Citations for
1FUT1, FUT2, FUT3, FUT6, FUT8, GFUS
Altered expression of fucosylation pathway genes is associated with poor prognosis and tumor metastasis in non‑small cell lung cancer.
Park S, Lim JM, Chun JN, Lee S, Kim TM, Kim DW, Kim SY, Bae DJ, Bae SM, So I, Kim HG, Choi JY, Jeon JH.
Int J Oncol. Feb;56(2):559-567. doi: 10.3892/ijo.2019.4953. Epub 2019 Dec 2020
2FUT3
High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma.
Meng L, Xu L, Yang Y, Zhou L, Chang Y, Shi T, Tan C, An H, Zhu Y, Xu J.
Oncotarget May 9;8(37):61036-61047. doi: 10.18632/oncotarget.17717. eCollection 2017 Sep 22 2017
3FUT2, FUT3
How Fucose of Blood Group Glycotopes Programs Human Gut Microbiota.
Kononova SV.
Biochemistry (Mosc) Sep;82(9):973-989. doi: 10.1134/S0006297917090012 2017
4FUT2, FUT3, FUT6
Variation at ABO histo-blood group and FUT loci and diffuse and intestinal gastric cancer risk in a European population.
Duell EJ, Bonet C, Muñoz X, Lujan-Barroso L, Weiderpass E, Boutron-Ruault MC, Racine A, Severi G, Canzian F, Rizzato C, Boeing H, Overvad K, Tjønneland A, Argüelles M, Sánchez-Cantalejo E, Chamosa S, Huerta JM, Barricarte A, Khaw KT, Wareham N, Travis RC, Trichopoulou A, Trichopoulos D, Yiannakouris N, Palli D, Agnoli C, Tumino R, Naccarati A, Panico S, Bueno-de-Mesquita HB, Siersema PD, Peeters PH, Ohlsson B, Lindkvist B, Johansson I, Ye W, Johansson M, Fenger C, Riboli E, Sala N, González CA.
Int J Cancer. Feb 15;136(4):880-93. doi: 10.1002/ijc.29034. Epub 2014 Jul 1 2015
5FUT3, FUT6
Fucosylated TGF-β receptors transduces a signal for epithelial-mesenchymal transition in colorectal cancer cells.
Hirakawa M, Takimoto R, Tamura F, Yoshida M, Ono M, Murase K, Sato Y, Osuga T, Sato T, Iyama S, Miyanishi K, Takada K, Hayashi T, Kobune M, Kato J.
Br J Cancer. Jan 7;110(1):156-63. doi: 10.1038/bjc.2013.699. Epub 2013 Nov 19 2014
6FUT3
α3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration.
Brazil JC, Liu R, Sumagin R, Kolegraff KN, Nusrat A, Cummings RD, Parkos CA, Louis NA.
J Immunol. Nov 1;191(9):4804-17. doi: 10.4049/jimmunol.1301307. Epub 2013 Sep 25 2013
7FUT2, FUT3
Histo-blood group gene polymorphisms as potential genetic modifiers of the development of coronary artery lesions in patients with Kawasaki disease.
Yamamura K, Ihara K, Ikeda K, Nagata H, Mizuno Y, Hara T.
Int J Immunogenet. Apr;39(2):119-25. doi: 10.1111/j.1744-313X.2011.01065.x. Epub 2011 Nov 25 2012
8FUT2, FUT3
Polymorphisms of Lewis and Secretor genes are related to breast cancer and metastasis in axillary lymph nodes.
Teresa DB, Santos RA, Takahashi CS, Carrara HH, Moreira HW, Mattos LC, Lia-Neto N, Cunha LA, Bassi CL, Soares EG, Donadi EA, Mello ER, Soares CP.
Tumour Biol 31(5):401-9. Epub 2010 Jun 1.PMID: 20514537 2010
9FUT3, ST6GALNAC6
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.
Tsuchida A, Okajima T, Furukawa K, Ando T, Ishida H, Yoshida A, Nakamura Y, Kannagi R, Kiso M, Furukawa K.
J Biol Chem 278(25):22787-94. Epub 2003 Mar 31. 2003
10FUT3
Localization, purification and specificity of the full-length membrane-bound form of human recombinant alpha 1,3/4-fucosyltransferase from BHK-21B cells.
Sousa VL, Costa MT, Palma AS, Enguita F, Costa J.
Biochem J 357(Pt 3):803-10. 2001
11LE, FUT3
Five novel missense mutations of the Lewis gene (FUT3) in African (Xhosa) and Caucasian populations in South Africa.
Pang H, et al.
Hum Genet 102 : 675-680. 1998
12FUT3
Human alpha1,3/4-fucosyltransferases. III. A Lys/Arg residue located within the alpha1,3-FucT motif is required for activity but not substrate binding.
Sherwood AL, et al.
J Biol Chem 273 : 25256-25260. 1998
13FUT3
Human alpha1,3/4-fucosyltransferases. I. Identification of amino acids involved in acceptor substrate binding by site-directed mutagenesis.
Nguyen AT, et al.
J Biol Chem 273 : 25244-25249. 1998
14FUT3, FUT4, FUT5, FUT6
Physical maps of human alpha(1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.
McCurley RS, et al.
Genomics 26 : 142-146. 1995
15FUT1, FUT2, FUT3, FUT5, FUT6
Relative positions of two clusters of human a-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19.
Reguigne-Arnould I, et al.
Cytogenet Cell Genet 71 : 158-162. 1995
16FUT3
Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.
Mollicone R, Reguigne I, Kelly RJ, Fletcher A, Watt J, Chatfield S, Aziz A, Cameron HS, Weston BW, Lowe JB.
J Biol Chem 269(33):20987-94 1994
17FUT3,FUT6
Human alpha-1,3 fucosyltransferase (FucT-VI) gene is located at only 13 Kb 3' to the Lewis type fucosyltransferase (FucT-III) gene on chromosome 19.
Nishihara S, et al.
Biochem Biophys Res Commun 190 : 42-46. 1993
18FUT3
Isolation of a novel human alpha(1,3) fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha(1,3/1,4) fucosyltransferase gene.
Weston BW, et al.
J Biol Chem 267 : 4152-4160. 1992
19FUT3, FUT4
Chromosome 11q localization of one of the three expected genes for the human alpha-3-fucosyltransferases, by somatic hybridization.
Couillin P, et al.
Cytogenet Cell Genet 56 : 108-111. 1991
20FUT3
A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4) fucosyltransferase.
Kukowska-Latallo JF, et al.
Genes Dev 4 : 1288-1303. 1990
21CD5, B3GAT1, FUT3
Localization of human myeloid-associated surface antigen detected by a panel of 20 monoclonal antibodies to the q12-qter region of chromosome 11.
van Kessel AG, Tetteroo P, van Agthoven T, Paulussen R, van Dongen J, Hagemeijer A, von dem Borne A.
J Immunol 133(3):1265-9. 1984