Citations for
1GADD45A, GADD45B, GADD45G, MAP2K7
GADD45 family proteins suppress JNK signaling by targeting MKK7.
Ueda T, Kohama Y, Kuge A, Kido E, Sakurai H.
Arch Biochem Biophys 635:1-7. doi: 10.1016/j.abb.2017.10.005. Epub 2017 Oct 14. 2017
2GADD45G, MAP2K7
Genetic variants of JNK and p38α pathways and risk of non-small cell lung cancer in an Eastern Chinese population.
Jia M, Zhu M, Zhou F, Wang M, Sun M, Yang Y, Wang X, Wang J, Jin L, Xiang J, Zhang Y, Chang J, Wei Q.
Int J Cancer 140(4):807-817. doi: 10.1002/ijc.30508. Epub 2016 Nov 16. 2017
3GADD45G, PAX5
Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β-catenin signalling and GADD45G expression.
Zhao L, Li S, Gan L, Li C, Qiu Z, Feng Y, Li J, Li L, Li C, Peng W, Xu C, Wang Z, Hui T, Ren G, Tao Q, Xiang T.
J Cell Mol Med 20(5):842-54. doi: 10.1111/jcmm.12768. Epub 2016 Feb 4. 2016
4CDK11A, GADD45A, GADD45G, SPDEF
GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration.
Tamura RE, Paccez JD, Duncan KC, Morale MG, Simabuco FM, Dillon S, Correa RG, Gu X, Libermann TA, Zerbini LF.
Oncotarget 7(12):13865-79. doi: 10.18632/oncotarget.7355. 2016
5GADD45G, ZEB2
SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells.
Xu G, Zhang L, Ma A, Qian Y, Ding Q, Liu Y, Wang B, Yang Z, Liu Y.
Oncotarget 6(32):33636-47. doi: 10.18632/oncotarget.5602. 2015
6GADD45G
Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma.
Ou DL, Shyue SK, Lin LI, Feng ZR, Liou JY, Fan HH, Lee BS, Hsu C, Cheng AL.
Oncotarget 6(29):27953-65. doi: 10.18632/oncotarget.4446. 2015
7GADD45G
GADD45γ regulates the thermogenic capacity of brown adipose tissue.
Gantner ML, Hazen BC, Conkright J, Kralli A.
Proc Natl Acad Sci U S A 111(32):11870-5. doi: 10.1073/pnas.1406638111. Epub 2014 Jul 28. 2014
8GADD45G
Growth arrest and DNA damage 45G down-regulation contributes to Janus kinase/signal transducer and activator of transcription 3 activation and cellular senescence evasion in hepatocellular carcinoma.
Zhang L, Yang Z, Ma A, Qu Y, Xia S, Xu D, Ge C, Qiu B, Xia Q, Li J, Liu Y.
Hepatology 59(1):178-89. doi: 10.1002/hep.26628. Epub 2013 Nov 18. 2014
9GADD45G
Gadd45g is essential for primary sex determination, male fertility and testis development.
Johnen H, González-Silva L, Carramolino L, Flores JM, Torres M, Salvador JM.
PLoS One 8(3):e58751. doi: 10.1371/journal.pone.0058751. Epub 2013 Mar 13. 2013
10GADD45G
GADD45G functions in male sex determination by promoting p38 signaling and Sry expression.
Gierl MS, Gruhn WH, von Seggern A, Maltry N, Niehrs C.
Dev Cell 23(5):1032-42. doi: 10.1016/j.devcel.2012.09.014. Epub 2012 Oct 25. 2012
11GADD45G
Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas.
Mezzomo LC, Gonzales PH, Pesce FG, Kretzmann Filho N, Ferreira NP, Oliveira MC, Kohek MB.
Pituitary 15(3):420-7. doi: 10.1007/s11102-011-0340-1. 2012
12GADD45G, MAP3K4
Gadd45γ and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression.
Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A.
Dev Cell 23(5):1020-31. doi: 10.1016/j.devcel.2012.09.016. Epub 2012 Oct 25. 2012
13ASCL1, GADD45G
Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation.
Huang HS, Kubish GM, Redmond TM, Turner DL, Thompson RC, Murphy GG, Uhler MD.
Mol Cell Neurosci 44(3):282-96. doi: 10.1016/j.mcn.2010.03.014. Epub 2010 Apr 9. 2010
14BRCA1, GADD45A, GADD45B, GADD45G, NFYA, POU2F1
BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.
Fan W, Jin S, Tong T, Zhao H, Fan F, Antinore MJ, Rajasekaran B, Wu M, Zhan Q.
J Biol Chem 277(10):8061-7. 2002
15GADD45G
Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis.
Zhang X, Sun H, Danila DC, Johnson SR, Zhou Y, Swearingen B, Klibanski A.
J Clin Endocrinol Metab 87(3):1262-7. 2002
16GADD45G
Assignment of human GADD45G to chromosome 9q22.1-->q22.3 by radiation hybrid mapping.
Gong R, Yu L, Zhang H, Tu Q, Zhao Y, Yang J, Xu Y, Zhao S.
Cytogenet Cell Genet 88(1-2):95-6. 2000
17GADD45G
CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control.
Zhang W, Bae I, Krishnaraju K, Azam N, Fan W, Smith K, Hoffman B, Liebermann DA.
Oncogene 18(35):4899-907 1999
18GADD45G
Molecular cloning, expression, and mapping of a novel human cDNA, GRP17, highly homologous to human gadd45 and murine MyD118.
Suzuki M, Watanabe TK, Fujiwara T, Nakamura Yp6, Takahashi E, Tanigami A.
J Hum Genet 44(5):300-3. 1999