Citations for
1AKT1, FSCN1, HBEGF, SOX2
SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
Xiao W, Zheng S, Xie X, Li X, Zhang L, Yang A, Wang J, Tang H, Xie X.
Mol Ther Oncolytics. Mar 13;17:118-129. doi: 10.1016/j.omto.2020.03.001. 2020
2FSCN1
FSCN1 is an effective marker of poor prognosis and a potential therapeutic target in human tongue squamous cell carcinoma. 2019
Chen Y, Tian T, Li ZY, Wang CY, Deng R, Deng WY, Yang AK, Chen YF, Li H.
Cell Death Dis. May 1;10(5):356. doi: 10.1038/s41419-019-1574-5 2019
3FSCN1, SNAI1
FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells
Li J, Zhang S, Pei M, Wu L, Liu Y, Li H, Lu J, Li X.
Cell Physiol Biochem. 49(5):1766-1777. doi: 10.1159/000493622. Epub 2018 Sep 19. 2018
4FSCN1
FSCN1 predicts survival and is regulated by a PI3K-dependent mechanism in renal cell carcinoma
Zhang M, Zhao Z, Duan X, Chen P, Peng Z, Qiu H.
J Cell Physiol. Jun;233(6):4748-4758. doi: 10.1002/jcp.26264. Epub 2018 Jan 15. 2018
5CTTN, FSCN1
Cortactin and fascin-1 regulate extracellular vesicle release by controlling endosomal trafficking or invadopodia formation and function
Beghein E, Devriese D, Van Hoey E, Gettemans J.
Sci Rep. Oct 23;8(1):15606. doi: 10.1038/s41598-018-33868-z. 2018
6FSCN1, NSMCE3, VIM
Identification of Novel MAGE-G1-Interacting Partners in Retinoic Acid-Induced P19 Neuronal Differentiation Using SILAC-Based Proteomics.
Liu Y, Chen Y, Lin S, Yang S, Liu S.
Sci Rep 7:44699. doi: 10.1038/srep44699. 2017
7FSCN1
The role of FSCN1 in migration and invasion of pituitary adenomas.
Liu C, Gao H, Cao L, Gui S, Liu Q, Li C, Li D, Gong L, Zhang Y.
Mol Cell Endocrinol. Jan 5;419:217-24. doi: 10.1016/j.mce.2015.10.021. Epub 2015 Oct 29 2016
8BMI1, FSCN1
Significance of BMI1 and FSCN1 expression in colorectal cancer
Alajez NM.
Saudi J Gastroenterol Jul-Aug;22(4):288-93. doi: 10.4103/1319-3767.187602. 2016
9FSCN1
Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation
Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q.
Nat Commun Aug 22;7:12603. doi: 10.1038/ncomms12603. 2016
10FSCN1, SYNE2
Fascin Regulates Nuclear Movement and Deformation in Migrating Cells.
Jayo A, Malboubi M, Antoku S, Chang W, Ortiz-Zapater E, Groen C, Pfisterer K, Tootle T, Charras G, Gundersen GG, Parsons M.
Dev Cell. Aug 22;38(4):371-83. doi: 10.1016/j.devcel.2016.07.021 2016
11FSCN1
Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2
Saad A, Bijian K, Qiu D, da Silva SD, Marques M, Chang CH, Nassour H, Ramotar D, Damaraju S, Mackey J, Bismar T, Witcher M, Alaoui-Jamali MA.
Sci Rep. Nov 7;6:36699. doi: 10.1038/srep36699. 2016
12FSCN1
Fascin 1 is an actin filament-bundling protein that regulates ectoplasmic specialization dynamics in the rat testis.
Gungor-Ordueri NE, Celik-Ozenci C, Cheng CY.
Physiol Endocrinol Metab. Nov 1;307(9):E738-53. doi: 10.1152/ajpendo.00113.2014. Epub 2014 Aug 26. 2014
13FSCN1
Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
Tan VY, Lewis SJ, Adams JC, Martin RM.
BMC Med. Feb 26;11:52. doi: 10.1186/1741-7015-11-52 2013
14FSCN1
The role of fascin in migration and invasion of urothelial carcinoma of the bladder.
Bi JB, Zhu Y, Chen XL, Yu M, Zhang YX, Li BX, Sun JW, Shen HL, Kong CZ.
Urol Int. 91(2):227-35. doi: 10.1159/000346559. Epub 2013 Feb 20 2013
15FSCN1
Fascin is a predictor for invasiveness and recurrence of urothelial carcinoma of bladder.
Bi J, Chen X, Zhang Y, Li B, Sun J, Shen H, Kong C.
Urol Oncol. Sep;30(5):688-94. doi: 10.1016/j.urolonc.2010.08.001. Epub 2010 Oct 2. 2012
16FSCN1, TGFB1
Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells.
Sun J, He H, Xiong Y, Lu S, Shen J, Cheng A, Chang WC, Hou MF, Lancaster JM, Kim M, Yang S.
J Biol Chem 286(45):38865-75. doi: 10.1074/jbc.M111.270413. Epub 2011 Sep 13. 2011
17CFL1, FSCN1
Cofilin cooperates with fascin to disassemble filopodial actin filaments.
Breitsprecher D, Koestler SA, Chizhov I, Nemethova M, Mueller J, Goode BL, Small JV, Rottner K, Faix J.
J Cell Sci 124(Pt 19):3305-18. doi: 10.1242/jcs.086934. 2011
18FSCN1
Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein.
Sedeh RS, Fedorov AA, Fedorov EV, Ono S, Matsumura F, Almo SC, Bathe M.
J Mol Biol 400(3):589-604. Epub 2010 Apr 29.PMID: 20434460 2010
19FSCN1
Upregulated fascin1 in non-small cell lung cancer promotes the migration and invasiveness, but not proliferation.
Zhao J, Zhou Y, Zhang Z, Tian F, Ma N, Liu T, Gu Z, Wang Y.
Cancer Lett 290(2):238-47. Epub 2009 Oct 12.PMID: 19819618 2010
20FSCN1
Migrastatin analogues target fascin to block tumour metastasis.
Chen L, Yang S, Jakoncic J, Zhang JJ, Huang XY.
Nature 464(7291):1062-6.PMID: 20393565 2010
21FSCN1
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.
Hashimoto Y, Loftis DW, Adams JC.
PLoS One 4(4):e5130. Epub 2009 Apr 2.PMID: 19340314 2009
22FSCN1, FSCN2, FSCN3
The human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer.
Bros M, Ross XL, Pautz A, Reske-Kunz AB, Ross R.
J Immunol 171(4):1825-34. 2003
23FSCN2, FSCN3, FSCN1
Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.
Tubb BE, Bardien-Kruger S, Kashork CD, Shaffer LG, Ramagli LS, Xu J, Siciliano MJ, Bryan J.
Genomics 65(2):146-56. 2000
24FSCN1, FSCN2, FSCN3
The actin-bundling protein fascin is involved in the formation of dendritic processes in maturing epidermal Langerhans cells.
Ross R, Ross XL, Schwing J, Langin T, Reske-Kunz AB.
J Immunol 160(8):3776-82. 1998
25FSCN1
Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin.
Ono S, Yamakita Y, Yamashiro S, Matsudaira PT, Gnarra JR, Obinata T, Matsumura F.
J Biol Chem 272(4):2527-33. 1997
26FSCN1
cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.
Duh FM, et al.
DNA Cell Biol 13 : 821-827. 1994
27FSCN1
Fascin, an echinoid actin-bundling protein, is a homolog of the Drosophila singed gene product.
Bryan J, Edwards R, Matsudaira P, Otto J, Wulfkuhle J.
Proc Natl Acad Sci U S A 90(19):9115-9. 1993