| 1 | FYN, NOS2
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| Tyrosine kinase Fyn regulates iNOS expression in LPS-stimulated astrocytes via modulation of ERK phosphorylation.
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| Ko HM, Lee SH, Bang M, Kim KC, Jeon SJ, Park YM, Han SH, Kim HY, Lee J, Shin CY.
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| Biochem Biophys Res Commun 495(1):1214-1220. doi: 10.1016/j.bbrc.2017.11.143. Epub 2017 Nov 26.
2018
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| 2 | DDN, FYN, MAGI2
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| Glomerulosclerosis Induced by Deficiency of Membrane-Associated Guanylate Kinase Inverted 2 in Kidney Podocytes.
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| Shirata N, Ihara KI, Yamamoto-Nonaka K, Seki T, Makino SI, Oliva Trejo JA, Miyake T, Yamada H, Campbell KN, Nakagawa T, Mori K, Yanagita M, Mundel P, Nishimori K, Asanuma K.
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| J Am Soc Nephrol 28(9):2654-2669. doi: 10.1681/ASN.2016121356. Epub 2017 May 24.
2017
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| 3 | FLT3, FYN
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| FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.
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| Chougule RA, Kazi JU, Rönnstrand L.
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| Oncotarget ncotarget. 2016 Feb 2. doi: 10.18632/oncotarget.7128. [Epub ahead of print]
2016
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| 4 | FYN, MOBP
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| MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes.
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| Schäfer I, Müller C, Luhmann HJ, White R.
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| J Cell Sci. Mar 1;129(5):930-42. doi: 10.1242/jcs.172148. Epub 2016 Jan 22. 2016
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| 5 | FYN, NCK1, NPHS1
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| Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.
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| New LA, Keyvani Chahi A, Jones N.
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| J Biol Chem 288(3):1500-10. doi: 10.1074/jbc.M112.439463. Epub 2012 Nov 27. 2013
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| 6 | CAMK2D, FYN
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| Vascular smooth muscle cell motility is mediated by a physical and functional interaction of Ca2+/calmodulin-dependent protein kinase IIδ2 and Fyn.
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| Ginnan R, Zou X, Pfleiderer PJ, Mercure MZ, Barroso M, Singer HA.
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| J Biol Chem 288(41):29703-12. doi: 10.1074/jbc.M113.477257. Epub 2013 Sep 3.
2013
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| 7 | AGAP2, FYN, STAT5A
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| Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction.
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| Tse MC, Liu X, Yang S, Ye K, Chan CB.
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| Mol Cell Biol 33(9):1797-808. doi: 10.1128/MCB.01410-12. Epub 2013 Feb 25.
2013
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| 8 | FYN, SH2D1A
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| The adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis.
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| Zhong MC, Veillette A.
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| J Biol Chem 288(44):31423-36. doi: 10.1074/jbc.M113.473736. Epub 2013 Sep 17.
2013
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| 9 | FYN, RAB11A, UNC119
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| UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis.
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| Lee Y, Chung S, Baek IK, Lee TH, Paik SY, Lee J.
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| Cell Cycle 12(8):1303-15. doi: 10.4161/cc.24404. Epub 2013 Mar 27.
2013
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| 10 | FYN, RHOA, SLIT2
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| Slit2 regulates the dispersal of oligodendrocyte precursor cells via Fyn/RhoA signaling.
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| Liu X, Lu Y, Zhang Y, Li Y, Zhou J, Yuan Y, Gao X, Su Z, He C.
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| J Biol Chem 287(21):17503-16. doi: 10.1074/jbc.M111.317610. Epub 2012 Mar 20.
2012
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| 11 | FYB1, FYN, TMEM47
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| TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation.
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| Azhibekov TA, Wu Z, Padiyar A, Bruggeman LA, Simske JS.
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| Am J Physiol Cell Physiol 301(6):C1351-9. Epub 2011 Aug 31. 2011
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| 12 | FYN
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| The role of Fyn kinase in the release from metaphase in mammalian oocytes.
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| Levi M, Shalgi R.
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| Mol Cell Endocrinol 314(2):228-33. Epub 2009 Sep 4. Review.PMID: 19733625 2010
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| 13 | FYN, LYN, SRC, YES1
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| Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.
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| Sato I, Obata Y, Kasahara K, Nakayama Y, Fukumoto Y, Yamasaki T, Yokoyama KK, Saito T, Yamaguchi N.
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| J Cell Sci 122(Pt 7):965-75. Epub 2009 Mar 3.
2009
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| 14 | FYN, PTPRT
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| Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.
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| Lim SH, Kwon SK, Lee MK, Moon J, Jeong DG, Park E, Kim SJ, Park BC, Lee SC, Ryu SE, Yu DY, Chung BH, Kim E, Myung PK, Lee JR.
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| EMBO J 28(22):3564-78. Epub 2009 Oct 8.PMID: 19816407 2009
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| 15 | FYN
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| Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.
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| Brignatz C, Paronetto MP, Opi S, Cappellari M, Audebert S, Feuillet V, Bismuth G, Roche S, Arold ST, Sette C, Collette Y.
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| Mol Cell Biol 29(24):6438-48. Epub 2009 Oct 5.PMID: 19805512 2009
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| 16 | FYN, PTPRA
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| Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.
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| Wang PS, Wang J, Xiao ZC, Pallen CJ.
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| J Biol Chem 284(48):33692-702. doi: 10.1074/jbc.M109.061770.
2009
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| 17 | FYN, KIRREL, TJP1
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| Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.
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| Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D.
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| J Biol Chem 283(51):35579-89. Epub 2008 Oct 14.PMID: 18922801 2008
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| 18 | FYN, LRP8, OMA1
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| Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.
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| Hoe HS, Minami SS, Makarova A, Lee J, Hyman BT, Matsuoka Y, Rebeck GW.
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| J Biol Chem 283(10):6288-99. Epub 2007 Dec 18.PMID: 18089558 2008
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| 19 | FYN
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| BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia.
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| Ban K, Gao Y, Amin HM, Howard A, Miller C, Lin Q, Leng X, Munsell M, Bar-Eli M, Arlinghaus RB, Chandra J.
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| Blood 111(5):2904-8. Epub 2008 Jan 7.PMID: 18180382 2008
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| 20 | DAB1, FYN, LRP8
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| Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing.
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| Hoe HS, Minami SS, Makarova A, Lee J, Hyman BT, Matsuoka Y, Rebeck GW.
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| J Biol Chem 283(10):6288-99. Epub 2007 Dec 18.
2008
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| 21 | FYN, HTR6
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| The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn.
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| Yun HM, Kim S, Kim HJ, Kostenis E, Kim JI, Seong JY, Baik JH, Rhim H.
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| J Biol Chem 282(8):5496-505. Epub 2006 Dec 22.PMID: 17189269 2007
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| 22 | FYN
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| Structure of human Fyn kinase domain complexed with staurosporine.
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| Kinoshita T, Matsubara M, Ishiguro H, Okita K, Tada T.
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| Biochem Biophys Res Commun 346(3):840-4. Epub 2006 Jun 13. 2006
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| 23 | SH2D1A, LYP, FYN
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| Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP.
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| Hare NJ, Ma CS, Alvaro F, Nichols KE, Tangye SG.
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| Int Immunol 18(7):1055-65. Epub 2006 May 23. 2006
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| 24 | ARHGAP33, FYN
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| Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP.
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| Liu H, Nakazawa T, Tezuka T, Yamamoto T.
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| J Biol Chem 281(33):23611-9. Epub 2006 Jun 15.
2006
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| 25 | FYN, SRC, YES1
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| Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events.
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| Werdich XQ, Penn JS.
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| Angiogenesis 8(4):315-26. Epub 2006 Jan 7.
2005
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| 26 | FYB1, FYN, LCP2
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| Identification of Fyn-binding proteins in MC/9 mast cells using mass spectrometry.
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| Nahm DH, Tkaczyk C, Fukuishi N, Colucci-Guyon E, Gilfillan AM, Metcalfe DD.
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| Biochem Biophys Res Commun 310(1):202-8. 2003
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| 27 | ADD2, FYN
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| Interaction of the SH2 domain of Fyn with a cytoskeletal protein, beta-adducin.
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| Shima T, Okumura N, Takao T, Satomi Y, Yagi T, Okada M, Nagai K.
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| J Biol Chem 276(45):42233-40. 2001
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| 28 | FYN, GRB2, SF1, QKI
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| The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins.
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| Ebersole TA, Chen Q, Justice MJ, Artzt K.
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| Nat Genet 12(3):260-5. 1996
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| 29 | EWSR1, FMR1, FXR1, FXR2, FYN, GRB2, HDLBP, HNRNPA1, HNRNPA2B1, NCL, PTBP1, RBMXP1, RBMY1A1, RBMY1A2, RBM3, SF1
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| Conserved structures and diversity of functions of RNA-binding proteins.
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| Burd CG, et al.
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| Science 265 : 615-621. 1994
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| 30 | FYN
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| Regional assignment of a novel yes-related protooncogene, syn, to human chromosome 6 at band q21.
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| Yoshida MC, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 724. 1987
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| 31 | FYN
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| yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.
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| Semba K, et al.
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| Proc Natl Acad Sci U S A 83 : 5459-5463. 1986
|