Citations for
1G6PD, SLC2A1
Heat shock induces the cellular antioxidant defenses peroxiredoxin, glutathione and glucose 6-phosphate dehydrogenase through Nrf2.
Tchouagué M, Grondin M, Glory A, Averill-Bates D.
Chem Biol Interact 310:108717. doi: 10.1016/j.cbi.2019.06.030. Epub 2019 Jun 21. 2019
2G6PD
Glucose-6-phosphate dehydrogenase (G6PD) activity can modulate macrophage response to Leishmania major infection.
Zamani S, Hoseini AZ, Namin AM.
Int Immunopharmacol 69:178-183. doi: 10.1016/j.intimp.2019.01.028. Epub 2019 Feb 1. 2019
3G6PD
Prognostic significance of G6PD expression and localization in lung adenocarcinoma.
Nagashio R, Oikawa S, Yanagita K, Hagiuda D, Kuchitsu Y, Igawa S, Naoki K, Satoh Y, Ichinoe M, Murakumo Y, Saegusa M, Sato Y.
Biochim Biophys Acta Proteins Proteom 1867(1):38-46. doi: 10.1016/j.bbapap.2018.05.005. Epub 2018 May 9. 2019
4G6PD
Modulation of G6PD affects bladder cancer via ROS accumulation and the AKT pathway in vitro.
Chen X, Xu Z, Zhu Z, Chen A, Fu G, Wang Y, Pan H, Jin B.
Int J Oncol 53(4):1703-1712. doi: 10.3892/ijo.2018.4501. Epub 2018 Jul 25. 2018
5G6PD, G6PDD
Hepatic transcriptional profiling response to fava bean-induced oxidative stress in glucose-6-phosphate dehydrogenase-deficient mice.
Du G, Xiao M, Wei X, Zhou C, Li S, Cai W.
Gene 652:66-77. doi: 10.1016/j.gene.2018.02.014. Epub 2018 Feb 8. 2018
6G6PD, TALDO1
Silencing of the pentose phosphate pathway genes influences DNA replication in human fibroblasts.
Fornalewicz K, Wieczorek A, Węgrzyn G, Łyżeń R.
Gene 635:33-38. doi: 10.1016/j.gene.2017.09.005. Epub 2017 Sep 5. 2017
7G6PD
G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway.
Cao L, Zhang D, Chen J, Qin YY, Sheng R, Feng X, Chen Z, Ding Y, Li M, Qin ZH.
Free Radic Biol Med 112:433-444. doi: 10.1016/j.freeradbiomed.2017.08.011. Epub 2017 Aug 18. 2017
8G6PD, PAK4
PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth.
Zhang X, Zhang X, Li Y, Shao Y, Xiao J, Zhu G, Li F.
Cell Death Dis 8(5):e2820. doi: 10.1038/cddis.2017.85. 2017
9G6PD, G6PDD
Coupling between Protein Stability and Catalytic Activity Determines Pathogenicity of G6PD Variants.
Cunningham AD, Colavin A, Huang KC, Mochly-Rosen D.
Cell Rep 18(11):2592-2599. doi: 10.1016/j.celrep.2017.02.048. 2017
10G6PD, IDH2, SIRT5
SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense.
Zhou L, Wang F, Sun R, Chen X, Zhang M, Xu Q, Wang Y, Wang S, Xiong Y, Guan KL, Yang P, Yu H, Ye D.
EMBO Rep 17(6):811-22. doi: 10.15252/embr.201541643. Epub 2016 Apr 9. 2016
11G6PD, G6PDD
Glucose-6-Phosphate Dehydrogenase: Update and Analysis of New Mutations around the World.
Gómez-Manzo S, Marcial-Quino J, Vanoye-Carlo A, Serrano-Posada H, Ortega-Cuellar D, González-Valdez A, Castillo-Rodríguez RA, Hernández-Ochoa B, Sierra-Palacios E, Rodríguez-Bustamante E, Arreguin-Espinosa R.
Int J Mol Sci 17(12). pii: E2069. Review. 2016
12G6PD, SIRT2
SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation.
Xu SN, Wang TS, Li X, Wang YP.
Sci Rep 6:32734. doi: 10.1038/srep32734. 2016
13G6PD
Age-dependent detection of erythrocytes glucose-6-phosphate dehydrogenase and its correlation with oxidative stress.
Maurya PK, Kumar P, Chandra P.
Arch Physiol Biochem 122(2):61-6. doi: 10.3109/13813455.2015.1136648. Epub 2016 Jan 27. 2016
14G6PD, G6PDD
The stability of G6PD is affected by mutations with different clinical phenotypes.
Gómez-Manzo S, Terrón-Hernández J, De la Mora-De la Mora I, González-Valdez A, Marcial-Quino J, García-Torres I, Vanoye-Carlo A, López-Velázquez G, Hernández-Alcántara G, Oria-Hernández J, Reyes-Vivas H, Enríquez-Flores S.
Int J Mol Sci 15(11):21179-201. doi: 10.3390/ijms151121179. 2014
15G6PD, G6PDD
DNA hypermethylation and X chromosome inactivation are major determinants of phenotypic variation in women heterozygous for G6PD mutations.
Wang J, Xiao QZ, Chen YM, Yi S, Liu D, Liu YH, Zhang CM, Wei XF, Zhou YQ, Zhong XM, Zhao CY, Xiong F, Wei XC, Xu XM.
Blood Cells Mol Dis 53(4):241-5. doi: 10.1016/j.bcmd.2014.06.001. Epub 2014 Jun 21. 2014
16G6PD, G6PDD
DNA hypermethylation and X chromosome inactivation are major determinants of phenotypic variation in women heterozygous for G6PD mutations.
Wang J, Xiao QZ, Chen YM, Yi S, Liu D, Liu YH, Zhang CM, Wei XF, Zhou YQ, Zhong XM, Zhao CY, Xiong F, Wei XC, Xu XM.
Blood Cells Mol Dis 53(4):241-5. doi: 10.1016/j.bcmd.2014.06.001. Epub 2014 Jun 21. 2014
17G6PD, G6PDD
Transcriptional and epigenetic basis for restoration of G6PD enzymatic activity in human G6PD-deficient cells.
Makarona K, Caputo VS, Costa JR, Liu B, O'Connor D, Iskander D, Roper D, Robertson L, Bhatnagar N, Terpos E, Georgiou E, Papaioannou M, Layton DM, Luzzatto L, Roberts I, Karadimitris A.
Blood 124(1):134-41. doi: 10.1182/blood-2014-02-553792. Epub 2014 May 7. 2014
18G6PD
Cloning, expression, purification and characterization of his-tagged human glucose-6-phosphate dehydrogenase: a simplified method for protein yield.
Gómez-Manzo S, Terrón-Hernández J, de la Mora-de la Mora I, García-Torres I, López-Velázquez G, Reyes-Vivas H, Oria-Hernández J.
Protein J 32(7):585-92. doi: 10.1007/s10930-013-9518-x. 2013
19G6PD, SRSF3, SRSF4
Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver.
Walsh CM, Suchanek AL, Cyphert TJ, Kohan AB, Szeszel-Fedorowicz W, Salati LM.
J Biol Chem 288(4):2816-28. doi: 10.1074/jbc.M112.410803. Epub 2012 Dec 11. 2013
20G6PD
Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose.
Zhang Z, Yang Z, Zhu B, Hu J, Liew CW, Zhang Y, Leopold JA, Handy DE, Loscalzo J, Stanton RC.
PLoS One 7(11):e49128. doi: 10.1371/journal.pone.0049128. Epub 2012 Nov 19. 2012
21G6PD
Glucose-6-phosphate dehydrogenase, NADPH, and cell survival.
Stanton RC.
IUBMB Life 64(5):362-9. doi: 10.1002/iub.1017. Epub 2012 Mar 20. Review. 2012
22G6PD, G6PDD
Association of homozygous sickle cell anemia and glucose-6-phosphate dehydrogenase deficiency.
Lesesve JF, Perrin J.
Eur J Haematol 88(4):370. doi: 10.1111/j.1600-0609.2011.01737.x. Epub 2012 Jan 4. No abstract available. 2012
23G6PD
G6PD up-regulation promotes pancreatic beta-cell dysfunction.
Lee JW, Choi AH, Ham M, Kim JW, Choe SS, Park J, Lee GY, Yoon KH, Kim JB.
Endocrinology 152(3):793-803. doi: 10.1210/en.2010-0606. Epub 2011 Jan 19. 2011
24G6PD, G6PDD
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia.
Nouraie M, Reading NS, Campbell A, Minniti CP, Rana SR, Luchtman-Jones L, Kato GJ, Gladwin MT, Castro OL, Prchal JT, Gordeuk VR.
Br J Haematol 150(2):218-25. doi: 10.1111/j.1365-2141.2010.08215.x. Epub 2010 May 9. 2010
25G6PD
High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis.
Zhang Z, Liew CW, Handy DE, Zhang Y, Leopold JA, Hu J, Guo L, Kulkarni RN, Loscalzo J, Stanton RC.
FASEB J 24(5):1497-505. doi: 10.1096/fj.09-136572. Epub 2009 Dec 23. 2010
26CYB5R3, G6PD
Effects of aging on antioxidant response and phagocytosis in senescent erythrocytes.
Brajovich ML, Rucci A, Acosta IL, Cotorruelo C, García Borrás S, Racca L, Biondi C, Racca A.
Immunol Invest 38(6):551-9. 2009
27G6PD
Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells.
Pan S, World CJ, Kovacs CJ, Berk BC.
Arterioscler Thromb Vasc Biol 29(6):895-901. doi: 10.1161/ATVBAHA.109.184812. Epub 2009 Apr 9. 2009
28G6PD
Telomerase prevents accelerated senescence in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts.
Wu YH, Cheng ML, Ho HY, Chiu DT, Wang TC.
J Biomed Sci 16:18. doi: 10.1186/1423-0127-16-18. 2009
29G6PD
What is the role of the second "structural" NADP+-binding site in human glucose 6-phosphate dehydrogenase?
Wang XT, Chan TF, Lam VM, Engel PC.
Protein Sci 17(8):1403-11. doi: 10.1110/ps.035352.108. Epub 2008 May 20. 2008
30G6PD
Structure and function of glucose-6-phosphate dehydrogenase-deficient variants in Chinese population.
Jiang W, Yu G, Liu P, Geng Q, Chen L, Lin Q, Ren X, Ye W, He Y, Guo Y, Duan S, Wen J, Li H, Qi Y, Jiang C, Zheng Y, Liu C, Si E, Zhang Q, Tian Q, Du C.
Hum Genet 119(5):463-78. Epub 2006 Apr 11. 2006
31G6PD
cAMP response element binding protein (CREB) activates transcription via two distinct genetic elements of the human glucose-6-phosphatase gene.
Thiel G, Al Sarraj J, Stefano L.
BMC Mol Biol 6:2. 2005
32G6PD
G6PD is indispensable for erythropoiesis after the embryonic-adult hemoglobin switch.
Paglialunga F, Fico A, Iaccarino I, Notaro R, Luzzatto L, Martini G, Filosa S.
Blood 104(10):3148-52. Epub 2004 Jul 22. 2004
33G6PD, G6PDD
Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance.
Tishkoff SA, Varkonyi R, Cahinhinan N, Abbes S, Argyropoulos G, Destro-Bisol G, Drousiotou A, Dangerfield B, Lefranc G, Loiselet J, Piro A, Stoneking M, Tagarelli A, Tagarelli G, Touma EH, Williams SM, Clark AG.
Science 293(5529):455-62. 2001
34DNMT3B, G6PD, ICF, VAMP7
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant.
Hansen RS, Stoger R, Wijmenga C, Stanek AM, Canfield TK, Luo P, Matarazzo MR, D'Esposito M, Feil R, Gimelli G, Weemaes CM, Laird CD, Gartler SM.
Hum Mol Genet 9(18):2575-87. 2000
35G6PD, G6PDD, GBTS, UGT1A1
Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia.
Kaplan M, Renbaum P, Levy-Lahad E, Hammerman C, Lahad A, Beutler E.
Proc Natl Acad Sci U S A 94(22):12128-32. 1997
36CVG@, FLNA, G6PD, GDI1, PLXNA3, RGCP@
Long-range sequence analysis in Xq28 : thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.
Chen EY, et al.
Hum Mol Genet 5 : 659-668. 1996
37G6PD, G6PDD
Independent origin of single and double mutations in the human glucose 6-phosphate dehydrogenase gene.
Vulliamy T, et al.
Hum Mutat 8 : 311-318. 1996
38G6PD, G6PDD
Molecular genetics of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Spain : identification of two new point mutations in the G6PD gene.
Rovira A, et al.
Br J Haematol 91 : 66-71. 1995
39G6PD, RGCP@
Sequence analysis of 220kb of high GC DNA between the RCP/GCP and G6PD loci in human Xq28. (abstract).
d'Urso M, et al.
Cytogenet Cell Genet 71 : 342. 1995
40G6PD, FAM3A
Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28.
Zollo M, et al.
DNA Seq 6 : 1-11. 1995
41G6PD, G6PDD
Identification of mutations in the gene for glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A.
Lei KJ, et al.
J Clin Invest 93 : 1994-1999. 1994
42ATP6AP1, DNASE1L1, DXS253E, DXS254E, EMD, FLNA, G6PD, GDI1, RGCP@, RPL10, UBL4A
Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.
Bione S, et al.
Proc Natl Acad Sci U S A 90 : 10977-10981. 1993
43G6PD, G6PDD
Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency in patients of Chinese descent and identification of new base substitutions in the human G6PD gene.
Chiu DTY, et al.
Blood 81 : 2150-2154. 1993
44G6PD, G6PDD
Molecular abnormality of G6PD Konan and G6PD Ube, the most common glucose-6-phosphate dehydrogenase variants in Japan.
Hirono A, et al.
Hum Genet 91 : 507-508. 1993
45G6PD, G6PDD
G6PD haplotypes spanning Xq28 from F8C to red/green color vision.
Filosa S, et al.
Genomics 17 : 6-14. 1993
46G6PD, G6PDD
Variants of glucose-6-phosphate dehydrogenase are due to missense mutations spread throughout the coding region of the gene.
Vulliamy T, et al.
Hum Mutat 2 : 159-167. 1993
47G6PD, ERVK2, ERVK3, DDB1, TAZ, ATP6AP1, GDI1, FAM50A, FAM3A, PLXNA3, ATP6AP1
Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection.
Sedlacek Z, Korn B, Konecki DS, Siebenhaar R, Coy JF, Kioschis P, Poustka A.
Hum Mol Genet 2(11):1865-9. 1993
48G6PD
5' structure and expression of human glucose-6-phosphate dehydrogenase mRNA.
Kanno H, Kondoh T, Yoshida A.
DNA Cell Biol 12(3):209-15. 1993
49G6PD, G6PDD
Molecular abnormality of a Japanese glucose-6-phosphate dehydrogenase variant (G6PD Tokyo) associated with hereditary non-spherocytic hemolytic anemia.
Hirono A, et al.
Hum Genet 88 : 347-348. 1992
50G6PD, G6PDD
Molecular heterogeneity underlying the G6PD Mediterranean phenotype.
Corcoran CM, et al.
Hum Genet 88 : 688-690. 1992
51G6PD, G6PDD
New glucose-6-phosphate dehydrogenase mutations from various ethnic groups.
Beutler E, et al.
Blood 80 : 255-256. 1992
52G6PD, G6PDD
Diverse point mutations result in glucose-6-phosphate dehydrogenase (G6PD) polymorphism in Taiwan.
Tang TK, et al.
Blood 79 : 2135-2140. 1992
53G6PD
Molecular abnormalities of a human glucose-6-phosphate dehydrogenase variant associated with undetectable enzyme activity and immunologically cross-reacting material.
Maeda M, et al.
Am J Hum Genet 51 : 386-395. 1992
54G6PD, G6PDD
Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency by natural and amplification created restriction sites : five mutations account for most G6PD deficiency cases in Taiwan.
Chang JG, et al.
Blood 80 : 1079-1082. 1992
55G6PD, G6PDD
A to G substitution identified in exon 2 of the G6PD gene among G6PD deficient Chinese.
Chao L, et al.
Nucleic Acids Res 19 : 6056. 1991
56APOC2, G6PD
PCR primers for human chromosomes: reagents for the rapid analysis of somatic cell hybrids.
Theune S, et al.
Genomics 9 : 511-516. 1991
57G6PD, G6PDD
Glucose-6-phosphate dehydrogenase deficiency.
Beutler E.
N Engl J Med 324 : 169-174. 1991
58G6PD
DNA sequence abnormalities of human glucose-6-phosphate dehydrogenase variants.
Beutler E, et al.
J Biol Chem 266 : 4145-4150. 1991
59G6PD, GMPR
Origin of fused glucose-6-phosphate dehydrogenase.
Yoshida A, et al.
Cell 62 : 11-12. 1990
60G6PD
Human red cell glucose-6-phosphate dehydrogenase is encoded only on the X chromosome.
Mason PJ, et al.
Cell 62 : 9-10. 1990
61G6PD
Human red cell glucose-6-phosphate dehydrogenase : all active enzyme has sequence predicted by the X chromosome-encoded cDNA.
Beutler E, et al.
Cell 62 : 7-9. 1990
62G6PD, G6PDD
The NT 1311 polymorphism of G6PD : G6PD Mediterranean mutation may have originated independently in Europe and Asia.
Beutler E, et al.
Am J Hum Genet 47 : 1008-1012. 1990
63G6PD, G6PDD
Linkage between a PvuII restriction fragment length polymorphism and G6PD A-202A/376G: evidence for a single origin of the common G6PD A-mutation.
Beutler E, et al.
Hum Genet 85 : 9-11. 1990
64G6PD, G6PDD
G6PD Canton a common deficient variant in South East Asia caused by a 459 Arg-Leu mutation.
Stevens DJ, et al.
Nucleic Acids Res 18 : 7190. 1990
65GMPR, G6PD
The human mRNA that provides the N-terminus of chimeric G6PD encodes GMP reductase.
Henikoff S, et al.
Cell 58 : 1021-1022. 1989
66G6PD, GMPR
Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase.
Kanno H, et al.
Cell 58 : 595-606. 1989
67G6PD
Glucose-6-phosphate dehydrogenase : new perspectives.
Beutler E.
Blood 73 : 1397-1401. 1989
68G6PD, F8, RGCP@, DXYS61X, DXYS61Y, DXYS64X, DXYS64Y
Toward a physical map of the Xq28 region in man: linking color vision, G6PD, and coagulation factor VIII genes to an X-Y homology region.
Arveiler B, et al.
Genomics 4 : 460-471. 1989
69G6PD
An extensive search for RFLP in the human glucose-6-phosphate dehydrogenase locus has revealed a silent mutation in the coding sequence.
D'Urso M, et al.
Am J Hum Genet 42 : 735-741. 1988
70G6PD
RFLP of the X chromosome-linked glucose-6-phosphate dehydrogenase locus in blacks.
Yoshida A, et al.
Am J Hum Genet 42 : 872-876. 1988
71F8, FRAXA, G6PD
Detailed ordering of markers localising to the Xq26-Xqter region of the human X chromosome by the use of an interspecific Mus spretus mouse cross. Characterization of a panel of somatic cell hybrids for regional mapping of the mouse X chromosome.
Avner P, et al.
Proc Natl Acad Sci U S A 84 : 5330-5334. 1987
72DXS98, DXS105, DXS152, DXS115, F8, G6PD
Physical mapping studies on the human X chromosome in the region Xq27-Xqter.
Patterson M, et al.
Genomics 1 : 297-306. 1987
73G6PD
Structural analysis of the X-linked gene encoding human glucose 6-phosphate dehydrogenase.
Martini G, et al.
EMBO J 5 : 1849-1855. 1986
74G6PD
Isolation of human glucose-6-phosphate dehydrogenase (G6PD) cDNA clones: primary structure of the protein and unusual 5' non-coding region.
Persico MG, et al.
Nucleic Acids Res 14 : 2511-2522. 1986
75G6PD
Human glucose-6-phosphate dehydrogenase : primary structure and cDNA cloning.
Takizawa Y, et al.
Proc Natl Acad Sci U S A 83 : 4157-4161. 1986
76G6PD
Cytological mapping of the human glucose-6-phosphate dehydrogenase gene distal to the fragile-X site suggests a high rate of meiotic recombination across this site.
Szabo P, et al.
Proc Natl Acad Sci U S A 81 : 7855-7859. 1984
77G6PD
Specific methylation pattern at the 3' end of the human housekeeping gene for glucose 6-phosphate dehydrogenase.
Toniolo D, et al.
EMBO J 3 : 1987-1995. 1984
78G6PD, HPRT1
Localisation of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation.
Pai GS, et al.
Proc Natl Acad Sci U S A 77 : 2810-2813. 1980
79G6PD, PGK1
An (Xq+;9p-) translocation suggests the assignment of G6PD, HPRT, and PGK to the long arm of the X chromosome in somatic cell hybrids.
Shows TB, et al.
Cytogenet Cell Genet 13 : 146-149. 1974