1 | AKT1, FSCN1, HBEGF, SOX2
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| SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
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| Xiao W, Zheng S, Xie X, Li X, Zhang L, Yang A, Wang J, Tang H, Xie X.
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| Mol Ther Oncolytics. Mar 13;17:118-129. doi: 10.1016/j.omto.2020.03.001. 2020
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2 | FSCN1
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| FSCN1 is an effective marker of poor prognosis and a potential therapeutic target in human tongue squamous cell carcinoma. 2019
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| Chen Y, Tian T, Li ZY, Wang CY, Deng R, Deng WY, Yang AK, Chen YF, Li H.
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| Cell Death Dis. May 1;10(5):356. doi: 10.1038/s41419-019-1574-5 2019
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3 | FSCN1, SNAI1
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| FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells
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| Li J, Zhang S, Pei M, Wu L, Liu Y, Li H, Lu J, Li X.
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| Cell Physiol Biochem. 49(5):1766-1777. doi: 10.1159/000493622. Epub 2018 Sep 19. 2018
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4 | FSCN1
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| FSCN1 predicts survival and is regulated by a PI3K-dependent mechanism in renal cell carcinoma
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| Zhang M, Zhao Z, Duan X, Chen P, Peng Z, Qiu H.
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| J Cell Physiol. Jun;233(6):4748-4758. doi: 10.1002/jcp.26264. Epub 2018 Jan 15. 2018
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5 | CTTN, FSCN1
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| Cortactin and fascin-1 regulate extracellular vesicle release by controlling endosomal trafficking or invadopodia formation and function
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| Beghein E, Devriese D, Van Hoey E, Gettemans J.
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| Sci Rep. Oct 23;8(1):15606. doi: 10.1038/s41598-018-33868-z. 2018
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6 | FSCN1, NSMCE3, VIM
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| Identification of Novel MAGE-G1-Interacting Partners in Retinoic Acid-Induced P19 Neuronal Differentiation Using SILAC-Based Proteomics.
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| Liu Y, Chen Y, Lin S, Yang S, Liu S.
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| Sci Rep 7:44699. doi: 10.1038/srep44699.
2017
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7 | FSCN1
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| The role of FSCN1 in migration and invasion of pituitary adenomas.
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| Liu C, Gao H, Cao L, Gui S, Liu Q, Li C, Li D, Gong L, Zhang Y.
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| Mol Cell Endocrinol. Jan 5;419:217-24. doi: 10.1016/j.mce.2015.10.021. Epub 2015 Oct 29 2016
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8 | BMI1, FSCN1
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| Significance of BMI1 and FSCN1 expression in colorectal cancer
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| Alajez NM.
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| Saudi J Gastroenterol Jul-Aug;22(4):288-93. doi: 10.4103/1319-3767.187602. 2016
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9 | FSCN1
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| Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
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| Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q.
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| Nat Commun Aug 22;7:12603. doi: 10.1038/ncomms12603. 2016
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10 | FSCN1, SYNE2
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| Fascin Regulates Nuclear Movement and Deformation in Migrating Cells.
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| Jayo A, Malboubi M, Antoku S, Chang W, Ortiz-Zapater E, Groen C, Pfisterer K, Tootle T, Charras G, Gundersen GG, Parsons M.
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| Dev Cell. Aug 22;38(4):371-83. doi: 10.1016/j.devcel.2016.07.021 2016
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11 | FSCN1
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| Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2
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| Saad A, Bijian K, Qiu D, da Silva SD, Marques M, Chang CH, Nassour H, Ramotar D, Damaraju S, Mackey J, Bismar T, Witcher M, Alaoui-Jamali MA.
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| Sci Rep. Nov 7;6:36699. doi: 10.1038/srep36699. 2016
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12 | FSCN1
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| Fascin 1 is an actin filament-bundling protein that regulates ectoplasmic specialization dynamics in the rat testis.
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| Gungor-Ordueri NE, Celik-Ozenci C, Cheng CY.
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| Physiol Endocrinol Metab. Nov 1;307(9):E738-53. doi: 10.1152/ajpendo.00113.2014. Epub 2014 Aug 26. 2014
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13 | FSCN1
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| Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
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| Tan VY, Lewis SJ, Adams JC, Martin RM.
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| BMC Med. Feb 26;11:52. doi: 10.1186/1741-7015-11-52 2013
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14 | FSCN1
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| The role of fascin in migration and invasion of urothelial carcinoma of the bladder.
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| Bi JB, Zhu Y, Chen XL, Yu M, Zhang YX, Li BX, Sun JW, Shen HL, Kong CZ.
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| Urol Int. 91(2):227-35. doi: 10.1159/000346559. Epub 2013 Feb 20 2013
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15 | FSCN1
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| Fascin is a predictor for invasiveness and recurrence of urothelial carcinoma of bladder.
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| Bi J, Chen X, Zhang Y, Li B, Sun J, Shen H, Kong C.
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| Urol Oncol. Sep;30(5):688-94. doi: 10.1016/j.urolonc.2010.08.001. Epub 2010 Oct 2. 2012
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16 | FSCN1, TGFB1
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| Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells.
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| Sun J, He H, Xiong Y, Lu S, Shen J, Cheng A, Chang WC, Hou MF, Lancaster JM, Kim M, Yang S.
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| J Biol Chem 286(45):38865-75. doi: 10.1074/jbc.M111.270413. Epub 2011 Sep 13.
2011
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17 | CFL1, FSCN1
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| Cofilin cooperates with fascin to disassemble filopodial actin filaments.
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| Breitsprecher D, Koestler SA, Chizhov I, Nemethova M, Mueller J, Goode BL, Small JV, Rottner K, Faix J.
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| J Cell Sci 124(Pt 19):3305-18. doi: 10.1242/jcs.086934.
2011
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18 | FSCN1
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| Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein.
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| Sedeh RS, Fedorov AA, Fedorov EV, Ono S, Matsumura F, Almo SC, Bathe M.
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| J Mol Biol 400(3):589-604. Epub 2010 Apr 29.PMID: 20434460 2010
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19 | FSCN1
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| Upregulated fascin1 in non-small cell lung cancer promotes the migration and invasiveness, but not proliferation.
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| Zhao J, Zhou Y, Zhang Z, Tian F, Ma N, Liu T, Gu Z, Wang Y.
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| Cancer Lett 290(2):238-47. Epub 2009 Oct 12.PMID: 19819618 2010
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20 | FSCN1
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| Migrastatin analogues target fascin to block tumour metastasis.
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| Chen L, Yang S, Jakoncic J, Zhang JJ, Huang XY.
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| Nature 464(7291):1062-6.PMID: 20393565 2010
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21 | FSCN1
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| Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.
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| Hashimoto Y, Loftis DW, Adams JC.
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| PLoS One 4(4):e5130. Epub 2009 Apr 2.PMID: 19340314 2009
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22 | FSCN1, FSCN2, FSCN3
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| The human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer.
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| Bros M, Ross XL, Pautz A, Reske-Kunz AB, Ross R.
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| J Immunol 171(4):1825-34. 2003
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23 | FSCN2, FSCN3, FSCN1
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| Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.
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| Tubb BE, Bardien-Kruger S, Kashork CD, Shaffer LG, Ramagli LS, Xu J, Siciliano MJ, Bryan J.
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| Genomics 65(2):146-56. 2000
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24 | FSCN1, FSCN2, FSCN3
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| The actin-bundling protein fascin is involved in the formation of dendritic processes in maturing epidermal Langerhans cells.
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| Ross R, Ross XL, Schwing J, Langin T, Reske-Kunz AB.
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| J Immunol 160(8):3776-82. 1998
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25 | FSCN1
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| Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin.
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| Ono S, Yamakita Y, Yamashiro S, Matsudaira PT, Gnarra JR, Obinata T, Matsumura F.
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| J Biol Chem 272(4):2527-33. 1997
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26 | FSCN1
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| cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.
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| Duh FM, et al.
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| DNA Cell Biol 13 : 821-827. 1994
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27 | FSCN1
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| Fascin, an echinoid actin-bundling protein, is a homolog of the Drosophila singed gene product.
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| Bryan J, Edwards R, Matsudaira P, Otto J, Wulfkuhle J.
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| Proc Natl Acad Sci U S A 90(19):9115-9. 1993
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