Citations for
1FOXP2
FOXP2 Targets Show Evidence of Positive Selection in European Populations.
Ayub Q, Yngvadottir B, Chen Y, Xue Y, Hu M, Vernes SC, Fisher SE, Tyler-Smith C.
Am J Hum Genet 92(5):696-706. doi: 10.1016/j.ajhg.2013.03.019. Epub 2013 Apr 18. 2013
2DEL7Q31, FOXP2
Mosaic 7q31 Deletion Involving FOXP2 Gene Associated With Language Impairment.
Palka C, Alfonsi M, Mohn A, Cerbo R, Franchi PG, Fantasia D, Morizio E, Stuppia L, Calabrese G, Zori R, Chiarelli F, Palka G.
Pediatrics 129(1):e183-8. Epub 2011 Dec 5. 2012
3FOXP2
Imaging genetics of FOXP2 in dyslexia.
Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H.
Eur J Hum Genet 20(2):224-9. doi: 10.1038/ejhg.2011.160. Epub 2011 Sep 7. Erratum in: Eur J Hum Genet. 2012 Jun;20(6):714. 2012
4DISC1, FOXP2
The DISC1 promoter: characterization and regulation by FOXP2.
Walker RM, Hill AE, Newman AC, Hamilton G, Torrance HS, Anderson SM, Ogawa F, Derizioti P, Nicod J, Vernes SC, Fisher SE, Thomson PA, Porteous DJ, Evans KL.
Hum Mol Genet 21(13):2862-72. doi: 10.1093/hmg/dds111. Epub 2012 Mar 20. 2012
5FOXP2
Temporal expression and mitochondrial localization of a Foxp2 isoform lacking the forkhead domain in developing Purkinje cells.
Tanabe Y, Fujiwara Y, Matsuzaki A, Fujita E, Kasahara T, Yuasa S, Momoi T.
J Neurochem 122(1):72-80. doi: 10.1111/j.1471-4159.2011.07524.x. Epub 2011 Nov 3. 2012
6FOXP1, FOXP2
The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in cognitive disorders.
Bacon C, Rappold GA.
Hum Genet 131(11):1687-98. doi: 10.1007/s00439-012-1193-z. Epub 2012 Jun 27. Review. 2012
7DEL7Q31, FOXP2, SPCH1
Phenotype of FOXP2 haploinsufficiency in a mother and son.
Rice GM, Raca G, Jakielski KJ, Laffin JJ, Iyama-Kurtycz CM, Hartley SL, Sprague RE, Heintzelman AT, Shriberg LD.
Am J Med Genet A m J Med Genet A. 2011 Nov 21. doi: 10.1002/ajmg.a.34354. [Epub ahead of print] 2011
8FOXP2, MET
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk.
Mukamel Z, Konopka G, Wexler E, Osborn GE, Dong H, Bergman MY, Levitt P, Geschwind DH.
J Neurosci 31(32):11437-42. 2011
9FOXP2
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.
Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, Ragoussis J, Davies KE, Geschwind DH, Fisher SE.
PLoS Genet 7(7):e1002145. Epub 2011 Jul 7. 2011
10FOXP2, POT1
FOXP2 promotes the nuclear translocation of POT1, but FOXP2(R553H), mutation related to speech-language disorder, partially prevents it.
Tanabe Y, Fujita E, Momoi T.
Biochem Biophys Res Commun 410(3):593-6. Epub 2011 Jun 12. 2011
11FOXP2, MET
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk.
Mukamel Z, Konopka G, Wexler E, Osborn GE, Dong H, Bergman MY, Levitt P, Geschwind DH.
J Neurosci. 31(32):11437-42. 2011
12FOXP2, MEIS2, PBX3
Molecular characterization of the intercalated cell masses of the amygdala: implications for the relationship with the striatum.
Kaoru T, Liu FC, Ishida M, Oishi T, Hayashi M, Kitagawa M, Shimoda K, Takahashi H.
Neuroscience 166(1):220-30. Epub 2009 Dec 14.PMID: 20004711 2010
13FOXP2, PLAUR, SRPX2
Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex.
Roll P, Vernes SC, Bruneau N, Cillario J, Ponsole-Lenfant M, Massacrier A, Rudolf G, Khalife M, Hirsch E, Fisher SE, Szepetowski P.
Hum Mol Genet 19(24):4848-60. Epub 2010 Sep 21. 2010
14FOXP2
The speech and language FOXP2 gene modulates the phenotype of frontotemporal lobar degeneration.
Padovani A, Cosseddu M, Premi E, Archetti S, Papetti A, Agosti C, Bigni B, Cerini C, Paghera B, Bellelli G, Borroni B.
J Alzheimers Dis 22(3):923-31. 2010
15FOXP2
Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.
Chokas AL, Trivedi CM, Lu MM, Tucker PW, Li S, Epstein JA, Morrisey EE.
J Biol Chem. 285(17):13304-13 2010
16FOXP2
FOXP2 as a molecular window into speech and language.
Fisher SE, Scharff C.
Trends Genet 25(4):166-77. Epub 2009 Mar 21. 2009
17FOXA1, FOXA2, FOXA3, FOXC1, FOXC2, FOXO1, FOXO3, FOXO4, FOXP2, FOXP3
The evolution of Fox genes and their role in development and disease.
Hannenhalli S, Kaestner KH.
Nat Rev Genet 10(4):233-40. Review. 2009
18FOXP2
Human-specific transcriptional regulation of CNS development genes by FOXP2.
Konopka G, Bomar JM, Winden K, Coppola G, Jonsson ZO, Gao F, Peng S, Preuss TM, Wohlschlegel JA, Geschwind DH.
Nature 462(7270):213-7.PMID: 19907493 2009
19FOXP1, FOXP2
Characterization of Foxp2-expressing cells in the developing spinal cord.
Morikawa Y, Hisaoka T, Senba E.
Neuroscience 162(4):1150-62. Epub 2009 May 20. 2009
20FOXP2
Multiple transcription start sites for FOXP2 with varying cellular specificities.
Schroeder DI, Myers RM.
Gene 413(1-2):42-8. Epub 2008 Jan 29. 2008
21CNTNAP2, FOXP2, SPCH1, SPCHSL
A Functional Genetic Link between Distinct Developmental Language Disorders.
Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcón M, Oliver PL, Davies KE, Geschwind DH, Monaco AP, Fisher SE.
N Engl J Med Engl J Med. 2008 Nov 5. [Epub ahead of print] 2008
22FOXP2, SPCH1
A Functional Genetic Link between Distinct Developmental Language Disorders.
Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcón M, Oliver PL, Davies KE, Geschwind DH, Monaco AP, Fisher SE.
N Engl J Med Engl J Med. 2008 Nov 5. [Epub ahead of print] 2008
23FOXP2, MEIS2, PBX3
Expression of FOXP2 in the developing monkey forebrain: comparison with the expression of the genes FOXP1, PBX3, and MEIS2.
Takahashi K, Liu FC, Oishi T, Mori T, Higo N, Hayashi M, Hirokawa K, Takahashi H.
J Comp Neurol 509(2):180-9.PMID: 1846160 2008
24FOXP2
Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells.
Fujita E, Tanabe Y, Shiota A, Ueda M, Suwa K, Momoi MY, Momoi T.
Proc Natl Acad Sci U S A. 105(8):3117-22. 2008
25DEL7Q31, SPCH1, AUTS9, FOXP2, WNT2
Deletion of 7q31.1 supports involvement of FOXP2 in language impairment: Clinical report and review.
Lennon PA, Cooper ML, Peiffer DA, Gunderson KL, Patel A, Peters S, Cheung SW, Bacino CA.
Am J Med Genet A [Epub ahead of print] 2007
26FOXP2
Intracellular distribution of a speech/language disorder associated FOXP2 mutant.
Mizutani A, Matsuzaki A, Momoi MY, Fujita E, Tanabe Y, Momoi T.
Biochem Biophys Res Commun 353(4):869-74. Epub 2006 Dec 26. 2007
27FOXP2
Identification of the Transcriptional Targets of FOXP2, a Gene Linked to Speech and Language, in Developing Human Brain.
Spiteri E, Konopka G, Coppola G, Bomar J, Oldham M, Ou J, Vernes SC, Fisher SE, Ren B, Geschwind DH.
Am J Hum Genet 81(6):1144-57. Epub 2007 Oct 31. 2007
28FOXP2
High-Throughput Analysis of Promoter Occupancy Reveals Direct Neural Targets of FOXP2, a Gene Mutated in Speech and Language Disorders.
Vernes SC, Spiteri E, Nicod J, Groszer M, Taylor JM, Davies KE, Geschwind DH, Fisher SE.
Am J Hum Genet 81(6):1232-50. Epub 2007 Oct 31. 2007
29FOXP1, FOXP2
Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.
Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE.
Development 134(10):1991-2000. Epub 2007 Apr 11. 2007
30DEL7Q31, FOXP2, SPCH1
Speech and language impairment and oromotor dyspraxia due to deletion of 7q31 that involves FOXP2.
Zeesman S, Nowaczyk MJ, Teshima I, Roberts W, Cardy JO, Brian J, Senman L, Feuk L, Osborne LR, Scherer SW.
Am J Med Genet A 140(5):509-14. 2006
31FOXP2
Association between FOXP2 polymorphisms and schizophrenia with auditory hallucinations.
Sanjuan J, Tolosa A, Gonzalez JC, Aguilar EJ, Perez-Tur J, Najera C, Molto MD, de Frutos R.
Psychiatr Genet 16(2):67-72. 2006
32FOXP2, DEL7Q31
Absence of a Paternally Inherited FOXP2 Gene in Developmental Verbal Dyspraxia.
Feuk L, Kalervo A, Lipsanen-Nyman M, Skaug J, Nakabayashi K, Finucane B, Hartung D, Innes M, Kerem B, Nowaczyk MJ, Rivlin J, Roberts W, Senman L, Summers A, Szatmari P, Wong V, Vincent JB, Zeesman S, Osborne LR, Cardy JO, Kere J, Scherer SW, Hannula-Jouppi K.
Am J Hum Genet 79(5):965-72. Epub 2006 Sep 27. 2006
33FOXP2, SPCH1
Speech, prosody, and voice characteristics of a mother and daughter with a 7;13 translocation affecting FOXP2.
Shriberg LD, Ballard KJ, Tomblin JB, Duffy JR, Odell KH, Williams CA.
J Speech Lang Hear Res 49(3):500-25. 2006
34FOXP2
Structure of the forkhead domain of FOXP2 bound to DNA.
Stroud JC, Wu Y, Bates DL, Han A, Nowick K, Paabo S, Tong H, Chen L.
Structure. 14(1):159-66. 2006
35FOXP2, SPCH1
Identification of FOXP2 Truncation as a Novel Cause of Developmental Speech and Language Deficits.
Macdermot KD, Bonora E, Sykes N, Coupe AM, Lai CS, Vernes SC, Vargha-Khadem F, McKenzie F, Smith RL, Monaco AP, Fisher SE.
Am J Hum Genet 76(6):1074-80. Epub 2005 Apr 22. 2005
36FOXC2, LPDD,FOXC1, FOXE1, FOXE3, FOXL2, FOXN1, FOXP2, FOXP3, YNS
The establishment of a predictive mutational model of the forkhead domain through the analyses of FOXC2 missense mutations identified in patients with hereditary lymphedema with distichiasis.
Berry FB, Tamimi Y, Carle MV, Lehmann OJ, Walter MA.
Hum Mol Genet 14(18):2619-27. Epub 2005 Aug 4. 2005
37FOXP2, SPCH1
FOXP2 and the neuroanatomy of speech and language.
Vargha-Khadem F, Gadian DG, Copp A, Mishkin M.
Nat Rev Neurosci 6(2):131-8. Review. 2005
38FOXP2
Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene.
Shu W, Cho JY, Jiang Y, Zhang M, Weisz D, Elder GA, Schmeidler J, De Gasperi R, Sosa MA, Rabidou D, Santucci AC, Perl D, Morrisey E, Buxbaum JD.
Proc Natl Acad Sci U S A. 102(27):9643-8. 2005
39FOXP2
Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.
Li S, Weidenfeld J, Morrisey EE.
Mol Cell Biol. 24(2):809-22 2004
40FOXP2
FoxP2 expression in avian vocal learners and non-learners.
Haesler S, Wada K, Nshdejan A, Morrisey EE, Lints T, Jarvis ED, Scharff C.
J Neurosci. 24(13):3164-75. 2004
41AUTS9, FOXP2
Defining the autism minimum candidate gene region on chromosome 7
Hutcheson HB, Bradford Y, Folstein SE, Gardiner MB, Santangelo SL, Sutcliffe JS, Haines JL.
Am J Med Genet 117B(1):90-6. 2003
42FOXP2
Mutation screening of FOXP2 in individuals diagnosed with autistic disorder.
Gauthier J, Joober R, Mottron L, Laurent S, Fuchs M, De Kimpe V, Rouleau GA.
Am J Med Genet 118A(2):172-5. 2003
43FOXP2, SPCH1
Association of specific language impairment (SLI) to the region of 7q31.
O'Brien EK, Zhang X, Nishimura C, Tomblin JB, Murray JC.
Am J Hum Genet 72(6):1536-43. Epub 2003 Apr 29. 2003
44FOXP2, SPCH1
Expression of Foxp2, a gene involved in speech and language, in the developing and adult striatum.
Takahashi K, Liu FC, Hirokawa K, Takahashi H.
J Neurosci Res 73(1):61-72. 2003
45FOXP2, SPCH1
FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder.
Lai CS, Gerrelli D, Monaco AP, Fisher SE, Copp AJ.
Brain 126(Pt 11):2455-62. Epub 2003 Jul 22. 2003
46FOXP2, SPCH1
Evaluation of FOXP2 as an autism susceptibility gene.
Wassink TH, Piven J, Vieland VJ, Pietila J, Goedken RJ, Folstein SE, Sheffield VC.
Am J Med Genet 114(5):566-9. 2002
47FOXP2, SPCH1
FOXP2: novel exons, splice variants, and CAG repeat length stability.
Bruce HA, Margolis RL.
Hum Genet 111(2):136-44. 2002
48FOXP2, SPCH1
Molecular evolution of FOXP2, a gene involved in speech and language.
Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, Kitano T, Monaco AP, Paabo S.
Nature 418(6900):869-72. 2002
49FOXP2, SPCH1
A forkhead-domain gene is mutated in a severe speech and language disorder.
Lai CS, Fisher SE, Hurst JA, Vargha-Khadem F, Monaco AP.
Nature 413(6855):519-23. 2001
50FOXP2, SPCH1, DEL7Q31
The SPCH1 region on human 7q31: genomic characterization of the critical interval and localization of translocations associated with speech and language disorder.
Lai CS, Fisher SE, Hurst JA, Levy ER, Hodgson S, Fox M, Jeremiah S, Povey S, Jamison DC, Green ED, Vargha-Khadem F, Monaco AP.
Am J Hum Genet 67(2):357-68. 2000
51ATXN2, BHLHE22, CASK, CELF3, CNPY3, EP400, FOXP2, JPH3, KMT2D, MAGI1, MAML3, MED12, MED15, NUMBL, PAXIP1, TNRC15, TNRC17, TNRC18, TNRC6A, TOX3, ZNF384
cDNAs with long CAG trinucleotide repeats from human brain.
Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA.
Hum Genet 100(1):114-22. 1997