| 1 | GAS6
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| Growth Arrest-Specific 6 Protein in Patients with Sjögren Syndrome: Determination of the Plasma Level and Expression in the Labial Salivary Gland.
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| Chen CH, Chen HC, Chang CC, Peng YJ, Lee CH, Shieh YS, Hung YJ, Lin YF.
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| PLoS One 10(10):e0139955. doi: 10.1371/journal.pone.0139955. eCollection 2015.
2015
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| 2 | GAS6
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| Gas6 delays senescence in vascular smooth muscle cells through the PI3K/ Akt/FoxO signaling pathway.
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| Jin CW, Wang H, Chen YQ, Tang MX, Fan GQ, Wang ZH, Li L, Zhang Y, Zhang W, Zhong M.
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| Cell Physiol Biochem 35(3):1151-66. doi: 10.1159/000373940. Epub 2015 Feb 6.
2015
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| 3 | AXL, GAS6
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| Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.
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| Kirane A, Ludwig KF, Sorrelle N, Haaland G, Sandal T, Ranaweera R, Toombs JE, Wang M, Dineen SP, Micklem D, Dellinger MT, Lorens JB, Brekken RA.
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| Cancer Res 75(18):3699-705. doi: 10.1158/0008-5472.CAN-14-2887-T. Epub 2015 Jul 23.
2015
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| 4 | FOXO1, GAS6, VCAM1
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| Growth arrest-specific 6 regulates thrombin-induced expression of vascular cell adhesion molecule-1 through forkhead box O1 in endothelial cells.
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| Bertin FR, Lemarié CA, Robins RS, Blostein MD.
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| J Thromb Haemost 13(12):2260-72. doi: 10.1111/jth.13156. Epub 2015 Nov 20.
2015
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| 5 | GAS6
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| Plasma levels of growth arrest specific protein 6 are increased in idiopathic recurrent pregnancy loss.
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| Eroglu M, Ozakpinar OB, Turkgeldi L, Sahin S, Herkiloglu D, Durukan B, Uras F.
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| Eur Rev Med Pharmacol Sci 18(10):1554-8.
2014
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| 6 | GAS6
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| Growth arrest-specific gene 6 protein promotes the proliferation and migration of endothelial progenitor cells through the PI3K/AKT signaling pathway.
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| Zuo PY, Chen XL, Lei YH, Liu CY, Liu YW.
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| Int J Mol Med 34(1):299-306. doi: 10.3892/ijmm.2014.1754. Epub 2014 Apr 24.
2014
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| 7 | GAS6
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| Gas6-induced tissue factor expression in endothelial cells is mediated through caveolin-1-enriched microdomains.
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| Laurance S, Aghourian MN, Jiva Lila Z, Lemarié CA, Blostein MD.
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| J Thromb Haemost 12(3):395-408. doi: 10.1111/jth.12481.
2014
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| 8 | GAS6
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| Elevated serum level of growth arrest-specific protein 6 (Gas6) in systemic lupus erythematosus patients is associated with nephritis and cutaneous vasculitis.
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| Wu CS, Hu CY, Tsai HF, Chyuan IT, Chan CJ, Chang SK, Hsu PN.
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| Rheumatol Int 34(5):625-9. doi: 10.1007/s00296-013-2882-1. Epub 2013 Nov 1.
2014
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| 9 | GAS6, THBD
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| Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification.
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| Son BK, Akishita M, Iijima K, Ogawa S, Arai T, Ishii H, Maemura K, Aburatani H, Eto M, Ouchi Y.
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| J Mol Cell Cardiol 56:72-80. doi: 10.1016/j.yjmcc.2012.12.013. Epub 2012 Dec 26.
2013
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| 10 | GAS6
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| Inhibitory role of Gas6 in intestinal tumorigenesis.
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| Akitake-Kawano R, Seno H, Nakatsuji M, Kimura Y, Nakanishi Y, Yoshioka T, Kanda K, Kawada M, Kawada K, Sakai Y, Chiba T.
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| Carcinogenesis 34(7):1567-74. doi: 10.1093/carcin/bgt069. Epub 2013 Feb 20.
2013
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| 11 | GAS6
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| Serum levels of growth arrest specific protein 6 are increased in preeclampsia.
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| Stepan H, Richter J, Kley K, Kralisch S, Jank A, Schaarschmidt W, Ebert T, Lössner U, Jessnitzer B, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M.
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| Regul Pept 182:7-11. doi: 10.1016/j.regpep.2012.12.013. Epub 2013 Jan 11.
2013
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| 12 | GAS6
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| Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques.
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| Clauser S, Meilhac O, Bièche I, Raynal P, Bruneval P, Michel JB, Borgel D.
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| Thromb Haemost 107(1):140-9. doi: 10.1160/TH11-05-0368. Epub 2011 Nov 10.
2012
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| 13 | AXL, GAS6, TYRO3
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| Activation of TYRO3/AXL tyrosine kinase receptors in thyroid cancer.
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| Avilla E, Guarino V, Visciano C, Liotti F, Svelto M, Krishnamoorthy G, Franco R, Melillo RM.
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| Cancer Res 71(5):1792-804. Epub 2011 Feb 22.
2011
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| 14 | GAS6
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| Elevated plasma gas6 levels are associated with venous thromboembolic disease.
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| Blostein MD, Rajotte I, Rao DP, Holcroft CA, Kahn SR.
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| J Thromb Thrombolysis 32(3):272-8. doi: 10.1007/s11239-011-0597-2.
2011
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| 15 | GAS6
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| Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination.
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| Binder MD, Xiao J, Kemper D, Ma GZ, Murray SS, Kilpatrick TJ.
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| PLoS One 6(3):e17727. doi: 10.1371/journal.pone.0017727.
2011
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| 16 | GAS6
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| GAS6 in systemic inflammatory diseases: with and without infection.
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| Hurtado B, de Frutos PG.
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| Crit Care 14(5):1003. doi: 10.1186/cc9263. Epub 2010 Oct 21.
2010
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| 17 | AXL, GAS6
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| Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood.
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| Ekman C, Stenhoff J, Dahlbäck B.
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| J Thromb Haemost 8(4):838-44. doi: 10.1111/j.1538-7836.2010.03752.x. Epub 2010 Jan 17.
2010
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| 18 | AXL, GAS6
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| The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
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| Park IK, Giovenzana C, Hughes TL, Yu J, Trotta R, Caligiuri MA.
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| Blood 113(11):2470-7. Epub 2008 Oct 7.
2009
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| 19 | AXL, GAS6
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| Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis.
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| Li Y, Ye X, Tan C, Hongo JA, Zha J, Liu J, Kallop D, Ludlam MJ, Pei L.
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| Oncogene 28(39):3442-55. Epub 2009 Jul 27.PMID: 1963368 2009
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| 20 | AXL, GAS6
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| Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
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| Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M.
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| J Immunol 183(5):3004-13. Epub 2009 Aug 5.PMID: 19657094 2009
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| 21 | GAS6
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| Plasma level of growth arrest-specific 6 (GAS6) protein and genetic variations in the GAS6 gene in patients with acute coronary syndrome.
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| Jiang L, Liu CY, Yang QF, Wang P, Zhang W.
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| Am J Clin Pathol 131(5):738-43.PMID: 19369636 2009
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| 22 | AXL, GAS6
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| Axl and growth arrest-specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme.
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| Hutterer M, Knyazev P, Abate A, Reschke M, Maier H, Stefanova N, Knyazeva T, Barbieri V, Reindl M, Muigg A, Kostron H, Stockhammer G, Ullrich A.
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| Clin Cancer Res 14(1):130-8.
2008
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| 23 | GAS6
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| GAS6 is an estrogen-inducible gene in mammary epithelial cells.
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| Mo R, Tony Zhu Y, Zhang Z, Rao SM, Zhu YJ.
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| Biochem Biophys Res Commun 353(1):189-94. Epub 2006 Dec 11. 2007
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| 24 | AXL, GAS6
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| Structural basis for Gas6-Axl signalling.
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| Sasaki T, Knyazev PG, Clout NJ, Cheburkin Y, Gohring W, Ullrich A, Timpl R, Hohenester E.
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| EMBO J 25(1):80-7. Epub 2005 Dec 15. 2006
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| 25 | AXL, GAS6, MERTK, TYRO3
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| Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
|
| Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA.
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| J Thromb Haemost 3(4):733-41. Epub 2005 Feb 23. 2005
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| 26 | GAS6
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| Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke.
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| Munoz X, Sumoy L, Ramirez-Lorca R, Villar J, de Frutos PG, Sala N.
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| Hum Mutat 23(5):506-12. 2004
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| 27 | AXL, GAS6
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| Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells.
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| Hasanbasic I, Cuerquis J, Varnum B, Blostein MD.
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| Am J Physiol Heart Circ Physiol 287(3):H1207-13. Epub 2004 May 6. 2004
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| 28 | AXL, GAS6
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| Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt.
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| Allen MP, et al.
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| Mol Endocrinol 13(2):191-201. 1999
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| 29 | GAS6
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| Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.
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| Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K.
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| J Biol Chem. 271(47):30022-7. 1996
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| 30 | GAS6
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| Assignment of the human GAS6 gene to chromosome 13q34 by fluorescence in situ hybridization.
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| Saccone S, et al.
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| Genomics 30 : 129-131. 1995
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| 31 | PROS1, AXL, TYRO3, GAS6
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| The anticoagulation factor protein S and its relative, Gas6, are ligandsfor the Tyro 3/Axl family of receptor tyrosine kinases.
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| Stitt TN, et al.
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| Cell 80 : 661-670. 1995
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| 32 | GAS6
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| The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.
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| Manfioletti G, et al.
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| Mol Cell Biol 13 : 4976-4985. 1993
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