| 1 | GAPDH, PRMT3
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| Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer.
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| Hsu MC, Tsai YL, Lin CH, Pan MR, Shan YS, Cheng TY, Cheng SH, Chen LT, Hung WC.
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| J Hematol Oncol. Jul 19;12(1):79. doi: 10.1186/s13045-019-0769-7. 2019
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| 2 | GAPDH, GAPDHS
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| Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme.
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| Danshina PV, Qu W, Temple BR, Rojas RJ, Miley MJ, Machius M, Betts L, O'Brien DA.
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| Mol Hum Reprod. Jun;22(6):410-26. doi: 10.1093/molehr/gaw016. Epub 2016 Feb 26 2016
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| 3 | GAPDH, SIAH1
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| High Glucose-induced Retinal Pericyte Apoptosis Depends on Association of GAPDH and Siah1.
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| Suarez S, McCollum GW, Jayagopal A, Penn JS.
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| J Biol Chem 290(47):28311-20. doi: 10.1074/jbc.M115.682385. Epub 2015 Oct 5.
2015
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| 4 | GAPDH, MAP3K5, SIAH1
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| Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade.
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| Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A.
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| J Biol Chem 290(1):56-64. doi: 10.1074/jbc.M114.596205. Epub 2014 Nov 12.
2015
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| 5 | GAPDH, MZF1
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| The glyceraldehyde 3-phosphate dehydrogenase gene (GAPDH) is regulated by myeloid zinc finger 1 (MZF-1) and is induced by calcitriol.
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| Piszczatowski RT, Rafferty BJ, Rozado A, Tobak S, Lents NH.
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| Biochem Biophys Res Commun 451(1):137-41. doi: 10.1016/j.bbrc.2014.07.082. Epub 2014 Jul 24.
2014
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| 6 | AIRE, GAPDH
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| AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.
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| Liiv I, Haljasorg U, Kisand K, Maslovskaja J, Laan M, Peterson P.
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| Biochem Biophys Res Commun 423(1):32-7. doi: 10.1016/j.bbrc.2012.05.057. Epub 2012 May 18.
2012
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| 7 | GAPDH, NPM1, RILPL1, SIAH1
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| S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1-GAPDH death cascade.
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| Lee SB, Kim CK, Lee KH, Ahn JY.
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| J Cell Biol 199(1):65-76. doi: 10.1083/jcb.201205015.
2012
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| 8 | GAPDH, SIAH1
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| siah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller cells.
|
| Yego EC, Mohr S.
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| J Biol Chem 285(5):3181-90. Epub 2009 Nov 23.PMID: 19940145 2010
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| 9 | GAPDH
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| Glyceraldehyde-3-phosphate dehydrogenase in retinal microvasculature: implications for the development and progression of diabetic retinopathy.
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| Madsen-Bouterse S, Mohammad G, Kowluru RA.
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| Invest Ophthalmol Vis Sci 51(3):1765-72. Epub 2009 Oct 29.
2010
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| 10 | GAPDH
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| Glyceraldehyde-3-phosphate dehydrogenase interacts with phosphorylated Akt resulting from increased blood glucose in rat cardiac muscle.
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| Baba T, Kobayashi H, Kawasaki H, Mineki R, Naito H, Ohmori D.
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| FEBS Lett 584(13):2796-800. Epub 2010 May 17.PMID: 20488185 2010
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| 11 | GAPDH
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| Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts.
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| Kwon HJ, Rhim JH, Jang IS, Kim GE, Park SC, Yeo EJ.
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| Exp Mol Med 42(4):254-69.PMID: 20177150 2010
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| 12 | GAPDH, ISYNA1
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| GAPDH regulates cellular heme insertion into inducible nitric oxide synthase.
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| Chakravarti R, Aulak KS, Fox PL, Stuehr DJ.
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| Proc Natl Acad Sci U S A 107(42):18004-9. Epub 2010 Oct 4. 2010
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| 13 | GAPDH
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| GAPDH mediates nitrosylation of nuclear proteins.
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| Kornberg MD, Sen N, Hara MR, Juluri KR, Nguyen JV, Snowman AM, Law L, Hester LD, Snyder SH.
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| Nat Cell Biol. 12(11):1094-100. 2010
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| 14 | GAPDH
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| Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death.
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| Nakajima H, Amano W, Kubo T, Fukuhara A, Ihara H, Azuma YT, Tajima H, Inui T, Sawa A, Takeuchi T.
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| J Biol Chem 284(49):34331-41. Epub 2009 Oct 16.PMID: 19837666 2009
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| 15 | GAPDH
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| Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions.
|
| Hwang NR, Yim SH, Kim YM, Jeong J, Song EJ, Lee Y, Lee JH, Choi S, Lee KJ.
|
| Biochem J 423(2):253-64.PMID: 19650766 2009
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| 16 | GAPDH
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| Extracellular GAPDH binds to L1 and enhances neurite outgrowth.
|
| Makhina T, Loers G, Schulze C, Ueberle B, Schachner M, Kleene R.
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| Mol Cell Neurosci 41(2):206-18. Epub 2009 Mar 11.PMID: 19285135 2009
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| 17 | FKBP6, GAPDH, HSP90AA1, SYCP1
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| FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor.
|
| Jarczowski F, Jahreis G, Erdmann F, Schierhorn A, Fischer G, Edlich F.
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| J Biol Chem 284(2):766-73. Epub 2008 Nov 10.PMID: 19001379 2009
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| 18 | GAPDH, RILPL1
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| GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation.
|
| Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Hester L, Doré S, Snyder SH, Sawa A.
|
| Neuron 63(1):81-91. Erratum in: Neuron. 2009 Sep 10;63(5):709. Aggrawal, Nishant [corrected to Agrawal, Nishant].
2009
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| 19 | GAPDH
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| Glycolytic enzyme GAPDH promotes peroxide stress signaling through multistep phosphorelay to a MAPK cascade.
|
| Morigasaki S, Shimada K, Ikner A, Yanagida M, Shiozaki K.
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| Mol Cell 30(1):108-13.PMID: 18406331 2008
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| 20 | GAPDH
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| GAPDH is not regulated in human glioblastoma under hypoxic conditions.
|
| Said HM, Hagemann C, Stojic J, Schoemig B, Vince GH, Flentje M, Roosen K, Vordermark D.
|
| BMC Mol Biol 8:55. 2007
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| 21 | GAPDH
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| The macrophage cell surface glyceraldehyde-3-phosphate dehydrogenase is a novel transferrin receptor.
|
| Raje CI, Kumar S, Harle A, Nanda JS, Raje M.
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| J Biol Chem 282(5):3252-61. Epub 2006 Nov 22. 2007
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| 22 | GAPDH
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| GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.
|
| Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, Larochette N, Zamzami N, Jan G, Kroemer G, Brenner C.
|
| Oncogene 26(18):2606-20. Epub 2006 Oct 30.
2007
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| 23 | GAPDH, TPPP
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| Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies.
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| Oláh J, Tokési N, Vincze O, Horváth I, Lehotzky A, Erdei A, Szájli E, Medzihradszky KF, Orosz F, Kovács GG, Ovádi J.
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| FEBS Lett 580(25):5807-14. Epub 2006 Sep 27. 2006
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| 24 | GAPDH
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| Glyceraldehyde 3-phosphate dehydrogenase is a SET-binding protein and regulates cyclin B-cdk1 activity.
|
| Carujo S, Estanyol JM, Ejarque A, Agell N, Bachs O, Pujol MJ.
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| Oncogene. 25(29):4033-42. 2006
|
| 25 | GAPDH
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| Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease.
|
| Cumming RC, Schubert D.
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| FASEB J 19(14):2060-2. Epub 2005 Sep 26. 2005
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| 26 | GAPDH
|
| Identification of glyceraldehyde-3-phosphate dehydrogenase of epithelial cells as a second molecule that binds to Porphyromonas gingivalis fimbriae.
|
| Sojar HT, Genco RJ.
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| FEMS Immunol Med Microbiol 45(1):25-30. Epub 2005 Feb 5. 2005
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| 27 | GAPDH
|
| Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal.
|
| Tsuchiya Y, Yamaguchi M, Chikuma T, Hojo H.
|
| Arch Biochem Biophys 438(2):217-22. 2005
|
| 28 | GAPDH
|
| Aging of human glyceraldehyde-3-phosphate dehydrogenase is dependent on its subcellular localization.
|
| Mazzola JL, Sirover MA.
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| Biochim Biophys Acta 1722(2):168-74. Epub 2005 Jan 5. 2005
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| 29 | GAPDH
|
| Pro-apoptotic protein glyceraldehyde-3-phosphate dehydrogenase promotes the formation of Lewy body-like inclusions.
|
| Tsuchiya K, Tajima H, Kuwae T, Takeshima T, Nakano T, Tanaka M, Sunaga K, Fukuhara Y, Nakashima K, Ohama E, Mochizuki H, Mizuno Y, Katsube N, Ishitani R.
|
| Eur J Neurosci 21(2):317-26. 2005
|
| 30 | CAMK1, GAPDH, PPM1E
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| Identification of major Ca(2+)/calmodulin-dependent protein kinase phosphatase-binding proteins in brain: biochemical analysis of the interaction.
|
| Ishida A, Tada Y, Nimura T, Sueyoshi N, Katoh T, Takeuchi M, Fujisawa H, Taniguchi T, Kameshita I.
|
| Arch Biochem Biophys 435(1):134-46. 2005
|
| 31 | UBE2K, PACSIN1, ZDHHC17, TAF4, TRIP10, DLG4, SH3GL3, TCERG1, CTBP1, GAPDH
|
| Huntingtin-protein interactions and the pathogenesis of Huntington's disease.
|
| Li SH, Li XJ.
|
| Trends Genet 20(3):146-54. Review. 2004
|
| 32 | GAPDH
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| Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
|
| Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, Cravchik A, Ross D, Lau K, Kwok S, Chang SY, Catanese J, Sninsky J, White TJ, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Owen M, Williams J, Goate A, Grupe A.
|
| Proc Natl Acad Sci U S A 101(44):15688-93. Epub 2004 Oct 26. 2004
|
| 33 | GAPDH
|
| Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity.
|
| Tisdale EJ, Kelly C, Artalejo CR.
|
| J Biol Chem 279(52):54046-52. Epub 2004 Oct 14. 2004
|
| 34 | GAPDH
|
| Thioredoxin, a regulator of gene expression.
|
| Kontou M, Will RD, Adelfalk C, Wittig R, Poustka A, Hirsch-Kauffmann M, Schweiger M.
|
| Oncogene 23(12):2146-52. 2004
|
| 35 | GAPDH
|
| Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase.
|
| Sundararaj KP, Wood RE, Ponnusamy S, Salas AM, Szulc Z, Bielawska A, Obeid LM, Hannun YA, Ogretmen B.
|
| J Biol Chem 279(7):6152-62. Epub 2003 Nov 20. 2004
|
| 36 | GAPDH
|
| The muscle-specific calmodulin-dependent protein kinase assembles with the glycolytic enzyme complex at the sarcoplasmic reticulum and modulates the activity of glyceraldehyde-3-phosphate dehydrogenase in a Ca2+/calmodulin-dependent manner.
|
| Singh P, Salih M, Leddy JJ, Tuana BS.
|
| J Biol Chem. 279(34):35176-82. 2004
|
| 37 | GAPDH
|
| Interactions among p22, glyceraldehyde-3-phosphate dehydrogenase and microtubules.
|
| Andrade J, Pearce ST, Zhao H, Barroso M.
|
| Biochem J. 384(Pt 2):327-36. 2004
|
| 38 | BCL6, HSP90AA2, GAPDH
|
| Molecular characterization of BCL6 breakpoints in primary diffuse large B-cell lymphomas of the central nervous system identifies GAPD as novel translocation partner.
|
| Montesinos-Rongen M, Akasaka T, Zuhlke-Jenisch R, Schaller C, Van Roost D, Wiestler OD, Siebert R, Deckert M.
|
| Brain Pathol 13(4):534-8. 2003
|
| 39 | GAPDH
|
| Amino acid control of the human glyceraldehyde 3-phosphate dehydrogenase gene transcription in hepatocyte.
|
| Claeyssens S, Gangneux C, Brasse-Lagnel C, Ruminy P, Aki T, Lavoinne A, Salier JP.
|
| Am J Physiol Gastrointest Liver Physiol 285(5):G840-9. Epub 2003 Jul 3. 2003
|
| 40 | GAPDH
|
| Hydrogen peroxide induces association between glyceraldehyde 3-phosphate dehydrogenase and phospholipase D2 to facilitate phospholipase D2 activation in PC12 cells.
|
| Kim JH, Lee S, Park JB, Lee SD, Kim JH, Ha SH, Hasumi K, Endo A, Suh PG, Ryu SH.
|
| J Neurochem 85(5):1228-36. 2003
|
| 41 | GAPDH
|
| HIF-2alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells.
|
| Graven KK, Bellur D, Klahn BD, Lowrey SL, Amberger E.
|
| Biochim Biophys Acta 1626(1-3):10-8. 2003
|
| 42 | GAPDH
|
| Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts.
|
| Mazzola JL, Sirover MA.
|
| J Neurosci Res 71(2):279-85. 2003
|
| 43 | GAPDH
|
| Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter.
|
| Lu S, Gu X, Hoestje S, Epner DE.
|
| Biochim Biophys Acta 1574(2):152-6. 2002
|
| 44 | GAPDH
|
| Alteration of nuclear glyceraldehyde-3-phosphate dehydrogenase structure in Huntington's disease fibroblasts.
|
| Mazzola JL, Sirover MA.
|
| Brain Res Mol Brain Res 100(1-2):95-101. 2002
|
| 45 | GAPDH
|
| Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?
|
| Mazzola JL, Sirover MA.
|
| Neurotoxicology 23(4-5):603-9. Review. 2002
|
| 46 | GAPDH
|
| Glyceraldehyde-3-phosphate dehydrogenase associates with actin filaments in serum deprived NIH 3T3 cells only.
|
| Schmitz HD, Bereiter-Hahn J.
|
| Cell Biol Int. 26(2):155-64. 2002
|
| 47 | GAPDH
|
| Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway.
|
| Tisdale EJ.
|
| J Biol Chem. 277(5):3334-41. 2002
|
| 48 | GAPDH
|
| Thermodynamics of the folding of D-glyceraldehyde-3-phosphate dehydrogenase assisted by protein disulfide isomerase studied by microcalorimetry.
|
| Liang Y, Li J, Chen J, Wang CC.
|
| Eur J Biochem. 268(15):4183-9. 2001
|
| 49 | GAPDH
|
| Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer.
|
| Revillion F, Pawlowski V, Hornez L, Peyrat JP.
|
| Eur J Cancer 36(8):1038-42. 2000
|
| 50 | GAPDH
|
| Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction.
|
| Vila MR, Nicolas A, Morote J, de I, Meseguer A.
|
| Cancer 89(1):152-64. 2000
|
| 51 | GAPDH, HAP1, HTT, HIP1, UBE2K
|
| Recent advances on the pathogenesis of Huntington's disease.
|
| Petersen A, Mani K, Brundin P.
|
| Exp Neurol 157(1):1-18. Review. 1999
|
| 52 | GAPDH
|
| A study on the complexes between human erythrocyte enzymes participating in the conversions of 1,3-diphosphoglycerate.
|
| Fokina KV, Dainyak MB, Nagradova NK, Muronetz VI.
|
| Arch Biochem Biophys. 345(2):185-92. 1997
|
| 53 | GAPDH
|
| Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase.
|
| Koshy B, Matilla T, Burright EN, Merry DE, Fischbeck KH, Orr HT, Zoghbi HY.
|
| Hum Mol Genet. 5(9):1311-8. 1996
|
| 54 | GAPDH
|
| Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.
|
| Burke JR, Enghild JJ, Martin ME, Jou YS, Myers RM, Roses AD, Vance JM, Strittmatter WJ.
|
| Nat Med. 2(3):347-50. 1996
|
| 55 | APP, GAPDH
|
| Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein.
|
| Schulze H, Schuler A, Stüber D, Döbeli H, Langen H, Huber G.
|
| J Neurochem. 60(5):1915-22. 1993
|
| 56 | CRISP2, GAPDH, GAPDHL1, GAPDHL10, GAPDHL11, GAPDHL12, GAPDHL13, GAPDHL14, GAPDHL15, GAPDHL16, GAPDHL18, GAPDHL19, GAPDHL3, GAPDHL4, GAPDHL5, GAPDHL6, GAPDHL7, GAPDHL8, GAPDHL9, GAPDHP1, GAPDHP14, GAPDHP16, GAPDHP2
|
| Members of the human glyceraldehyde-3-phosphate dehydrogenase-related gene family map to dispersed chromosomal locations.
|
| Benham FJ, et al.
|
| Genomics 5 : 209-214. 1989
|
| 57 | GAPDH
|
| Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers.
|
| Tokunaga K, Nakamura Y, Sakata K, Fujimori K, Ohkubo M, Sawada K, Sakiyama S.
|
| Cancer Res 47(21):5616-9. 1987
|
| 58 | ENO2, GAPDH, CS
|
| Chromosomal assignment and regional localization of CS, ENO2, GAPDH, LDHb, PEPB, and TPI in man-rodent cell hybrids.
|
| Herbschleb-Voogt E, et al.
|
| Cytogenet Cell Genet 22 : 482-486. 1978
|
| 59 | GAPDH
|
| Human glyceraldehyde-3-phosphate dehydrogenase in man-rodent somatic cell hybrids.
|
| Bruns GAP, et al.
|
| Science 192 : 54-56. 1976
|