Citations for
1GATA3, POU2F1, POU2F1
Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region.
Kim K, Kim N, Lee GR.
PLoS One 11(2):e0148576. doi: 10.1371/journal.pone.0148576. eCollection 2016. 2016
2GATA3, SERTAD2
The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral fat endoplasmic reticulum stress-induced inflammation.
Qiang G, Kong HW, Fang D, McCann M, Yang X, Du G, Blüher M, Zhu J, Liew CW.
Nat Commun 7:11378. doi: 10.1038/ncomms11378. 2016
3GATA3, TBX21
Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance.
Yu F, Sharma S, Edwards J, Feigenbaum L, Zhu J.
Nat Immunol 16(2):197-206. doi: 10.1038/ni.3053. Epub 2014 Dec 15. 2015
4GATA3, GCM2, MAFB
Gata3 cooperates with Gcm2 and MafB to activate parathyroid hormone gene expression by interacting with SP1.
Han SI, Tsunekage Y, Kataoka K.
Mol Cell Endocrinol 411:113-20. doi: 10.1016/j.mce.2015.04.018. 2015
5GATA3
GATA-3 dose-dependent checkpoints in early T cell commitment.
Scripture-Adams DD, Damle SS, Li L, Elihu KJ, Qin S, Arias AM, Butler RR 3rd, Champhekar A, Zhang JA, Rothenberg EV.
J Immunol 193(7):3470-91. doi: 10.4049/jimmunol.1301663. Epub 2014 Aug 29. 2014
6GATA3, IT2M2A
Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells.
Tai TS, Pai SY, Ho IC.
PLoS One 9(5):e96535. doi: 10.1371/journal.pone.0096535. eCollection 2014. 2014
7GATA3, ISL1
LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3.
Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, Zhang X, Evans SM, Cui Y, Cui S.
BMC Biol 12:25. doi: 10.1186/1741-7007-12-25. 2014
8GATA3
GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis.
Masse I, Barbollat-Boutrand L, Kharbili ME, Berthier-Vergnes O, Aubert D, Lamartine J.
Arch Dermatol Res 306(2):201-8. doi: 10.1007/s00403-013-1435-5. Epub 2013 Dec 18. 2014
9FOXA1, GATA3, KDM5B
Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes.
Zou MR, Cao J, Liu Z, Huh SJ, Polyak K, Yan Q.
J Biol Chem 289(25):17620-33. doi: 10.1074/jbc.M114.570853. Epub 2014 May 6. 2014
10GATA3, SPINK5
Regulation of serine protease inhibitor Kazal type-5 (SPINK5) gene expression in the keratinocytes.
Le NA, Katsuyama M, Demura M, Tanii H, Katsuyama H, Saijoh K.
Environ Health Prev Med 19(4):307-13. doi: 10.1007/s12199-014-0393-7. Epub 2014 Jun 4. 2014
11EBF1, GATA3
Transcriptional repression of Gata3 is essential for early B cell commitment.
Banerjee A, Northrup D, Boukarabila H, Jacobsen SE, Allman D.
Immunity 38(5):930-42. doi: 10.1016/j.immuni.2013.01.014. Epub 2013 May 16. 2013
12GATA3, YY1
Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
Hwang SS, Kim YU, Lee S, Jang SW, Kim MK, Koh BH, Lee W, Kim J, Souabni A, Busslinger M, Lee GR.
Proc Natl Acad Sci U S A 110(1):276-81. doi: 10.1073/pnas.1214682110. Epub 2012 Dec 17. 2013
13FGF10, GATA3
Gata3 directly regulates early inner ear expression of Fgf10.
Economou A, Datta P, Georgiadis V, Cadot S, Frenz D, Maconochie M.
Dev Biol 374(1):210-22. doi: 10.1016/j.ydbio.2012.11.028. Epub 2012 Dec 3. 2013
14GATA3, TCF3
E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.
Xu W, Carr T, Ramirez K, McGregor S, Sigvardsson M, Kee BL.
Blood 121(9):1534-42. doi: 10.1182/blood-2012-08-449447. Epub 2013 Jan 7. 2013
15DEL10PD, DGS2, GATA3, HDR
Clinical description of a patient carrying the smallest reported deletion involving 10p14 region.
Melis D, Genesio R, Boemio P, Del Giudice E, Cappuccio G, Mormile A, Ronga V, Conti A, Imperati F, Nitsch L, Andria G.
Am J Med Genet A 158A(4):832-5. doi: 10.1002/ajmg.a.34133. Epub 2012 Mar 9. 2012
16BRCA1, GATA3
BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers.
Tkocz D, Crawford NT, Buckley NE, Berry FB, Kennedy RD, Gorski JJ, Harkin DP, Mullan PB.
Oncogene 31(32):3667-78. doi: 10.1038/onc.2011.531. Epub 2011 Nov 28. 2012
17GATA3, HMMS, TRPS1
Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1.
Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B.
Nat Genet 44(6):709-13. doi: 10.1038/ng.2259. 2012
18CXCL12, GATA3, IRX5, TRPS1
Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1.
Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B.
Nat Genet 44(6):709-13. doi: 10.1038/ng.2259. 2012
19GATA3, HAND2
Cytokines inhibit norepinephrine transporter expression by decreasing Hand2.
Pellegrino MJ, Parrish DC, Zigmond RE, Habecker BA.
Mol Cell Neurosci 46(3):671-80. Epub 2011 Jan 15. 2011
20CASP14, GATA3
Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.
Asselin-Labat ML, Sutherland KD, Vaillant F, Gyorki DE, Wu D, Holroyd S, Breslin K, Ward T, Shi W, Bath ML, Deb S, Fox SB, Smyth GK, Lindeman GJ, Visvader JE.
Mol Cell Biol 31(22):4609-22. Epub 2011 Sep 19. 2011
21EOMES, GATA3
Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3.
Endo Y, Iwamura C, Kuwahara M, Suzuki A, Sugaya K, Tumes DJ, Tokoyoda K, Hosokawa H, Yamashita M, Nakayama T.
Immunity 35(5):733-45. 2011
22GATA3
GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.
Buza-Vidas N, Duarte S, Luc S, Bouriez-Jones T, Woll PS, Jacobsen SE.
Blood 118(5):1291-3. Epub 2011 Jun 13. 2011
23CDX2, GATA3, TEAD4
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2.
Ralston A, Cox BJ, Nishioka N, Sasaki H, Chea E, Rugg-Gunn P, Guo G, Robson P, Draper JS, Rossant J.
Development 137(3):395-403.PMID: 20081188 2010
24CTBP1, CTBP2, GATA1, GATA2, GATA3, ZFPM1, ZFPM2
GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis.
Jack BH, Crossley M.
J Biol Chem 285(42):32405-14. Epub 2010 Aug 11. 2010
25GATA3
Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells.
Stanelle J, Döring C, Hansmann ML, Küppers R.
Blood 116(20):4202-11. Epub 2010 Jul 26. 2010
26GATA3, PVT1, REL
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).
Enciso-Mora V, Broderick P, Ma Y, Jarrett RF, Hjalgrim H, Hemminki K, van den Berg A, Olver B, Lloyd A, Dobbins SE, Lightfoot T, van Leeuwen FE, Försti A, Diepstra A, Broeks A, Vijayakrishnan J, Shield L, Lake A, Montgomery D, Roman E, Engert A, von Strandmann EP, Reiners KS, Nolte IM, Smedby KE, Adami HO, Russell NS, Glimelius B, Hamilton-Dutoit S, de Bruin M, Ryder LP, Molin D, Sorensen KM, Chang ET, Taylor M, Cooke R, Hofstra R, Westers H, van Wezel T, van Eijk R, Ashworth A, Rostgaard K, Melbye M, Swerdlow AJ, Houlston RS.
Nat Genet 42(12):1126-30. Epub 2010 Oct 31. 2010
27GATA3, KLK1
Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3.
Son do N, Li L, Katsuyama H, Komatsu N, Saito M, Tanii H, Saijoh K.
Gene 436(1-2):121-7. Epub 2009 Feb 13. 2009
28GATA3, HDR
HDR syndrome: a novel "de novo" mutation in GATA3 gene.
Ferraris S, Del Monaco AG, Garelli E, Carando A, De Vito B, Pappi P, Lala R, Ponzone A.
Am J Med Genet A 149A(4):770-5. 2009
29GATA3, HDR
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome.
Gaynor KU, Grigorieva IV, Nesbit MA, Cranston T, Gomes T, Gortner L, Thakker RV.
J Clin Endocrinol Metab 94(10):3897-904. Epub 2009 Sep 1.PMID: 19723756 2009
30ELF1, GATA2, GATA3, GATA4, GATA6, TEK
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T.
J Biol Chem 284(42):29109-24. Epub 2009 Aug 12.PMID: 19674970 2009
31GATA3, TBX21
Cyclic regulation of T-Bet and GATA-3 in human endometrium.
Inman D, Kawana K, Schust D, Lininger R, Young S.
Reprod Sci 15(1):83-90.PMID: 18212358 2008
32GATA3, HDR
Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor.
Ali A, Christie PT, Grigorieva IV, Harding B, Van Esch H, Ahmed SF, Bitner-Glindzicz M, Blind E, Bloch C, Christin P, Clayton P, Gecz J, Gilbert-Dussardier B, Guillen-Navarro E, Hackett A, Halac I, Hendy GN, Lalloo F, Mache CJ, Mughal Z, Ong AC, Rinat C, Shaw N, Smithson SF, Tolmie J, Weill J, Nesbit MA, Thakker RV.
Hum Mol Genet 16(3):265-75. Epub 2007 Jan 8. 2007
33HDR, GATA3
Novel mutation in the gene encoding the GATA3 transcription factor in a Spanish familial case of hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome with female genital tract malformations.
Hernandez AM, Villamar M, Rosello L, Moreno-Pelayo MA, Moreno F, Del Castillo I.
Am J Med Genet A 143(7):757-62. No abstract available. 2007
34GATA3,GFI1B,TCF3
Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas.
Wei X, Kee BL.
Blood 109(10):4406-14. Epub 2007 Feb 1. 2007
35GATA3
Aberrant gata-3 expression in human pancreatic cancer.
Gulbinas A, Berberat PO, Dambrauskas Z, Giese T, Giese N, Autschbach F, Kleeff J, Meuer S, Buchler MW, Friess H.
J Histochem Cytochem 54(2):161-9. Epub 2005 Aug 8. 2006
36GATA3
Transcription factor GATA-3 is involved in repression of promoter activity of the human interleukin-4 gene.
Schwenger GT, Mordvinov VA, Sanderson CJ.
Biochemistry (Mosc) 70(9):1065-9. 2005
37STAT6, GATA3, KIF3A, IL4, IL13, RAD50
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.
Lee DU, Rao A.
Proc Natl Acad Sci U S A 101(45):16010-5. Epub 2004 Oct 26. 2004
38GATA3, HDR
Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome.
Nesbit MA, Bowl MR, Harding B, Ali A, Ayala A, Crowe C, Dobbie A, Hampson G, Holdaway I, Levine MA, McWilliams R, Rigden S, Sampson J, Williams AJ, Thakker RV.
J Biol Chem 279(21):22624-34. Epub 2004 Feb 24. 2004
39GATA3
Cutting edge: Identification of an alternative GATA-3 promoter directing tissue-specific gene expression in mouse and human.
Asnagli H, Afkarian M, Murphy KM.
J Immunol 168(9):4268-71. 2002
40GATA3
GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model.
Hofer T, Nathansen H, Lohning M, Radbruch A, Heinrich R.
Proc Natl Acad Sci U S A 99(14):9364-8. 2002
41GATA3, HDR
GATA3 abnormalities and the phenotypic spectrum of HDR syndrome.
Muroya K, Hasegawa T, Ito Y, Nagai T, Isotani H, Iwata Y, Yamamoto K, Fujimoto S, Seishu S, Fukushima Y, Hasegawa Y, Ogata T.
J Med Genet 38(6):374-80. 2001
42AIRE, GATA3, GCM2
Genetic developments in hypoparathyroidism.
Thakker RV.
Lancet 357(9261):974-6. No abstract available. 2001
43GATA3, HDR
GATA3 haplo-insufficiency causes human HDR syndrome.
Van Esch H, Groenen P, Nesbit MA, Schuffenhauer S, Lichtner P, Vanderlinden G, Harding B, Beetz R, Bilous RW, Holdaway I, Shaw NJ, Fryns JP, Van de Ven W, Thakker RV, Devriendt K.
Nature 406(6794):419-22. 2000
44GATA3
Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system.
Lim KC, Lakshmanan G, Crawford SE, Gu Y, Grosveld F, Engel JD.
Nat Genet 25(2):209-12. 2000
45GATA3
Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus.
Lakshmanan G, et al.
Mol Cell Biol 19(2):1558-68. 1999
46HDR, GATA3
Recurrent cerebral infarctions and del(10)(p14p15.1) de novo in HDR (hypoparathyroidism, sensorineural deafness, renal dysplasia) syndrome.
Fujimoto S, Yokochi K, Morikawa H, Nakano M, Shibata H, Togari H, Wada Y.
Am J Med Genet 86(5):427-9. 1999
47GATA2, GATA3
GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes.
Elefanty AG, et al.
EMBO J 15 : 319-333. 1996
48GATA3
Structure and expression of the human GATA3 gene.
Labastie MC, et al.
Genomics 21 : 1-6. 1994
49GATA3
A T-cell specific TCR delta DNA binding protein is a member of the human GATA family.
Joulin V, et al.
EMBO J 10 : 1809-1816. 1991
50GATA3, IL7R
93.
The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells.
Yagi R, Zhong C, Northrup DL, Yu F, Bouladoux N, Spencer S, Hu G, Barron L, Sharma S, Nakayama T, Belkaid Y, Zhao K, Zhu J agi R, Zhong C, Northrup DL, Yu F, Bouladoux N, Spencer S, Hu G, Barron L, Sharma S, Nakayama T, Belkaid Y, Zhao K, Zhu J.