1 | GATA3, POU2F1, POU2F1
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| Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region.
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| Kim K, Kim N, Lee GR.
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| PLoS One 11(2):e0148576. doi: 10.1371/journal.pone.0148576. eCollection 2016.
2016
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2 | GATA3, SERTAD2
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| The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation.
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| Qiang G, Kong HW, Fang D, McCann M, Yang X, Du G, Blüher M, Zhu J, Liew CW.
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| Nat Commun 7:11378. doi: 10.1038/ncomms11378.
2016
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3 | GATA3, TBX21
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| Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance.
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| Yu F, Sharma S, Edwards J, Feigenbaum L, Zhu J.
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| Nat Immunol 16(2):197-206. doi: 10.1038/ni.3053. Epub 2014 Dec 15.
2015
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4 | GATA3, GCM2, MAFB
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| Gata3 cooperates with Gcm2 and MafB to activate parathyroid hormone gene expression by interacting with SP1.
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| Han SI, Tsunekage Y, Kataoka K.
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| Mol Cell Endocrinol 411:113-20. doi: 10.1016/j.mce.2015.04.018.
2015
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5 | GATA3
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| GATA-3 dose-dependent checkpoints in early T cell commitment.
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| Scripture-Adams DD, Damle SS, Li L, Elihu KJ, Qin S, Arias AM, Butler RR 3rd, Champhekar A, Zhang JA, Rothenberg EV.
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| J Immunol 193(7):3470-91. doi: 10.4049/jimmunol.1301663. Epub 2014 Aug 29.
2014
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6 | GATA3, IT2M2A
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| Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells.
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| Tai TS, Pai SY, Ho IC.
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| PLoS One 9(5):e96535. doi: 10.1371/journal.pone.0096535. eCollection 2014.
2014
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7 | GATA3, ISL1
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| LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3.
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| Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, Zhang X, Evans SM, Cui Y, Cui S.
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| BMC Biol 12:25. doi: 10.1186/1741-7007-12-25.
2014
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8 | GATA3
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| GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis.
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| Masse I, Barbollat-Boutrand L, Kharbili ME, Berthier-Vergnes O, Aubert D, Lamartine J.
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| Arch Dermatol Res 306(2):201-8. doi: 10.1007/s00403-013-1435-5. Epub 2013 Dec 18.
2014
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9 | FOXA1, GATA3, KDM5B
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| Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes.
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| Zou MR, Cao J, Liu Z, Huh SJ, Polyak K, Yan Q.
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| J Biol Chem 289(25):17620-33. doi: 10.1074/jbc.M114.570853. Epub 2014 May 6.
2014
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10 | GATA3, SPINK5
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| Regulation of serine protease inhibitor Kazal type-5 (SPINK5) gene expression in the keratinocytes.
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| Le NA, Katsuyama M, Demura M, Tanii H, Katsuyama H, Saijoh K.
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| Environ Health Prev Med 19(4):307-13. doi: 10.1007/s12199-014-0393-7. Epub 2014 Jun 4.
2014
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11 | EBF1, GATA3
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| Transcriptional repression of Gata3 is essential for early B cell commitment.
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| Banerjee A, Northrup D, Boukarabila H, Jacobsen SE, Allman D.
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| Immunity 38(5):930-42. doi: 10.1016/j.immuni.2013.01.014. Epub 2013 May 16.
2013
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12 | GATA3, YY1
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| Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
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| Hwang SS, Kim YU, Lee S, Jang SW, Kim MK, Koh BH, Lee W, Kim J, Souabni A, Busslinger M, Lee GR.
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| Proc Natl Acad Sci U S A 110(1):276-81. doi: 10.1073/pnas.1214682110. Epub 2012 Dec 17.
2013
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13 | FGF10, GATA3
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| Gata3 directly regulates early inner ear expression of Fgf10.
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| Economou A, Datta P, Georgiadis V, Cadot S, Frenz D, Maconochie M.
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| Dev Biol 374(1):210-22. doi: 10.1016/j.ydbio.2012.11.028. Epub 2012 Dec 3.
2013
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14 | GATA3, TCF3
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| E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.
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| Xu W, Carr T, Ramirez K, McGregor S, Sigvardsson M, Kee BL.
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| Blood 121(9):1534-42. doi: 10.1182/blood-2012-08-449447. Epub 2013 Jan 7.
2013
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15 | DEL10PD, DGS2, GATA3, HDR
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| Clinical description of a patient carrying the smallest reported deletion involving 10p14 region.
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| Melis D, Genesio R, Boemio P, Del Giudice E, Cappuccio G, Mormile A, Ronga V, Conti A, Imperati F, Nitsch L, Andria G.
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| Am J Med Genet A 158A(4):832-5. doi: 10.1002/ajmg.a.34133. Epub 2012 Mar 9.
2012
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16 | BRCA1, GATA3
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| BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers.
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| Tkocz D, Crawford NT, Buckley NE, Berry FB, Kennedy RD, Gorski JJ, Harkin DP, Mullan PB.
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| Oncogene 31(32):3667-78. doi: 10.1038/onc.2011.531. Epub 2011 Nov 28.
2012
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17 | GATA3, HMMS, TRPS1
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| Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1.
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| Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B.
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| Nat Genet 44(6):709-13. doi: 10.1038/ng.2259.
2012
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18 | CXCL12, GATA3, IRX5, TRPS1
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| Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1.
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| Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B.
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| Nat Genet 44(6):709-13. doi: 10.1038/ng.2259.
2012
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19 | GATA3, HAND2
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| Cytokines inhibit norepinephrine transporter expression by decreasing Hand2.
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| Pellegrino MJ, Parrish DC, Zigmond RE, Habecker BA.
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| Mol Cell Neurosci 46(3):671-80. Epub 2011 Jan 15.
2011
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20 | CASP14, GATA3
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| Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.
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| Asselin-Labat ML, Sutherland KD, Vaillant F, Gyorki DE, Wu D, Holroyd S, Breslin K, Ward T, Shi W, Bath ML, Deb S, Fox SB, Smyth GK, Lindeman GJ, Visvader JE.
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| Mol Cell Biol 31(22):4609-22. Epub 2011 Sep 19.
2011
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21 | EOMES, GATA3
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| Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.
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| Endo Y, Iwamura C, Kuwahara M, Suzuki A, Sugaya K, Tumes DJ, Tokoyoda K, Hosokawa H, Yamashita M, Nakayama T.
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| Immunity 35(5):733-45.
2011
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22 | GATA3
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| GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.
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| Buza-Vidas N, Duarte S, Luc S, Bouriez-Jones T, Woll PS, Jacobsen SE.
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| Blood 118(5):1291-3. Epub 2011 Jun 13.
2011
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23 | CDX2, GATA3, TEAD4
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| Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2.
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| Ralston A, Cox BJ, Nishioka N, Sasaki H, Chea E, Rugg-Gunn P, Guo G, Robson P, Draper JS, Rossant J.
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| Development 137(3):395-403.PMID: 20081188 2010
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24 | CTBP1, CTBP2, GATA1, GATA2, GATA3, ZFPM1, ZFPM2
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| GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis.
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| Jack BH, Crossley M.
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| J Biol Chem 285(42):32405-14. Epub 2010 Aug 11.
2010
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25 | GATA3
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| Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells.
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| Stanelle J, Döring C, Hansmann ML, Küppers R.
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| Blood 116(20):4202-11. Epub 2010 Jul 26.
2010
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26 | GATA3, PVT1, REL
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| A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).
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| Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, van den Berg A, Olver B, Lloyd A, Dobbins SE, Lightfoot T, van Leeuwen FE, Försti A, Diepstra A, Broeks A, Vijayakrishnan J, Shield L, Lake A, Montgomery D, Roman E, Engert A, von Strandmann EP, Reiners KS, Nolte IM, Smedby KE, Adami HO, Russell NS, Glimelius B, Hamilton-Dutoit S, de Bruin M, Ryder LP, Molin D, Sorensen KM, Chang ET, Taylor M, Cooke R, Hofstra R, Westers H, van Wezel T, van Eijk R, Ashworth A, Rostgaard K, Melbye M, Swerdlow AJ, Houlston RS.
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| Nat Genet 42(12):1126-30. Epub 2010 Oct 31.
2010
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27 | GATA3, KLK1
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| Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3.
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| Son do N, Li L, Katsuyama H, Komatsu N, Saito M, Tanii H, Saijoh K.
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| Gene 436(1-2):121-7. Epub 2009 Feb 13.
2009
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28 | GATA3, HDR
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| HDR syndrome: a novel "de novo" mutation in GATA3 gene.
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| Ferraris S, Del Monaco AG, Garelli E, Carando A, De Vito B, Pappi P, Lala R, Ponzone A.
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| Am J Med Genet A 149A(4):770-5.
2009
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29 | GATA3, HDR
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| A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome.
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| Gaynor KU, Grigorieva IV, Nesbit MA, Cranston T, Gomes T, Gortner L, Thakker RV.
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| J Clin Endocrinol Metab 94(10):3897-904. Epub 2009 Sep 1.PMID: 19723756 2009
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30 | ELF1, GATA2, GATA3, GATA4, GATA6, TEK
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| Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
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| Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.
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| J Biol Chem 284(42):29109-24. Epub 2009 Aug 12.PMID: 19674970 2009
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31 | GATA3, TBX21
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| Cyclic regulation of T-Bet and GATA-3 in human endometrium.
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| Inman D, Kawana K, Schust D, Lininger R, Young S.
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| Reprod Sci 15(1):83-90.PMID: 18212358 2008
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32 | GATA3, HDR
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| Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor.
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| Ali A, Christie PT, Grigorieva IV, Harding B, Van Esch H, Ahmed SF, Bitner-Glindzicz M, Blind E, Bloch C, Christin P, Clayton P, Gecz J, Gilbert-Dussardier B, Guillen-Navarro E, Hackett A, Halac I, Hendy GN, Lalloo F, Mache CJ, Mughal Z, Ong AC, Rinat C, Shaw N, Smithson SF, Tolmie J, Weill J, Nesbit MA, Thakker RV.
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| Hum Mol Genet 16(3):265-75. Epub 2007 Jan 8. 2007
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33 | HDR, GATA3
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| Novel mutation in the gene encoding the GATA3 transcription factor in a Spanish familial case of hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome with female genital tract malformations.
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| Hernandez AM, Villamar M, Rosello L, Moreno-Pelayo MA, Moreno F, Del Castillo I.
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| Am J Med Genet A 143(7):757-62. No abstract available. 2007
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34 | GATA3,GFI1B,TCF3
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| Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas.
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| Wei X, Kee BL.
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| Blood 109(10):4406-14. Epub 2007 Feb 1. 2007
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35 | GATA3
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| Aberrant gata-3 expression in human pancreatic cancer.
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| Gulbinas A, Berberat PO, Dambrauskas Z, Giese T, Giese N, Autschbach F, Kleeff J, Meuer S, Buchler MW, Friess H.
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| J Histochem Cytochem 54(2):161-9. Epub 2005 Aug 8. 2006
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36 | GATA3
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| Transcription factor GATA-3 is involved in repression of promoter activity of the human interleukin-4 gene.
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| Schwenger GT, Mordvinov VA, Sanderson CJ.
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| Biochemistry (Mosc) 70(9):1065-9. 2005
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37 | STAT6, GATA3, KIF3A, IL4, IL13, RAD50
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| Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
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| Lee DU, Rao A.
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| Proc Natl Acad Sci U S A 101(45):16010-5. Epub 2004 Oct 26. 2004
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38 | GATA3, HDR
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| Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome.
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| Nesbit MA, Bowl MR, Harding B, Ali A, Ayala A, Crowe C, Dobbie A, Hampson G, Holdaway I, Levine MA, McWilliams R, Rigden S, Sampson J, Williams AJ, Thakker RV.
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| J Biol Chem 279(21):22624-34. Epub 2004 Feb 24. 2004
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39 | GATA3
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| Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human.
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| Asnagli H, Afkarian M, Murphy KM.
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| J Immunol 168(9):4268-71. 2002
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40 | GATA3
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| GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model.
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| Hofer T, Nathansen H, Lohning M, Radbruch A, Heinrich R.
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| Proc Natl Acad Sci U S A 99(14):9364-8. 2002
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41 | GATA3, HDR
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| GATA3 abnormalities and the phenotypic spectrum of HDR syndrome.
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| Muroya K, Hasegawa T, Ito Y, Nagai T, Isotani H, Iwata Y, Yamamoto K, Fujimoto S, Seishu S, Fukushima Y, Hasegawa Y, Ogata T.
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| J Med Genet 38(6):374-80. 2001
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42 | AIRE, GATA3, GCM2
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| Genetic developments in hypoparathyroidism.
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| Thakker RV.
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| Lancet 357(9261):974-6. No abstract available. 2001
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43 | GATA3, HDR
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| GATA3 haplo-insufficiency causes human HDR syndrome.
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| Van Esch H, Groenen P, Nesbit MA, Schuffenhauer S, Lichtner P, Vanderlinden G, Harding B, Beetz R, Bilous RW, Holdaway I, Shaw NJ, Fryns JP, Van de Ven W, Thakker RV, Devriendt K.
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| Nature 406(6794):419-22. 2000
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44 | GATA3
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| Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system.
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| Lim KC, Lakshmanan G, Crawford SE, Gu Y, Grosveld F, Engel JD.
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| Nat Genet 25(2):209-12. 2000
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45 | GATA3
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| Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus.
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| Lakshmanan G, et al.
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| Mol Cell Biol 19(2):1558-68. 1999
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46 | HDR, GATA3
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| Recurrent cerebral infarctions and del(10)(p14p15.1) de novo in HDR (hypoparathyroidism, sensorineural deafness, renal dysplasia) syndrome.
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| Fujimoto S, Yokochi K, Morikawa H, Nakano M, Shibata H, Togari H, Wada Y.
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| Am J Med Genet 86(5):427-9. 1999
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47 | GATA2, GATA3
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| GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes.
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| Elefanty AG, et al.
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| EMBO J 15 : 319-333. 1996
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48 | GATA3
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| Structure and expression of the human GATA3 gene.
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| Labastie MC, et al.
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| Genomics 21 : 1-6. 1994
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49 | GATA3
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| A T-cell specific TCR delta DNA binding protein is a member of the human GATA family.
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| Joulin V, et al.
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| EMBO J 10 : 1809-1816. 1991
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50 | GATA3, IL7R
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| 93.
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| The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells.
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| Yagi R, Zhong C, Northrup DL, Yu F, Bouladoux N, Spencer S, Hu G, Barron L, Sharma S, Nakayama T, Belkaid Y, Zhao K, Zhu J agi R, Zhong C, Northrup DL, Yu F, Bouladoux N, Spencer S, Hu G, Barron L, Sharma S, Nakayama T, Belkaid Y, Zhao K, Zhu J.
|