Citations for
1FRAS1, FREM1, FREM2
Mesenchymal expression of the FRAS1/FREM2 gene unit is decreased in the developing fetal diaphragm of nitrofen-induced congenital diaphragmatic hernia.
Takahashi T, Friedmacher F, Zimmer J, Puri P.
Pediatr Surg Int 32(2):135-40. doi: 10.1007/s00383-015-3824-7. Epub 2015 Oct 30. 2016
2FRAS1, FREM1, FREM2, GREM1, GRIP1, ITGA8
Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.
Kohl S, Hwang DY, Dworschak GC, Hilger AC, Saisawat P, Vivante A, Stajic N, Bogdanovic R, Reutter HM, Kehinde EO, Tasic V, Hildebrandt F.
J Am Soc Nephrol 25(9):1917-22. doi: 10.1681/ASN.2013101103. Epub 2014 Apr 3. 2014
3FRAS1, FREM2, GRIP1, VWA2
AMACO is a component of the basement membrane-associated Fraser complex.
Richardson RJ, Gebauer JM, Zhang JL, Kobbe B, Keene DR, Karlsen KR, Richetti S, Wohl AP, Sengle G, Neiss WF, Paulsson M, Hammerschmidt M, Wagener R.
J Invest Dermatol 134(5):1313-22. doi: 10.1038/jid.2013.492. Epub 2013 Nov 14. 2014
4FRAS1, FREM2
Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.
Saisawat P, Tasic V, Vega-Warner V, Kehinde EO, GŁnther B, Airik R, Innis JW, Hoskins BE, Hoefele J, Otto EA, Hildebrandt F.
Kidney Int 81(2):196-200. doi: 10.1038/ki.2011.315. Epub 2011 Sep 7. 2012
5FRAS1, FREM1, FREM2, FREM3
The role of Fras1/Frem proteins in the structure and function of basement membrane.
Pavlakis E, Chiotaki R, Chalepakis G.
Int J Biochem Cell Biol 43(4):487-95. Epub 2010 Dec 21. Review. 2011
6FRAS1, HMCN1
Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes.
Carney TJ, Feitosa NM, Sonntag C, Slanchev K, Kluger J, Kiyozumi D, Gebauer JM, Coffin Talbot J, Kimmel CB, Sekiguchi K, Wagener R, Schwarz H, Ingham PW, Hammerschmidt M.
PLoS Genet 6(4):e1000907. 2010
7FRAS1
Molecular interactions in the retinal basement membrane system: a proteomic approach.
Balasubramani M, Schreiber EM, Candiello J, Balasubramani GK, Kurtz J, Halfter W.
Matrix Biol 29(6):471-83. Epub 2010 Apr 18. 2010
8BNAR, FRAS1, FREM1, FREM2
FREM1 mutations cause bifid nose, renal agenesis, and anorectal malformations syndrome.
Alazami AM, Shaheen R, Alzahrani F, Snape K, Saggar A, Brinkmann B, Bavi P, Al-Gazali LI, Alkuraya FS.
Am J Hum Genet 85(3):414-8. 2009
9FRAS1, FRAS2, FREM2
Molecular study of 33 families with Fraser syndrome new data and mutation review.
van Haelst MM, Maiburg M, Baujat G, Jadeja S, Monti E, Bland E, Pearce K; Fraser Syndrome Collaboration Group, Hennekam RC, Scambler PJ.
Am J Med Genet A 146A(17):2252-7. 2008
10FRAS1, FREM2
Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.
Pitera JE, Scambler PJ, Woolf AS.
Hum Mol Genet 17(24):3953-64. Epub 2008 Sep 11. 2008
11FRAS1, GRIP1
Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1.
Long J, Wei Z, Feng W, Yu C, Zhao YX, Zhang M.
J Mol Biol 375(5):1457-68. Epub 2007 Dec 4. 2008
12FRAS1, FREM1, FREM2, FREM3
The Fras1/Frem family of extracellular matrix proteins: structure, function, and association with Fraser syndrome and the mouse bleb phenotype.
Petrou P, Makrygiannis AK, Chalepakis G.
Connect Tissue Res 49(3):277-82. 2008
13FRAS1, FREM1, FREM2, FREM3
Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.
Pavlakis E, Makrygiannis AK, Chiotaki R, Chalepakis G.
Histochem Cell Biol 130(4):785-93. Epub 2008 Jun 18. 2008
14FRAS1, FREM2
Expression of the fras1/frem gene family during zebrafish development and fin morphogenesis.
Gautier P, Naranjo-Golborne C, Taylor MS, Jackson IJ, Smyth I.
Dev Dyn 237(11):3295-304. 2008
15FRAS1, FRAS2
Fraser syndrome: a clinical study of 59 cases and evaluation of diagnostic criteria.
van Haelst MM, Scambler PJ; Fraser Syndrome Collaboration Group, Hennekam RC.
Am J Med Genet A 143(24):3194-203. 2007
16FRAS1, FREM1, FREM2, FREM3
Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.
Petrou P, Pavlakis E, Dalezios Y, Chalepakis G.
Matrix Biol 26(8):652-8. Epub 2007 Jun 6. 2007
17FRAS1
Ultrastructural localization of Fras1 in the sublamina densa of embryonic epithelial basement membranes.
Dalezios Y, Papasozomenos B, Petrou P, Chalepakis G.
Arch Dermatol Res 299(7):337-43. Epub 2007 Jun 19. 2007
18FREM1, FREM2, FRAS1, GRIP1
Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.
Kiyozumi D, Sugimoto N, Sekiguchi K.
Proc Natl Acad Sci U S A 103(32):11981-6. Epub 2006 Jul 31. 2006
19FRAS1
Mutation analysis of the FRAS1 gene demonstrates new mutations in a propositus with Fraser syndrome.
Slavotinek A, Li C, Sherr EH, Chudley AE.
Am J Med Genet A 140(18):1909-14. 2006
20FRAS1
Mitochondrial DNA mutations in a patient with sex reversal and clinical features consistent with Fraser syndrome.
Wong LJ, Lin YH, Suwannarat P, Hsu CH, Kwon HY, Mackowiak S.
Clin Genet 67(3):252-7. 2005
21FRAS1, GRIP1
A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.
Takamiya K, Kostourou V, Adams S, Jadeja S, Chalepakis G, Scambler PJ, Huganir RL, Adams RH.
Nat Genet 36(2):172-7. Epub 2004 Jan 18. 2004
22FRAS1
Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein.
McGregor L, Makela V, Darling SM, Vrontou S, Chalepakis G, Roberts C, Smart N, Rutland P, Prescott N, Hopkins J, Bentley E, Shaw A, Roberts E, Mueller R, Jadeja S, Philip N, Nelson J, Francannet C, Perez-Aytes A, Megarbane A, Kerr B, Wainwright B, Woolf AS, Winter RM, Scambler PJ.
Nat Genet 34(2):203-8. 2003
23FRAS1
Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.
Vrontou S, Petrou P, Meyer BI, Galanopoulos VK, Imai K, Yanagi M, Chowdhury K, Scambler PJ, Chalepakis G.
Nat Genet 34(2):209-14. 2003