
6GATA4, GSN, MAPK14, NPPB
Gelsolin (GSN) induces cardiomyocyte hypertrophy and BNP expression via p38 signaling and GATA-4 transcriptional factor activation.
Hu WS, Ho TJ, Pai P, Chung LC, Kuo CH, Chang SH, Tsai FJ, Tsai CH, Jie YC, Liou YM, Huang CY.
Mol Cell Biochem 390(1-2):263-70. doi: 10.1007/s11010-014-1977-7. Epub 2014 Feb 7. 2014
7GATA4, NODAL
The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease.
Warburton D, Ronemus M, Kline J, Jobanputra V, Williams I, Anyane-Yeboa K, Chung W, Yu L, Wong N, Awad D, Yu CY, Leotta A, Kendall J, Yamrom B, Lee YH, Wigler M, Levy D.
Hum Genet 133(1):11-27. doi: 10.1007/s00439-013-1353-9. 2014
8GATA4, ZFPM2
FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development.
Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC.
Dev Biol 395(1):50-61. doi: 10.1016/j.ydbio.2014.08.030. Epub 2014 Sep 6. 2014
9CMD1OO, GATA4
A novel GATA4 loss-of-function mutation responsible for familial dilated cardiomyopathy.
Zhao L, Xu JH, Xu WJ, Yu H, Wang Q, Zheng HZ, Jiang WF, Jiang JF, Yang YQ.
Int J Mol Med nt J Mol Med. 2013 Dec 23. doi: 10.3892/ijmm.2013.1600. [Epub ahead of print] 2013
10DLX5, GATA4, RUNX2
GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2.
Song I, Kim K, Kim JH, Lee YK, Jung HJ, Byun HO, Yoon G, Kim N.
BMB Rep MB Rep. 2013 Dec 22. pii: 2539. [Epub ahead of print] 2013
11GATA4
A study of the role of GATA4 polymorphism in cardiovascular metabolic disorders.
Muiya NP, Wakil SM, Tahir AI, Hagos S, Najai M, Gueco D, Al-Tassan N, Andres E, Mazher N, Meyer BF, Dzimiri N.
Hum Genomics 7(1):25. [Epub ahead of print] 2013
12GATA4, ZFPM2
The transcription factor GATA4 is required for follicular development and normal ovarian function.
Efimenko E, Padua MB, Manuylov NL, Fox SC, Morse DA, Tevosian SG.
Dev Biol 381(1):144-58. doi: 10.1016/j.ydbio.2013.06.004. Epub 2013 Jun 14. 2013
13GATA4, LRRC10, NKX2-5
Lrrc10 is a novel cardiac-specific target gene of Nkx2-5 and GATA4.
Brody MJ, Cho E, Mysliwiec MR, Kim TG, Carlson CD, Lee KH, Lee Y.
J Mol Cell Cardiol 62:237-46. doi: 10.1016/j.yjmcc.2013.05.020. Epub 2013 Jun 7. 2013
14GATA4
Gata4 blocks somatic cell reprogramming by directly repressing Nanog.
Serrano F, Calatayud CF, Blazquez M, Torres J, Castell JV, Bort R.
Stem Cells 31(1):71-82. doi: 10.1002/stem.1272. 2013
15CMD1N, GATA4
GATA4 loss-of-function mutation underlies familial dilated cardiomyopathy.
Li RG, Li L, Qiu XB, Yuan F, Xu L, Li X, Xu YJ, Jiang WF, Jiang JQ, Liu X, Fang WY, Zhang M, Peng LY, Qu XK, Yang YQ.
Biochem Biophys Res Commun 439(4):591-6. doi: 10.1016/j.bbrc.2013.09.023. Epub 2013 Sep 13. 2013
16CNOT6, CYFIP1, EDIL3, FDFT1, GATA4, GJA5, HAND2, NEIL2, NIPA1, NIPA2, TUBGCP5
Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease.
Soemedi R, Wilson IJ, Bentham J, Darlay R, Töpf A, Zelenika D, Cosgrove C, Setchfield K, Thornborough C, Granados-Riveron J, Blue GM, Breckpot J, Hellens S, Zwolinkski S, Glen E, Mamasoula C, Rahman TJ, Hall D, Rauch A, Devriendt K, Gewillig M, O' Sullivan J, Winlaw DS, Bu'lock F, Brook JD, Bhattacharya S, Lathrop M, Santibanez-Koref M, Cordell HJ, Goodship JA, Keavney BD.
Am J Hum Genet 91(3):489-501. Epub 2012 Aug 30. 2012
17DEL8P23, GATA4, SOX7
Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1.
Wat MJ, Beck TF, Hernández-García A, Yu Z, Veenma D, Garcia M, Holder AM, Wat JJ, Chen Y, Mohila CA, Lally KP, Dickinson M, Tibboel D, de Klein A, Lee B, Scott DA.
Hum Mol Genet 21(18):4115-25. Epub 2012 Jun 20. 2012
18DIH1, DIH2, GATA4, NR2F2
A family-based paradigm to identify candidate chromosomal regions for isolated congenital diaphragmatic hernia.
Arrington CB, Bleyl SB, Matsunami N, Bowles NE, Leppert TI, Demarest BL, Osborne K, Yoder BA, Byrne JL, Schiffman JD, Null DM, Digeronimo R, Rollins M, Faix R, Comstock J, Camp NJ, Leppert MF, Yost HJ, Brunelli L.
Am J Med Genet A 158A(12):3137-47. doi: 10.1002/ajmg.a.35664. Epub 2012 Nov 19. 2012
19DEL8P23, GATA4, SOX7
Congenital diaphragmatic hernia interval on chromosome 8p23.1 characterized by genetics and protein interaction networks.
Longoni M, Lage K, Russell MK, Loscertales M, Abdul-Rahman OA, Baynam G, Bleyl SB, Brady PD, Breckpot J, Chen CP, Devriendt K, Gillessen-Kaesbach G, Grix AW, Rope AF, Shimokawa O, Strauss B, Wieczorek D, Zackai EH, Coletti CM, Maalouf FI, Noonan KM, Park JH, Tracy AA, Lee C, Donahoe PK, Pober BR.
Am J Med Genet A 158A(12):3148-58. doi: 10.1002/ajmg.a.35665. Epub 2012 Nov 19. 2012
20GATA4, GATA6
Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.
Bennett J, Wu YG, Gossen J, Zhou P, Stocco C.
Endocrinology 153(5):2474-85. doi: 10.1210/en.2011-1969. Epub 2012 Mar 20. 2012
21GATA4, GATA6
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.
Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L.
J Clin Invest 122(10):3516-28. doi: 10.1172/JCI63352. Epub 2012 Sep 24. 2012
22CCND2, GATA4
Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.
Yamak A, Temsah R, Maharsy W, Caron S, Paradis P, Aries A, Nemer M.
Am J Physiol Heart Circ Physiol 303(8):H1057-66. doi: 10.1152/ajpheart.00250.2012. Epub 2012 Aug 24. 2012
23CCND2, GATA4
Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.
Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V.
PLoS Genet 8(5):e1002690. doi: 10.1371/journal.pgen.1002690. Epub 2012 May 10. 2012
24EPO, GATA4, SIRT1, TAL1
GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1).
Wang L, Jia Y, Rogers H, Wu YP, Huang S, Noguchi CT.
J Biol Chem 287(36):30157-69. doi: 10.1074/jbc.M112.376640. Epub 2012 Jul 7. 2012
25GATA4, PTK2, VCAM1
Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD.
J Cell Biol 197(7):907-19. doi: 10.1083/jcb.201109067. 2012
26GATA4, ZFPM2
SUMOylation regulates the transcriptional repression activity of FOG-2 and its association with GATA-4.
Perdomo J, Jiang XM, Carter DR, Khachigian LM, Chong BH.
PLoS One 7(11):e50637. doi: 10.1371/journal.pone.0050637. Epub 2012 Nov 30. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/3d7a3 2012
27GATA4, XYDSD
Loss-of-function mutation in GATA4 causes anomalies of human testicular development.
Lourenço D, Brauner R, Rybczynska M, Nihoul-Fékété C, McElreavey K, Bashamboo A.
Proc Natl Acad Sci U S A 108(4):1597-602. Epub 2011 Jan 10. 2011
28EDN1, GATA4, ZNF260
ZFP260 is an inducer of cardiac hypertrophy and a nuclear mediator of endothelin-1 signaling.
Komati H, Maharsy W, Beauregard J, Hayek S, Nemer M.
J Biol Chem 286(2):1508-16. Epub 2010 Nov 4. 2011
29DEL8P21, DEL8P23, GATA4, LVNC
Noncompaction of the left ventricular myocardium in a boy with a novel chromosome 8p23.1 deletion.
Blinder JJ, Martinez HR, Craigen WJ, Belmont J, Pignatelli RH, Jefferies JL.
Am J Med Genet A 155(9):2215-20. doi: 10.1002/ajmg.a.34129. Epub 2011 Aug 10. 2011
30ASD2, GATA4, ID2, SMAD4
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]
Moskowitz IP, Wang J, Peterson MA, Pu WT, Mackinnon AC, Oxburgh L, Chu GC, Sarkar M, Berul C, Smoot L, Robertson EJ, Schwartz R, Seidman JG, Seidman CE.
Proc Natl Acad Sci U S A 108(10):4006-11. Epub 2011 Feb 17. Erratum in: Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5921. 2011
31EPOR, GATA4
Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes.
Salisch S, Klar M, Thurisch B, Bungert J, Dame C.
J Cell Mol Med 15(9):1963-72. doi: 10.1111/j.1582-4934.2010.01193.x. 2011
32GATA4, GATA5, GATA6
GATA5 interacts with GATA4 and GATA6 in outflow tract development.
Laforest B, Nemer M.
Dev Biol 358(2):368-78. Epub 2011 Aug 4. 2011
33GATA4, ZFPM2
Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation.
Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG.
Dev Biol 353(2):229-41. doi: 10.1016/j.ydbio.2011.02.032. Epub 2011 Mar 6. 2011
34GATA4, GATA5, NKX2-5, TBX
A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects.
Posch MG, Gramlich M, Sunde M, Schmitt KR, Lee SH, Richter S, Kersten A, Perrot A, Panek AN, Al Khatib IH, Nemer G, Mégarbané A, Dietz R, Stiller B, Berger F, Harvey RP, Ozcelik C.
J Med Genet 47(4):230-5. Epub 2009 Sep 16. 2010
35GATA4, GATA5
Methylation of GATA-4 and GATA-5 and development of sporadic gastric carcinomas.
Wen XZ, Akiyama Y, Pan KF, Liu ZJ, Lu ZM, Zhou J, Gu LK, Dong CX, Zhu BD, Ji JF, You WC, Deng DJ.
World J Gastroenterol 16(10):1201-8.PMID: 20222162 2010
36DEL8P23, DIH2, GATA4
Chromosome 8p23.1 deletions as a cause of complex congenital heart defects and diaphragmatic hernia.
Wat MJ, Shchelochkov OA, Holder AM, Breman AM, Dagli A, Bacino C, Scaglia F, Zori RT, Cheung SW, Scott DA, Kang SH.
Am J Med Genet A 149A(8):1661-1677. [Epub ahead of print] 2009
37ASD2, GATA4
Genetic screening of 104 patients with congenitally malformed hearts revealed a fresh mutation of GATA4 in those with atrial septal defects.
Hamanoue H, Rahayuningsih SE, Hirahara Y, Itoh J, Yokoyama U, Mizuguchi T, Saitsu H, Miyake N, Hirahara F, Matsumoto N.
Cardiol Young 19(5):482-5. Epub 2009 Aug 13. 2009
38GATA4
GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system.
Agnihotri S, Wolf A, Picard D, Hawkins C, Guha A.
Oncogene 28(34):3033-46. Epub 2009 Jun 22. 2009
39GATA4, NKX2-5
Cardiac differentiation is driven by NKX2.5 and GATA4 nuclear translocation in tissue-specific mesenchymal stem cells.
Armiñán A, Gandía C, Bartual M, García-Verdugo JM, Lledó E, Mirabet V, Llop M, Barea J, Montero JA, Sepúlveda P.
Stem Cells Dev 18(6):907-18. 2009
40GATA4
Enhanced expression of transcription factor GATA-4 in inflammatory bowel disease and its possible regulation by TGF-beta1.
Haveri H, Ashorn M, Iltanen S, Wilson DB, Andersson LC, Heikinheimo M.
J Clin Immunol 29(4):444-53. Epub 2009 Apr 8. 2009
41GATA4, GATA5
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.
Hellebrekers DM, Lentjes MH, van den Bosch SM, Melotte V, Wouters KA, Daenen KL, Smits KM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker CA, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruïne AP, van Engeland M.
Clin Cancer Res 15(12):3990-7. Epub 2009 Jun 9. PMID: 19509152 2009
42GATA4, NKX2-5
NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.
Riazi AM, Takeuchi JK, Hornberger LK, Zaidi SH, Amini F, Coles J, Bruneau BG, Van Arsdell GS.
PLoS One 4(5):e5698. 2009
43GATA4
A negative feedback regulatory loop associates the tyrosine kinase receptor ERBB2 and the transcription factor GATA4 in breast cancer cells.
Hua G, Zhu B, Rosa F, Deblon N, Adélaïde J, Kahn-Perlès B, Birnbaum D, Imbert J.
Mol Cancer Res 7(3):402-14. Epub 2009 Mar 10. 2009
44ELF1, GATA2, GATA3, GATA4, GATA6, TEK
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.
J Biol Chem 284(42):29109-24. Epub 2009 Aug 12.PMID: 19674970 2009
45GATA4, TNNT1, ZFPM2
Cardiac expression of Tnnt1 requires the GATA4-FOG2 transcription complex.
Manuylov NL, Tevosian SG.
ScientificWorldJournal 9:575-87. doi: 10.1100/tsw.2009.75. 2009
46ASD2, ASD3, GATA4, ICHD, JAG1, MYH6, NKX2-5, NOTCH1, TBX1, TBX20, TBX5, TFAP2B, THRAP2
The developmental genetics of congenital heart disease.
Bruneau BG.
Nature 451(7181):943-8. 2008
47DEL8P23, GATA4
Two patients with atypical interstitial deletions of 8p23.1: mapping of phenotypical traits.
Paez MT, Yamamoto T, Hayashi K, Yasuda T, Harada N, Matsumoto N, Kurosawa K, Furutani Y, Asakawa S, Shimizu N, Matsuoka R.
Am J Med Genet A 146(9):1158-65. 2008
48BMP4, CRELD1, GATA4, NKX2-5
Mutations in GATA4, NKX2.5, CRELD1, and BMP4 are infrequently found in patients with congenital cardiac septal defects.
Posch MG, Perrot A, Schmitt K, Mittelhaus S, Esenwein EM, Stiller B, Geier C, Dietz R, Gessner R, Ozcelik C, Berger F.
Am J Med Genet A 146A(2):251-3. No abstract available. 2008
49GATA4, KDM5B
GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.
Rojas A, Kong SW, Agarwal P, Gilliss B, Pu WT, Black BL.
Mol Cell Biol 28(17):5420-31. Epub 2008 Jun 30. 2008
50AVSD4, GATA4
GATA4 mutations in 486 Chinese patients with congenital heart disease.
Zhang W, Li X, Shen A, Jiao W, Guan X, Li Z.
Eur J Med Genet 51(6):527-35. doi: 10.1016/j.ejmg.2008.06.005. Epub 2008 Jul 11. 2008
51GATA4, LHX9, ZFPM2
GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart development.
Smagulova FO, Manuylov NL, Leach LL, Tevosian SG.
BMC Dev Biol 8:67. doi: 10.1186/1471-213X-8-67. 2008
52ASD2, GATA4
Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease.
Schluterman MK, Krysiak AE, Kathiriya IS, Abate N, Chandalia M, Srivastava D, Garg V.
Am J Med Genet A 143(8):817-23. 2007
53GATA4
GATA4 sequence variants in patients with congenital heart disease.
Tomita-Mitchell A, Maslen CL, Morris CD, Garg V, Goldmuntz E.
J Med Genet 44(12):779-83. 2007
54GATA4, ZFPM2
Gata4 is necessary for normal pulmonary lobar development.
Ackerman KG, Wang J, Luo L, Fujiwara Y, Orkin SH, Beier DR.
Am J Respir Cell Mol Biol 36(4):391-7. Epub 2006 Dec 1. 2007
55AVSD4, GATA4
Spectrum of heart disease associated with murine and human GATA4 mutation.
Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT.
J Mol Cell Cardiol 43(6):677-85. Epub 2007 Jun 21. 2007
56GATA4, GATA6
A threshold of GATA4 and GATA6 expression is required for cardiovascular development.
Xin M, Davis CA, Molkentin JD, Lien CL, Duncan SA, Richardson JA, Olson EN.
Proc Natl Acad Sci U S A 103(30):11189-94. Epub 2006 Jul 17. 2006
57GATA4
Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.
Bisping E, Ikeda S, Kong SW, Tarnavski O, Bodyak N, McMullen JR, Rajagopal S, Son JK, Ma Q, Springer Z, Kang PM, Izumo S, Pu WT.
Proc Natl Acad Sci U S A 103(39):14471-6. Epub 2006 Sep 18. 2006
58BCL2, GATA4
Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo.
Kobayashi S, Lackey T, Huang Y, Bisping E, Pu WT, Boxer LM, Liang Q.
FASEB J 20(6):800-2. Epub 2006 Feb 9. 2006
59GATA4, GATA5
Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis.
Wakana K, Akiyama Y, Aso T, Yuasa Y.
Cancer Lett 241(2):281-8. Epub 2005 Dec 7.PMID: 1633773 2006
60ASD2, CSX, GATA4, NKX2-5
Phenotypes with GATA4 or NKX2.5 mutations in familial atrial septal defect.
Hirayama-Yamada K, Kamisago M, Akimoto K, Aotsuka H, Nakamura Y, Tomita H, Furutani M, Imamura S, Takao A, Nakazawa M, Matsuoka R.
Am J Med Genet A 135(1):47-52. 2005
61CRELD1, GATA4, AVSD2
CRELD1 and GATA4 gene analysis in patients with nonsyndromic atrioventricular canal defects.
Sarkozy A, Esposito G, Conti E, Digilio MC, Marino B, Calabro R, Pizzuti A, Dallapiccola B.
Am J Med Genet A 139A(3):236-238. 2005
62GATA4
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis.
Watt AJ, Battle MA, Li J, Duncan SA.
Proc Natl Acad Sci U S A 101(34):12573-8. Epub 2004 Aug 13. 2004
63GATA4, MEF2C, CTNNA3
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.
Vanpoucke G, Goossens S, De Craene B, Gilbert B, van Roy F, Berx G.
Nucleic Acids Res 32(14):4155-65. Print 2004. 2004
64NPPA, JARID2, GATA4, NKX2-5
Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.
Kim TG, Chen J, Sadoshima J, Lee Y.
Mol Cell Biol 24(23):10151-60. 2004
65GATA4, NFATC4, PPP3CA, PPP3CB
Polymorphisms of genes of the cardiac calcineurin pathway and cardiac hypertrophy.
Poirier O, Nicaud V, McDonagh T, Dargie HJ, Desnos M, Dorent R, Roizes G, Schwartz K, Tiret L, Komajda M, Cambien F.
Eur J Hum Genet 11(9):659-64. 2003
66CYP11A1, CYP11B1, CYP11B2, CYP17A1D, CYP19A1, GATA4, NR0B1, NR2F1, NR2F2, NR5A1, PCNA, COPS2
DAX1 and its network partners: exploring complexity in development.
Clipsham R, McCabe ER.
Mol Genet Metab 80(1-2):81-120. 2003
67ASD2, GATA4, TBX5
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5.
Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D.
Nature 424(6947):443-7. Epub 2003 Jul 6. 2003
68GATA4,GATA5,TBX20
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.
Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, Lai D, McDonald LP, Niederreither K, Dolle P, Bruneau BG, Zorn AM, Harvey RP.
Dev Biol 262(2):206-24. 2003
69CORIN, GATA4
Genomic structures of the human and murine corin genes and functional GATA elements in their promoters.
Pan J, Hinzmann B, Yan W, Wu F, Morser J, Wu Q.
J Biol Chem 277(41):38390-8. Epub 2002 Aug 01. 2002
70GATA4, ZFPM2
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors.
Crispino JD, Lodish MB, Thurberg BL, Litovsky SH, Collins T, Molkentin JD, Orkin SH.
Genes Dev 15(7):839-44. 2001
71HDR, GATA4
An HDR (hypoparathyroidism, deafness, renal dysplasia) syndrome locus maps distal to the DiGeorge syndrome region on 10p13/14.
Lichtner P, Konig R, Hasegawa T, Van Esch H, Meitinger T, Schuffenhauer S.
J Med Genet 37(1):33-7 2000
72GATA4
A minimal critical region of the 8p22-23 amplicon in esophageal adenocarcinomas defined using sequence tagged site-amplification mapping and quantitative polymerase chain reaction includes the GATA-4 gene.
Lin L, Aggarwal S, Glover TW, Orringer MB, Hanash S, Beer DG.
Cancer Res 60(5):1341-7. 2000
73GATA4, GATA5, GATA6
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.
Molkentin JD.
J Biol Chem 275(50):38949-52. Review. No abstract available. 2000
74GATA4, GATA6, ZFPM2
Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors.
Laitinen MP, Anttonen M, Ketola I, Wilson DB, Ritvos O, Butzow R, Heikinheimo M.
J Clin Endocrinol Metab 85(9):3476-83. 2000
75GATA4, DEL8P23
GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease.
Pehlivan T. et al
Am J Med Genet 83 : 201-206. 1999
76ZFPM2, GATA4
hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation.
Holmes M, Turner J, Fox A, Chisholm O, Crossley M, Chong B.
J Biol Chem 274(33):23491-8. 1999
77ZFPM2, GATA4
Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes.
Svensson EC, Tufts RL, Polk CE, Leiden JM.
Proc Natl Acad Sci U S A 96(3):956-61. 1999
78GATA4
Assignment of the human GATA4 gene to 8p23.1-p22 using fluorescence in situ hybridization analysis.
Huang WY, et al.
Cytogenet Cell Genet 72 : 217-218. 1996
79GATA4
Identification of a GATA motif in the cardiac alpha-myosin heavy-chain-encoding gene and isolation of a human GATA-4 cDNA.
Huang WY, et al.
Gene 155 : 219-223. 1995
80GATA4
Assignment of the transcription factor GATA4 gene to human chromosome 8 and mouse chromosome 14 : Gata4 is a candidate gene for Ds (disorganization).
White RA, et al.
Genomics 27 : 20-26. 1995
81GATA4
Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins.
Yamagata T, Nishida J, Sakai R, Tanaka T, Honda H, Hirano N, Mano H, Yazaki Y, Hirai H.
Mol Cell Biol 15(7):3830-9. 1995